Gemcitabine-coumarin-biotin conjugates: A target specific theranostic anticancer prodrug

Journal of the American Chemical Society

Volumn 135, Issue 11, 2013, Pages 4567-4572

  Maiti, Sukhendu ^a   Park, Nayoung ^a   Han, Ji Hye ^b   Jeon, Hyun Mi ^b   Lee, Jae Hong ^a   Bhuniya, Sankarprasad ^a   Kang, Chulhun ^b   Kim, Jong Seung ^a  

^a Korea University   (South Korea)

^b Kyung Hee University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ASSESSMENT; CO-LOCALIZATION STUDIES; DISULFIDE BOND CLEAVAGES; FLUORESCENCE INTENSITIES; MULTI-FUNCTIONAL MOLECULES; RECEPTOR-MEDIATED ENDOCYTOSIS; SPECTROSCOPIC CHARACTERIZATION; TWO-PHOTON FLUORESCENCE IMAGING;

CELL MEMBRANES; COENZYMES; COVALENT BONDS; DRUG DELIVERY; FLUORESCENCE; MOLECULAR BIOLOGY;

DRUG PRODUCTS;

BIOTIN; COUMARIN; GEMCITABINE; PRODRUG; THIOL DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONFOCAL MICROSCOPY; DISULFIDE BOND; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SYNTHESIS; DRUG UPTAKE; ENDOCYTOSIS; FLUORESCENCE SPECTROSCOPY; IN VITRO STUDY; LYSOSOME; REACTION ANALYSIS; THERANOSTIC DRUG DELIVERY SYSTEM; THERAPY EFFECT; TUMOR CELL;

ANTINEOPLASTIC AGENTS; BIOTIN; CELL LINE, TUMOR; CELL SURVIVAL; COUMARINS; DEOXYCYTIDINE; DRUG DELIVERY SYSTEMS; FLUORESCENT DYES; HUMANS; NEOPLASMS; PRODRUGS; SULFHYDRYL COMPOUNDS;

EID: 84875480413     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja401350x     Document Type: Article

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