Sodium-glucose transporter-2 (SGLT2; SLC5A2) enhances cellular uptake of aminoglycosides

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Jiang, Meiyan ^a   Wang, Qi ^a   Karasawa, Takatoshi ^a   Koo, Ja Won ^a,b   Li, Hongzhe ^a   Steyger, Peter S ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b Seoul National University Bundang Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; GENTAMICIN; GLUCOSE; KANAMYCIN; PHLORIZIN; SMALL INTERFERING RNA; SODIUM GLUCOSE COTRANSPORTER 2; 2-(N-(7-NITROBENZ-2-OXA-1,3-DIAZOL-4-YL)AMINO)-2-DEOXYGLUCOSE; 4 CHLORO 7 NITROBENZOFURAZAN; ANTIINFECTIVE AGENT; DEOXYGLUCOSE; FLUORESCENT DYE; SLC5A2 PROTEIN, MOUSE; SODIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COCHLEA; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CYTOTOXICITY; DRUG TRANSPORT; DRUG UPTAKE; EVOKED BRAIN STEM AUDITORY RESPONSE; HETEROLOGOUS EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MOUSE; NONHUMAN; OTOTOXICITY; PROTEIN EXPRESSION; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; ANTIBODY SPECIFICITY; CELL LINE; CYTOLOGY; DRUG EFFECTS; FEMALE; GENE EXPRESSION; GENETICS; HEARING TEST; KIDNEY DISTAL TUBULE; KINETICS; MALE; METABOLISM; PHYSIOLOGY; TRANSGENIC MOUSE; TRANSPORT AT THE CELLULAR LEVEL;

4-CHLORO-7-NITROBENZOFURAZAN; ANIMALS; ANTI-BACTERIAL AGENTS; BIOLOGICAL TRANSPORT; CELL LINE; COCHLEA; DEOXYGLUCOSE; FEMALE; FLUORESCENT DYES; GENE EXPRESSION; GENTAMICINS; HEARING TESTS; KANAMYCIN; KIDNEY TUBULES, DISTAL; KIDNEY TUBULES, PROXIMAL; KINETICS; MALE; MICE; MICE, TRANSGENIC; ORGAN SPECIFICITY; PHLORHIZIN; RNA, SMALL INTERFERING; SODIUM; SODIUM-GLUCOSE TRANSPORTER 2;

EID: 84907484530     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0108941     Document Type: Article

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