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Volumn 49, Issue 2, 2013, Pages 312-319

Ethanol induces epigenetic modulation of prodynorphin and pronociceptin gene expression in the rat amygdala complex

Author keywords

Alcohol; Amygdala complex; Endogenous opioids; Epigenetic alterations

Indexed keywords

ALCOHOL; GENOMIC DNA; HISTONE H3; LYSINE; OPIATE PEPTIDE; PRODYNORPHIN; PRONOCICEPTIN; UNCLASSIFIED DRUG;

EID: 84875755372     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-012-9829-y     Document Type: Article
Times cited : (66)

References (57)
  • 2
    • 0036337759 scopus 로고    scopus 로고
    • Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosoes
    • 11740495 1:CAS:528:DC%2BD38XislGjsQ%3D%3D 10.1038/ng787
    • Boggs BA, Cheung P, Heard E et al (2002) Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosoes. Nat Genet 30:73-76
    • (2002) Nat Genet , vol.30 , pp. 73-76
    • Boggs, B.A.1    Cheung, P.2    Heard, E.3
  • 3
    • 13844250333 scopus 로고    scopus 로고
    • DNA hypermethylation of the alpha synuclein promoter in patients with alcoholism
    • DOI 10.1097/00001756-200502080-00020
    • Bönsch D, Lenz B, Kornhuber J, Bleich S (2005) DNA hypermethylation of the alpha synuclein promoter in patients with alcoholism. Neuroreport 16:167-170 (Pubitemid 40250393)
    • (2005) NeuroReport , vol.16 , Issue.2 , pp. 167-170
    • Bonsch, D.1    Lenz, B.2    Kornhuber, J.3    Bleich, S.4
  • 4
    • 75149183092 scopus 로고    scopus 로고
    • The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors
    • 19716811 1:CAS:528:DC%2BC3cXhtlelsL8%3D 10.1016/j.brainres.2009.08.062
    • Bruchas MR, Land BB, Chavkin C (2010) The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors. Brain Res 1314:44-55
    • (2010) Brain Res , vol.1314 , pp. 44-55
    • Bruchas, M.R.1    Land, B.B.2    Chavkin, C.3
  • 5
    • 84876100493 scopus 로고    scopus 로고
    • Different alcohol exposures induce selective alterations on the expression of dynorphin and nociceptin systems related genes in rat brain
    • doi: 10.1111/j.1369-1600.2011.00326.x
    • D'Addario C, Caputi FF, Rimondini R et al (2011a) Different alcohol exposures induce selective alterations on the expression of dynorphin and nociceptin systems related genes in rat brain. Addict Biol. doi: 10.1111/j.1369-1600.2011.00326.x
    • (2011) Addict Biol.
    • D'Addario, C.1    Caputi, F.F.2    Rimondini, R.3
  • 6
    • 79954571355 scopus 로고    scopus 로고
    • Ethanol and acetaldehyde exposure induces specific epigenetic modifications in the prodynorphin gene promoter in a human neuroblastoma cell line
    • 21106935 10.1096/fj.10-168534
    • D'Addario C, Johansson S, Candeletti S et al (2011b) Ethanol and acetaldehyde exposure induces specific epigenetic modifications in the prodynorphin gene promoter in a human neuroblastoma cell line. FASEB J 25:1069-1075
    • (2011) FASEB J , vol.25 , pp. 1069-1075
    • D'Addario, C.1    Johansson, S.2    Candeletti, S.3
  • 7
    • 34147171123 scopus 로고    scopus 로고
    • 2ChIP, a quick and quantitative chromatin immunoprecipitation assay, unravels epigenetic dynamics of developmentally regulated genes in human carcinoma cells
    • DOI 10.1634/stemcells.2006-0430
    • Dahl JA, Collas P (2007) Q2ChIP, a quick and quantitative chromatin immunoprecipitation assay, unravels epigenetic dynamics of developmentally regulated genes in human carcinoma cells. Stem Cells 25:1037-1046 (Pubitemid 46572602)
    • (2007) Stem Cells , vol.25 , Issue.4 , pp. 1037-1046
    • Dahl, J.A.1    Collas, P.2
  • 8
    • 46249110933 scopus 로고    scopus 로고
    • Dysregulation of nociceptin/orphanin FQ activity in the amygdala is linked to excessive alcohol drinking in the rat
    • 18367152 1:CAS:528:DC%2BD1cXosVyhu7Y%3D 10.1016/j.biopsych.2008.02.004
    • Economidou D, Hansson AC, Weiss F et al (2008) Dysregulation of nociceptin/orphanin FQ activity in the amygdala is linked to excessive alcohol drinking in the rat. Biol Psychiatry 64:211-218
    • (2008) Biol Psychiatry , vol.64 , pp. 211-218
    • Economidou, D.1    Hansson, A.C.2    Weiss, F.3
  • 9
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • DOI 10.1038/nature02625
    • Egger G, Liang G, Aparicio A, Jones PA (2004) Epigenetics in human disease and prospects for epigenetic therapy. Nature 429:457-463 (Pubitemid 38715140)
    • (2004) Nature , vol.429 , Issue.6990 , pp. 457-463
    • Egger, G.1    Liang, G.2    Aparicio, A.3    Jones, P.A.4
  • 10
    • 47149118525 scopus 로고    scopus 로고
    • DNA demethylation-dependent enhancement of Toll-like receptor-2 gene expression in cystic fibrosis epithelial cells involves SP1-activated transcription
    • 18423053 10.1186/1471-2199-9-39
    • Furuta T, Shuto T, Shimasaki S et al (2008) DNA demethylation-dependent enhancement of Toll-like receptor-2 gene expression in cystic fibrosis epithelial cells involves SP1-activated transcription. BMC Mol Biol 9:39
    • (2008) BMC Mol Biol , vol.9 , pp. 39
    • Furuta, T.1    Shuto, T.2    Shimasaki, S.3
  • 11
    • 0019875880 scopus 로고
    • Methylation of CpG sequences in eukaryotic DNA
    • 7215556 1:CAS:528:DyaL3MXhtFKhsrg%3D 10.1016/0014-5793(81)80055-5
    • Gruenbaum Y, Stein R, Cedar H, Razin A (1981) Methylation of CpG sequences in eukaryotic DNA. FEBS Lett 124:67-71
    • (1981) FEBS Lett , vol.124 , pp. 67-71
    • Gruenbaum, Y.1    Stein, R.2    Cedar, H.3    Razin, A.4
  • 12
    • 0030798245 scopus 로고    scopus 로고
    • Histone acetylation in chromatin structure and transcription
    • DOI 10.1038/38664
    • Grunstein M (1997) Histone acetylation in chromatin structure and transcription. Nature 389:349-352 (Pubitemid 27415209)
    • (1997) Nature , vol.389 , Issue.6649 , pp. 349-352
    • Grunstein, M.1
  • 13
    • 0024003456 scopus 로고
    • A direct link between core histone acetylation and transcriptionally active chromatin
    • 3409869 1:CAS:528:DyaL1cXktFyqtrc%3D
    • Hebbes TR, Thorne AW, Crane-Robinson C (1988) A direct link between core histone acetylation and transcriptionally active chromatin. EMBO J 7:1395-1402
    • (1988) EMBO J , vol.7 , pp. 1395-1402
    • Hebbes, T.R.1    Thorne, A.W.2    Crane-Robinson, C.3
  • 14
    • 58149353008 scopus 로고    scopus 로고
    • Promoter specific methylation of the dopamine transporter gene is altered in alcohol dependence and associated with craving
    • 18504048 10.1016/j.jpsychires.2008.04.006
    • Hillemacher T, Frieling H, Hartl T et al (2009) Promoter specific methylation of the dopamine transporter gene is altered in alcohol dependence and associated with craving. J Psychiatr Res 43:388-392
    • (2009) J Psychiatr Res , vol.43 , pp. 388-392
    • Hillemacher, T.1    Frieling, H.2    Hartl, T.3
  • 15
    • 0028106737 scopus 로고
    • Dependence of transcriptional repression on CpG methylation density
    • 7518564 1:CAS:528:DyaK2cXlsFSgu7k%3D
    • Hsieh CL (1994) Dependence of transcriptional repression on CpG methylation density. Mol Cell Biol 14:5487-5494
    • (1994) Mol Cell Biol , vol.14 , pp. 5487-5494
    • Hsieh, C.L.1
  • 16
    • 27544454705 scopus 로고    scopus 로고
    • Chromatin remodeling in neural development and plasticity
    • DOI 10.1016/j.ceb.2005.09.002, PII S0955067405001419
    • Hsieh J, Gage FH (2005) Chromatin remodeling in neural development and plasticity. Curr Opin Cell Biol 17:664-671 (Pubitemid 41540418)
    • (2005) Current Opinion in Cell Biology , vol.17 , Issue.6 , pp. 664-671
    • Hsieh, J.1    Gage, F.H.2
  • 17
    • 0033653176 scopus 로고    scopus 로고
    • OrphaninFQ: Role in behavioral fear responses and vulnerability to stress?
    • 11126386 1:CAS:528:DC%2BD3cXosFSgsrs%3D 10.1038/sj.mp.4000793
    • Jenck F, Ouagazzal AM, Pauly-Evers M, Moreau JL (2000) OrphaninFQ: role in behavioral fear responses and vulnerability to stress? Mol Psychiatry 5:572-574
    • (2000) Mol Psychiatry , vol.5 , pp. 572-574
    • Jenck, F.1    Ouagazzal, A.M.2    Pauly-Evers, M.3    Moreau, J.L.4
  • 18
    • 1642578909 scopus 로고    scopus 로고
    • Tonic inhibition by orphanin FQ/nociceptin of noradrenaline neurotransmission in the amygdala
    • DOI 10.1016/j.ejphar.2003.11.061
    • Kawahara Y, Hesselink MB, van Scharrenburg G, Westerink BH (2004) Tonic inhibition by orphanin FQ/nociceptin of noradrenaline neurotransmission in the amygdala. Eur J Pharmacol 485:197-200 (Pubitemid 38134415)
    • (2004) European Journal of Pharmacology , vol.485 , Issue.1-3 , pp. 197-200
    • Kawahara, Y.1    Hesselink, M.B.2    Van Scharrenburg, G.3    Westerink, B.H.C.4
  • 19
    • 33644978395 scopus 로고    scopus 로고
    • Acute in vivo effect of ethanol (binge drinking) on histone H3 modifications in rat tissues
    • 16314425 1:CAS:528:DC%2BD28XhvVeks7k%3D
    • Kim JS, Shukla SD (2006) Acute in vivo effect of ethanol (binge drinking) on histone H3 modifications in rat tissues. Alcohol Alcohol 41:126-132
    • (2006) Alcohol Alcohol , vol.41 , pp. 126-132
    • Kim, J.S.1    Shukla, S.D.2
  • 20
  • 21
    • 33746870694 scopus 로고    scopus 로고
    • The neurobiology of addiction: A neuroadaptational view relevant for diagnosis
    • DOI 10.1111/j.1360-0443.2006.01586.x
    • Koob GF (2006) The neurobiology of addiction: a neuroadaptational view relevant for diagnosis. Addiction 101:23-30 (Pubitemid 44199493)
    • (2006) Addiction , vol.101 , Issue.SUPPL. 1 , pp. 23-30
    • Koob, G.F.1
  • 23
    • 33947262606 scopus 로고    scopus 로고
    • The nociceptin/orphanin FQ receptor agonist Ro 64-6198 reduces alcohol self-administration and prevents relapse-like alcohol drinking
    • DOI 10.1038/sj.npp.1301169, PII 1301169
    • Kuzmin A, Kreek MJ, Bakalkin G et al (2007) The nociceptin/orphanin FQ receptor agonist Ro 64-6198 reduces alcohol self-administration and prevents relapse-like alcohol drinking. Neuropsychopharmacology 32:902-910 (Pubitemid 46426176)
    • (2007) Neuropsychopharmacology , vol.32 , Issue.4 , pp. 902-910
    • Kuzmin, A.1    Kreek, M.J.2    Bakalkin, G.3    Liljequist, S.4
  • 24
    • 0035282573 scopus 로고    scopus 로고
    • Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
    • DOI 10.1038/35065132
    • Lachner M, O' CD, Rea S et al (2001) Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 410:116-120 (Pubitemid 32225847)
    • (2001) Nature , vol.410 , Issue.6824 , pp. 116-120
    • Lachner, M.1    O'Carroll, D.2    Rea, S.3    Mechtler, K.4    Jenuwein, T.5
  • 25
    • 56349120585 scopus 로고    scopus 로고
    • Effects of acute ethanol on opioid peptide release in the central amygdala: An in vivo microdialysis study
    • 18688603 1:CAS:528:DC%2BD1cXhtlyjtLvI 10.1007/s00213-008-1267-8
    • Lam MP, Marinelli PW, Bai L, Gianoulakis C (2008) Effects of acute ethanol on opioid peptide release in the central amygdala: an in vivo microdialysis study. Psychopharmacology 201:261-271
    • (2008) Psychopharmacology , vol.201 , pp. 261-271
    • Lam, M.P.1    Marinelli, P.W.2    Bai, L.3    Gianoulakis, C.4
  • 26
    • 0036138829 scopus 로고    scopus 로고
    • Nociceptin/orphanin FQ tissue concentration in the rat brain. Effects of repeated ethanol administration at various post-treatment intervals
    • DOI 10.1016/S0278-5846(01)00270-6, PII S0278584601002706
    • Lindholm S, Ploj K, Franck J, Nylander I (2002) Nociceptin/orphanin FQ tissue concentration in the rat brain. Effects of repeated ethanol administration at various post-treatment intervals. Prog Neuropsychopharmacol Biol Psychiatry 26:303-306 (Pubitemid 34038058)
    • (2002) Progress in Neuro-Psychopharmacology and Biological Psychiatry , vol.26 , Issue.2 , pp. 303-306
    • Lindholm, S.1    Ploj, K.2    Franck, J.3    Nylander, I.4
  • 27
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25:402-408 (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 28
    • 0035043217 scopus 로고    scopus 로고
    • Quantification of HER2/neu gene amplification by competitive PCR using fluorescent melting curve analysis
    • Lyon E, Millson A, Lowery MC et al (2001) Quantificationof HER2/neu gene amplification by competitive PCR using fluorescent melting curve analysis. Clin Chem 47:844-851 (Pubitemid 32398035)
    • (2001) Clinical Chemistry , vol.47 , Issue.5 , pp. 844-851
    • Lyon, E.1    Millson, A.2    Lowery, M.C.3    Woods, R.4    Wittwer, C.T.5
  • 29
    • 82355175410 scopus 로고    scopus 로고
    • Histone deacetylase and mood disorders: Epigenetic programming in gene-environment interactions
    • 20961400 1:CAS:528:DC%2BC38XnsVGitQ%3D%3D 10.1111/j.1755-5949.2010.00203. x
    • Machado-Vieira R, Ibrahim L, Zarate CA Jr (2011) histone deacetylase and mood disorders: epigenetic programming in gene-environment interactions. CNS Neurosci Ther 17:699-704
    • (2011) CNS Neurosci Ther , vol.17 , pp. 699-704
    • Machado-Vieira, R.1    Ibrahim, L.2    Zarate, Jr.C.A.3
  • 30
    • 53349098906 scopus 로고    scopus 로고
    • Epegenomics: A roadmap, but to where?
    • 18832628 1:CAS:528:DC%2BD1cXht1GmsrjP 10.1126/science.322.5898.43b
    • Madhani HD, Francis NJ, Kingston RE et al (2008) Epegenomics: a roadmap, but to where? Science 322:43-44
    • (2008) Science , vol.322 , pp. 43-44
    • Madhani, H.D.1    Francis, N.J.2    Kingston, R.E.3
  • 31
    • 0031903999 scopus 로고    scopus 로고
    • Effect of ethanol on chromatin and nonhistone nuclear proteins in rat brain
    • DOI 10.1023/A:1020778018149
    • Mahadev K, Vemuri MC (1998) Effect of ethanol on chromatin and nonhistone nuclear proteins in rat brain. Neurochem Res 23:1179-1184 (Pubitemid 28363591)
    • (1998) Neurochemical Research , vol.23 , Issue.9 , pp. 1179-1184
    • Mahadev, K.1    Vemuri, M.C.2
  • 32
    • 0034850298 scopus 로고    scopus 로고
    • The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family
    • Mogil JS, Pasternak GW (2001) The molecular and behavioural pharmacology of the orphanin FQ/nociceptin peptide and receptor family. Pharmacol Rev 53:381-415 (Pubitemid 32852018)
    • (2001) Pharmacological Reviews , vol.53 , Issue.3 , pp. 381-415
    • Mogil, J.S.1    Pasternak, G.W.2
  • 33
    • 2442658861 scopus 로고    scopus 로고
    • Opioids and alcoholism
    • DOI 10.1016/j.physbeh.2004.02.008, PII S0031938404000514
    • Oswald LM, Wand GS (2004) Opioids and alcoholism. Physiol Behav 81:339-358 (Pubitemid 38670094)
    • (2004) Physiology and Behavior , vol.81 , Issue.2 , pp. 339-358
    • Oswald, L.M.1    Wand, G.S.2
  • 34
    • 34548527262 scopus 로고    scopus 로고
    • Distinct methylation patterns in histone H3 at Lys-4 and Lys-9 correlate with up- & down-regulation of genes by ethanol in hepatocytes
    • DOI 10.1016/j.lfs.2007.07.030, PII S0024320507005322
    • Pal-Bhadra M, Bhadra U, Jackson DE et al (2007) Distinct methylation patterns in histone H3 at Lys-4 and Lys-9 correlate with up- & down-regulation of genes by ethanol in hepatocytes. Life Sci 81:979-987 (Pubitemid 47384784)
    • (2007) Life Sciences , vol.81 , Issue.12 , pp. 979-987
    • Pal-Bhadra, M.1    Bhadra, U.2    Jackson, D.E.3    Mamatha, L.4    Park, P.-H.5    Shukla, S.D.6
  • 35
    • 33748131853 scopus 로고    scopus 로고
    • Central and medial amygdaloid brain-derived neurotrophic factor signaling plays a critical role in alcohol-drinking and anxiety-like behaviors
    • DOI 10.1523/JNEUROSCI.4988-05.2006
    • Pandey SC, Zhang H, Roy A et al (2006) Central and medial amygdaloid brain-derived neurotrophic factor signaling plays a critical role in alcohol-drinking and anxiety-like behaviors. J Neurosci 26:8320-8331 (Pubitemid 44309846)
    • (2006) Journal of Neuroscience , vol.26 , Issue.32 , pp. 8320-8331
    • Pandey, S.C.1    Zhang, H.2    Roy, A.3    Misra, K.4
  • 36
    • 43649105135 scopus 로고    scopus 로고
    • Brain chromatin remodeling: A novel mechanism of alcoholism
    • 18385331 1:CAS:528:DC%2BD1cXkslSjtb0%3D 10.1523/JNEUROSCI.5731-07.2008
    • Pandey SC, Ugale R, Zhang H et al (2008) Brain chromatin remodeling: a novel mechanism of alcoholism. J Neurosci 28:3729-3737
    • (2008) J Neurosci , vol.28 , pp. 3729-3737
    • Pandey, S.C.1    Ugale, R.2    Zhang, H.3
  • 38
    • 0019293220 scopus 로고
    • AChE-stained horizontal sections of the rat brain in stereotaxis coordinates
    • DOI 10.1016/0165-0270(80)90021-7
    • Paxinos G, Watson CR, Emson PC (1980) AChE-stained horizontal sections of the rat brain in stereotaxic coordinates. J Neurosci Methods 3:129-149 (Pubitemid 11162950)
    • (1980) Journal of Neuroscience Methods , vol.3 , Issue.2 , pp. 129-149
    • Paxinos, G.1    Watson, C.2    Emson, P.C.3
  • 39
    • 0036338205 scopus 로고    scopus 로고
    • Histone H3 lisyne 9 methylation is an epigenetic imprint of facultative heterochromatin
    • 11740497 1:CAS:528:DC%2BD38XivVCrsQ%3D%3D 10.1038/ng789
    • Peters AH, Mermoud JE, O'Carroll D et al (2002) Histone H3 lisyne 9 methylation is an epigenetic imprint of facultative heterochromatin. Nat Genet 30:77-80
    • (2002) Nat Genet , vol.30 , pp. 77-80
    • Peters, A.H.1    Mermoud, J.E.2    O'Carroll, D.3
  • 40
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • 11328886 1:STN:280:DC%2BD38nis12jtw%3D%3D 10.1093/nar/29.9.e45
    • Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29:e45
    • (2001) Nucleic Acids Res , vol.29 , pp. 45
    • Pfaffl, M.W.1
  • 41
    • 0035542548 scopus 로고    scopus 로고
    • Transcription initiation: Imposing specificity by localization
    • Ptashne M, Gann A (2001) Transcription initiation: imposing specificity by localization. Essays Biochem 37:1-15 (Pubitemid 33402952)
    • (2001) Essays in Biochemistry , vol.37 , pp. 1-15
    • Ptashne, M.1    Gann, A.2
  • 42
    • 67549083119 scopus 로고    scopus 로고
    • Histone acetylation in drug addiction
    • 19560043 1:CAS:528:DC%2BD1MXnslyrtLk%3D 10.1016/j.semcdb.2009.01.005
    • Renthal W, Nestler EJ (2009) Histone acetylation in drug addiction. Semin Cell Dev Biol 20:387-394
    • (2009) Semin Cell Dev Biol , vol.20 , pp. 387-394
    • Renthal, W.1    Nestler, E.J.2
  • 43
    • 65549142573 scopus 로고    scopus 로고
    • Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins
    • 19447090 1:CAS:528:DC%2BD1MXmsFWjt7c%3D 10.1016/j.neuron.2009.03.026
    • Renthal W, Kumar A, Xiao G et al (2009) Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins. Neuron 62:335-348
    • (2009) Neuron , vol.62 , pp. 335-348
    • Renthal, W.1    Kumar, A.2    Xiao, G.3
  • 44
    • 0033990048 scopus 로고    scopus 로고
    • Primer3 on the WWW for general users and for biologist programmers
    • S. Krawetz S. Misener (eds) Humana Press New York
    • Rozen S, Skaletsky HJ (2000) Primer3 on the WWW for general users and for biologist programmers. In: Krawetz S, Misener S (eds) Bioinformatics methods and protocols: methods in molecular biology. Humana Press, New York, pp 365-386
    • (2000) Bioinformatics Methods and Protocols: Methods in Molecular Biology , pp. 365-386
    • Rozen, S.1    Skaletsky, H.J.2
  • 45
    • 33749394256 scopus 로고    scopus 로고
    • Epigenetic effects of ethanol on liver and gastrointestinal injury
    • Shukla SD, Aroor AR (2006) Epigenetic effects of ethanol on liver and gastrointestinal injury. World J Gastroenterol 12:5265-5271 (Pubitemid 44501767)
    • (2006) World Journal of Gastroenterology , vol.12 , Issue.33 , pp. 5265-5271
    • Shukla, S.D.1    Aroor, A.R.2
  • 46
    • 84856524861 scopus 로고    scopus 로고
    • Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy
    • 21725353
    • Spiegel S, Milstien S, Grant S (2011) Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy. Oncogene 31:537-551
    • (2011) Oncogene , vol.31 , pp. 537-551
    • Spiegel, S.1    Milstien, S.2    Grant, S.3
  • 47
    • 79953191540 scopus 로고    scopus 로고
    • Prodynorphin CpG-SNPs associated with alcohol dependence: Elevated methylation in the brain of human alcoholics
    • 21521424 1:CAS:528:DC%2BC3MXpvVWqt78%3D 10.1111/j.1369-1600.2011.00323.x
    • Taqi MM, Bazov I, Watanabe H et al (2011) Prodynorphin CpG-SNPs associated with alcohol dependence: elevated methylation in the brain of human alcoholics. Addict Biol 16:499-509
    • (2011) Addict Biol , vol.16 , pp. 499-509
    • Taqi, M.M.1    Bazov, I.2    Watanabe, H.3
  • 48
    • 0036850325 scopus 로고    scopus 로고
    • Cellular memory and the histone code
    • DOI 10.1016/S0092-8674(02)01080-2
    • Turner BM (2002) Cellular memory and the histone code. Cell 111:285-291 (Pubitemid 35341385)
    • (2002) Cell , vol.111 , Issue.3 , pp. 285-291
    • Turner, B.M.1
  • 49
    • 24744433805 scopus 로고    scopus 로고
    • Role of histone acetylation in the control of gene expression
    • DOI 10.1139/o05-041
    • Verdone L, Caserta M, Di Mauro E (2005) Role of histone acetylation in the control of gene expression. Biochem Cell Biol 83:344-353 (Pubitemid 41297202)
    • (2005) Biochemistry and Cell Biology , vol.83 , Issue.3 , pp. 344-353
    • Verdone, L.1    Caserta, M.2    Di Mauro, E.3
  • 50
    • 38149072294 scopus 로고    scopus 로고
    • Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence
    • 17473837 1:CAS:528:DC%2BD1cXmsFSmug%3D%3D 10.1038/sj.npp.1301438
    • Walker BM, Koob GF (2008) Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence. Neuropsychopharmacology 33:643-652
    • (2008) Neuropsychopharmacology , vol.33 , pp. 643-652
    • Walker, B.M.1    Koob, G.F.2
  • 51
    • 78649910013 scopus 로고    scopus 로고
    • Systemic kappa-opioid receptor antagonism by nor-binaltorphimine reduces dependence-induced excessive alcohol self-administration in rats
    • 20579007 1:CAS:528:DC%2BC3MXmvVequw%3D%3D 10.1111/j.1369-1600.2010.00226. x
    • Walker BM, Zorrilla EP, Koob GF (2011) Systemic kappa-opioid receptor antagonism by nor-binaltorphimine reduces dependence-induced excessive alcohol self-administration in rats. Addict Biol 16:116-119
    • (2011) Addict Biol , vol.16 , pp. 116-119
    • Walker, B.M.1    Zorrilla, E.P.2    Koob, G.F.3
  • 53
    • 77953290684 scopus 로고    scopus 로고
    • The role of the dynorphin-kappa opioid system in the reinforcing effects of drugs of abuse
    • 20352414 1:CAS:528:DC%2BC3cXjvFKqt7c%3D 10.1007/s00213-010-1825-8
    • Wee S, Koob GF (2010) The role of the dynorphin-kappa opioid system in the reinforcing effects of drugs of abuse. Psychopharmacology 210:121-135
    • (2010) Psychopharmacology , vol.210 , pp. 121-135
    • Wee, S.1    Koob, G.F.2
  • 54
    • 23844520882 scopus 로고    scopus 로고
    • Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis
    • DOI 10.1016/j.ajog.2005.01.034, PII S0002937805001110
    • Wu Y, Halverson G, Basir Z et al (2005) Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis. Am J Obstet Gynecol 193:371-380 (Pubitemid 41159530)
    • (2005) American Journal of Obstetrics and Gynecology , vol.193 , Issue.2 , pp. 371-380
    • Wu, Y.1    Halverson, G.2    Basir, Z.3    Strawn, E.4    Yan, P.5    Guo, S.-W.6
  • 55
    • 0037023681 scopus 로고    scopus 로고
    • Histone H3 lysine 4 methylation disrupts binding of nucleosome remodeling and deacetylase (NuRD) repressor complex
    • DOI 10.1074/jbc.C200045200
    • Zegerman P, Canas B, Pappin D, Kouzarides T (2002) Histone H3 lysine 4 methylation disrupts binding of nucleosome remodeling and deacetylase (NuRD) repressor complex. J Biol Chem 277:11621-11624 (Pubitemid 34952711)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.14 , pp. 11621-11624
    • Zegerman, P.1    Canas, B.2    Pappin, D.3    Kouzarides, T.4
  • 56
    • 0033777377 scopus 로고    scopus 로고
    • Reduced hypothalamic POMC and anterior pituitary CRF1 receptor mRNA levels after acute, but not chronic, daily "binge" intragastric alcohol administration
    • 11045867 1:CAS:528:DC%2BD3cXnvV2gtrc%3D
    • Zhou Y, Franck J, Spangler R et al (2000) Reduced hypothalamic POMC and anterior pituitary CRF1 receptor mRNA levels after acute, but not chronic, daily "binge" intragastric alcohol administration. Alcohol Clin Exp Res 24:1575-1582
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 1575-1582
    • Zhou, Y.1    Franck, J.2    Spangler, R.3
  • 57
    • 79955583858 scopus 로고    scopus 로고
    • Substance-specific and shared transcription and epigenetic changes in the human hippocampus chronically exposed to cocaine and alcohol
    • 21464311 1:CAS:528:DC%2BC3MXlt1Grs7c%3D 10.1073/pnas.1018514108
    • Zhou Z, Yuan Q, Mash DC, Goldman D (2011) Substance-specific and shared transcription and epigenetic changes in the human hippocampus chronically exposed to cocaine and alcohol. Proc Natl Acad Sci USA 108:6626-6631
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 6626-6631
    • Zhou, Z.1    Yuan, Q.2    Mash, D.C.3    Goldman, D.4


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