Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and period proteins in the mammalian circadian clock

Genes and Development

Volumn 28, Issue 18, 2014, Pages 1989-1998

  Ye, Rui ^a   Selby, Cristopher P ^a   Chiou, Yi Ying ^a   Ozkan Dagliyan, Irem ^a   Gaddameedhi, Shobhan ^a   Sancar, Aziz ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Circadian; Cryptochrome; DNA binding; Period; Transcription

Indexed keywords

CRYPTOCHROME 1; CRYPTOCHROME 2; PER1 PROTEIN; PER2 PROTEIN; PROTEIN BMAL1; TRANSCRIPTION FACTOR CLOCK; CIRCADIAN RHYTHM SIGNALING PROTEIN; CRY1 PROTEIN, MOUSE; CRYPTOCHROME; MULTIPROTEIN COMPLEX; PER2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR ARNTL;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MUTANT; CIRCADIAN RHYTHM; DELETION MUTANT; FEEDBACK SYSTEM; GENE CONTROL; GENETIC TRANSCRIPTION; GENOTYPE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOFLUORESCENCE MICROSCOPY; MOUSE; NONHUMAN; PROMOTER REGION; REPRESSOR GENE; SKIN FIBROBLAST; TRANSCRIPTION TRANSLATION FEEDBACK LOOP; ACTIVE TRANSPORT; ANIMAL; CELL LINE; CIRCADIAN; DNA BINDING; GENETICS; METABOLISM; MUTATION; PERIOD; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; TRANSCRIPTION;

CIRCADIAN; CRYPTOCHROME; DNA BINDING; PERIOD; TRANSCRIPTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ARNTL TRANSCRIPTION FACTORS; CELL LINE; CIRCADIAN CLOCKS; CLOCK PROTEINS; CRYPTOCHROMES; MICE; MULTIPROTEIN COMPLEXES; MUTATION; PERIOD CIRCADIAN PROTEINS; PROTEIN STRUCTURE, TERTIARY;

EID: 84907146186     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.249417.114     Document Type: Article

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