Effect of pesticides on cell survival in liver and brain rat tissues

Ecotoxicology and Environmental Safety

Volumn 72, Issue 7, 2009, Pages 2025-2032

  Astiz, Mariana ^a   Alaniz, María J T de ^a   Marra, Carlos Alberto ^a  

^a INSTITUTO DE INVESTIGACIONES BIOQUÍMICAS DE LA PLATA INIBIOLP   (Argentina)

Author keywords

Brain; Cardiolipin; Cell death; Dimethoate; Glyphosate; Liver; Mitochondria; Oxidative stress; Pesticides; Zineb

Indexed keywords

CARDIOLIPIN; DIMETHOATE; GLYPHOSATE; PESTICIDE; ZINEB;

DISEASE TREATMENT; DOSE-RESPONSE RELATIONSHIP; ENVIRONMENTAL FACTOR; FRAGMENTATION; MITOCHONDRIAL DNA; PESTICIDE; RODENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; CELL SURVIVAL; CONTROLLED STUDY; DNA FRAGMENTATION; LIPID PEROXIDATION; LIVER CELL; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; RAT; WISTAR RAT;

ANIMALS; APOPTOSIS; BRAIN; CARDIOLIPINS; CELL SURVIVAL; DNA FRAGMENTATION; ENVIRONMENTAL POLLUTANTS; FATTY ACIDS; LIPID PEROXIDATION; LIVER; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; PESTICIDES; RATS; RATS, WISTAR;

RATTUS; RATTUS NORVEGICUS;

EID: 70249120657     PISSN: 01476513     EISSN: 10902414     Source Type: Journal    
DOI: 10.1016/j.ecoenv.2009.05.001     Document Type: Article

References (84)

1. Abuja P.M., and Albertini R. Methods for monitoring oxidative stress, lipid peroxidation and oxidation resistance of lipoproteins. Clin. Chim. Acta 306 (2001) 1-17
2. Aldridge J., Gibbons J., Flaherty M., Kreider M., Romano J., and Levin E. Heterogeneity of toxicant response: sources of human variability. Toxicol. Sci. 76 (2003) 3-20
3. Anderson M.E., and Meister A. Enzymic assay of GSSG plus GSH. Method Enzymol. 105 (1984) 448-450
4. Bagchi D., Bagchi M., Hassoun E.A., and Stohs S.J. In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides. Toxicology 104 (1995) 129-140
5. Banerjee B.D., Seth A., Bhattacharya A., Pasha S.T., and Chakraborty A.K. Biochemical effects of some pesticides on lipid peroxidation and free radical scavengers. Toxicol. Lett. 107 (1999) 33-47
6. Barlow B.K., Lee D.W., Cory-Slechta D.A., and Opanashuk L.A. Modulation of antioxidant defense systems by the environmental pesticide Maneb in dopaminergic cells. Neurotoxicology 26 (2005) 63-75
7. Bayir H., Tyurin V.A., Tyurina Y.Y., Viner R., Ritov V., Amoscato A.A., Zhao Q., Zhang X.J., Janesko-Feldman K.L., Alexander H., Basova L.V., Clark R.S.B., Kochanek P.M., and Kagan V.A. Selective early cardiolipin peroxidation after traumatic brain injury: an oxidative lipidomic analysis. Ann. Neurol. 62 (2007) 154-169
8. Beuret C.J., Zirulnik F., and Gimenez M.S. Effect of the herbicide glyphosate on liver lipoperoxidation in pregnant rats and their fetuses. Reprod. Toxicol. 19 (2005) 501-504
9. Bizat N., Hermel J.M., Boyer F., Jacquard C., Créminon C., Ouary S., Escartin C., Krajewski S., Hantraye P., and Brouillet E. Calpain is a major cell death effector in selective striatal degeneration induced in vivo by 3-Nitropropiate: Implications in Huntington's disease. J. Neurosci. 23 (2003) 5020-5030
10. Bizat N., Hermel J.M., Humbert S., Jacquard C., Créminon C., Escartin C., Saudou F., Krajewski S., Hantraye P., and Brouillet E. In vivo Calpain/caspase cross-talk during 3-Nitropropionic acid-induced striatal degeneration. J. Biol. Chem. 278 (2003) 43245-43253
11. Bolognesi C., and Morasso G. Genotoxicity of pesticides: potential risk for consumers. Trends Food Sci. Technol. 11 (2000) 182-187
12. Botha N., Gehringer M.M., Downing T.G., van de Venter M., and Shephard E.G. The role of microcystin-LR in the induction of apoptosis and oxidative stress in CaCo2 cells. Toxicon 43 (2004) 85-92
13. Chen M.J., Yap Y.M., Choy M.S., Koh C.H., Seet S.J., Duan W., Whiteman M., and Cheung N.S. Early induction of calpains in rotenone-mediated neuronal apoptosis. Neurosci. Lett. 397 (2006) 69-73
14. Chen P.S., Toribara T.Y., and Warner H. Microdetermination of phosphorus. Anal. Chem. 28 (1956) 1756-1758
15. Chong Z.Z., Li F., and Maiese K. Oxidative stress in the brain: novel cellular targets that govern survival during neurodegenerative disease. Prog. Neurobiol. 75 (2005) 207-246
16. Chua B.T., Guo K., and Li P. Direct cleavage by the calcium-activated protease calpain can lead to inactivation of caspases. J. Biol. Chem. 275 (2000) 5131-5135
17. Cory-Slechta D.A. Studying toxicants as single chemicals: does this strategy adequately identify neurotoxic risk?. Neurotoxicology 26 (2005) 491-510
18. Daruich J., Zirulnik F., and Gimenez M.S. Effect of the herbicide glyphosate on enzymatic activity in pregnant rats and their fetuses. Environ. Res. 85 (2001) 226-231
19. Dauer W., and Przedborski S. Parkinson's disease: mechanisms and models. Neuron 39 (2003) 889-909
20. De Zwart L.L., Meerman J.H., Commandeur J.M.N., and Vermeulen N.P.E. Biomarkers of free radical damage applications in experimental animals and in humans. Free Radical Biol. Med. 26 (1999) 202-226
21. Di Monte D. The environment and Parkinson's disease: is the nigrostriatal system preferentially targeted by neurotoxins?. Lancet Neurol. 2 (2003) 531-537
22. Eguchi Y., Shimizu S., and Tsujimoto Y. Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res. 57 (1997) 1835-1840
23. Ellman G.L. Tissue sulphydryl groups. Arch. Biochem. Biophys. 8 (1959) 70-77
24. Erikson K.M., Pinero D.J., Connor J.R., and Beard J.L. Regional brain iron, ferritin and transferrin concentrations during iron deficiency and iron repletion in developing rats. J. Nutr. 127 (1997) 2030-2038
25. Esposti M.D. Lipids, Cardiolipin and apoptosis: a greasy licence to kill. Cell Death Differ. 9 (2002) 234-236
26. Fernandez-Checa J.C. Redox regulation and signaling lipids in mitochondrial apoptosis. Biochem. Biophys. Res. Commun. 304 (2003) 471-479
27. Fitsanakis V.A., Amarnath V., Moore J.T., Montine K.S., Zhang J., and Montine T.J. Catalysis of catechol oxidation by metal-dithiocarbamate complexes in pesticides. Free Radical Biol. Med. 33 (2002) 1714-1723
28. Folch J., Lees M., and Sloane Stanley G.H. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226 (1957) 497-509
29. Gao H.M., Liu B., Zhang W., and Hong J.S. Novel anti-inflammatory therapy of Parkinson's disease. Trends Pharmacol. Sci. 24 (2003) 395-401
30. Gorman A.M., Mc Gowan A., O′Neill C., and Cotter T. Oxidative stress and apoptosis in neurodegeneration. J. Neurol. Sci. 139 (1996) 45-52
31. Griffiths H.R., Møller L., Bartosz G., Bast A., Bertoni-Freddari C., Collins A., Cooke M., Coolen S., Haenen G., Hoberg A.M., Loft S., Lunec J., Olinski R., Parry J., Pompella A., Poulsen H., Verhagen H., and Astley S.B. Biomarkers. Mol. Aspects Med. 23 (2002) 101-208
32. Halliwell B., and Gutteridge J.M.C. Free Radicals in Biology and Medicine. third ed (1999), Oxford Science Publications
33. Hatch G.M., Vance D.E., and Wilton D.C. Rat liver mitochondrial phospholipase A2 is an endotoxin-stimulated membrane-associated enzyme of Kupffer cells which is released during liver perfusion. Biochem. J. 293 (1993) 143-150
34. Heikkila R.E., Cabbat F.S., and Cohen G. In vivo inhibition of superoxide dismutase in mice by diethyldithiocarbamate. J. Biol. Chem. 251 (1976) 2182-2185
35. Honig L.S., and Rosenberg R.N. Apoptosis and neurologic disease. Am. J. Med. 108 (2000) 317-330
36. Hultberg M. Cysteine turnover in human cell lines is influenced by glyphosate. Environ. Toxicol. Pharmacol. 24 (2007) 19-22
37. Iverson S.L., and Orrenius S. The cardiolipin-cytocrome c interaction and the mitochondrial regulation of apoptosis. Arch. Biochem. Biophys. 423 (2004) 37-46
38. Jackson M.J., Papa S., Bolaños J., Bruckdorfer R., Carlsen H., Elliott M.R., Flier J., Griffiths H.R., Heales S., Holst B., Lorusso M., Lund E., Moskaug J., Moser U., Di Paola M., Polidori C., Signorile A., Stahl W., Viña-Ribes J., and Astley S.B. Antioxidants, reactive oxygen and nitrogen species, gene induction and mitochondrial function. Mol. Aspects Med. 23 (2002) 209-285
39. John S., Kale M., Rathore N., and Bhatnagar D. Protective effect of vitamin E in dimethoate and malathion induced oxidative stress in rat erythrocytes. J. Nutr. Biochem. 12 (2001) 500-504
40. Kagan V.E., Tyurina Y.Y., Bayir H., Chu C.T., Kapralov A.A., Vlasova I.I., Belikova N.A., Tyurin V.A., Amoscato A., Epperly M., Greenberger J., DeKosky S., Shvedova A.A., and Jiang J. The "pro-apoptotic genies" get out of mitochondria: oxidative lipidomics and redox activity of cytocrome c/cardiolipin complexes. Chem. Biol. Interact. 163 (2006) 15-28
41. Kanthasamy A.G., Kitazawa M., Kanthasamy A., and Anantharam V. Dieldrin-induced neurotoxicity: relevance to Parkinson's disease pathogenesis. Neurotoxicology 26 (2005) 701-719
42. Kirkland R.A., Adibhatla R.M., Hatcher J.F., and Franklin J.L. Loss of cardiolipin and mitochondria during programmed neuronal death: evidence of the role for lipid peroxidation and autophagy. Neuroscience 115 (2002) 587-602
43. Kritchevsky D., Davidson L.M., Kim H.K., and Malhotra S. Quantitation of serum lipids by a simple TLC-charring method. Clin. Chim. Acta 46 (1972) 63-68
44. Le Couteur D.G., Mc Lean A.J., Taylor M.C., Woodham B.L., and Board P.G. Pesticides and Parkinson's disease. Biomed. Pharmacother. 53 (1999) 122-130
45. Liu B., Gao H.-M., and Hong J.-S. Parkinson's disease and exposures to infectious agents and pesticides and the occurrence of brain injuries: role of neuroinflammation. Environ. Health Persp. 111 (2003) 1065-1073
46. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin-phenol reagent. J. Biol. Chem. 193 (1951) 265-275
47. McMillin J.B., and Dowhan W. Cardiolipin and apoptosis. Biochim. Biophys. Acta 1585 (2002) 97-107
48. Mensink H., and Janssen P. Glyphosate. Environmental Health Criteria vol. 159 (1994), World Health Organization, Geneva
49. Moser V.C., Simmons J.E., and Gennings C. Neurotoxicological interactions of a five-pesticide mixture in preweanling rats. Toxicol. Sci. 92 (2006) 235-245
50. Nakamura K., and Handa S. Coomasie brilliant blue staining of lipids on thin-layer plates. Anal. Biochem. 142 (1984) 406-410
51. National Research Council. Guide for the Care and Use of Laboratory Animals, Publication No. 85-23 (rev.) (1985), National Institute of Health, Bethesda, MD
52. Nielsen B.S., Larsen E.H., Ladefoged O., and Rye Lam H. Neurotoxic effect of maneb in rats as studied by neurochemical and immunohistochemical parameters. Environ. Toxicol. Pharmacol. 21 (2006) 268-275
53. Orrenius S. Mitochondrial regulation of apoptotic cell death. Toxicol. Lett. 149 (2004) 19-23
54. Ostrander D.B., Sparagna G.C., Amoscato A.A., McMillin J.B., and Dowhan W. Decreased cardiolipin synthesis corresponds to cytochrome c release in palmitate-induced cardiomyocite apoptosis. J. Biol. Chem. 276 (2001) 38061-38067
55. Ott M., Robertson J.D., Gogvadze V., Zhivitivsky B., and Orrenius S. Cytocrome c release from mitochondria proceeds by a two-step process. Proc. Natl. Acad. Sci. USA 5 (2002) 1259-1263
56. Paolini M., Sapone A., and Gonzalez F.J. Parkinson's disease, pesticides and individual vulnerability. Trends Pharmacol. Sci. 25 (2004) 124-129
57. Paradies G., Petrosillo G., Pistolese M., and Ruggiero F.M. The effect of reactive oxygen species generated from the mitochondrial electron transport chain on the cytochrome c oxidase activity and on the cardiolipin content in bovine heart submitochondrial particles. FEBS Lett. 466 (2000) 323-326
58. Paradies G., Petrosillo G., Pistolese M., and Ruggiero F.M. Reactive oxygen species affect mitochondrial electron transport complex I activity through oxidative cardiolipin damage. Gene 286 (2002) 135-141
59. Patel S., Singh V., Kumar A., Gupta Y.K., and Singh M.P. Status of antioxidant defense system and expression of toxicant responsive genes in striatum of maneb- and paraquat-induced Parkinson′s disease phenotype in mouse: mechanism of neurodegeneration. Brain Res. 1081 (2006) 9-18
60. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. fourth ed (1998), Academic Press, New York
61. Petrosillo G., Ruggiero F.M., and Paradies G. Role of reactive oxygen species in the release of cytochrome c from mitochondria. FASEB J. 17 (2003) 2202-2207
62. Petrosillo G., Ruggiero F.M., Pistolese M., and Paradies G. Reactive oxygen species generated from the mitochondrial electron transport chain induce cytochrome c dissociation from beef-heart submitochondrial particles via cardiolipin peroxidation. Possible role in apoptosis. FEBS Lett. 509 (2001) 435-438
63. Pfeiffer K., Gohil V., Stuart R.A., Hunte C., Brandt U., Greenberg M.L., and Schägger H. Cardiolipin stabilizes respiratory chain supercomplexes. J. Biol. Chem. 278 (2003) 52873-52880
64. Pope S., Land J.M., and Heales S.J.R. Oxidative stress and mitochondrial dysfunction in neurodegeneration; cardiolipin a critical target?. Biochim. Biophys. Acta 1777 (2008) 794-799
65. Rami A., Agarwal R., Botez G., and Winckler J. μ-Calpain activation, DNA fragmentation, and synergistic effects of caspase and calpain inhibitors in protecting hippocampal neurons from ischemic damage. Brain Res. 866 (2000) 299-312
66. Raynaud F., and Marcilhac A. Implication of calpain in neuronal apoptosis a possible regulation of Alzheimer's disease. FEBS J. 273 (2006) 3437-3443
67. Reers M., Smith T.W., and Chen L.B. J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential. Biochemistry 30 (1991) 4480-4486
68. Ricci J.E., Gottlieb R.A., and Green D.R. Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis. J. Cell Biol. 160 (2003) 65-75
69. Samantaray S., Knaryan V.H., Guyton M.K., Matzelle D.D., Ray S.K., and Banik N.L. The parkinsonian neurotoxin rotenone activates calpain and caspase-3 leading to motoneuron degeneration in spinal cord of lewis rats. Neuroscience 146 (2007) 741-755
70. Sambrook J., Fritsch E., and Maniatis T. Molecular Cloning: A Laboratory Manual (1989), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY (USA)
71. Schlame M., and Rüstow B. Lysocardiolipin formation and reacylation in isolated rat liver mitochondria. Biochem. J. 272 (1990) 589-595
72. Sen T., Sen N., Tripathi G., Chatterjee U., and Chakrabarti S. Lipid peroxidation associated cardiolipin loss and membrane depolarization in rat brain mitochondria. Neurochem. Int. 49 (2006) 20-27
73. Sharma Y., Bashir S., Irshad M., Nag T.C., and Dogra T.D. Dimethoate-induced effects on antioxidant status of liver and brain of rats following sub chronic exposure. Toxicology 215 (2005) 173-181
74. Sharma Y., Bashir S., Irshad M., Datta Gupta S., and Dogra T.D. Effects of acute dimethoate administration on antioxidant status of liver and brain of experimental rats. Toxicology 206 (2005) 49-57
75. Shidoji Y., Hayashi K., Komura S., Ohishi N., and Yagi K. Loss of molecular interaction between cytocrome c and cardiolipin due to lipid peroxidation. Biochem. Biophys. Res. Commun. 264 (1999) 343-347
76. Singh S., and Dikshit M. Apoptotic neuronal death in Parkinson's disease: Involvement of nitric oxide. Brain Res. Rev. 54 (2007) 233-250
77. Sivapiriya V., Jayanthisakthisekaran, and Venkatraman S. Effects of dimethoate (O,O-dimethyl S-methyl carbamoyl methyl phosphorodithioate) and ethanol in antioxidant status of liver and kidney of experimental mice. Pestic. Biochem. Phys. 85 (2006) 115-121
78. Stewart V.C., and Heales S.J.R. Nitric oxide-induced mitochondrial dysfunction: implications for neurodegeneration. Free Radical Biol. Med. 34 (2003) 287-303
79. Thiruchelvam M., Richfield E.K., Goodman B.M., Baggs R.B., and Cory-Slechta D.A. Developmental exposure to the pesticides Paraquat and Maneb and the Parkinson's disease phenotype. Neurotoxicology 23 (2002) 621-633
80. van der Berg J.J., Op den Kamp J.S., Lubin B.H., and Kuypers F.A. Conformational changes in oxidized phospholipids and their preferential hydrolysis by phospholipase A2: a monolayer study. Biochemistry 32 (1993) 4962-4967
81. Von Ahsen O., Waterhouse N.J., Kuwana T., Newmeyer D.D., and Green D.R. The "harmless" release of cytochrome c. Cell Death Differ. 7 (2000) 1192-1199
82. Wang K.K., Posmantur R., Nadimpalli R., Nath R., Mohan P., Nixon R.A., Talanian R.V., Keegan M., Herzog L., and Allen H. Caspase-mediated fragmentation of calpain inhibitor protein calpastatin during apoptosis. Arch. Biochem. Biophys. 356 (1998) 187-196
83. Yagi K. A simple flourometric assay for lipoperoxides in blood plasma. Biochem. Med. 15 (1976) 212-216
84. Zhang J., Perry G., Smith M.A., Robertson D., Olson S.J., Graham D.G., and Montine T.J. Parkinson's disease is associated with oxidative damage to cytoplasmatic DNA and RNA in substantia nigra neurons. Am. J. Pathol. 154 (1999) 1423-1429