Reactive oxygen species from human astrocytes induced functional impairment and oxidative damage

Neurochemical Research

Volumn 38, Issue 10, 2013, Pages 2148-2159

  Sheng, Wen S ^a   Hu, Shuxian ^a   Feng, Amy ^a   Rock, R Bryan ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

8 Isoprostane; Astrocytes; Interleukin 1 beta; Lipid peroxidation; Mitochondria; Reactive oxygen species

Indexed keywords

8 ISOPROSTANE; CATALASE; GAMMA INTERFERON; GLUTAMIC ACID; INTERLEUKIN 1BETA; MANGANESE SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

AMINO ACID TRANSPORT; ARTICLE; ASTROCYTE; CELL ACTIVATION; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME INHIBITION; EXCITOTOXICITY; FETUS; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MITOCHONDRION; NEUROPROTECTION; OXIDATION REDUCTION POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ASTROCYTES; CELLS, CULTURED; DINOPROST; DRUG SYNERGISM; GLUTAMIC ACID; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-1BETA; LIPID PEROXIDATION; MITOCHONDRIA; NADPH OXIDASE; ONIUM COMPOUNDS; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES;

EID: 84884902409     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-013-1123-z     Document Type: Article

References (55)

1. Patten DA, Germain M, Kelly MA, Slack RS (2010) Reactive oxygen species: stuck in the middle of neurodegeneration. J Alzheimers Dis 20(Suppl 2):S357-S367
2. Tabner BJ, Turnbull S, El-Agnaf O, Allsop D (2001) Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases. Curr Top Med Chem 1:507-517
3. Henkel JS, Beers DR, Zhao W, Appel SH (2009) Microglia in ALS: the good, the bad, and the resting. J Neuroimmune Pharmacol 4:389-398
4. Sacktor N, Haughey N, Cutler R, Tamara A, Turchan J, Pardo C, Vargas D, Nath A (2004) Novel markers of oxidative stress in actively progressive HIV dementia. J Neuroimmunol 157:176-184
5. Ito K, Hirao A, Arai F, Takubo K, Matsuoka S, Miyamoto K, Ohmura M, Naka K, Hosokawa K, Ikeda Y, Suda T (2006) Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med 12:446-451
6. Guyton KZ, Liu Y, Gorospe M, Xu Q, Holbrook NJ (1996) Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury. J Biol Chem 271:4138-4142
7. Lo YY, Wong JM, Cruz TF (1996) Reactive oxygen species mediate cytokine activation of c-Jun NH2-terminal kinases. J Biol Chem 271:15703-15707
8. Sena LA, Chandel NS (2012) Physiological roles of mitochondrial reactive oxygen species. Mol Cell 48:158-167
9. Altenhofer S, Kleikers PW, Radermacher KA, Scheurer P, Rob Hermans JJ, Schiffers P, Ho H, Wingler K, Schmidt HH (2012) The NOX toolbox: validating the role of NADPH oxidases in physiology and disease. Cell Mol Life Sci 69:2327-2343
10. Halliwell B (2006) Oxidative stress and neurodegeneration: where are we now? J Neurochem 97:1634-1658
11. Nathan C, Cunningham-Bussel A (2013) Beyond oxidative stress: an immunologist's guide to reactive oxygen species. Nat Rev Immunol 13:349-361
12. Turrens JF (2003) Mitochondrial formation of reactive oxygen species. J Physiol 552:335-344
13. Qian L, Gao X, Pei Z, Wu X, Block M, Wilson B, Hong JS, Flood PM (2007) NADPH oxidase inhibitor DPI is neuroprotective at femtomolar concentrations through inhibition of microglia over-activation. Parkinsonism Relat Disord 13(Suppl 3):S316-S320
14. Cheret C, Gervais A, Lelli A, Colin C, Amar L, Ravassard P, Mallet J, Cumano A, Krause KH, Mallat M (2008) Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase. J Neurosci 28:12039-12051
15. Hu S, Sheng WS, Schachtele SJ, Lokensgard JR (2011) Reactive oxygen species drive herpes simplex virus (HSV)-1-induced proinflammatory cytokine production by murine microglia. J Neuroinflammation 8:123
16. Williams R, Yao H, Peng F, Yang Y, Bethel-Brown C, Buch S (2010) Cooperative induction of CXCL10 involves NADPH oxidase: implications for HIV dementia. Glia 58:611-621
17. Mishra MK, Kumawat KL, Basu A (2008) Japanese encephalitis virus differentially modulates the induction of multiple pro-inflammatory mediators in human astrocytoma and astroglioma cell-lines. Cell Biol Int 32:1506-1513
18. Song HY, Ryu J, Ju SM, Park LJ, Lee JA, Choi SY, Park J (2007) Extracellular HIV-1 Tat enhances monocyte adhesion by up-regulation of ICAM-1 and VCAM-1 gene expression via ROS-dependent NF-kappaB activation in astrocytes. Exp Mol Med 39:27-37
19. Sharma V, Mishra M, Ghosh S, Tewari R, Basu A, Seth P, Sen E (2007) Modulation of interleukin-1beta mediated inflammatory response in human astrocytes by flavonoids: implications in neuroprotection. Brain Res Bull 73:55-63
20. Zhu D, Hu C, Sheng W, Tan KS, Haidekker MA, Sun AY, Sun GY, Lee JC (2009) NAD(P)H oxidase-mediated reactive oxygen species production alters astrocyte membrane molecular order via phospholipase A2. Biochem J 421:201-210
21. Cheng G, Cao Z, Xu X, van Meir EG, Lambeth JD (2001) Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5. Gene 269:131-140
22. Beak SM, Lee YS, Kim JA (2004) NADPH oxidase and cyclooxygenase mediate the ultraviolet B-induced generation of reactive oxygen species and activation of nuclear factor-kappaB in HaCaT human keratinocytes. Biochimie 86:425-429
23. Li Y, Trush MA (1998) Diphenyleneiodonium, an NAD(P)H oxidase inhibitor, also potently inhibits mitochondrial reactive oxygen species production. Biochem Biophys Res Commun 253:295-299
24. Cross AR, Jones OT (1986) The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Specific labelling of a component polypeptide of the oxidase. Biochem J 237:111-116
25. Sugiyama K, Brunori A, Mayer ML (1989) Glial uptake of excitatory amino acids influences neuronal survival in cultures of mouse hippocampus. Neuroscience 32:779-791
26. Lee SC, Dickson DW, Liu W, Brosnan CF (1993) Induction of nitric oxide synthase activity in human astrocytes by interleukin-1 beta and interferon-gamma. J Neuroimmunol 46:19-24
27. Hu S, Sheng WS, Peterson PK, Chao CC (1995) Differential regulation by cytokines of human astrocyte nitric oxide production. Glia 15:491-494
28. Ehrlich LC, Peterson PK, Hu S (1999) Interleukin (IL)-1beta-mediated apoptosis of human astrocytes. NeuroReport 10:1849-1852
29. Thornton P, Pinteaux E, Gibson RM, Allan SM, Rothwell NJ (2006) Interleukin-1-induced neurotoxicity is mediated by glia and requires caspase activation and free radical release. J Neurochem 98:258-266
30. Lee SC, Liu W, Dickson DW, Brosnan CF, Berman JW (1993) Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta. J Immunol 150:2659-2667
31. Rivieccio MA, John GR, Song X, Suh HS, Zhao Y, Lee SC, Brosnan CF (2005) The cytokine IL-1beta activates IFN response factor 3 in human fetal astrocytes in culture. J Immunol 174:3719-3726
32. Hu S, Sheng WS, Ehrlich LC, Peterson PK, Chao CC (2000) Cytokine effects on glutamate uptake by human astrocytes. NeuroImmunoModulation 7:153-159
33. Hoffman SW, Rzigalinski BA, Willoughby KA, Ellis EF (2000) Astrocytes generate isoprostanes in response to trauma or oxygen radicals. J Neurotrauma 17:415-420
34. Chao CC, Hu S, Sheng WS, Bu D, Bukrinsky MI, Peterson PK (1996) Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism. Glia 16:276-284
35. Piani D, Frei K, Pfister HW, Fontana A (1993) Glutamate uptake by astrocytes is inhibited by reactive oxygen intermediates but not by other macrophage-derived molecules including cytokines, leukotrienes or platelet-activating factor. J Neuroimmunol 48:99-104
36. Volterra A, Trotti D, Tromba C, Floridi S, Racagni G (1994) Glutamate uptake inhibition by oxygen free radicals in rat cortical astrocytes. J Neurosci 14:2924-2932
37. Sorg O, Horn TF, Yu N, Gruol DL, Bloom FE (1997) Inhibition of astrocyte glutamate uptake by reactive oxygen species: role of antioxidant enzymes. Mol Med 3:431-440
38. Sher PK, Hu SX (1990) Increased glutamate uptake and glutamine synthetase activity in neuronal cell cultures surviving chronic hypoxia. Glia 3:350-357
39. McCubrey JA, Lahair MM, Franklin RA (2006) Reactive oxygen species-induced activation of the MAP kinase signaling pathways. Antioxid Redox Signal 8:1775-1789
40. Morrow JD, Hill KE, Burk RF, Nammour TM, Badr KF, Roberts LJ 2nd (1990) A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism. Proc Natl Acad Sci USA 87:9383-9387
41. Block ML, Li G, Qin L, Wu X, Pei Z, Wang T, Wilson B, Yang J, Hong JS (2006) Potent regulation of microglia-derived oxidative stress and dopaminergic neuron survival: substance P vs. dynorphin. Faseb J 20:251-258
42. Huo Y, Rangarajan P, Ling EA, Dheen ST (2011) Dexamethasone inhibits the Nox-dependent ROS production via suppression of MKP-1-dependent MAPK pathways in activated microglia. BMC Neurosci 12:49
43. Dohi K, Ohtaki H, Nakamachi T, Yofu S, Satoh K, Miyamoto K, Song D, Tsunawaki S, Shioda S, Aruga T (2010) Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury. J Neuroinflammation 7:41
44. Sheng WS, Hu S, Nettles AR, Lokensgard JR, Vercellotti GM, Rock RB (2010) Hemin inhibits NO production by IL-1beta-stimulated human astrocytes through induction of heme oxygenase-1 and reduction of p38 MAPK activation. J Neuroinflammation 7:51
45. Schroder K, Hertzog PJ, Ravasi T, Hume DA (2004) Interferon-gamma: an overview of signals, mechanisms and functions. J Leukoc Biol 75:163-189
46. Block K, Gorin Y, Abboud HE (2009) Subcellular localization of Nox4 and regulation in diabetes. Proc Natl Acad Sci USA 106:14385-14390
47. Jou MJ (2008) Pathophysiological and pharmacological implications of mitochondria-targeted reactive oxygen species generation in astrocytes. Adv Drug Deliv Rev 60:1512-1526
48. Wenk J, Brenneisen P, Wlaschek M, Poswig A, Briviba K, Oberley TD, Scharffetter-Kochanek K (1999) Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major oxidant in the AP-1-mediated induction of matrix-degrading metalloprotease-1. J Biol Chem 274:25869-25876
49. Rodriguez AM, Carrico PM, Mazurkiewicz JE, Melendez JA (2000) Mitochondrial or cytosolic catalase reverses the MnSOD-dependent inhibition of proliferation by enhancing respiratory chain activity, net ATP production, and decreasing the steady state levels of H(2)O(2). Free Radic Biol Med 29:801-813
50. Ranganathan AC, Nelson KK, Rodriguez AM, Kim KH, Tower GB, Rutter JL, Brinckerhoff CE, Huang TT, Epstein CJ, Jeffrey JJ, Melendez JA (2001) Manganese superoxide dismutase signals matrix metalloproteinase expression via H2O2-dependent ERK1/2 activation. J Biol Chem 276:14264-14270
51. Torres M (2003) Mitogen-activated protein kinase pathways in redox signaling. Front Biosci 8:d369-d391
52. Morrow JD (2006) The isoprostanes - unique products of arachidonate peroxidation: their role as mediators of oxidant stress. Curr Pharm Des 12:895-902
53. Ogawa F, Shimizu K, Muroi E, Hara T, Hasegawa M, Takehara K, Sato S (2006) Serum levels of 8-isoprostane, a marker of oxidative stress, are elevated in patients with systemic sclerosis. Rheumatology (Oxford) 45:815-818
54. Chao CC, Hu S, Ehrlich L, Peterson PK (1995) Interleukin-1 and tumor necrosis factor-alpha synergistically mediate neurotoxicity: involvement of nitric oxide and of N-methyl-D-aspartate receptors. Brain Behav Immun 9:355-365
55. Ouyang YB, Voloboueva LA, Xu LJ, Giffard RG (2007) Selective dysfunction of hippocampal CA1 astrocytes contributes to delayed neuronal damage after transient forebrain ischemia. J Neurosci 27:4253-4260