An activatable prodrug for the treatment of metastatic tumors

Journal of the American Chemical Society

Volumn 136, Issue 39, 2014, Pages 13888-13894

  Kim, Eun Joong ^a   Bhuniya, Sankarprasad ^a,d   Lee, Hyunseung ^a   Kim, Hyun Min ^a   Cheong, Chaejoon ^a,b   Maiti, Sukhendu ^c   Hong, Kwan Soo ^a,b   Kim, Jong Seung ^c  

^a Korea Basic Science Institute (KBSI)   (South Korea)

^b University of Science and Technology (UST)   (South Korea)

^c Korea University   (South Korea)

^d AMRITA UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; DRUG PRODUCTS; FLUORESCENCE;

ANTI-TUMOR ACTIVITIES; ANTICANCER DRUG; CELLULAR IMAGING; METASTATIC CANCERS; METASTATIC TUMORS; REACTIVE OXYGEN SPECIES; THERAPEUTIC AGENTS; THERAPEUTIC POTENTIALS;

TUMORS;

BORONIC ACID DERIVATIVE; FIRTECAN; HYDROGEN PEROXIDE; PRODRUG; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; IRINOTECAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG EFFECT; DRUG RELEASE; DRUG SYNTHESIS; FLUORESCENCE; HUMAN; HUMAN CELL; LUNG METASTASIS; MOUSE; NONHUMAN; OXIDATION; TUMOR GROWTH; ANALOGS AND DERIVATIVES; ANIMAL; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; HELA CELL LINE; LUNG NEOPLASMS; METABOLISM; NEOPLASMS, EXPERIMENTAL; SECONDARY; STRUCTURE ACTIVITY RELATION; TUMOR CELL CULTURE;

ANIMALS; ANTINEOPLASTIC AGENTS; CAMPTOTHECIN; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; HELA CELLS; HUMANS; HYDROGEN PEROXIDE; LUNG NEOPLASMS; MICE; MOLECULAR STRUCTURE; NEOPLASMS, EXPERIMENTAL; PRODRUGS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84907483939     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja5077684     Document Type: Article

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