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Volumn 64, Issue 3, 2009, Pages 529-538

Evaluation of the antitumoral effect of dihydrocucurbitacin-B in both in vitro and in vivo models

Author keywords

Cyclins; Cytoskeleton; Dihydrocucurbitacin B; Wilbrandia ebracteata

Indexed keywords

CELL CYCLE PROTEIN; CUCURBITACIN; CYCLIN A; CYCLIN B1; DIHYDROCUCURBITACIN B; UNCLASSIFIED DRUG;

EID: 67349202448     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-008-0901-9     Document Type: Article
Times cited : (19)

References (34)
  • 1
    • 0642378446 scopus 로고    scopus 로고
    • Cell cycle deregulation: A common motif in cancer
    • M Malumbres A Carnero 2003 Cell cycle deregulation: a common motif in cancer Prog Cell Cycle Res 5 5 18
    • (2003) Prog Cell Cycle Res , vol.5 , pp. 5-18
    • Malumbres, M.1    Carnero, A.2
  • 2
    • 0029000579 scopus 로고
    • Cyclins and cyclin-dependent kinases: A biochemical view
    • J Pines 1995 Cyclins and cyclin-dependent kinases: a biochemical view Biochem J 308 Pt 3 697 711
    • (1995) Biochem J , vol.308 , Issue.PART 3 , pp. 697-711
    • Pines, J.1
  • 3
    • 18344372831 scopus 로고    scopus 로고
    • Cyclins and cdks in development and cancer: A perspective
    • DOI 10.1038/sj.onc.1208618
    • A Deshpande P Sicinski PW Hinds 2005 Cyclins and cdks in development and cancer: a perspective Oncogene 24 17 2909 2915 (Pubitemid 40638099)
    • (2005) Oncogene , vol.24 , Issue.17 , pp. 2909-2915
    • Deshpande, A.1    Sicinski, P.2    Hinds, P.W.3
  • 4
    • 27844474247 scopus 로고    scopus 로고
    • Drug discovery from medicinal plants
    • DOI 10.1016/j.lfs.2005.09.012, PII S0024320505008799
    • MJ Balunas AD Kinghorn 2005 Drug discovery from medicinal plants Life Sci 78 5 431 441 (Pubitemid 41653493)
    • (2005) Life Sciences , vol.78 , Issue.5 , pp. 431-441
    • Balunas, M.J.1    Kinghorn, A.D.2
  • 6
    • 4043121827 scopus 로고    scopus 로고
    • Podophyllotoxin: Distribution, sources, applications and new cytotoxic derivatives
    • DOI 10.1016/j.toxicon.2004.05.008, PII S0041010104001953
    • M Gordaliza PA Garcia JM del Corral MA Castro MA Gomez-Zurita 2004 Podophyllotoxin: distribution, sources, applications and new cytotoxic derivatives Toxicon 44 4 441 459 (Pubitemid 39070644)
    • (2004) Toxicon , vol.44 , Issue.4 , pp. 441-459
    • Gordaliza, M.1    Garcia, P.A.2    Miguel Del Corral, J.M.3    Castro, M.A.4    Gomez-Zurita, M.A.5
  • 7
    • 1442334562 scopus 로고    scopus 로고
    • Camptothecin and Taxol: Historic Achievements in Natural Products Research
    • DOI 10.1021/np030498t
    • NH Oberlies DJ Kroll 2004 Camptothecin and taxol: historic achievements in natural products research J Nat Prod 67 2 129 135 (Pubitemid 38282896)
    • (2004) Journal of Natural Products , vol.67 , Issue.2 , pp. 129-135
    • Oberlies, N.H.1    Kroll, D.J.2
  • 8
    • 0015194594 scopus 로고
    • The cucurbitanes, a group of tetracyclic triterpenes
    • D Lavie E Glotter 1971 The cucurbitanes, a group of tetracyclic triterpenes Fortschr Chem Org Naturst 29 307 362
    • (1971) Fortschr Chem Org Naturst , vol.29 , pp. 307-362
    • Lavie, D.1    Glotter, E.2
  • 9
    • 33845225917 scopus 로고    scopus 로고
    • Growth inhibitory activity of cucurbitacin glucosides isolated from Citrullus colocynthis on human breast cancer cells
    • TS Tehila G Shlomo D Sara EG Hugo B Margalit 2007 Growth inhibitory activity of cucurbitacin glucosides isolated from Citrullus colocynthis on human breast cancer cells Biochem Pharmacol 73 56 67
    • (2007) Biochem Pharmacol , vol.73 , pp. 56-67
    • Tehila, T.S.1    Shlomo, G.2    Sara, D.3    Hugo, E.G.4    Margalit, B.5
  • 10
    • 0037444373 scopus 로고    scopus 로고
    • Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice
    • MA Blaskovich J Sun A Cantor J Turkson R Jove SM Sebti 2003 Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice Cancer Res 63 1270 1279 (Pubitemid 36348705)
    • (2003) Cancer Research , vol.63 , Issue.6 , pp. 1270-1279
    • Blaskovich, M.A.1    Sun, J.2    Cantor, A.3    Turkson, J.4    Jove, R.5    Sebti, S.M.6
  • 11
    • 18844370367 scopus 로고    scopus 로고
    • Cucurbitacin Q: A selective STAT3 activation inhibitor with potent antitumor activity
    • DOI 10.1038/sj.onc.1208470
    • J Sun MA Blaskovich R Jove SK Livingston D Coppola SM Sebti 2005 Cucurbitacin Q: a selective STAT3 activation inhibitor with potent antitumor activity Oncogene 24 3236 3245 (Pubitemid 40695105)
    • (2005) Oncogene , vol.24 , Issue.20 , pp. 3236-3245
    • Sun, J.1    Blaskovich, M.A.2    Jove, R.3    Livingston, S.K.4    Coppola, D.5    Sebti, S.M.6
  • 12
    • 0030598398 scopus 로고    scopus 로고
    • Cucurbitacin E-induced disruption of the actin and vimentin cytoskeleton in prostate carcinoma cells
    • DOI 10.1016/S0006-2952(96)00557-6, PII S0006295296005576
    • KL Duncan MD Duncan MC Alley EA Sausville 1996 Cucurbitacin E-induced disruption of the actin and vimentin cytoskeleton in prostate carcinoma cells Biochem Pharmacol 52 1553 1560 (Pubitemid 26375461)
    • (1996) Biochemical Pharmacology , vol.52 , Issue.10 , pp. 1553-1560
    • Duncan, K.L.K.1    Duncan, M.D.2    Alley, M.C.3    Sausville, E.A.4
  • 15
    • 33644527555 scopus 로고    scopus 로고
    • Dihydrocucurbitacin B, isolated from Cayaponia tayuya, reduces damage in adjuvant-induced arthritis
    • DOI 10.1016/j.ejphar.2005.12.028, PII S0014299905013336
    • JM Escandell MC Recio S Máñez RM Giner M Cerdás-Nicolás JL Ríos 2006 Dihydrocucurbitacin B, isolated from Cayaponia tayuya, reduces damage in adjuvant-induced arthritis Eur J Pharmacol 532 145 154 (Pubitemid 43295524)
    • (2006) European Journal of Pharmacology , vol.532 , Issue.1-2 , pp. 145-154
    • Escandell, J.M.1    Recio, M.-C.2    Manez, S.3    Giner, R.-M.4    Cerda-Nicolas, M.5    Rios, J.-L.6
  • 16
    • 34548672367 scopus 로고    scopus 로고
    • 2/M cell-cycle arrest and mitochondria-dependent apoptosis in human breast cancer cells (Bcap37)
    • DOI 10.1016/j.canlet.2007.06.018, PII S0304383507002959
    • L Yang S Wu Q Zhang F Liu P Wu 2007 23, 24-Dihydrocucurbitacin B induces G2/M cell-cycle arrest and mitochondria-dependent apoptosis in human breast cancer cells (Bcap37) Cancer Lett 256 267 278 (Pubitemid 47418353)
    • (2007) Cancer Letters , vol.256 , Issue.2 , pp. 267-278
    • Yang, L.1    Wu, S.2    Zhang, Q.3    Liu, F.4    Wu, P.5
  • 17
    • 0027212696 scopus 로고
    • Cucurbitacins as constituents of Wilbrandia ebracteata
    • MR Farias EP Schenkel R Mayer G Rücker 1993 Cucurbitacins as constituents of Wilbrandia ebracteata Planta Med 59 272 275 (Pubitemid 23168780)
    • (1993) Planta Medica , vol.59 , Issue.3 , pp. 272-275
    • Farias, M.R.1    Schenkel, E.P.2    Mayer, R.3    Rucker, G.4
  • 18
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • T Mosmann 1982 Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays J Immunol Meth 65 55 63 (Pubitemid 14203433)
    • (1983) Journal of Immunological Methods , vol.65 , Issue.1-2 , pp. 55-63
    • Mosmann, T.1
  • 19
    • 0017613512 scopus 로고
    • A simplification of the protein assay method of Lowry et al. Which is more generally applicable
    • GL Peterson 1977 A simplification of the protein assay method of Lowry et al. which is more generally applicable Anal Biochem 83 346 356 (Pubitemid 8269786)
    • (1977) Analytical Biochemistry , vol.83 , Issue.2 , pp. 346-356
    • Peterson, G.L.1
  • 22
    • 0031439364 scopus 로고    scopus 로고
    • Anti-inflammatory and analgesic effects of cucurbitacins from Wilbrandia ebracteata
    • DOI 10.1055/s-2006-957755
    • RR Peters MR Farias RM Ribeiro-do-Vale 1997 Anti-inflammatory and analgesic effects of cucurbitacins from W. ebracteata Planta Med 63 525 528 (Pubitemid 28035447)
    • (1997) Planta Medica , vol.63 , Issue.6 , pp. 525-528
    • Peters, R.R.1    Farias, M.R.2    Ribeiro-do-Valle, R.Ma.3
  • 23
    • 0032603225 scopus 로고    scopus 로고
    • Ant-inflammatory effects of the products from Wilbrandia ebracteata on carrageenan-induced pleurisy in mice
    • DOI 10.1016/S0024-3205(99)00200-3, PII S0024320599002003
    • RR Peters TF Saleh M Lora C Patry AJ de Brum-Fernandes MR Farias RM Ribeiro-do-Vale 1999 Anti-inflammatory effects of the products from W. ebracteata on carrageenan-induced pleurisy in mice Life Sci 64 26 2429 2437 (Pubitemid 29268418)
    • (1999) Life Sciences , vol.64 , Issue.26 , pp. 2429-2437
    • Peters, R.R.1    Saleh, T.F.2    Lora, M.3    Patry, C.4    De Brum-Fernandes, A.J.5    Farias, M.R.6    Ribeiro-Do-Valle, R.M.7
  • 25
    • 0033737714 scopus 로고    scopus 로고
    • Effect of serum withdrawal on the proliferation of B16F10 melanoma cells
    • DOI 10.1006/cbir.1999.0502
    • C Rodriguez-Ayerbe I Smith-Zubiaga 2000 Effect of serum withdrawal on the proliferation of B16F10 melanoma cells Cell Biol Int 24 5 279 283 (Pubitemid 30839576)
    • (2000) Cell Biology International , vol.24 , Issue.5 , pp. 279-283
    • Rodriguez-Ayerbe, C.1    Smith-Zubiaga, I.2
  • 26
    • 21244500033 scopus 로고    scopus 로고
    • Cucurbitacinas e suas principais características estruturais
    • LMM Valente 2004 Cucurbitacins and their main structural characteristics Quim Nova 27 6 944 948 (Pubitemid 43092928)
    • (2004) Quimica Nova , vol.27 , Issue.6 , pp. 944-948
    • Valente, L.M.M.1
  • 27
    • 0033735581 scopus 로고    scopus 로고
    • Cell cycle checkpoints and their inactivation in human cancer
    • DOI 10.1046/j.1365-2184.2000.00191.x
    • M Molinari 2000 Cell cycle checkpoints and their inactivation in human cancer Cell Prolif 33 261 274 (Pubitemid 30807736)
    • (2000) Cell Proliferation , vol.33 , Issue.5 , pp. 261-274
    • Molinari, M.1
  • 28
    • 0031914641 scopus 로고    scopus 로고
    • Ubiquitin-dependent degradation of cyclin B is accelerated in polyploid megakaryocytes
    • DOI 10.1074/jbc.273.3.1387
    • Y Zhang Z Wang DX Liu M Pagano K Ravid 1998 Ubiquitin dependent degradation of cyclin B is accelerated in polyploid megakaryocytes J Biol Chem 273 1387 1392 (Pubitemid 28133657)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.3 , pp. 1387-1392
    • Zhang, Y.1    Wang, Z.2    Liu, D.X.3    Pagano, M.4    Ravid, K.5
  • 29
    • 4644372454 scopus 로고    scopus 로고
    • Cholesterol is essential for mitosis progression and its deficiency induces polyploid cell formation
    • DOI 10.1016/j.yexcr.2004.06.029, PII S0014482704003854
    • Fernandez C, Lobo MdMdelV, Gomez-Coronado D, Lasuncion MA (2004) Cholesterol is essential for mitosis progression and its deficiency induces polyploid cell formation. Exp Cell Res 300:109-120 (Pubitemid 39286221)
    • (2004) Experimental Cell Research , vol.300 , Issue.1 , pp. 109-120
    • Fernandez, C.1    Lobo, M.D.V.T.2    Gomez-Coronado, D.3    Lasuncion, M.A.4
  • 31
    • 0026078926 scopus 로고
    • cdc2 kinase during mitosis
    • S Yamashiro Y Yamakita H Hosoya F Matsumura 1991 Phosphorylation of non-muscle caldesmon by p34cdc2 kinase during mitosis Nature 349 169 172 (Pubitemid 21912039)
    • (1991) Nature , vol.349 , Issue.6305 , pp. 169-172
    • Yamashiro, S.1    Yamakita, Y.2    Hosoya, H.3    Matsumura, F.4
  • 32
    • 0026577604 scopus 로고
    • Regulation of intracellular actin polymerization by prenylated cellular proteins
    • RG Fenton HF Kung DL Longo MR Smith 1992 Regulation of intracellular actin polymerization by prenylated cellular proteins J Cell Biol 117 347 356
    • (1992) J Cell Biol , vol.117 , pp. 347-356
    • Fenton, R.G.1    Kung, H.F.2    Longo, D.L.3    Smith, M.R.4
  • 33
    • 0036898535 scopus 로고    scopus 로고
    • Cytokinesis: Rho and formins are the ringleaders
    • TM Huckaba LA Pon 2002 Cytokinesis: rho and formins are the ringleaders Curr Biol 12 23 R813 R814
    • (2002) Curr Biol , vol.12 , Issue.23
    • Huckaba, T.M.1    Pon, L.A.2
  • 34
    • 0642286487 scopus 로고    scopus 로고
    • The actin cytoskeleton as a therapeutic target: State of the art and future directions
    • A Giganti E Friederich 2003 The actin cytoskeleton as a therapeutic target: state of the art and future directions Prog Cell Cycle Res 5 511 525
    • (2003) Prog Cell Cycle Res , vol.5 , pp. 511-525
    • Giganti, A.1    Friederich, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.