Does nasal nitric oxide come from the sinuses?

Journal of Otolaryngology

Volumn 28, Issue 4, 1999, Pages 197-204

  Haight, Jim S J ^a,e   Djupesland, P G ^c   Qjan, W ^b   Chatkin, J M ^d   Furlott, H ^a   Irish, Jonathan ^a   Witterick, Ian ^a   McClean, P ^a   Fenton, R S ^a   Hoffstein, V ^a   Zamel, N ^a  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b AFFILIATED PEOPLE S HOSPITAL OF JIANGSU UNIVERSITY   (China)

^c UNIVERSITY OF OSLO   (Norway)

^d PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^e NONE   (Canada)

Author keywords

Lidocaine; Nitric oxide; Nose; Paranasal sinuses; Sinus ostia

Indexed keywords

LIDOCAINE; NITRIC OXIDE;

ADULT; AIRFLOW; ARTICLE; FRONTAL SINUS; GAS EXCHANGE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; NOSE CAVITY; NOSE SECRETION; PARANASAL SINUS; PRIORITY JOURNAL;

CHEMILUMINESCENT MEASUREMENTS; HUMANS; MALE; MIDDLE AGED; NASAL MUCOSA; NITRIC OXIDE; PARANASAL SINUSES;

EID: 0032826826     PISSN: 03816605     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Lundberg JON, Lundberg JM, Settergren G, et al. Nitric oxide, produced in the upper airways, may act as an "aerocrine" fashion to enhance pulmonary uptake in humans. Acta Physiol Scand 1995;155:467-468.
2. Lindberg S, Cervin A, Runer T. Nitric oxide production in the upper airways is decreased in chronic sinusitis. Acta Otolaryngol (Stockh) 1997;117:113-117.
3. Jannert M, Andréasson L, Ivarsson A. Patency tests of the maxillary ostium in health and disease. Rhinology 1982; 20:237-242.
4. Lundberg JON, Farkas-Szaliasi T, Weitzberg E, et al. High nitric oxide production in human paranasal sinuses. Nature Med 1995; 1:370-373.
5. Schedin U, Norman M, Gustaffson LE, et al. Endogenous nitric oxide in the upper airway of premature and term infants. Acta Paediatr 1997; 86:1229-1235.
6. Aust R, Drettner B. The patency of the maxillary ostium in relation to body posture. Acta Otolaryngol 1975; 80:443-446.
7. Chatkin JM, Djupesland PG, Qian W, et al. Nasal nitric oxide is independent of nasal cavity volume. Am J Rhinol 1999 (in press).
8. Ramis I, Lorente J, Rosello-Catafau J, et al. Differential activity of nitric oxide synthase in human nasal mucosa and polyps. Eur Respir J 1996; 9:202-206.
9. Qian W, Djupesland PG, Chatkin JM, et al. Aspiration flow optimized for nasal nitric oxide measurement. Rhinology 1999 (in press).
10. Silkoff P, Chatkin JM, Qian W, et al. A comparison of techniques for measuring nasal nitric oxide. Am J Rhinol 1999 (in press).
11. Lang J. Clinical anatomy of nose, nasal cavity and paranasal sinuses. New York: Thieme, 1989.
12. Hollinshead WH. Head and neck. In: Hollinshead WH, ed. Anatomy for surgeons. Hagerstown, MD: Harper and Row, 1968:619.
13. Drettner B, Aust R. Plethysmographic studies of the blood flow in the mucosa of the human maxillary sinus. The rate of perfusion of the maxillary sinus is high. Acta Otolaryngol 1974; 78:259-262.
14. Djupesland PG, Chatkin JM, Qian W, et al. Aerodynamic influences on nasal nitric oxide output. Acta Otolaryngol (Stockh) 1999 (in press).
15. Kalender W, Rettinger G, Suess C. Measurement of paranasal sinus ventilation by xenon dynamic computer tomography. J Comp Assist Tomogr 1985; 9:524-529.
16. Paulsson B, Bende M, Larsson I, et al. Ventilation of the paranasal sinuses studied with dynamic emission computer tomography. Laryngoscope 1992; 102:451-457.
17. Lundberg JON, Weitzberg E, Rinder J, et al. Calcium-independent and steroid-resistant nitric oxide synthase activity in human paranasal sinus mucosa. Eur Respir J 1996; 9: 1344-1347.
18. Ritter FN. The paranasal sinuses, anatomy and surgical technique. St Louis: CV Mosby, 1978.
19. DuBois AB, Douglas JS, Stitt JT, et al. Production and absorption of nitric oxide gas in the nose. J Appl Physiol 1998; 84:1217-1224.
20. Lundberg JON, Rinder J, Weitzberg E, et al. Nasally exhaled nitric oxide in humans originates mainly in the paranasal sinuses. Acta Physiol Scand 1994; 152:431-432.
21. Imada M, Iwamoto J, Nonaka S, et al. Measurement of nitric oxide in human nasal airway. Eur Respir J 1996; 9: 556-559.
22. Rosbe KW, Mims JW, Prazma J, et al. Immunohistochemical localization of nitric oxide synthase activity in upper respiratory epithelium. Laryngoscope 1996; 106:1075-1079.
23. Furukawa K, Harrison DG, Saleh H, et al. Expression of nitric oxide synthase in the human nasal mucosa. Am J Respir Crit Care Med 1996; 153:847-850.
24. De Sanctis GT, Mehta S, Kobzik L, et al. Contribution of type I NOS to expired gas and bronchial responsiveness in mice. Am J Physiol 1997; 273:883-888.
25. Aust R. Oxygen exchange through the maxillary ostium in man. Rhinology 1974; 12:25-35.
26. Müsebeck K, Rosenberg H. Measurement of air flow in the maxillary sinus by hot-film technique. Rhinology 1978; 16:11-18.
27. Drettner B, Aust R. Pathophysiology of the paranasal sinuses. Acta Otolaryngol 1977; 83:16-19.
28. Svanholm H, Falk B, Aust R. Ventilatory effects of the pulse wave in the maxillary sinus. Rhinology 1981; 19:41-46.
29. Bachert C, Ganzer U. Experimental studies on the relationship between maxillary sinus ventilation and various obstructions of the nose and nasopharynx. Rhinology 1989; 27:37-43.
30. Jain B, Rubenstein I, Robbins RA, et al. Modulation of airway epithelial cell ciliary beat frequency by nitric oxide. Biochem Biophys Res Commun 1993; 191:83-88.
31. Lindberg S, Cervin A, Runer T. Low levels of nasal nitric oxide (NO) correlate with impaired mucociliary function in the upper airways. Acta Otolaryngol (Stockh) 1997; 117: 728-734.
32. Croen K. Evidence of an antiviral effect of nitric oxide. Inhibition of herpes simplex virus type 1 replication. J Clin Invest 1993; 91:2446-2452.
33. Mancinelli R, McKay C. Effect of nitric oxide and nitrogen dioxide in bacterial growth. Appl Environ Microbiol 1983; 46:198-202.
34. Barnes P, Kharitonov S. Exhaled nitric oxide: a new lung function test. Thorax 1996; 51:233-237.
35. Moilanen E, Vapaatalo H. Nitric oxide in inflammation and immune response. Ann Med 1995; 27:359-367.
36. Leiberman A, Ohki M, Cole P. The open mouth and oronasal breathing. Am J Rhinol 1991; 5:1-5.
37. Chatkin JM, Silkoff P, Qian W, et al. The measurement of nitric oxide accumulation in the non-ventilated nasal cavity. Arch Otolaryngol Head Neck 1999 (in press).
38. Asano K, Chee CBE, Gaston B, et al. Constitutive and inducible nitric oxide synthase gene expression, regulation and activity in human lung epithelium. Proc Natl Acad Sci U S A 1994; 91:10089-10093.
39. Watkins DN, Peroni DJ, Basclam KA, et al. Expression and activity of nitric oxide synthases in human airway epithelium. Am J Respir Cell Mol Biol 1997; 16:629-639.
40. Stoksted P. The physiologic cycle of the nose under normal and pathologic conditions. Acta Otolaryngol 1952; 42: 175-179.
41. Haight JSJ, Cole P. Nasal response to local unilateral stimuli in man. Rhinology 1983; 21:67-72.
42. Singh S, Evans TW, Nitric oxide, the biological mediator of the decade: fact or fiction? Eur Respir J 1997; 10:699-707.
43. Ali MY. Histology of the human nasopharyngeal mucosa. J Anat 1965; 99:657-672.
44. Gerlach H, Roissant R, Pappert D, et al. Autoinhalation of nitric oxide after endogenous synthesis in nasopharynx. Lancet 1994; 343:518-519.
45. Lundberg JON. Airborne nitric oxide: inflammatory marker and aerocrine messenger in man. Acta Physiol Scand 1996; Suppl 633:1-27.