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Volumn 191, Issue , 2011, Pages 107-117

Membrane cholesterol as a mediator of the neuroprotective effects of estrogens

Author keywords

Alzheimer's disease; Cholesterol; Estrogens; IGF 1; Neurodegeneration; Seladin 1

Indexed keywords

3 BETA HYDROXYSTEROL DELTA 24 REDUCTASE; AMYLOID BETA PROTEIN; CHOLESTEROL; DESMOSTEROL; ESTRADIOL; ESTROGEN; RALOXIFENE; SOMATOMEDIN C; STEROID REDUCTASE; TAMOXIFEN; UNCLASSIFIED DRUG;

EID: 80052269266     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2011.03.011     Document Type: Review
Times cited : (26)

References (83)
  • 2
    • 40749118066 scopus 로고    scopus 로고
    • Estrogen genomic and membrane actions at an intersection
    • Arbogast L.A. Estrogen genomic and membrane actions at an intersection. Trends Endocrinol Metab 2008, 19:1-2.
    • (2008) Trends Endocrinol Metab , vol.19 , pp. 1-2
    • Arbogast, L.A.1
  • 3
    • 0036793543 scopus 로고    scopus 로고
    • Plasma membrane cholesterol controls the cytotoxicity of Alzheimer's disease AbetaP (1-40) and (1-42) peptides
    • Arispe N., Doh M. Plasma membrane cholesterol controls the cytotoxicity of Alzheimer's disease AbetaP (1-40) and (1-42) peptides. FASEB J 2002, 16:1526-1536.
    • (2002) FASEB J , vol.16 , pp. 1526-1536
    • Arispe, N.1    Doh, M.2
  • 5
    • 33947401545 scopus 로고    scopus 로고
    • Seladin-1 expression in rat adrenal gland: effect of adrenocorticotropic hormone treatment
    • Battista M.C., Roberge C., Otis M., Gallo-Payet N. Seladin-1 expression in rat adrenal gland: effect of adrenocorticotropic hormone treatment. J Endocrinol 2007, 192:53-66.
    • (2007) J Endocrinol , vol.192 , pp. 53-66
    • Battista, M.C.1    Roberge, C.2    Otis, M.3    Gallo-Payet, N.4
  • 6
    • 0032448780 scopus 로고    scopus 로고
    • Neurosteroids: a novel function of the brain
    • Baulieu E.E. Neurosteroids: a novel function of the brain. Psychoneuroendocrinology 1998, 23:963-987.
    • (1998) Psychoneuroendocrinology , vol.23 , pp. 963-987
    • Baulieu, E.E.1
  • 7
    • 0038657688 scopus 로고    scopus 로고
    • Estrogen can protect neurons: modes of action
    • Behl C. Estrogen can protect neurons: modes of action. J Steroid Biochem Mol Biol 2003, 83:195-197.
    • (2003) J Steroid Biochem Mol Biol , vol.83 , pp. 195-197
    • Behl, C.1
  • 8
    • 34147192546 scopus 로고    scopus 로고
    • Neurosteroids: endogenous modulators of neuronal excitability and plasticity
    • Benarroch E.E. Neurosteroids: endogenous modulators of neuronal excitability and plasticity. Neurology 2007, 68:945-947.
    • (2007) Neurology , vol.68 , pp. 945-947
    • Benarroch, E.E.1
  • 9
    • 15944411013 scopus 로고    scopus 로고
    • Estrogen and SERMs exert neuroprotective effects and stimulate the expression of seladin-1, a recently discovered anti-apoptotic gene, in human neuroblast long-term cell cultures
    • Benvenuti S., Luciani P., Vannelli G.B., Gelmini S., Franceschi E., Serio M., Peri A. Estrogen and SERMs exert neuroprotective effects and stimulate the expression of seladin-1, a recently discovered anti-apoptotic gene, in human neuroblast long-term cell cultures. J Clin Endocrinol Metab 2005, 90:1775-1782.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1775-1782
    • Benvenuti, S.1    Luciani, P.2    Vannelli, G.B.3    Gelmini, S.4    Franceschi, E.5    Serio, M.6    Peri, A.7
  • 11
    • 2442557294 scopus 로고    scopus 로고
    • Brain cholesterol: long secret life behind a barrier
    • Björkhem I., Meaney S. Brain cholesterol: long secret life behind a barrier. Arterioscler Thromb Vasc Biol 2004, 24:806-815.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 806-815
    • Björkhem, I.1    Meaney, S.2
  • 16
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to cell-intrinsic machinery
    • Datta S.R., Dudek H., Tao X., Masters S., Fu H., Gotoh Y., Greenberg M.E. Akt phosphorylation of BAD couples survival signals to cell-intrinsic machinery. Cell 1997, 91:231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 17
    • 1842333237 scopus 로고    scopus 로고
    • Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt
    • Del Peso L., González-García M., Page C., Herrera R., Nuñez G. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. Science 1997, 278:687-689.
    • (1997) Science , vol.278 , pp. 687-689
    • Del Peso, L.1    González-García, M.2    Page, C.3    Herrera, R.4    Nuñez, G.5
  • 18
    • 0036838768 scopus 로고    scopus 로고
    • Protective effects of estrogen and selective estrogen receptor modulators in the brain
    • Dhandapani K.M., Brann D.W. Protective effects of estrogen and selective estrogen receptor modulators in the brain. Biol Reprod 2002, 67:1379-1385.
    • (2002) Biol Reprod , vol.67 , pp. 1379-1385
    • Dhandapani, K.M.1    Brann, D.W.2
  • 20
    • 23144438782 scopus 로고    scopus 로고
    • DHCR24-knockout embryonic fibroblasts are susceptible to serum withdrawal-induced apoptosis because of dysfunction of caveolae and insulin-Akt-Bad signaling
    • Dong Y., Zhang H., Gao A.C., Marshall J.R., Ip C. DHCR24-knockout embryonic fibroblasts are susceptible to serum withdrawal-induced apoptosis because of dysfunction of caveolae and insulin-Akt-Bad signaling. Mol Cancer Ther 2005, 4:1047-1055.
    • (2005) Mol Cancer Ther , vol.4 , pp. 1047-1055
    • Dong, Y.1    Zhang, H.2    Gao, A.C.3    Marshall, J.R.4    Ip, C.5
  • 22
    • 67349113118 scopus 로고    scopus 로고
    • Cholesterol-promoted synaptogenesis requires the conversion of cholesterol to estradiol in the hippocampus
    • Fester L., Zhou L., Bütow A., Huber C., von Lossow R., Prabge-Kiel J., Jarry H., Rune G.M. Cholesterol-promoted synaptogenesis requires the conversion of cholesterol to estradiol in the hippocampus. Hippocampus 2009, 19:692-705.
    • (2009) Hippocampus , vol.19 , pp. 692-705
    • Fester, L.1    Zhou, L.2    Bütow, A.3    Huber, C.4    von Lossow, R.5    Prabge-Kiel, J.6    Jarry, H.7    Rune, G.M.8
  • 23
    • 0037163491 scopus 로고    scopus 로고
    • The role of hormone replacement therapy in the prevention of Alzheimer's disease
    • Fillit H.M. The role of hormone replacement therapy in the prevention of Alzheimer's disease. Arch Intern Med 2002, 162:1934-1942.
    • (2002) Arch Intern Med , vol.162 , pp. 1934-1942
    • Fillit, H.M.1
  • 25
    • 0001392322 scopus 로고    scopus 로고
    • AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor
    • Font de Mora J., Brown M. AIB1 is a conduit for kinase-mediated growth factor signaling to the estrogen receptor. Mol Cell Biol 2000, 20:5041-5047.
    • (2000) Mol Cell Biol , vol.20 , pp. 5041-5047
    • Font de Mora, J.1    Brown, M.2
  • 26
    • 0036773551 scopus 로고    scopus 로고
    • Growth hormone (GH) and GH-releasing peptide-6 increase brain insulin-like growth factor-I expression and activate intracellular signaling pathways involved in neuroprotection
    • Frago L.M., Pañeda C., Dickson S.L., Hewson A.K., Argente J., Chowen J.A. Growth hormone (GH) and GH-releasing peptide-6 increase brain insulin-like growth factor-I expression and activate intracellular signaling pathways involved in neuroprotection. Endocrinology 2002, 143:4113-4122.
    • (2002) Endocrinology , vol.143 , pp. 4113-4122
    • Frago, L.M.1    Pañeda, C.2    Dickson, S.L.3    Hewson, A.K.4    Argente, J.5    Chowen, J.A.6
  • 27
    • 22044443304 scopus 로고    scopus 로고
    • Seladin-1/DHCR24 expression in normal ovary, ovarian epithelial and granulosa tumours
    • Fuller P.J., Alexiadis M., Jobling T., McNeilage J. Seladin-1/DHCR24 expression in normal ovary, ovarian epithelial and granulosa tumours. Clin Endocrinol (Oxf) 2005, 63:111-115.
    • (2005) Clin Endocrinol (Oxf) , vol.63 , pp. 111-115
    • Fuller, P.J.1    Alexiadis, M.2    Jobling, T.3    McNeilage, J.4
  • 28
    • 77955496323 scopus 로고    scopus 로고
    • Interactions of estradiol and insulin-like growth factor-I signalling in the nervous system: new advances
    • Garcia-Segura L.M., Arévalo M.A., Azcoitia I. Interactions of estradiol and insulin-like growth factor-I signalling in the nervous system: new advances. Prog Brain Res 2010, 181:251-272.
    • (2010) Prog Brain Res , vol.181 , pp. 251-272
    • Garcia-Segura, L.M.1    Arévalo, M.A.2    Azcoitia, I.3
  • 30
    • 0034307463 scopus 로고    scopus 로고
    • The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to Alzheimer's disease-associated neurodegeneration and oxidative stress
    • Greeve I., Hermans-Borgmeyer I., Brellinger C., Kasper D., Gomez-Isla T., Behl C., Levkau B., Nitsch R.M. The human DIMINUTO/DWARF1 homolog seladin-1 confers resistance to Alzheimer's disease-associated neurodegeneration and oxidative stress. J Neurosci 2000, 20:7345-7352.
    • (2000) J Neurosci , vol.20 , pp. 7345-7352
    • Greeve, I.1    Hermans-Borgmeyer, I.2    Brellinger, C.3    Kasper, D.4    Gomez-Isla, T.5    Behl, C.6    Levkau, B.7    Nitsch, R.M.8
  • 31
    • 0034718549 scopus 로고    scopus 로고
    • Identification of a third distinct estrogen receptor and reclassification of estrogen receptors in teleosts
    • Hawkins M.B., Thornton J.W., Crews D., Skipper J.K., Dotte A., Thomas P. Identification of a third distinct estrogen receptor and reclassification of estrogen receptors in teleosts. Proc Natl Acad Sci U S A 2000, 97:10751-10756.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 10751-10756
    • Hawkins, M.B.1    Thornton, J.W.2    Crews, D.3    Skipper, J.K.4    Dotte, A.5    Thomas, P.6
  • 32
    • 34548846961 scopus 로고    scopus 로고
    • Alzheimer's disease and other neurological disorders
    • Henderson V.W. Alzheimer's disease and other neurological disorders. Climacteric 2007, 10(Suppl 2):92-96.
    • (2007) Climacteric , vol.10 , Issue.SUPPL 2 , pp. 92-96
    • Henderson, V.W.1
  • 34
    • 0037387601 scopus 로고    scopus 로고
    • Disorders of cholesterol biosynthesis: prototypic metabolic malformation syndromes
    • Spec No 1
    • Herman G.E. Disorders of cholesterol biosynthesis: prototypic metabolic malformation syndromes. Hum Mol Genet 2003, 12(Spec No 1):R75-R88.
    • (2003) Hum Mol Genet , vol.12
    • Herman, G.E.1
  • 35
    • 0042473074 scopus 로고    scopus 로고
    • Decreased estrogen receptor-α expression in hippocampal neurons in relation to hyperphosphorylated tau in Alzheimer patients
    • Hu X.Y., Qin S., Lu Y.P., Ravid R., Swaab D.F., Zhou J.N. Decreased estrogen receptor-α expression in hippocampal neurons in relation to hyperphosphorylated tau in Alzheimer patients. Acta Neuropathol 2003, 106:213-220.
    • (2003) Acta Neuropathol , vol.106 , pp. 213-220
    • Hu, X.Y.1    Qin, S.2    Lu, Y.P.3    Ravid, R.4    Swaab, D.F.5    Zhou, J.N.6
  • 37
    • 10344226187 scopus 로고    scopus 로고
    • A lipid boundary separates APP and secretases and limits amyloid beta-peptide generation
    • Kaether C., Haass C. A lipid boundary separates APP and secretases and limits amyloid beta-peptide generation. J Cell Biol 2004, 167:809-812.
    • (2004) J Cell Biol , vol.167 , pp. 809-812
    • Kaether, C.1    Haass, C.2
  • 40
    • 46349096632 scopus 로고    scopus 로고
    • DHCR24 is a hydrogen peroxide scavenger, protecting cells from oxidative-stress-induced apoptosis
    • Lu X., Kambe F., Cao X., Kozaki Y., Kaji T., Ishii T., Seo H. DHCR24 is a hydrogen peroxide scavenger, protecting cells from oxidative-stress-induced apoptosis. Endocrinology 2008, 149:3267-3273.
    • (2008) Endocrinology , vol.149 , pp. 3267-3273
    • Lu, X.1    Kambe, F.2    Cao, X.3    Kozaki, Y.4    Kaji, T.5    Ishii, T.6    Seo, H.7
  • 44
    • 0028364282 scopus 로고
    • Insulin-like growth factors activate estrogen receptor to control the growth and differentiation of the human neuroblastoma cell line SK-ER3
    • Ma Z.Q., Santagati S., Patrone C., Pollio G., Vegeto E., Maggi A. Insulin-like growth factors activate estrogen receptor to control the growth and differentiation of the human neuroblastoma cell line SK-ER3. Mol Endocrinol 1994, 8:910-918.
    • (1994) Mol Endocrinol , vol.8 , pp. 910-918
    • Ma, Z.Q.1    Santagati, S.2    Patrone, C.3    Pollio, G.4    Vegeto, E.5    Maggi, A.6
  • 45
    • 3042541852 scopus 로고    scopus 로고
    • Estrogen and Alzheimer's disease: the apolipoprotein connection
    • MacLusky N.J. Estrogen and Alzheimer's disease: the apolipoprotein connection. Endocrinology 2004, 145:3062-3064.
    • (2004) Endocrinology , vol.145 , pp. 3062-3064
    • MacLusky, N.J.1
  • 46
    • 2342582858 scopus 로고    scopus 로고
    • Estrogens in the nervous system: mechanisms and nonreproductive functions
    • Maggi A., Ciana P., Belcredito S., Vegeto E. Estrogens in the nervous system: mechanisms and nonreproductive functions. Annu Rev Physiol 2004, 66:291-313.
    • (2004) Annu Rev Physiol , vol.66 , pp. 291-313
    • Maggi, A.1    Ciana, P.2    Belcredito, S.3    Vegeto, E.4
  • 47
    • 84856069012 scopus 로고    scopus 로고
    • Estradiol prevents amyloid-beta peptide-induced cell death in a cholinergic cell line via modulation of a classical estrogen receptor
    • Marin R., Guerra B., Hernández-Jiménez J.G., Kang X.L., Fraser J.D., Lopez F.J., Alonso R. Estradiol prevents amyloid-beta peptide-induced cell death in a cholinergic cell line via modulation of a classical estrogen receptor. Neuroscience 2009, 12:917-926.
    • (2009) Neuroscience , vol.12 , pp. 917-926
    • Marin, R.1    Guerra, B.2    Hernández-Jiménez, J.G.3    Kang, X.L.4    Fraser, J.D.5    Lopez, F.J.6    Alonso, R.7
  • 48
    • 0030052757 scopus 로고    scopus 로고
    • Insulin-like growth factor I rescues SH-SY5Y human neuroblastoma cells from hyperosmotic induced programmed cell death
    • Matthews C.C., Feldman E.L. Insulin-like growth factor I rescues SH-SY5Y human neuroblastoma cells from hyperosmotic induced programmed cell death. J Cell Physiol 1996, 166:323-331.
    • (1996) J Cell Physiol , vol.166 , pp. 323-331
    • Matthews, C.C.1    Feldman, E.L.2
  • 49
    • 17844399257 scopus 로고    scopus 로고
    • Interdependence of oestrogen and insulin-like growth factor-I in the brain: potential for analyzing neuroprotective mechanisms
    • Mendez P., Azcoitia I., Garcia-Segura L.M. Interdependence of oestrogen and insulin-like growth factor-I in the brain: potential for analyzing neuroprotective mechanisms. J Endocrinol 2005, 185:11-17.
    • (2005) J Endocrinol , vol.185 , pp. 11-17
    • Mendez, P.1    Azcoitia, I.2    Garcia-Segura, L.M.3
  • 50
    • 33646791491 scopus 로고    scopus 로고
    • Phosphatidylinositol 3 kinase (PI3K) and glycogen synthase kinase 3 (GSK3) regulate estrogen receptor-mediated transcription in neuronal cells
    • Mendez P., Garcia-Segura L.M. Phosphatidylinositol 3 kinase (PI3K) and glycogen synthase kinase 3 (GSK3) regulate estrogen receptor-mediated transcription in neuronal cells. Endocrinology 2006, 147:3027-3039.
    • (2006) Endocrinology , vol.147 , pp. 3027-3039
    • Mendez, P.1    Garcia-Segura, L.M.2
  • 51
    • 40949136507 scopus 로고    scopus 로고
    • Increased expression of aquaporin-3 in the epidermis of DHCR24 knockout mice
    • Mirza R., Hayasaka S., Kambe F., Maki K., Kaji T., Murata Y., Seo H. Increased expression of aquaporin-3 in the epidermis of DHCR24 knockout mice. Br J Dermatol 2008, 158:679-684.
    • (2008) Br J Dermatol , vol.158 , pp. 679-684
    • Mirza, R.1    Hayasaka, S.2    Kambe, F.3    Maki, K.4    Kaji, T.5    Murata, Y.6    Seo, H.7
  • 53
    • 33644916119 scopus 로고    scopus 로고
    • Cholesterol, LDL, and 25-hydroxycholesterol regulate expression of the steroidogenic acute regulatory protein in microvascular endothelial cell line (bEnd3)
    • Ning Y., Chen S., Li X., Ma Y., Zhao F., Yin L. Cholesterol, LDL, and 25-hydroxycholesterol regulate expression of the steroidogenic acute regulatory protein in microvascular endothelial cell line (bEnd3). Biochem Biophys Res Commun 2006, 342:1249-1256.
    • (2006) Biochem Biophys Res Commun , vol.342 , pp. 1249-1256
    • Ning, Y.1    Chen, S.2    Li, X.3    Ma, Y.4    Zhao, F.5    Yin, L.6
  • 54
    • 0347624528 scopus 로고    scopus 로고
    • Impact of the selective estrogen receptor modulator, raloxifene, on neuronal survival and outgrowth following toxic insults associated with aging and Alzheimer's disease
    • O'Neill K., Chen S., Brinton R.D. Impact of the selective estrogen receptor modulator, raloxifene, on neuronal survival and outgrowth following toxic insults associated with aging and Alzheimer's disease. Exp Neurol 2004, 185:63-80.
    • (2004) Exp Neurol , vol.185 , pp. 63-80
    • O'Neill, K.1    Chen, S.2    Brinton, R.D.3
  • 55
    • 3042751870 scopus 로고    scopus 로고
    • Impact of the selective estrogen receptor modulator, tamoxifen, on neuronal outgrowth and survival following toxic insults associated with aging and Alzheimer's disease
    • O'Neill K., Chen S., Brinton R.D. Impact of the selective estrogen receptor modulator, tamoxifen, on neuronal outgrowth and survival following toxic insults associated with aging and Alzheimer's disease. Exp Neurol 2004, 188:268-278.
    • (2004) Exp Neurol , vol.188 , pp. 268-278
    • O'Neill, K.1    Chen, S.2    Brinton, R.D.3
  • 56
    • 0028085516 scopus 로고
    • Estrogen deficiency and risk of Alzheimer's disease in women
    • Paganini-Hill V.W., Henderson V.W. Estrogen deficiency and risk of Alzheimer's disease in women. Am J Epidemiol 1994, 140:256-261.
    • (1994) Am J Epidemiol , vol.140 , pp. 256-261
    • Paganini-Hill, V.W.1    Henderson, V.W.2
  • 57
    • 14944378361 scopus 로고    scopus 로고
    • Phytoestrogen action in the adult and developing brain
    • Patisaul H.B. Phytoestrogen action in the adult and developing brain. J Neuroendocrinol 2005, 17:57-64.
    • (2005) J Neuroendocrinol , vol.17 , pp. 57-64
    • Patisaul, H.B.1
  • 58
    • 0032230260 scopus 로고    scopus 로고
    • Divergent pathways regulate ligand-independent activation of ER alpha in SK-N-BE neuroblastoma and COS-1 renal carcinoma cells
    • Patrone C., Gianazza E., Santagati S., Agrati P., Maggi A. Divergent pathways regulate ligand-independent activation of ER alpha in SK-N-BE neuroblastoma and COS-1 renal carcinoma cells. Mol Endocrinol 1998, 12:835-841.
    • (1998) Mol Endocrinol , vol.12 , pp. 835-841
    • Patrone, C.1    Gianazza, E.2    Santagati, S.3    Agrati, P.4    Maggi, A.5
  • 61
    • 0034711215 scopus 로고    scopus 로고
    • Lipoproteins regulate expression of the steroidogenic acute regulatory protein (StAR) in mouse adrenocortical cells
    • Reyland M.E., Evans R.M., White E.K. Lipoproteins regulate expression of the steroidogenic acute regulatory protein (StAR) in mouse adrenocortical cells. J Biol Chem 2000, 275:36637-36644.
    • (2000) J Biol Chem , vol.275 , pp. 36637-36644
    • Reyland, M.E.1    Evans, R.M.2    White, E.K.3
  • 62
    • 28844432459 scopus 로고    scopus 로고
    • The insulin-like growth factor system and its pleiotropic functions in brain
    • Russo V.C., Gluckman P.D., Feldman E.L., Werther G.A. The insulin-like growth factor system and its pleiotropic functions in brain. Endocr Rev 2005, 26:916-943.
    • (2005) Endocr Rev , vol.26 , pp. 916-943
    • Russo, V.C.1    Gluckman, P.D.2    Feldman, E.L.3    Werther, G.A.4
  • 63
    • 2142697164 scopus 로고    scopus 로고
    • Neuronal protection from glucose deprivation via modulation of glucose transport and inhibition of apoptosis: a role for the insulin-like growth factor system
    • Russo V.C., Kobayashi K., Najdovska S., Baker N.L., Werther G.A. Neuronal protection from glucose deprivation via modulation of glucose transport and inhibition of apoptosis: a role for the insulin-like growth factor system. Brain Res 2004, 1009:40-53.
    • (2004) Brain Res , vol.1009 , pp. 40-53
    • Russo, V.C.1    Kobayashi, K.2    Najdovska, S.3    Baker, N.L.4    Werther, G.A.5
  • 64
    • 0035176343 scopus 로고    scopus 로고
    • The human homolog of Diminuto/Dwarf1 gene (hDiminuto): a novel ACTH-responsive gene overexpressed in benign cortisol-producing adrenocortical adenomas
    • Sarkar D., Imai T., Kambe F., Shibata A., Ohmori S., Siddiq A., Hayasaka S., Funahashi H., Seo H. The human homolog of Diminuto/Dwarf1 gene (hDiminuto): a novel ACTH-responsive gene overexpressed in benign cortisol-producing adrenocortical adenomas. J Clin Endocrinol Metab 2001, 86:5130-5137.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5130-5137
    • Sarkar, D.1    Imai, T.2    Kambe, F.3    Shibata, A.4    Ohmori, S.5    Siddiq, A.6    Hayasaka, S.7    Funahashi, H.8    Seo, H.9
  • 66
    • 0035066332 scopus 로고    scopus 로고
    • Alzheimer's disease: genes, proteins, and therapy
    • Selkoe D.J. Alzheimer's disease: genes, proteins, and therapy. Physiol Rev 2001, 81:741-776.
    • (2001) Physiol Rev , vol.81 , pp. 741-776
    • Selkoe, D.J.1
  • 67
    • 0034791028 scopus 로고    scopus 로고
    • Soy isoflavones-benefits and risks from nature's selective estrogen receptor modulators (SERMs)
    • Setchell K.D. Soy isoflavones-benefits and risks from nature's selective estrogen receptor modulators (SERMs). J Am Coll Nutr 2001, 20:354S-362S.
    • (2001) J Am Coll Nutr , vol.20
    • Setchell, K.D.1
  • 69
    • 1442323686 scopus 로고    scopus 로고
    • Minireview: a plethora of estrogen receptors in the brain: where will it end?
    • Toran-Allerand C.D. Minireview: a plethora of estrogen receptors in the brain: where will it end?. Endocrinology 2004, 145:1069-1074.
    • (2004) Endocrinology , vol.145 , pp. 1069-1074
    • Toran-Allerand, C.D.1
  • 70
    • 33750042898 scopus 로고    scopus 로고
    • Complex actions of sex steroids in adipose tissue, the cardiovascular system, and brain: insights from basic science and clinical studies
    • Turgeon J.L., Carr M.C., Maki P.M., Mendelsohn M.E., Wise P. Complex actions of sex steroids in adipose tissue, the cardiovascular system, and brain: insights from basic science and clinical studies. Endocr Rev 2006, 27:576-605.
    • (2006) Endocr Rev , vol.27 , pp. 576-605
    • Turgeon, J.L.1    Carr, M.C.2    Maki, P.M.3    Mendelsohn, M.E.4    Wise, P.5
  • 72
    • 33846862008 scopus 로고    scopus 로고
    • Membrane-initiated actions of estrogens in neuroendocrinology: emerging principles
    • Vasudeven N., Pfaff D.W. Membrane-initiated actions of estrogens in neuroendocrinology: emerging principles. Endocr Rev 2008, 28:1-19.
    • (2008) Endocr Rev , vol.28 , pp. 1-19
    • Vasudeven, N.1    Pfaff, D.W.2
  • 74
    • 0035956960 scopus 로고    scopus 로고
    • Morphological abnormalities in the brains of estrogen receptor beta knockout mice
    • Wang L., Andersson S., Warner M., Gustafsson J.A. Morphological abnormalities in the brains of estrogen receptor beta knockout mice. Proc Natl Acad Sci U S A 2001, 98:2792-2796.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 2792-2796
    • Wang, L.1    Andersson, S.2    Warner, M.3    Gustafsson, J.A.4
  • 77
    • 10344229445 scopus 로고    scopus 로고
    • Regulation of cellular response to oncogenic and oxidative stress by Seladin-1
    • Wu C., Miloslavskaya I., Demontis S., Maestro R., Galaktionov K. Regulation of cellular response to oncogenic and oxidative stress by Seladin-1. Nature 2002, 432:640-645.
    • (2002) Nature , vol.432 , pp. 640-645
    • Wu, C.1    Miloslavskaya, I.2    Demontis, S.3    Maestro, R.4    Galaktionov, K.5
  • 78
    • 16844368852 scopus 로고    scopus 로고
    • Effect of raloxifene on prevention of dementia and cognitive imparirment in older women: the Multiple Outcome of Raloxifene Evaluation (MORE) randomized trial
    • Yaffe K., Krueger K., Cummings S.R., Blackwell T., Henderson V.W., Sarkar S., Ensrud K., Grady D. Effect of raloxifene on prevention of dementia and cognitive imparirment in older women: the Multiple Outcome of Raloxifene Evaluation (MORE) randomized trial. Am J Psychiatry 2005, 162:683-690.
    • (2005) Am J Psychiatry , vol.162 , pp. 683-690
    • Yaffe, K.1    Krueger, K.2    Cummings, S.R.3    Blackwell, T.4    Henderson, V.W.5    Sarkar, S.6    Ensrud, K.7    Grady, D.8
  • 79
    • 0037010313 scopus 로고    scopus 로고
    • Cholesterol and pathological processes in Alzheimer's disease
    • Yanagisawa K. Cholesterol and pathological processes in Alzheimer's disease. J Neurosci Res 2002, 70:361-366.
    • (2002) J Neurosci Res , vol.70 , pp. 361-366
    • Yanagisawa, K.1
  • 80
    • 58149465620 scopus 로고    scopus 로고
    • Reduced membrane lipids in the cortex of Alzheimer's disease transgenic mice
    • Yao J.K., Wengenack T.M., Curran G.L., Poduslo J.F. Reduced membrane lipids in the cortex of Alzheimer's disease transgenic mice. Neurochem Res 2009, 34:102-108.
    • (2009) Neurochem Res , vol.34 , pp. 102-108
    • Yao, J.K.1    Wengenack, T.M.2    Curran, G.L.3    Poduslo, J.F.4
  • 81
    • 0037032401 scopus 로고    scopus 로고
    • Cache County Memory Study Investigators, hormone replacement therapy and incidence of Alzheimer disease in older women
    • Zandi P.P., Carlson M.C., Plassman B.L., Welsh-Bohmer K.A., Mayer L.S., Steffens D.C., Breitner J.C. Cache County Memory Study Investigators, hormone replacement therapy and incidence of Alzheimer disease in older women. JAMA 2002, 288:2123-2129.
    • (2002) JAMA , vol.288 , pp. 2123-2129
    • Zandi, P.P.1    Carlson, M.C.2    Plassman, B.L.3    Welsh-Bohmer, K.A.4    Mayer, L.S.5    Steffens, D.C.6    Breitner, J.C.7
  • 82
    • 0037444650 scopus 로고    scopus 로고
    • Estrogen levels regulate the subcellular distribution of phosphorylated Akt in hippocampal CA1 dendrites
    • Znamensky V., Akama K.T., McEwen B.S., Milner T.A. Estrogen levels regulate the subcellular distribution of phosphorylated Akt in hippocampal CA1 dendrites. J Neurosci 2003, 23:2340-2347.
    • (2003) J Neurosci , vol.23 , pp. 2340-2347
    • Znamensky, V.1    Akama, K.T.2    McEwen, B.S.3    Milner, T.A.4
  • 83
    • 58149469232 scopus 로고    scopus 로고
    • The molecular mechanism of endoplasmic reticulum stress-induced apoptosis in PC-12 neuronal cells: the protective effect of insulin-like growth factor I
    • Zou C.G., Cao X.Z., Zhao Y.S., Gao S.Y., Li S.D., Liu X.Y., Zhang Y., Zhang K.Q. The molecular mechanism of endoplasmic reticulum stress-induced apoptosis in PC-12 neuronal cells: the protective effect of insulin-like growth factor I. Endocrinology 2009, 150:277-285.
    • (2009) Endocrinology , vol.150 , pp. 277-285
    • Zou, C.G.1    Cao, X.Z.2    Zhao, Y.S.3    Gao, S.Y.4    Li, S.D.5    Liu, X.Y.6    Zhang, Y.7    Zhang, K.Q.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.