메뉴 건너뛰기




Volumn 67, Issue , 2013, Pages 16-24

Orexin A regulates cardiovascular responses in stress-induced hypertensive rats

Author keywords

Heart rate; Lateral hypothalamus; Nitric oxide synthase nitric oxide; Orexin A; Rostral ventrolateral medulla; Stress induced hypertension; Systolic blood pressure

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; NEUROFILAMENT PROTEIN; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OREXIN 1 RECEPTOR; OREXIN 2 RECEPTOR; OREXIN A;

EID: 84873362780     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.10.021     Document Type: Article
Times cited : (72)

References (54)
  • 1
    • 78649811835 scopus 로고    scopus 로고
    • Trends in hypertension prevalence, awareness, treatment and control in older Mexican Americans, 1993-2005
    • M. Al Ghatrif, Y.F. Kuo, S. Al Snih, M.A. Raji, L.A. Ray, and K.S. Markides Trends in hypertension prevalence, awareness, treatment and control in older Mexican Americans, 1993-2005 Ann. Epidemiol. 21 2011 15 25
    • (2011) Ann. Epidemiol. , vol.21 , pp. 15-25
    • Al Ghatrif, M.1    Kuo, Y.F.2    Al Snih, S.3    Raji, M.A.4    Ray, L.A.5    Markides, K.S.6
  • 3
    • 0000707453 scopus 로고
    • Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations
    • W.P. Arnold, C.K. Mittal, S. Katsuki, and F. Murad Nitric oxide activates guanylate cyclase and increases guanosine 3′:5′-cyclic monophosphate levels in various tissue preparations Proc. Natl. Acad. Sci. U. S. A. 74 1977 3203 3207
    • (1977) Proc. Natl. Acad. Sci. U. S. A. , vol.74 , pp. 3203-3207
    • Arnold, W.P.1    Mittal, C.K.2    Katsuki, S.3    Murad, F.4
  • 4
    • 59349089712 scopus 로고    scopus 로고
    • The brain hypocretins and their receptors: Mediators of allostatic arousal
    • M.E. Carter, J.S. Borg, and L. de Lecea The brain hypocretins and their receptors: mediators of allostatic arousal Curr. Opin. Pharmacol. 9 2009 39 45
    • (2009) Curr. Opin. Pharmacol. , vol.9 , pp. 39-45
    • Carter, M.E.1    Borg, J.S.2    De Lecea, L.3
  • 5
    • 1942500891 scopus 로고    scopus 로고
    • Differential contributions of NOS isoforms in the rostral ventrolateral medulla to cardiovascular responses associated with mevinphos intoxication in the rat
    • J.Y. Chan, S.H. Chan, and A.Y. Chang Differential contributions of NOS isoforms in the rostral ventrolateral medulla to cardiovascular responses associated with mevinphos intoxication in the rat Neuropharmacology 46 2004 1184 1194
    • (2004) Neuropharmacology , vol.46 , pp. 1184-1194
    • Chan, J.Y.1    Chan, S.H.2    Chang, A.Y.3
  • 6
    • 11144294755 scopus 로고    scopus 로고
    • Phasic cardiovascular responses to mevinphos are mediated through differential activation of cGMP/PKG cascade and peroxynitrite via nitric oxide generated in the rat rostral ventrolateral medulla by NOS i and II isoforms
    • J.Y. Chan, S.H. Chan, F.C. Li, C.Y. Tsai, H.L. Cheng, and A.Y. Chang Phasic cardiovascular responses to mevinphos are mediated through differential activation of cGMP/PKG cascade and peroxynitrite via nitric oxide generated in the rat rostral ventrolateral medulla by NOS I and II isoforms Neuropharmacology 48 2005 161 172
    • (2005) Neuropharmacology , vol.48 , pp. 161-172
    • Chan, J.Y.1    Chan, S.H.2    Li, F.C.3    Tsai, C.Y.4    Cheng, H.L.5    Chang, A.Y.6
  • 7
    • 0037295353 scopus 로고    scopus 로고
    • Differential engagements of glutamate and GABA receptors in cardiovascular actions of endogenous nNOS or iNOS at rostral ventrolateral medulla of rats
    • S.H. Chan, L.L. Wang, and J.Y. Chan Differential engagements of glutamate and GABA receptors in cardiovascular actions of endogenous nNOS or iNOS at rostral ventrolateral medulla of rats Br. J. Pharmacol. 138 2003 584 593
    • (2003) Br. J. Pharmacol. , vol.138 , pp. 584-593
    • Chan, S.H.1    Wang, L.L.2    Chan, J.Y.3
  • 8
    • 0034950735 scopus 로고    scopus 로고
    • Differential cardiovascular responses to blockade of nNOS or iNOS in rostral ventrolateral medulla of the rat
    • S.H. Chan, L.L. Wang, S.H. Wang, and J.Y. Chan Differential cardiovascular responses to blockade of nNOS or iNOS in rostral ventrolateral medulla of the rat Br. J. Pharmacol. 133 2001 606 614
    • (2001) Br. J. Pharmacol. , vol.133 , pp. 606-614
    • Chan, S.H.1    Wang, L.L.2    Wang, S.H.3    Chan, J.Y.4
  • 9
    • 0037262643 scopus 로고    scopus 로고
    • Differential distribution of nitric oxide synthase isoforms in the rostral ventrolateral medulla of the rat
    • A.Y. Chang, J.Y. Chan, and S.H. Chan Differential distribution of nitric oxide synthase isoforms in the rostral ventrolateral medulla of the rat J. Biomed. Sci. 10 2003 285 291
    • (2003) J. Biomed. Sci. , vol.10 , pp. 285-291
    • Chang, A.Y.1    Chan, J.Y.2    Chan, S.H.3
  • 10
    • 33847125744 scopus 로고    scopus 로고
    • Inhibitory effects of an orexin-2 receptor antagonist on orexin A- and stress-induced ACTH responses in conscious rats
    • H. Chang, T. Saito, N. Ohiwa, M. Tateoka, C.C. Deocaris, T. Fujikawa, and H. Soya Inhibitory effects of an orexin-2 receptor antagonist on orexin A- and stress-induced ACTH responses in conscious rats Neurosci. Res. 57 2007 462 466
    • (2007) Neurosci. Res. , vol.57 , pp. 462-466
    • Chang, H.1    Saito, T.2    Ohiwa, N.3    Tateoka, M.4    Deocaris, C.C.5    Fujikawa, T.6    Soya, H.7
  • 13
    • 0034062230 scopus 로고    scopus 로고
    • Pressor effects of orexins injected intracisternally and to rostral ventrolateral medulla of anesthetized rats
    • C.T. Chen, L.L. Hwang, J.K. Chang, and N.J. Dun Pressor effects of orexins injected intracisternally and to rostral ventrolateral medulla of anesthetized rats Am. J. Physiol. Regul. Integr. Comp. Physiol. 278 2000 R692 R697
    • (2000) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.278
    • Chen, C.T.1    Hwang, L.L.2    Chang, J.K.3    Dun, N.J.4
  • 14
    • 0037404648 scopus 로고    scopus 로고
    • Morphological study of orexin neurons in the hypothalamus of the Long-Evans rat, with special reference to co-expression of orexin and NADPH-diaphorase or nitric oxide synthase activities
    • S.B. Cheng, S. Kuchiiwa, H.Z. Gao, T. Kuchiiwa, and S. Nakagawa Morphological study of orexin neurons in the hypothalamus of the Long-Evans rat, with special reference to co-expression of orexin and NADPH-diaphorase or nitric oxide synthase activities Neurosci. Res. 46 2003 53 62
    • (2003) Neurosci. Res. , vol.46 , pp. 53-62
    • Cheng, S.B.1    Kuchiiwa, S.2    Gao, H.Z.3    Kuchiiwa, T.4    Nakagawa, S.5
  • 16
    • 0142122405 scopus 로고    scopus 로고
    • Cardioacceleratory responses to hypocretin-1 injections into rostral ventromedial medulla
    • J. Ciriello, Z. Li, and C.V. de Oliveira Cardioacceleratory responses to hypocretin-1 injections into rostral ventromedial medulla Brain Res. 991 2003 84 95
    • (2003) Brain Res. , vol.991 , pp. 84-95
    • Ciriello, J.1    Li, Z.2    De Oliveira, C.V.3
  • 17
    • 0037086842 scopus 로고    scopus 로고
    • Protein distribution of the orexin-2 receptor in the rat central nervous system
    • J.E. Cluderay, D.C. Harrison, and G.J. Hervieu Protein distribution of the orexin-2 receptor in the rat central nervous system Regul. Pept. 104 2002 131 144
    • (2002) Regul. Pept. , vol.104 , pp. 131-144
    • Cluderay, J.E.1    Harrison, D.C.2    Hervieu, G.J.3
  • 18
    • 75749108530 scopus 로고    scopus 로고
    • A decade of hypocretins: Past, present and future of the neurobiology of arousal
    • L. de Lecea A decade of hypocretins: past, present and future of the neurobiology of arousal Acta Physiol. (Oxf.) 198 2010 203 208
    • (2010) Acta Physiol. (Oxf.) , vol.198 , pp. 203-208
    • De Lecea, L.1
  • 20
    • 33846487238 scopus 로고    scopus 로고
    • Role of orexin in the cholinergic ascending arousal system-orexin-induced arousal from anesthesia
    • S. Fukuda, Z. Zhu, and S. Morita Role of orexin in the cholinergic ascending arousal system-orexin-induced arousal from anesthesia Masui 56 2007 19 29
    • (2007) Masui , vol.56 , pp. 19-29
    • Fukuda, S.1    Zhu, Z.2    Morita, S.3
  • 21
    • 70350231772 scopus 로고    scopus 로고
    • Hypocretin/orexin contributes to the expression of some but not all forms of stress and arousal
    • T.M. Furlong, D.M. Vianna, L. Liu, and P. Carrive Hypocretin/orexin contributes to the expression of some but not all forms of stress and arousal Eur. J. Neurosci. 30 2009 1603 1614
    • (2009) Eur. J. Neurosci. , vol.30 , pp. 1603-1614
    • Furlong, T.M.1    Vianna, D.M.2    Liu, L.3    Carrive, P.4
  • 22
    • 70349619677 scopus 로고    scopus 로고
    • Nitric oxide in rostral ventrolateral medulla regulates cardiac-sympathetic reflexes: Role of synthase isoforms
    • Z.L. Guo, A.L.S.C. Tjen, L.W. Fu, and J.C. Longhurst Nitric oxide in rostral ventrolateral medulla regulates cardiac-sympathetic reflexes: role of synthase isoforms Am. J. Physiol. Heart Circ. Physiol. 297 2009 H1478 H1486
    • (2009) Am. J. Physiol. Heart Circ. Physiol. , vol.297
    • Guo, Z.L.1    Tjen, A.L.S.C.2    Fu, L.W.3    Longhurst, J.C.4
  • 23
  • 24
    • 0026024993 scopus 로고
    • Cardiovascular response to stress
    • J.A. Herd Cardiovascular response to stress Physiol. Rev. 71 1991 305 330
    • (1991) Physiol. Rev. , vol.71 , pp. 305-330
    • Herd, J.A.1
  • 25
    • 0141463751 scopus 로고    scopus 로고
    • Effects of central hypocretin-1 administration on hemodynamic responses in young-adult and middle-aged rats
    • K. Hirota, T. Kushikata, M. Kudo, T. Kudo, D. Smart, and A. Matsuki Effects of central hypocretin-1 administration on hemodynamic responses in young-adult and middle-aged rats Brain Res. 981 2003 143 150
    • (2003) Brain Res. , vol.981 , pp. 143-150
    • Hirota, K.1    Kushikata, T.2    Kudo, M.3    Kudo, T.4    Smart, D.5    Matsuki, A.6
  • 26
    • 77954944602 scopus 로고    scopus 로고
    • Orexins depolarize rostral ventrolateral medulla neurons and increase arterial pressure and heart rate in rats mainly via orexin 2 receptors
    • S.C. Huang, Y.W. Dai, Y.H. Lee, L.C. Chiou, and L.L. Hwang Orexins depolarize rostral ventrolateral medulla neurons and increase arterial pressure and heart rate in rats mainly via orexin 2 receptors J. Pharmacol. Exp. Ther. 334 2010 522 529
    • (2010) J. Pharmacol. Exp. Ther. , vol.334 , pp. 522-529
    • Huang, S.C.1    Dai, Y.W.2    Lee, Y.H.3    Chiou, L.C.4    Hwang, L.L.5
  • 27
    • 33645320013 scopus 로고    scopus 로고
    • Effects of acupuncture on nNOS and iNOS expression in the rostral ventrolateral medulla of stress-induced hypertensive rats
    • Y.L. Huang, M.X. Fan, J. Wang, L. Li, N. Lu, Y.X. Cao, L.L. Shen, and D.N. Zhu Effects of acupuncture on nNOS and iNOS expression in the rostral ventrolateral medulla of stress-induced hypertensive rats Acupunct. Electrother. Res. 30 2005 263 273
    • (2005) Acupunct. Electrother. Res. , vol.30 , pp. 263-273
    • Huang, Y.L.1    Fan, M.X.2    Wang, J.3    Li, L.4    Lu, N.5    Cao, Y.X.6    Shen, L.L.7    Zhu, D.N.8
  • 28
    • 80051793068 scopus 로고    scopus 로고
    • Adenosine A(2A)R modulates cardiovascular function by activating ERK1/2 signal in the rostral ventrolateral medulla of acute myocardial ischemic rats
    • M. Jiang, C. Zhang, J. Wang, J. Chen, C. Xia, D. Du, N. Zhao, Y. Cao, L. Shen, and D. Zhu Adenosine A(2A)R modulates cardiovascular function by activating ERK1/2 signal in the rostral ventrolateral medulla of acute myocardial ischemic rats Life Sci. 89 2011 182 187
    • (2011) Life Sci. , vol.89 , pp. 182-187
    • Jiang, M.1    Zhang, C.2    Wang, J.3    Chen, J.4    Xia, C.5    Du, D.6    Zhao, N.7    Cao, Y.8    Shen, L.9    Zhu, D.10
  • 29
    • 79956305923 scopus 로고    scopus 로고
    • Nitric oxide modulates cardiovascular function in the rat by activating adenosine A2A receptors and inhibiting acetylcholine release in the rostral ventrolateral medulla
    • M.Y. Jiang, J. Chen, J. Wang, F. Xiao, H.H. Zhang, C.R. Zhang, D.S. Du, Y.X. Cao, L.L. Shen, and D.N. Zhu Nitric oxide modulates cardiovascular function in the rat by activating adenosine A2A receptors and inhibiting acetylcholine release in the rostral ventrolateral medulla Clin. Exp. Pharmacol. Physiol. 38 2011 380 386
    • (2011) Clin. Exp. Pharmacol. Physiol. , vol.38 , pp. 380-386
    • Jiang, M.Y.1    Chen, J.2    Wang, J.3    Xiao, F.4    Zhang, H.H.5    Zhang, C.R.6    Du, D.S.7    Cao, Y.X.8    Shen, L.L.9    Zhu, D.N.10
  • 30
    • 33846492891 scopus 로고    scopus 로고
    • Central action of orexins on sympathetic outflow and cardiovascular function with a focus on the paraventricular nucleus of the hypothalamus
    • H. Kannan, T. Shirasaka, S. Watanabe, N.S. Yu, T. Kuitake, and M. Takasaki Central action of orexins on sympathetic outflow and cardiovascular function with a focus on the paraventricular nucleus of the hypothalamus Masui 56 2007 30 39
    • (2007) Masui , vol.56 , pp. 30-39
    • Kannan, H.1    Shirasaka, T.2    Watanabe, S.3    Yu, N.S.4    Kuitake, T.5    Takasaki, M.6
  • 32
    • 0035726144 scopus 로고    scopus 로고
    • Overexpression of eNOS in the RVLM causes hypotension and bradycardia via GABA release
    • T. Kishi, Y. Hirooka, K. Sakai, H. Shigematsu, H. Shimokawa, and A. Takeshita Overexpression of eNOS in the RVLM causes hypotension and bradycardia via GABA release Hypertension 38 2001 896 901
    • (2001) Hypertension , vol.38 , pp. 896-901
    • Kishi, T.1    Hirooka, Y.2    Sakai, K.3    Shigematsu, H.4    Shimokawa, H.5    Takeshita, A.6
  • 33
    • 0242501518 scopus 로고    scopus 로고
    • Single CNS neurons link both central motor and cardiosympathetic systems: A double-virus tracing study
    • K.E. Krout, T.C. Mettenleiter, and A.D. Loewy Single CNS neurons link both central motor and cardiosympathetic systems: a double-virus tracing study Neuroscience 118 2003 853 866
    • (2003) Neuroscience , vol.118 , pp. 853-866
    • Krout, K.E.1    Mettenleiter, T.C.2    Loewy, A.D.3
  • 34
    • 80051625862 scopus 로고    scopus 로고
    • Stress induced hypertensive response: Should it be evaluated more carefully?
    • N. Kucukler, F. Yalcin, T.P. Abraham, and M.J. Garcia Stress induced hypertensive response: should it be evaluated more carefully? Cardiovasc. Ultrasound 9 2011 22
    • (2011) Cardiovasc. Ultrasound , vol.9 , pp. 22
    • Kucukler, N.1    Yalcin, F.2    Abraham, T.P.3    Garcia, M.J.4
  • 35
    • 78049402675 scopus 로고    scopus 로고
    • Orexin neurons as arousal-associated modulators of central cardiorespiratory regulation
    • T. Kuwaki, and W. Zhang Orexin neurons as arousal-associated modulators of central cardiorespiratory regulation Respir. Physiol. Neurobiol. 174 2010 43 54
    • (2010) Respir. Physiol. Neurobiol. , vol.174 , pp. 43-54
    • Kuwaki, T.1    Zhang, W.2
  • 38
    • 0037086827 scopus 로고    scopus 로고
    • Pressor response to microinjection of orexin/hypocretin into rostral ventrolateral medulla of awake rats
    • B.H. Machado, L.G. Bonagamba, S.L. Dun, E.H. Kwok, and N.J. Dun Pressor response to microinjection of orexin/hypocretin into rostral ventrolateral medulla of awake rats Regul. Pept. 104 2002 75 81
    • (2002) Regul. Pept. , vol.104 , pp. 75-81
    • MacHado, B.H.1    Bonagamba, L.G.2    Dun, S.L.3    Kwok, E.H.4    Dun, N.J.5
  • 40
    • 33845658084 scopus 로고    scopus 로고
    • Differential influence of iNOS and nNOS inhibitors on rostral ventrolateral medullary mediated cardiovascular control in conscious rats
    • M.C. Martins-Pinge, M.R. Garcia, D.B. Zoccal, C.C. Crestani, and P. Pinge-Filho Differential influence of iNOS and nNOS inhibitors on rostral ventrolateral medullary mediated cardiovascular control in conscious rats Auton. Neurosci. 131 2007 65 69
    • (2007) Auton. Neurosci. , vol.131 , pp. 65-69
    • Martins-Pinge, M.C.1    Garcia, M.R.2    Zoccal, D.B.3    Crestani, C.C.4    Pinge-Filho, P.5
  • 44
    • 77954566931 scopus 로고    scopus 로고
    • The orexin system: Roles in sleep/wake regulation
    • T. Sakurai, M. Mieda, and N. Tsujino The orexin system: roles in sleep/wake regulation Ann. N. Y. Acad. Sci. 1200 2010 149 161
    • (2010) Ann. N. Y. Acad. Sci. , vol.1200 , pp. 149-161
    • Sakurai, T.1    Mieda, M.2    Tsujino, N.3
  • 46
    • 79251497363 scopus 로고    scopus 로고
    • Intrathecal orexin A increases sympathetic outflow and respiratory drive, enhances baroreflex sensitivity and blocks the somato-sympathetic reflex
    • I.Z. Shahid, A.A. Rahman, and P.M. Pilowsky Intrathecal orexin A increases sympathetic outflow and respiratory drive, enhances baroreflex sensitivity and blocks the somato-sympathetic reflex Br. J. Pharmacol. 162 2011 961 973
    • (2011) Br. J. Pharmacol. , vol.162 , pp. 961-973
    • Shahid, I.Z.1    Rahman, A.A.2    Pilowsky, P.M.3
  • 47
    • 35448944868 scopus 로고    scopus 로고
    • Nitric oxide and GABA mediate bi-directional cardiovascular effects of orexin in the nucleus tractus solitarii of rats
    • C.D. Shih, and Y.C. Chuang Nitric oxide and GABA mediate bi-directional cardiovascular effects of orexin in the nucleus tractus solitarii of rats Neuroscience 149 2007 625 635
    • (2007) Neuroscience , vol.149 , pp. 625-635
    • Shih, C.D.1    Chuang, Y.C.2
  • 51
    • 0035860526 scopus 로고    scopus 로고
    • The nNOS/cGMP signal transducing system is involved in the cardiovascular responses induced by activation of NMDA receptors in the rostral ventrolateral medulla of cats
    • W.C. Wu, Y. Wang, C.K. Su, and C.Y. Chai The nNOS/cGMP signal transducing system is involved in the cardiovascular responses induced by activation of NMDA receptors in the rostral ventrolateral medulla of cats Neurosci. Lett. 310 2001 121 124
    • (2001) Neurosci. Lett. , vol.310 , pp. 121-124
    • Wu, W.C.1    Wang, Y.2    Su, C.K.3    Chai, C.Y.4
  • 54
    • 33744523416 scopus 로고    scopus 로고
    • Multiple components of the defense response depend on orexin: Evidence from orexin knockout mice and orexin neuron-ablated mice
    • W. Zhang, M. Shimoyama, Y. Fukuda, and T. Kuwaki Multiple components of the defense response depend on orexin: evidence from orexin knockout mice and orexin neuron-ablated mice Auton. Neurosci. 126-127 2006 139 145
    • (2006) Auton. Neurosci. , vol.126-127 , pp. 139-145
    • Zhang, W.1    Shimoyama, M.2    Fukuda, Y.3    Kuwaki, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.