The anti-inflammatory effects of dimethyl fumarate in astrocytes involve glutathione and haem oxygenase-1

ASN Neuro

Volumn 3, Issue 2, 2011, Pages 75-84

  Lin, Shao Xia ^a   Lisi, Lucia ^b   Dello Russo, Cinzia ^b   Polak, Paul E ^a   Sharp, Anthony ^a   Weinberg, Guy ^a,c   Kalinin, Sergey ^a   Feinstein, Douglas L ^a,c  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b CATHOLIC UNIVERSITY   (Italy)

^c JESSE BROWN VA MEDICAL CENTER   (United States)

Author keywords

Glial cells; Glutathione; Inflammation; Multiple sclerosis; Nitric oxide synthase 2 (NOS2)

Indexed keywords

FUMARIC ACID DIMETHYL ESTER; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE SYNTHASE; HEME OXYGENASE 1; I KAPPA B KINASE ALPHA; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NITRITE; TRANSCRIPTION FACTOR NRF2; TRANSCRIPTION FACTOR RELA; ANTIINFLAMMATORY AGENT; FUMARIC ACID DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOSUPPRESSIVE AGENT;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ASTROCYTE; CELL LEVEL; CELL NUCLEUS; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; GENE ACTIVATION; GLIOMA CELL; NONHUMAN; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN LOCALIZATION; RAT; RNA ANALYSIS; TRANSCRIPTION INITIATION; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ASTROCYTES; CELLS, CULTURED; FUMARATES; GLUTATHIONE; HEME OXYGENASE-1; HUMANS; IMMUNOSUPPRESSIVE AGENTS; NF-E2-RELATED FACTOR 2; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

EID: 79958153194     PISSN: None     EISSN: 17590914     Source Type: Journal    
DOI: 10.1042/AN20100033     Document Type: Article

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