The role of p38 signaling and poly(ADP-ribosyl)ation-induced metabolic collapse in the osteogenic differentiation-coupled cell death pathway

Free Radical Biology and Medicine

Volumn 76, Issue , 2014, Pages 69-79

  Robaszkiewicz, Agnieszka ^a,b   Valkó, Zsuzsanna ^a   Kovács, Katalin ^a,c   Hegedus, Csaba ^a   Bakondi, Edina ^a   Bai, Péter ^a,c,d,e   Virág, László ^a,c  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b UNIVERSITY OF LODZ   (Poland)

^c MTA DE Cell Biology Signaling Research Group   (Hungary)

^d UNIVERSITY OF DEBRECEN   (Hungary)

^e MTA DE 'Lendulet' Immunogenomics Research Group   (Hungary)

Author keywords

Cell death; Hydrogen peroxide; Osteogenic differentiation; p38 MAP kinase; PARP1; Poly(ADP ribosyl)ation

Indexed keywords

ALKALINE PHOSPHATASE; CATALASE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 3; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ARTICLE; CELL CULTURE; CELL DEATH; CELL DIFFERENTIATION; CELL VIABILITY; COMET ASSAY; CONTROLLED STUDY; CYTOPLASM; DNA STRAND BREAKAGE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; MESENCHYMAL STEM CELL; MITOCHONDRIAL RESPIRATION; OSTEOSARCOMA CELL; SIGNAL TRANSDUCTION; WESTERN BLOTTING; APOPTOSIS; BONE DEVELOPMENT; BONE TUMOR; CELL PROLIFERATION; CHORION; DNA DAMAGE; ENERGY METABOLISM; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; OSTEOSARCOMA; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

APOPTOSIS; BLOTTING, WESTERN; BONE NEOPLASMS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CHORION; COMET ASSAY; DNA DAMAGE; ENERGY METABOLISM; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOPRECIPITATION; MESENCHYMAL STROMAL CELLS; MITOGEN-ACTIVATED PROTEIN KINASE 3; OSTEOGENESIS; OSTEOSARCOMA; OXIDATIVE STRESS; POLY(ADP-RIBOSE) POLYMERASES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84907167682     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2014.07.027     Document Type: Article

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