Protective effect of the long pentraxin PTX3 against histone-mediated endothelial cell cytotoxicity in sepsis

Science Signaling

Volumn 7, Issue 343, 2014, Pages

  Daigo, Kenji ^a,h   Nakakido, Makoto ^b,i   Ohashi, Riuko ^c,d   Fukuda, Rie ^a   Matsubara, Koichi ^c   Minami, Takashi ^a   Yamaguchi, Naotaka ^e   Inoue, Kenji ^e   Jiang, Shuying ^c,f,g   Naito, Makoto ^c   Tsumoto, Kouhei ^b   Hamakubo, Takao ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^d NIIGATA UNIVERSITY MEDICAL AND DENTAL HOSPITAL   (Japan)

^e JUNTENDO UNIVERSITY NERIMA HOSPITAL   (Japan)

^f Niigata College of Technology   (Japan)

^g Perseus Proteomics   (Japan)

^h HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

ⁱ UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CALCIUM ION; GENTAMICIN; HISTONE; HISTONE H1; HISTONE H3; HISTONE H4; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PENTRAXIN 3; RECOMBINANT PENTRAXIN 3; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN; C REACTIVE PROTEIN; NERVE PROTEIN; NEURONAL PENTRAXIN; PROTEIN BINDING;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL PROTECTION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LUNG HEMORRHAGE; MALE; MORTALITY; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; OLIGOMERIZATION; PATTERN RECOGNITION; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN SECONDARY STRUCTURE; SEPSIS; STOICHIOMETRY; SURVIVAL RATE; THROMBOCYTOPENIA; TRANSMISSION ELECTRON MICROSCOPY; UMBILICAL VEIN ENDOTHELIAL CELL; ANIMAL; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; SURVIVAL;

ANIMALS; C-REACTIVE PROTEIN; ENDOTHELIAL CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HISTONES; IMMUNITY, INNATE; MICE; NERVE TISSUE PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEPSIS; SURVIVAL ANALYSIS;

EID: 84907532236     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2005522     Document Type: Article

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