β-Caryophyllene protects the C6 glioma cells against glutamate-induced excitotoxicity through the Nrf2 pathway

Neuroscience

Volumn 279, Issue , 2014, Pages 220-231

  Assis, L C ^a   Straliotto, M R ^a   Engel, D ^a   Hort, M A ^a   Dutra, R C ^a   de Bem, A F ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

C6 cell line; CB2R; Glutamate; Nrf2 pathway; caryophyllene

Indexed keywords

6 IODO 3 (4 METHOXYBENZOYL) 2 METHYL 1 (2 MORPHOLINOETHYL)INDOLE; CANNABINOID 2 RECEPTOR; CARYOPHYLLENE; GLUTAMIC ACID; GLUTATHIONE; GLUTATHIONE PEROXIDASE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; NEUROPROTECTIVE AGENT; NFE2L2 PROTEIN, RAT; SESQUITERPENE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; ASTROCYTE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; EXCITOTOXICITY; GENE EXPRESSION REGULATION; GLIA CELL; GLIOMA CELL LINE; IN VITRO STUDY; INTRACELLULAR SIGNALING; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN TARGETING; RAT; UPREGULATION; ANIMAL; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; MITOCHONDRION; PHYSIOLOGY; TUMOR CELL LINE;

ANIMALS; ASTROCYTES; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTAMIC ACID; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; RATS; REACTIVE OXYGEN SPECIES; SESQUITERPENES;

EID: 84907484851     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2014.08.043     Document Type: Article

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