The human Rothmund-Thomson syndrome gene product, RECQL4, localizes to distinct nuclear foci that coincide with proteins involved in the maintenance of genome stabiliy

Journal of Cell Science

Volumn 118, Issue 18, 2005, Pages 4261-4269

  Petkovic, Maja ^a   Dietschy, Tobias ^a   Freire, Raimundo ^b   Jiao, Rengie ^a,c   Stagljar, Igor ^a,d  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b HOSPITAL UNIVERSITARIO DE CANARIAS   (Spain)

^c INSTITUTE OF BIOPHYSICS   (China)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Genome stability; Immunofluorescence; Promyelotic leukemia protein (PML); Rad51; RecQ helicases; Rothmund Thompson syndrome (RTS)

Indexed keywords

DOUBLE STRANDED DNA; GENE PRODUCT; PROMYELOCYTIC LEUKEMIA PROTEIN; PROTEIN ANTIBODY; PROTEIN RECQL4; RAD51 PROTEIN; SINGLE STRANDED DNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; FIBROBLAST; GENE EXPRESSION; GENE SILENCING; GENOMIC INSTABILITY; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; ROTHMUND THOMSON SYNDROME;

ADENOSINE TRIPHOSPHATASES; BLOTTING, WESTERN; CELL NUCLEUS; CELLS, CULTURED; DNA DAMAGE; DNA HELICASES; DNA REPAIR; DNA, SINGLE-STRANDED; GENOMIC INSTABILITY; HELA CELLS; HUMANS; NEOPLASM PROTEINS; NUCLEAR PROTEINS; RAD51 RECOMBINASE; RECQ HELICASES; RNA, SMALL INTERFERING; ROTHMUND-THOMSON SYNDROME; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 27144460601     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02556     Document Type: Article

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