Utilization of extracellular information before ligand-receptor binding reaches equilibrium expands and shifts the input dynamic range

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 37, 2014, Pages E3860-E3869

  Ventura, Alejandra C ^a,b   Bush, Alan ^a,b   Vasen, Gustavo ^a,b   Goldín, Matías A ^a,b   Burkinshaw, Brianne ^a,b   Bhattacharjee, Nirveek ^c   Folch, Albert ^c   Brent, Roger ^d   Chernomoretz, Ariel ^a,e,f   Colman Lerner, Alejandro ^a,b  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Department of Physiology Molecular and Cell Biology School of Exact and Natural Sciences (FCEN)   (United States)

^c University of Washington   (United States)

^d USA   (United States)

^e Ciudad Universitaria   (United States)

^f FUNDACIÓN INSTITUTO LELOIR   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; LIGAND; PROTEIN BINDING;

BIOLOGICAL MODEL; CELL POLARITY; CYTOLOGY; EXTRACELLULAR SPACE; KINETICS; METABOLISM; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; TIME;

CELL POLARITY; EXTRACELLULAR SPACE; KINETICS; LIGANDS; MODELS, BIOLOGICAL; PROTEIN BINDING; RECEPTORS, CELL SURFACE; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84907289342     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1322761111     Document Type: Article

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