메뉴 건너뛰기




Volumn 37, Issue 8, 2014, Pages 729-737

Altered expression of 3-betahydroxysterol delta-24-reductase/selective Alzheimer's disease indicator-1 gene in Huntington's disease models

Author keywords

Cholesterol; DHCR24; Huntingtin; Neurodegeneration; Oxidative stress; Seladin 1

Indexed keywords

3 BETAHYDROXYSTEROL DELTA-24 REDUCTASE; HUNTINGTIN; OXIDOREDUCTASE; POLYGLUTAMINE; UNCLASSIFIED DRUG; 3BETA-HYDROXYSTEROL DELTA24-REDUCTASE; DHCR24 PROTEIN, HUMAN; DHCR24 PROTEIN, MOUSE; HTT PROTEIN, HUMAN; MESSENGER RNA; NERVE PROTEIN; RECOMBINANT PROTEIN;

EID: 84907367953     PISSN: 03914097     EISSN: 17208386     Source Type: Journal    
DOI: 10.1007/s40618-014-0098-1     Document Type: Article
Times cited : (6)

References (47)
  • 2
    • 0345255889 scopus 로고    scopus 로고
    • Human malformation syndromes due to inborn errors of cholesterol synthesis
    • Porter FD (2003) Human malformation syndromes due to inborn errors of cholesterol synthesis. Curr Opin Pediatr 15:607-613
    • (2003) Curr Opin Pediatr , vol.15 , pp. 607-613
    • Porter, F.D.1
  • 3
    • 0034307463 scopus 로고    scopus 로고
    • The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to Alzheimer's disease-associated neurodegeneration and oxidative stress
    • Greeve I, Hermans-Borgmeyer I, Brellinger C et al (2000) The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to Alzheimer's disease-associated neurodegeneration and oxidative stress. J Neurosci 20:7345-7352
    • (2000) J Neurosci , vol.20 , pp. 7345-7352
    • Greeve, I.1    Hermans-Borgmeyer, I.2    Brellinger, C.3
  • 5
    • 50949111281 scopus 로고    scopus 로고
    • Seladin-1/DHCR24 protects neuroblastoma cells against Abeta toxicity by increasing membrane cholesterol content
    • Cecchi C, Rosati F, Pensalfini A et al (2008) Seladin-1/DHCR24 protects neuroblastoma cells against Abeta toxicity by increasing membrane cholesterol content. J Cell Mol Med 12:1990-2002
    • (2008) J Cell Mol Med , vol.12 , pp. 1990-2002
    • Cecchi, C.1    Rosati, F.2    Pensalfini, A.3
  • 6
    • 37849018203 scopus 로고    scopus 로고
    • Prosurvival effect of DHCR24/Seladin-1 in acute and chronic responses to oxidative stress
    • Kuehnle K, Crameri A, Kälin R et al (2008) Prosurvival effect of DHCR24/Seladin-1 in acute and chronic responses to oxidative stress. Mol Cell Biol 28:539-550
    • (2008) Mol Cell Biol , vol.28 , pp. 539-550
    • Kuehnle, K.1    Crameri, A.2    Kälin, R.3
  • 7
    • 57749083174 scopus 로고    scopus 로고
    • Neuroprotective effects of the Alzheimer's disease-related gene seladin-1
    • Peri A, Serio M (2008) Neuroprotective effects of the Alzheimer's disease-related gene seladin-1. J Mol Endocrinol 41:251-261
    • (2008) J Mol Endocrinol , vol.41 , pp. 251-261
    • Peri, A.1    Serio, M.2
  • 8
    • 46349096632 scopus 로고    scopus 로고
    • 3beta-hydroxysteroid-delta24 reductase is a hydrogen peroxide scavenger, protecting cells from oxidative stress-induced apoptosis
    • DOI 10.1210/en.2008-0024
    • Lu X, Kambe F, Cao X et al (2008) 3beta-Hydroxysteroiddelta24 reductase is a hydrogen peroxide scavenger, protecting cells from oxidative stress-induced apoptosis. Endocrinology 149:3267-3273 (Pubitemid 351919585)
    • (2008) Endocrinology , vol.149 , Issue.7 , pp. 3267-3273
    • Lu, X.1    Kambe, F.2    Cao, X.3    Kozaki, Y.4    Kaji, T.5    Ishii, T.6    Seo, H.7
  • 9
    • 80052269266 scopus 로고    scopus 로고
    • Membrane cholesterol as a mediator of the neuroprotective effects of estrogens
    • Peri A, Benvenuti S, Luciani P, Deledda C, Cellai I (2011) Membrane cholesterol as a mediator of the neuroprotective effects of estrogens. Neuroscience 191:107-117
    • (2011) Neuroscience , vol.191 , pp. 107-117
    • Peri, A.1    Benvenuti, S.2    Luciani, P.3    Deledda, C.4    Cellai, I.5
  • 10
    • 80051797370 scopus 로고    scopus 로고
    • Protective action of neurotrophic factors and estrogen against oxidative stress-mediated neurodegeneration
    • Numakawa T, Matsumoto T, Numakawa Y, Richards M, Yamawaki S, Kunugi H (2011) Protective action of neurotrophic factors and estrogen against oxidative stress-mediated neurodegeneration. J Toxicol 2011:405194
    • (2011) J Toxicol , vol.2011 , pp. 405194
    • Numakawa, T.1    Matsumoto, T.2    Numakawa, Y.3    Richards, M.4    Yamawaki, S.5    Kunugi, H.6
  • 12
    • 0027480960 scopus 로고
    • A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • The Huntington Disease Collaborative Research G
    • The Huntington Disease Collaborative Research (1993) G. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 72:971-983
    • (1993) Cell , vol.72 , pp. 971-983
  • 14
    • 0035805504 scopus 로고    scopus 로고
    • Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing
    • Rigamonti D, Sipione S, Goffredo D, Zuccato C, Fossale E, Cattaneo E (2001) Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing. J Biol Chem 276:14545-14548
    • (2001) J Biol Chem , vol.276 , pp. 14545-14548
    • Rigamonti, D.1    Sipione, S.2    Goffredo, D.3    Zuccato, C.4    Fossale, E.5    Cattaneo, E.6
  • 15
    • 77955643169 scopus 로고    scopus 로고
    • Molecular mechanisms and potential therapeutical targets in Huntington's disease
    • Zuccato C, Valenza M, Cattaneo E (2010) Molecular mechanisms and potential therapeutical targets in Huntington's disease. Physiol Rev 90:905-981
    • (2010) Physiol Rev , vol.90 , pp. 905-981
    • Zuccato, C.1    Valenza, M.2    Cattaneo, E.3
  • 16
    • 63449102847 scopus 로고    scopus 로고
    • Neuroendocrine disturbances in Huntington's disease
    • Saleh N, Moutereau S, Durr A et al (2009) Neuroendocrine disturbances in Huntington's disease. PLoS One 4:e4962
    • (2009) PLoS One , vol.4
    • Saleh, N.1    Moutereau, S.2    Durr, A.3
  • 17
    • 33747602312 scopus 로고    scopus 로고
    • Hypothalamic-endocrine aspects in Huntington's disease
    • Petersén A, Björkqvist M (2006) Hypothalamic-endocrine aspects in Huntington's disease. Eur J Neurosci 24:961-967
    • (2006) Eur J Neurosci , vol.24 , pp. 961-967
    • Petersén, A.1    Björkqvist, M.2
  • 18
    • 33947675275 scopus 로고    scopus 로고
    • Oxidative damage in Huntington's disease pathogenesis
    • Browne SE, Beal MF (2006) Oxidative damage in Huntington's disease pathogenesis. Antioxid Redox Signal 8:2061-2073 (Pubitemid 46489631)
    • (2006) Antioxidants and Redox Signaling , vol.8 , Issue.11-12 , pp. 2061-2073
    • Browne, S.E.1    Beal, M.F.2
  • 19
    • 0035282594 scopus 로고    scopus 로고
    • Loss of normal huntingtin function: New developments in Huntington's disease research
    • DOI 10.1016/S0166-2236(00)01721-5, PII S0166223600017215
    • Cattaneo E, Rigamonti D, Goffredo D, Zuccato C, Squitieri F, Sipione S (2001) Loss of normal huntingtin function: new developments in Huntington's disease research. Trends Neurosci 24:182-188 (Pubitemid 32166824)
    • (2001) Trends in Neurosciences , vol.24 , Issue.3 , pp. 182-188
    • Cattaneo, E.1    Rigamonti, D.2    Goffredo, D.3    Zuccato, C.4    Squitieri, F.5    Sipione, S.6
  • 21
    • 34548777515 scopus 로고    scopus 로고
    • Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease
    • DOI 10.1016/j.nbd.2007.07.004, PII S096999610700143X
    • Valenza M, Leoni V, Tarditi A et al (2007) Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease. Neurobiol Dis 28:133-142 (Pubitemid 47429978)
    • (2007) Neurobiology of Disease , vol.28 , Issue.1 , pp. 133-142
    • Valenza, M.1    Leoni, V.2    Tarditi, A.3    Mariotti, C.4    Bjorkhem, I.5    Di, D.S.6    Cattaneo, E.7
  • 22
    • 77956216040 scopus 로고    scopus 로고
    • Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes
    • Valenza M, Leoni V, Karasinska JM et al (2010) Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes. J Neurosci 30:10844-10850
    • (2010) J Neurosci , vol.30 , pp. 10844-10850
    • Valenza, M.1    Leoni, V.2    Karasinska, J.M.3
  • 23
    • 79954420690 scopus 로고    scopus 로고
    • Whole body cholesterol metabolism is impaired in Huntington's disease
    • Leoni V, Mariotti C, Nanetti L et al (2011) Whole body cholesterol metabolism is impaired in Huntington's disease. Neurosci Lett 494:245-249
    • (2011) Neurosci Lett , vol.494 , pp. 245-249
    • Leoni, V.1    Mariotti, C.2    Nanetti, L.3
  • 25
    • 55749085638 scopus 로고    scopus 로고
    • Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease
    • Leoni V, Mariotti C, Tabrizi SJ et al (2008) Plasma 24S- hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease. Brain 131:2851-2859
    • (2008) Brain , vol.131 , pp. 2851-2859
    • Leoni, V.1    Mariotti, C.2    Tabrizi, S.J.3
  • 26
    • 66449104770 scopus 로고    scopus 로고
    • Regulator of calcineurin (RCAN1-1L) is deficient in Huntington disease and protective against mutant huntingtin toxicity in vitro
    • Ermak G, Hench KJ, Chang KT, Sachdev S, Davies KJ (2009) Regulator of calcineurin (RCAN1-1L) is deficient in Huntington disease and protective against mutant huntingtin toxicity in vitro. J Biol Chem 284:11845-11853
    • (2009) J Biol Chem , vol.284 , pp. 11845-11853
    • Ermak, G.1    Hench, K.J.2    Chang, K.T.3    Sachdev, S.4    Davies, K.J.5
  • 29
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29:e45
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 30
    • 0030752709 scopus 로고    scopus 로고
    • Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
    • DOI 10.1126/science.277.5334.1990
    • DiFiglia M, Sapp E, Chase KO et al (1997) Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain. Science 277:1990-1993 (Pubitemid 27449140)
    • (1997) Science , vol.277 , Issue.5334 , pp. 1990-1993
    • DiFiglia, M.1    Sapp, E.2    Chase, K.O.3    Davies, S.W.4    Bates, G.P.5    Vonsattel, J.P.6    Aronin, N.7
  • 32
    • 84873376098 scopus 로고    scopus 로고
    • Evaluation of histone deacetylases as drug targets in Huntington's disease models. Study of HDACs in brain tissues from R6/2 and CAG140 knockin HD mouse models and human patients and in a neuronal HD cell model
    • doi:10.1371/currents.RRN1172
    • Quinti L, Chopra V, Rotili D, et al. (2010) Evaluation of histone deacetylases as drug targets in Huntington's disease models. Study of HDACs in brain tissues from R6/2 and CAG140 knockin HD mouse models and human patients and in a neuronal HD cell model. PLoS Curr 2. doi:10.1371/currents.RRN1172
    • (2010) PLoS Curr , vol.2
    • Quinti, L.1    Chopra, V.2    Rotili, D.3
  • 36
    • 84900859585 scopus 로고    scopus 로고
    • Multifaceted roles of BDNF and FGF2 in human striatal primordium development. An in vitro study
    • Sarchielli E, Marini M, Ambrosini S, et al. (2014) Multifaceted roles of BDNF and FGF2 in human striatal primordium development. An in vitro study. Exp Neurol 257C:130-147
    • (2014) Exp Neurol , vol.257 C , pp. 130-147
    • Sarchielli, E.1    Marini, M.2    Ambrosini, S.3
  • 37
    • 61949195032 scopus 로고    scopus 로고
    • Getting a handle on Huntington's disease: The case for cholesterol
    • Katsuno M, Adachi H, Sobue G (2009) Getting a handle on Huntington's disease: the case for cholesterol. Nat Med 15:253-254
    • (2009) Nat Med , vol.15 , pp. 253-254
    • Katsuno, M.1    Adachi, H.2    Sobue, G.3
  • 38
    • 10344229445 scopus 로고    scopus 로고
    • Regulation of cellular response to oncogenic and oxidative stress by Seladin-1
    • DOI 10.1038/nature03173
    • Wu C, Miloslavskaya I, Demontis S, Maestro R, Galaktionov K (2004) Regulation of cellular response to oncogenic and oxidative stress by Seladin-1. Nature 432:640-645 (Pubitemid 39626272)
    • (2004) Nature , vol.432 , Issue.7017 , pp. 640-645
    • Wu, C.1    Miloslavskaya, I.2    Demontis, S.3    Maestro, R.4    Galaktionov, K.5
  • 39
    • 66349086768 scopus 로고    scopus 로고
    • Role of 3beta-hydroxysteroid-delta 24 reductase in mediating antiinflammatory effects of high-density lipoproteins in endothelial cells
    • McGrath K, Li X, Puranik R et al (2009) Role of 3beta-hydroxysteroid- delta 24 reductase in mediating antiinflammatory effects of high-density lipoproteins in endothelial cells. Arterioscler Thromb Vasc Biol 29:877-882
    • (2009) Arterioscler Thromb Vasc Biol , vol.29 , pp. 877-882
    • McGrath, K.1    Li, X.2    Puranik, R.3
  • 42
    • 84865592653 scopus 로고    scopus 로고
    • Quantitative proteomic analysis of induced pluripotent stem cells derived from a human Huntington's disease patient
    • Chae JI, Kim DW, Lee N et al (2012) Quantitative proteomic analysis of induced pluripotent stem cells derived from a human Huntington's disease patient. Biochem J 446:359-371
    • (2012) Biochem J , vol.446 , pp. 359-371
    • Chae, J.I.1    Kim, D.W.2    Lee, N.3
  • 43
    • 80054883676 scopus 로고    scopus 로고
    • Modifications of p53 and the DNA damage response in cells expressing mutant form of the protein huntingtin
    • Illuzzi JL, Vickers CA, Kmiec EB (2011) Modifications of p53 and the DNA damage response in cells expressing mutant form of the protein huntingtin. J Mol Neurosci 45:256-268
    • (2011) J Mol Neurosci , vol.45 , pp. 256-268
    • Illuzzi, J.L.1    Vickers, C.A.2    Kmiec, E.B.3
  • 45
    • 0027741301 scopus 로고
    • Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy
    • Jenkins BG, Koroshetz WJ, Beal MF, Rosen BR (1993) Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy. Neurology 43:2689-2695 (Pubitemid 24004570)
    • (1993) Neurology , vol.43 , Issue.12 I , pp. 2689-2695
    • Jenkins, B.G.1    Koroshetz, W.J.2    Beal, M.F.3    Rosen, B.R.4
  • 46
    • 0032498817 scopus 로고    scopus 로고
    • Neuronal and glial somal size in the prefrontal cortex: A postmortem morphometric study of schizophrenia and Huntington disease
    • Rajkowska G, Selemon LD, Goldman-Rakic PS (1998) Neuronal and glial somal size in the prefrontal cortex: a postmortem morphometric study of schizophrenia and Huntington disease. Arch Gen Psychiatry 55:215-224
    • (1998) Arch Gen Psychiatry , vol.55 , pp. 215-224
    • Rajkowska, G.1    Selemon, L.D.2    Goldman-Rakic, P.S.3
  • 47
    • 61849180931 scopus 로고    scopus 로고
    • Marked differences in cholesterol synthesis between neurons and glial cells from postnatal rats
    • Nieweg K, Schaller H, Pfrieger FW (2009) Marked differences in cholesterol synthesis between neurons and glial cells from postnatal rats. J Neurochem 109:125-134
    • (2009) J Neurochem , vol.109 , pp. 125-134
    • Nieweg, K.1    Schaller, H.2    Pfrieger, F.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.