-
1
-
-
0037264812
-
Metastasis suppressors alter the signal transduction of cancer cells
-
Steeg PS: Metastasis suppressors alter the signal transduction of cancer cells. Nat Rev Cancer 3: 55-63, 2003.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 55-63
-
-
Steeg, P.S.1
-
2
-
-
0027892999
-
Modulation of in vitro invasion of human glioblastoma cells by urokinase type plasminogen activator receptor antibody
-
Mohanam S, Sawaya R, McCutcheon I, Ali Osman F, Boyd D and Rao JS: Modulation of in vitro invasion of human glioblastoma cells by urokinase type plasminogen activator receptor antibody. Cancer Res 53: 4143-4147, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 4143-4147
-
-
Mohanam, S.1
Sawaya, R.2
McCutcheon, I.3
Ali Osman, F.4
Boyd, D.5
Rao, J.S.6
-
3
-
-
0041737535
-
Molecular mechanisms of glioma invasiveness: The role of proteases
-
Rao JS: Molecular mechanisms of glioma invasiveness: The role of proteases. Nat Rev Cancer 3: 489-501, 2003.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 489-501
-
-
Rao, J.S.1
-
4
-
-
0027384917
-
Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion
-
Davies B, Waxman J, Wasan H, Abel P, Williams G, Krausz T, Neal D, Thomas D, Hanby A and Balkwill F: Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion. Cancer Res 53: 5365-5369, 1993.
-
(1993)
Cancer Res
, vol.53
, pp. 5365-5369
-
-
Davies, B.1
Waxman, J.2
Wasan, H.3
Abel, P.4
Williams, G.5
Krausz, T.6
Neal, D.7
Thomas, D.8
Hanby, A.9
Balkwill, F.10
-
5
-
-
84881321633
-
Histone acetylation: From code to web and router via intrinsically disordered regions
-
Horikoshi M: Histone acetylation: from code to web and router via intrinsically disordered regions. Curr Pharm Des 19: 5019-5042, 2013.
-
(2013)
Curr Pharm des
, vol.19
, pp. 5019-5042
-
-
Horikoshi, M.1
-
6
-
-
84872601036
-
Histone acetylation: Molecular mnemonics on the chromatin
-
Gräff J and Tsai LH: Histone acetylation: molecular mnemonics on the chromatin. Nat Rev Neurosci 14: 97-111, 2013.
-
(2013)
Nat Rev Neurosci
, vol.14
, pp. 97-111
-
-
Gräff, J.1
Tsai, L.H.2
-
7
-
-
0038819943
-
Ineffectiveness of histone deacetylase inhibitors to induce apoptosis involves the transcriptional activation of NF kappa B through the Akt pathway
-
Mayo MW, Denlinger CE, Broad RM, Yeung F, Reilly ET, Shi Y and Jones DR: Ineffectiveness of histone deacetylase inhibitors to induce apoptosis involves the transcriptional activation of NF kappa B through the Akt pathway. J Biol Chem 278: 18980-18989, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 18980-18989
-
-
Mayo, M.W.1
Denlinger, C.E.2
Broad, R.M.3
Yeung, F.4
Reilly, E.T.5
Shi, Y.6
Jones, D.R.7
-
8
-
-
84877773314
-
Specific acetylation of p53 by HDAC inhibition prevents DNA damage induced apoptosis in neurons
-
Brochier C, Dennis G, Rivieccio MA, McLaughlin K, Coppola G, Ratan RR and Langley B: Specific acetylation of p53 by HDAC inhibition prevents DNA damage induced apoptosis in neurons. J Neurosci 33: 8621-8632, 2013.
-
(2013)
J Neurosci
, vol.33
, pp. 8621-8632
-
-
Brochier, C.1
Dennis, G.2
Rivieccio, M.A.3
Mclaughlin, K.4
Coppola, G.5
Ratan, R.R.6
Langley, B.7
-
9
-
-
84875874820
-
Incompatible effects of p53 and HDAC inhibition on p21 expression and cell cycle progression
-
Sachweh MC, Drummond CJ, Higgins M, Campbell J and Laín S: Incompatible effects of p53 and HDAC inhibition on p21 expression and cell cycle progression. Cell Death Dis 4: e533, 2013.
-
(2013)
Cell Death Dis
, vol.4
, pp. e533
-
-
Sachweh, M.C.1
Drummond, C.J.2
Higgins, M.3
Campbell, J.4
Laín, S.5
-
11
-
-
0029693220
-
The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation
-
Van Lint C, Emiliani S and Verdin E: The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation. Gene Expr 5: 245-253, 1996.
-
(1996)
Gene Expr
, vol.5
, pp. 245-253
-
-
Van Lint, C.1
Emiliani, S.2
Verdin, E.3
-
12
-
-
9144220841
-
Transcriptional signature of histone deacetylase inhibition in multiple myeloma: Biological and clinical implications
-
Mitsiades CS, Mitsiades NS, McMullan CJ, et al: Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications. Proc Natl Acad Sci USA 101: 540-545, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 540-545
-
-
Mitsiades, C.S.1
Mitsiades, N.S.2
McMullan, C.J.3
-
13
-
-
21044447215
-
Increased expression of histone deacetylase 2 is found in human gastric cancer
-
Song J, Noh JH, Lee JH, et al: Increased expression of histone deacetylase 2 is found in human gastric cancer. APMIS 113: 264-268, 2005.
-
(2005)
APMIS
, vol.113
, pp. 264-268
-
-
Song, J.1
Noh, J.H.2
Lee, J.H.3
-
14
-
-
11144221007
-
Apoptotic and autophagic cell death induced by histone deacetylase inhibitors
-
Shao Y, Gao Z, Marks PA and Jiang X: Apoptotic and autophagic cell death induced by histone deacetylase inhibitors. Proc Natl Acad Sci USA 101: 18030-18035, 2004.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 18030-18035
-
-
Shao, Y.1
Gao, Z.2
Marks, P.A.3
Jiang, X.4
-
16
-
-
3142702962
-
Invasion of v Fos(FBR) transformed cells is dependent upon histone deacetylase activity and suppression of histone deacetylase regulated genes
-
McGarry LC, Winnie JN and Ozanne BW: Invasion of v Fos(FBR) transformed cells is dependent upon histone deacetylase activity and suppression of histone deacetylase regulated genes. Oncogene 23: 5284-5292, 2004.
-
(2004)
Oncogene
, vol.23
, pp. 5284-5292
-
-
McGarry, L.C.1
Winnie, J.N.2
Ozanne, B.W.3
-
17
-
-
2942724589
-
Histone deacetylase inhibitors: Development as cancer therapy
-
Marks PA, Richon VM, Kelly WK, Chiao JH and Miller T: Histone deacetylase inhibitors: development as cancer therapy. Novartis Found Symp 259: 269-281, 2004.
-
(2004)
Novartis Found Symp
, vol.259
, pp. 269-281
-
-
Marks, P.A.1
Richon, V.M.2
Kelly, W.K.3
Chiao, J.H.4
Miller, T.5
-
18
-
-
0034901985
-
Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo
-
Vigushin DM, Ali S, Pace PE, et al: Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo. Clin Cancer Res 7: 971-976, 2001.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 971-976
-
-
Vigushin, D.M.1
Ali, S.2
Pace, P.E.3
-
19
-
-
53949087611
-
Histone deacetylase inhibitors: The anticancer, antimetastatic and antiangiogenic activities of AN 7 are superior to those of the clinically tested AN 9 (Pivanex)
-
Tarasenko N, Nudelman A, Tarasenko I, et al: Histone deacetylase inhibitors: The anticancer, antimetastatic and antiangiogenic activities of AN 7 are superior to those of the clinically tested AN 9 (Pivanex). Clin Exp Metastasis 25: 703-716, 2008.
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 703-716
-
-
Tarasenko, N.1
Nudelman, A.2
Tarasenko, I.3
-
21
-
-
0038408486
-
Histone deacetylase inhibitor up regulates RECK to inhibit MMP 2 activation and cancer cell invasion
-
Liu LT, Chang HC, Chiang LC and Hung WC: Histone deacetylase inhibitor up regulates RECK to inhibit MMP 2 activation and cancer cell invasion. Cancer Res 63: 3069-3072, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 3069-3072
-
-
Liu, L.T.1
Chang, H.C.2
Chiang, L.C.3
Hung, W.C.4
-
22
-
-
84866908544
-
TET1 suppresses cancer invasion by activating the tissue inhibitors of metalloproteinases
-
Hsu CH, Peng KL, Kang ML, et al: TET1 suppresses cancer invasion by activating the tissue inhibitors of metalloproteinases. Cell Rep 2: 568-579, 2012.
-
(2012)
Cell Rep
, vol.2
, pp. 568-579
-
-
Hsu, C.H.1
Peng, K.L.2
Kang, M.L.3
-
23
-
-
84873411803
-
Tumor development is associated with decrease of TET gene expression and 5 methylcytosine hydroxylation
-
Yang H, Liu Y, Bai F, et al: Tumor development is associated with decrease of TET gene expression and 5 methylcytosine hydroxylation. Oncogene 32: 663-669, 2013.
-
(2013)
Oncogene
, vol.32
, pp. 663-669
-
-
Yang, H.1
Liu, Y.2
Bai, F.3
-
24
-
-
84876531010
-
The HER2 and heregulin beta1 (HRG) inducible TNFR superfamily member Fn14 promotes HRG driven breast cancer cell migration, invasion, and MMP9 expression
-
Asrani K, Keri RA, Galisteo R, et al: The HER2 and heregulin beta1 (HRG) inducible TNFR superfamily member Fn14 promotes HRG driven breast cancer cell migration, invasion, and MMP9 expression. Mol Cancer Res 11: 393-404, 2013.
-
(2013)
Mol Cancer Res
, vol.11
, pp. 393-404
-
-
Asrani, K.1
Keri, R.A.2
Galisteo, R.3
-
25
-
-
77952892382
-
Full length, membrane anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF kappaB pathway
-
Brown SA, Ghosh A and Winkles JA: Full length, membrane anchored TWEAK can function as a juxtacrine signaling molecule and activate the NF kappaB pathway. J Biol Chem 285: 17432-17441, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 17432-17441
-
-
Brown, S.A.1
Ghosh, A.2
Winkles, J.A.3
-
26
-
-
29144447456
-
Anandamide inhibits adhesion and migration of breast cancer cells
-
Grimaldi C, Pisanti S, Laezza C, et al: Anandamide inhibits adhesion and migration of breast cancer cells. Exp Cell Res 312: 363-373, 2006.
-
(2006)
Exp Cell Res
, vol.312
, pp. 363-373
-
-
Grimaldi, C.1
Pisanti, S.2
Laezza, C.3
-
27
-
-
0025778347
-
Tumor cell invasion inhibited by TIMP 2
-
Albini A, Melchiori A, Santi L, Liotta LA, Brown PD and Stetler Stevenson WG: Tumor cell invasion inhibited by TIMP 2. J Natl Cancer Inst 83: 775-779, 1991.
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 775-779
-
-
Albini, A.1
Melchiori, A.2
Santi, L.3
Liotta, L.A.4
Brown, P.D.5
Stetler, S.W.G.6
-
28
-
-
0032974030
-
Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP 3
-
Baker AH, George SJ, Zaltsman AB, Murphy G and Newby AC: Inhibition of invasion and induction of apoptotic cell death of cancer cell lines by overexpression of TIMP 3. Br J Cancer 79: 1347-1355, 1999.
-
(1999)
Br J Cancer
, vol.79
, pp. 1347-1355
-
-
Baker, A.H.1
George, S.J.2
Zaltsman, A.B.3
Murphy, G.4
Newby, A.C.5
-
29
-
-
35148868822
-
Serum levels of matrix metalloproteinases MMP 2 and MMP 9 and their tissue natural inhibitors in breast tumors
-
Jinga D, Stefanescu M, Blidaru A, Condrea I, Pistol G and Matache C: Serum levels of matrix metalloproteinases MMP 2 and MMP 9 and their tissue natural inhibitors in breast tumors. Roum Arch Microbiol Immunol 63: 141-158, 2004.
-
(2004)
Roum Arch Microbiol Immunol
, vol.63
, pp. 141-158
-
-
Jinga, D.1
Stefanescu, M.2
Blidaru, A.3
Condrea, I.4
Pistol, G.5
Matache, C.6
-
30
-
-
0030016640
-
Tissue levels of matrix metalloproteinases MMP 2 and MMP 9 are related to the overall survival of patients with gastric carcinoma
-
Sier CF, Kubben FJ, Ganesh S, et al: Tissue levels of matrix metalloproteinases MMP 2 and MMP 9 are related to the overall survival of patients with gastric carcinoma. Br J Cancer 74: 413-417, 1996.
-
(1996)
Br J Cancer
, vol.74
, pp. 413-417
-
-
Sier, C.F.1
Kubben, F.J.2
Ganesh, S.3
-
31
-
-
41349099104
-
Cancer statistics 2008
-
Jemal A, Siegel R, Ward E, et al: Cancer statistics, 2008. CA Cancer J Clin 58: 71-96, 2008.
-
(2008)
CA Cancer J Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
33
-
-
79960815926
-
Epigenetic therapy for breast cancer
-
Cai FF, Kohler C, Zhang B, Wang MH, Chen WJ and Zhong XY: Epigenetic therapy for breast cancer. Int J Mol Sci 12: 4465-4487, 2011.
-
(2011)
Int J Mol Sci
, vol.12
, pp. 4465-4487
-
-
Cai, F.F.1
Kohler, C.2
Zhang, B.3
Wang, M.H.4
Chen, W.J.5
Zhong, X.Y.6
-
34
-
-
78650575875
-
Selective inhibition of histone deacetylase 6 (HDAC6) induces DNA damage and sensitizes transformed cells to anticancer agents
-
Namdar M, Perez G, Ngo L and Marks PA: Selective inhibition of histone deacetylase 6 (HDAC6) induces DNA damage and sensitizes transformed cells to anticancer agents. Proc Natl Acad Sci USA 107: 20003-20008, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 20003-20008
-
-
Namdar, M.1
Perez, G.2
Ngo, L.3
Marks, P.A.4
-
35
-
-
33645950778
-
Histone deacetylase inhibitors: Multifunctional anticancer agents
-
Liu T, Kuljaca S, Tee A and Marshall GM: Histone deacetylase inhibitors: multifunctional anticancer agents. Cancer Treat Rev 32: 157-165, 2006.
-
(2006)
Cancer Treat Rev
, vol.32
, pp. 157-165
-
-
Liu, T.1
Kuljaca, S.2
Tee, A.3
Marshall, G.M.4
-
36
-
-
0035477320
-
Synergistic activation of functional estrogen receptor (ER) alpha by DNA methyltransferase and histone deacetylase inhibition in human ER alpha negative breast cancer cells
-
Yang X, Phillips DL, Ferguson AT, Nelson WG, Herman JG and Davidson NE: Synergistic activation of functional estrogen receptor (ER) alpha by DNA methyltransferase and histone deacetylase inhibition in human ER alpha negative breast cancer cells. Cancer Res 61: 7025-7029, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 7025-7029
-
-
Yang, X.1
Phillips, D.L.2
Ferguson, A.T.3
Nelson, W.G.4
Herman, J.G.5
Davidson, N.E.6
-
37
-
-
55949105764
-
Epigenetic reprogramming of breast cancer cells by valproic acid occurs regardless of estrogen receptor status
-
Travaglini L, Vian L, Billi M, Grignani F and Nervi C: Epigenetic reprogramming of breast cancer cells by valproic acid occurs regardless of estrogen receptor status. Int J Biochem Cell Biol 41: 225-234, 2009.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 225-234
-
-
Travaglini, L.1
Vian, L.2
Billi, M.3
Grignani, F.4
Nervi, C.5
-
38
-
-
77956627130
-
Trichostatin A enhances acetylation as well as protein stability of ERalpha through induction of p300 protein
-
Kim SH, Kang HJ, Na H and Lee MO: Trichostatin A enhances acetylation as well as protein stability of ERalpha through induction of p300 protein. Breast Cancer Res 12: R22, 2010.
-
(2010)
Breast Cancer Res
, vol.12
, pp. R22
-
-
Kim, S.H.1
Kang, H.J.2
Na, H.3
Lee, M.O.4
-
39
-
-
0038485588
-
Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin A (TSA) and suberoylanilide hydroxamic acid (SAHA)
-
Henderson C, Mizzau M, Paroni G, Maestro R, Schneider C and Brancolini C: Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin A (TSA) and suberoylanilide hydroxamic acid (SAHA). J Biol Chem 278: 12579-12589, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 12579-12589
-
-
Henderson, C.1
Mizzau, M.2
Paroni, G.3
Maestro, R.4
Schneider, C.5
Brancolini, C.6
-
40
-
-
79956302047
-
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
-
Williams K, Christensen J, Pedersen MT, et al: TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 473: 343-348, 2011.
-
(2011)
Nature
, vol.473
, pp. 343-348
-
-
Williams, K.1
Christensen, J.2
Pedersen, M.T.3
-
42
-
-
79958769268
-
Epigenetic aberrations during oncogenesis
-
Hatziapostolou M and Iliopoulos D: Epigenetic aberrations during oncogenesis. Cell Mol Life Sci 68: 1681-1702, 2011.
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 1681-1702
-
-
Hatziapostolou, M.1
Iliopoulos, D.2
-
43
-
-
79251557812
-
Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; Toward selective DNMT inhibitors
-
Chik F and Szyf M: Effects of specific DNMT gene depletion on cancer cell transformation and breast cancer cell invasion; toward selective DNMT inhibitors. Carcinogenesis 32: 224-232, 2011.
-
(2011)
Carcinogenesis
, vol.32
, pp. 224-232
-
-
Chik, F.1
Szyf, M.2
|