Bone morphogenetic protein-2 activates NADPH oxidase to increase endoplasmic reticulum stress and human coronary artery smooth muscle cell calcification

Biochemical and Biophysical Research Communications

Volumn 413, Issue 3, 2011, Pages 436-441

  Liberman, Marcel ^a   Johnson, Rebecca C ^a   Handy, Diane E ^a   Loscalzo, Joseph ^a   Leopold, Jane A ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Bone morphogenetic protein 2; Endoplasmic reticulum stress; Oxidant stress; Vascular calcification; Vascular smooth muscle cells

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; GLUCOSE REGULATED PROTEIN 78; PROTEIN IRE1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMAD1 PROTEIN; TRANSCRIPTION FACTOR RUNX2; X BOX BINDING PROTEIN 1;

ARTICLE; BINDING SITE; CALCIUM CELL LEVEL; CONTROLLED STUDY; CORONARY ARTERY CALCIFICATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MINERALIZATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER;

BONE MORPHOGENETIC PROTEIN 2; CALCINOSIS; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; CORONARY VESSELS; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; GENE EXPRESSION REGULATION; HUMANS; MYOCYTES, SMOOTH MUSCLE; NADPH OXIDASE; OXIDATIVE STRESS; PROMOTER REGIONS, GENETIC; TRANSCRIPTION FACTORS;

EID: 80053295977     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.08.114     Document Type: Article

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