Exposure to a northern contaminant mixture (NCM) alters hepatic energy and lipid metabolism exacerbating hepatic steatosis in obese JCR rats

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Mailloux, Ryan J ^a,e   Florian, Maria ^a,e   Chen, Qixuan ^a   Yan, Jin ^a   Petrov, Ivan ^a   Coughlan, Melanie C ^a   Laziyan, Mahemuti ^a,e   Caldwell, Don ^b   Lalande, Michelle ^b   Patry, Dominique ^b   Gagnon, Claude ^c   Sarafin, Kurtis ^c   Truong, Jocelyn ^f   Chan, Hing Man ^f   Ratnayake, Nimal ^c   Li, Nanqin ^d   Willmore, William G ^e   Jin, Xiaolei ^a  

^a TOXICOLOGY RESEARCH DIVISION   (Canada)

^b HEALTH CANADA   (Canada)

^c Bureau of Nutritional Sciences   (Canada)

^d Environmental Health Center   (Canada)

^e CARLETON UNIVERSITY   (Canada)

^f UNIVERSITY OF OTTAWA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CHOLESTEROL; CHOLESTEROL ESTER; CREATINE KINASE; CYTOCHROME P450 2E1; FAT DROPLET; FLAME RETARDANT; LIPID; MONOUNSATURATED FATTY ACID; ORGANOCHLORINE PESTICIDE; POLYCHLORINATED BIPHENYL; POLYUNSATURATED FATTY ACID; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; UBIQUINONE; ADENOSINE TRIPHOSPHATE; POLLUTANT;

ALCOHOL ABUSE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CANADA; CHOLESTEROL LIVER LEVEL; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DISEASE COURSE; DISEASE EXACERBATION; ENZYME ACTIVITY; FATTY LIVER; GENE EXPRESSION; HOMEOSTASIS; LIPID METABOLISM; LIPID TRANSPORT; LIVER DISEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; NONHUMAN; NORTH AMERICA; NORTHERN CONTAMINANT MIXTURE; OBESITY; PERSISTENT ORGANIC POLLUTANT; PROTEIN EXPRESSION; RAT; ADVERSE EFFECTS; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; ENVIRONMENTAL EXPOSURE; HUMAN; INBRED RAT STRAIN; INUIT; LIVER; METABOLISM; POLLUTANT;

RATTUS;

ADENOSINE TRIPHOSPHATE; ANIMALS; CHOLESTEROL; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; ETHANOL; FATTY LIVER; HOMEOSTASIS; HUMANS; INUITS; LIPID METABOLISM; LIVER; RATS, INBRED STRAINS;

EID: 84907168982     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106832     Document Type: Article

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