Epigenetic regulation of spinal cord gene expression controls Opioid-Induced Hyperalgesia

Molecular Pain

Volumn 10, Issue 1, 2014, Pages

  Liang, De Yong ^a,b   Sun, Yuan ^a,b   Shi, Xiao You ^a,b   Sahbaie, Peyman ^a,b   Clark, J David ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

BDNF and dynorphin; Epigenetics; Histone acetylation; Opioid induced hyperalgesia

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIN DEPENDENT KINASE 5; DYNORPHIN A; GLIAL FIBRILLARY ACIDIC PROTEIN; HISTONE DEACETYLASE; HISTONE H3; KAPPA OPIATE RECEPTOR; MORPHINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; NEURON SPECIFIC NUCLEAR PROTEIN; PRODYNORPHIN; TRANSCRIPTION FACTOR FOSB; VORINOSTAT; ANA 12 COMPOUND; ANTINEOPLASTIC AGENT; AZEPINE DERIVATIVE; BENZAMIDE DERIVATIVE; DYNORPHIN; HYDROXAMIC ACID; NALTREXONE; NARCOTIC ANALGESIC AGENT; NARCOTIC ANTAGONIST; NORBINALTORPHIMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BDNF GENE; BEHAVIOR CHANGE; CAMK2A GENE; CDK5 GENE; CELLULAR DISTRIBUTION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG EXPOSURE; ENZYME INHIBITION; EPIGENETICS; EXON; FOSB GENE; GENE; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GRIN2A GENE; HISTONE ACETYLATION; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; OPIOID INDUCED HYPERALGESIA; PDYN GENE; PROMOTER REGION; PROTEIN EXPRESSION; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION; SPINAL CORD; SPINAL CORD DORSAL HORN; UPREGULATION; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DISEASE MODEL; DRUG EFFECTS; GENETIC EPIGENESIS; GENETICS; MALE; METABOLISM; PAIN MEASUREMENT; PATHOLOGY;

ANALGESICS, OPIOID; ANIMALS; ANTINEOPLASTIC AGENTS; AZEPINES; BENZAMIDES; BRAIN-DERIVED NEUROTROPHIC FACTOR; DISEASE MODELS, ANIMAL; DYNORPHINS; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION; HYDROXAMIC ACIDS; HYPERALGESIA; MALE; MICE; MICE, INBRED C57BL; MORPHINE; NALTREXONE; NARCOTIC ANTAGONISTS; PAIN MEASUREMENT; SPINAL CORD;

EID: 84907048241     PISSN: 17448069     EISSN: 17448069     Source Type: Journal    
DOI: 10.1186/1744-8069-10-59     Document Type: Article

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