Hydrogen peroxide inducible DNA cross-linking agents: Targeted anticancer prodrugs

Journal of the American Chemical Society

Volumn 133, Issue 48, 2011, Pages 19278-19281

  Kuang, Yunyan ^a,b   Balakrishnan, Kumudha ^c   Gandhi, Varsha ^c   Peng, Xiaohua ^a  

^a UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^b FUDAN UNIVERSITY   (China)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION MECHANISMS; CANCER CELLS; CHEMOTHERAPEUTIC AGENTS; CHEMOTHERAPY AGENTS; CROSS LINKING AGENTS; DNA ALKYLATIONS; INTERSTRAND CROSS-LINKS; NITROGEN MUSTARDS; NMR ANALYSIS; PRODRUGS; REACTIVE OXYGEN SPECIES; THERAPEUTIC ACTIVITY;

ACTIVATION ANALYSIS; CHEMOTHERAPY; CROSSLINKING; DISEASES; DNA; HYDROGEN; HYDROGEN PEROXIDE;

CELLS;

BORONIC ACID DERIVATIVE; CHLORMETHINE; HYDROGEN PEROXIDE; POTASSIUM DIHYDROGEN PHOSPHATE; REACTIVE OXYGEN METABOLITE;

ARTICLE; CANCER CELL; CANCER INHIBITION; CHEMICAL STRUCTURE; CYTOTOXICITY; DNA ALKYLATION; DNA CLEAVAGE; DNA CROSS LINKING; DNA DAMAGE; POLYACRYLAMIDE GEL ELECTROPHORESIS;

ANTINEOPLASTIC AGENTS, ALKYLATING; CELL LINE, TUMOR; DNA; DRUG DESIGN; HUMANS; HYDROGEN PEROXIDE; INTERCALATING AGENTS; MECHLORETHAMINE; NEOPLASMS; PRODRUGS; REACTIVE OXYGEN SPECIES;

EID: 82555170608     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja2073824     Document Type: Article

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