Autophagic degradation of the inhibitory p53 isoform δ 133p53α as a regulatory mechanism for p53-mediated senescence

Nature Communications

Volumn 5, Issue , 2014, Pages

  Horikawa, Izumi ^a   Fujita, Kaori ^a   Jenkins, Lisa M Miller ^a   Hiyoshi, Yukiharu ^a   Mondal, Abdul M ^a   Vojtesek, Borivoj ^b   Lane, David P ^c,d   Appella, Ettore ^b   Harris, Curtis C ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b MASARYK MEMORIAL CANCER INSTITUTE   (Czech Republic)

^c INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 5; AUTOPHAGY PROTEIN 7; BECLIN 1; CELL PROTEIN; DELTA 133P53 ALPHA PROTEIN; PROTEIN P53; SMALL INTERFERING RNA; STUB1 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; ANDROSTANE DERIVATIVE; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, HUMAN; CYCLOHEXIMIDE; ISOPROTEIN; MAP1LC3B PROTEIN, HUMAN; MEMBRANE PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SQSTM1 PROTEIN, HUMAN; STUB1 PROTEIN, HUMAN; TP53 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE; WORTMANNIN;

GENE EXPRESSION; PROTEIN; RNA; SENESCENCE;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL AGING; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; FIBROBLAST; GENE SILENCING; HUMAN; HUMAN CELL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METABOLISM; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; CELL CULTURE; DRUG EFFECTS; GENETICS; METABOLISM; PHYSIOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANDROSTADIENES; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL AGING; CELLS, CULTURED; CYCLOHEXIMIDE; FIBROBLASTS; GENE KNOCKDOWN TECHNIQUES; HUMANS; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; PROTEIN ISOFORMS; RNA, SMALL INTERFERING; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN-PROTEIN LIGASES;

EID: 84907306512     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5706     Document Type: Article

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