P53 isoforms regulate aging- and tumor-associated replicative senescence in T lymphocytes

Journal of Clinical Investigation

Volumn 123, Issue 12, 2013, Pages 5247-5257

  Mondal, Abdul M ^a   Horikawa, Izumi ^a   Pine, Sharon R ^a,b   Fujita, Kaori ^a   Morgan, Katherine M ^b   Vera, Elsa ^c   Mazur, Sharlyn J ^a   Appella, Ettore ^a   Vojtesek, Borivoj ^d   Blasco, Maria A ^c   Lane, David P ^e   Harris, Curtis C ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c Structural Biology and Biocomputing Programme   (Spain)

^d MASARYK MEMORIAL CANCER INSTITUTE   (Czech Republic)

^e INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN; PROTEIN P53; PROTEIN P53 ISOFORM BETA; PROTEIN P53 ISOFORM DELTA 133; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CD 28 T LYMPHOCYTE; CD 57 T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL AGING; CELL DIVISION; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; IN VIVO STUDY; LUNG TUMOR; LYMPHOCYTE PROLIFERATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; T LYMPHOCYTE; TUMOR MICROENVIRONMENT; UPREGULATION;

ADULT; AGED; AUTOPHAGY; CD8-POSITIVE T-LYMPHOCYTES; CELL AGING; CELL DIVISION; CELLS, CULTURED; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEUPEPTINS; LUNG NEOPLASMS; LYMPHOCYTES, TUMOR-INFILTRATING; MACROLIDES; MALE; MIDDLE AGED; NEOPLASM PROTEINS; PROTEIN ISOFORMS; PROTEOLYSIS; RECOMBINANT PROTEINS; TRANSDUCTION, GENETIC; TUMOR MICROENVIRONMENT; TUMOR SUPPRESSOR PROTEIN P53; YOUNG ADULT;

EID: 84890037993     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI70355     Document Type: Article

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