Rhythmic PER Abundance Defines a Critical Nodal Point for Negative Feedback within the Circadian Clock Mechanism

Molecular Cell

Volumn 36, Issue 3, 2009, Pages 417-430

  Chen, Rongmin ^a   Schirmer, Aaron ^b   Lee, Yongjin ^a   Lee, Hyeongmin ^a   Kumar, Vivek ^b,d   Yoo, Seung Hee ^b,d   Takahashi, Joseph S ^b,c,d   Lee, Choogon ^a  

^a FLORIDA STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

MOLNEURO; PROTEINS; SIGNALING

Indexed keywords

PROTEIN BMAL1; TRANSCRIPTION FACTOR CLOCK;

ANIMAL CELL; ARTICLE; BIOCHEMISTRY; BRAIN; CIRCADIAN RHYTHM; CONTROLLED STUDY; CRY1 GENE; FIBROBLAST; GENE; GENE EXPRESSION; LIVER; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; OSCILLATION; PER2 GENE; PROTEIN BINDING; TRANSGENIC MOUSE;

ANIMALS; ARNTL TRANSCRIPTION FACTORS; BIOLOGICAL CLOCKS; CELLS, CULTURED; CIRCADIAN RHYTHM; CLOCK PROTEINS; CRYPTOCHROMES; FIBROBLASTS; GENE EXPRESSION PROFILING; GREEN FLUORESCENT PROTEINS; IMMUNOBLOTTING; LIVER; LUCIFERASES; LUMINESCENT MEASUREMENTS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; PERIOD CIRCADIAN PROTEINS; PROTEIN BINDING;

MAMMALIA; MUS MUSCULUS;

EID: 70449093653     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molcel.2009.10.012     Document Type: Article

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