메뉴 건너뛰기




Volumn 90, Issue 9, 2014, Pages 790-798

Cellular response of the rat brain to single doses of 137Cs γ rays does not predict its response to prolonged 'biologically equivalent' fractionated doses

Author keywords

Brain irradiation; Fractionated dose responses; Inflammation; Neurogenesis; Single dose responses

Indexed keywords

CESIUM 137; CESIUM;

EID: 84907045262     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.3109/09553002.2014.933915     Document Type: Article
Times cited : (13)

References (78)
  • 2
    • 0027490317 scopus 로고
    • Radiation-induced astrocytic and microglial responses in mouse brain
    • Chiang CS , McBride WH, Withers HR . 1993. Radiation-induced astrocytic and microglial responses in mouse brain . Radiother Oncol 29 : 60-68 .
    • (1993) Radiother Oncol , vol.29 , pp. 60-68
    • Chiang, C.S.1    McBride, W.H.2    Withers, H.R.3
  • 3
    • 73349128110 scopus 로고    scopus 로고
    • Effects of the AT1 receptor antagonist L-158,809 on microglia and neurogenesis after fractionated whole-brain irradiation
    • Conner KR , Payne VS , Forbes ME , Robbins ME , Riddle DR . 2010 . Effects of the AT1 receptor antagonist L-158,809 on microglia and neurogenesis after fractionated whole-brain irradiation . Radiat Res 173 : 49-61 .
    • (2010) Radiat Res , vol.173 , pp. 49-61
    • Conner, K.R.1    Payne, V.S.2    Forbes, M.E.3    Robbins, M.E.4    Riddle, D.R.5
  • 4
    • 0028356814 scopus 로고
    • Neurobehavioral sequelae of cranial irradiation in adults: A review of radiationinduced encephalopathy
    • Crossen JR , Garwood D , Glatstein E , Neuwelt EA . 1994 . Neurobehavioral sequelae of cranial irradiation in adults: A review of radiationinduced encephalopathy . J Clin Oncol 12 : 627-642 .
    • (1994) J Clin Oncol , vol.12 , pp. 627-642
    • Crossen, J.R.1    Garwood, D.2    Glatstein, E.3    Neuwelt, E.A.4
  • 5
  • 7
    • 0025935469 scopus 로고
    • Central nervous system injury by therapeutic irradiation
    • Dropcho EJ . 1991. Central nervous system injury by therapeutic irradiation . Neurol Clin 9 : 969-988 .
    • (1991) Neurol Clin , vol.9 , pp. 969-988
    • Dropcho, E.J.1
  • 8
    • 5344232095 scopus 로고    scopus 로고
    • Hippocampus: Cognitive processes and neural representations that underlie declarative memory
    • Eichenbaum H . 2004. Hippocampus: Cognitive processes and neural representations that underlie declarative memory . Neuron 44 : 109-120 .
    • (2004) Neuron , vol.44 , pp. 109-120
    • Eichenbaum, H.1
  • 9
    • 0035861386 scopus 로고    scopus 로고
    • The hippocampus and declarative memory: Cognitive mechanisms and neural codes
    • Eichenbaum H . 2001 . The hippocampus and declarative memory: Cognitive mechanisms and neural codes . Behav Brain Res 127 : 199-207 .
    • (2001) Behav Brain Res , vol.127 , pp. 199-207
    • Eichenbaum, H.1
  • 10
    • 0029972857 scopus 로고    scopus 로고
    • Brain microglia/ macrophages express neurotrophins that selectively regulate microglial proliferation and function
    • Elkabes S , DiCicco-Bloom EM , Black IB . 1996 . Brain microglia/ macrophages express neurotrophins that selectively regulate microglial proliferation and function . J Neurosci 16 : 2508-2521 .
    • (1996) J Neurosci , vol.16 , pp. 2508-2521
    • Elkabes, S.1    Dicicco-Bloom, E.M.2    Black, I.B.3
  • 12
    • 0024358259 scopus 로고
    • The linear-quadratic formula and progress in fractionated radiotherapy
    • Fowler JF . 1989 . The linear-quadratic formula and progress in fractionated radiotherapy. Br J Radiol 62: 679-694.
    • (1989) Br J Radiol , vol.62 , pp. 679-694
    • Fowler, J.F.1
  • 13
    • 0042170274 scopus 로고    scopus 로고
    • Differences in ICAM-1 and TNF-alpha expression between large single fraction and fractionated irradiation in mouse brain
    • Gaber MW, Sabek OM, Fukatsu K , Wilcox HG , Kiani MF , Merchant TE . 2003 . Differences in ICAM-1 and TNF-alpha expression between large single fraction and fractionated irradiation in mouse brain . Int J Radiat Biol 79: 359-366.
    • (2003) Int J Radiat Biol , vol.79 , pp. 359-366
    • Gaber, M.W.1    Sabek, O.M.2    Fukatsu, K.3    Wilcox, H.G.4    Kiani, M.F.5    Merchant, T.E.6
  • 15
    • 0035399785 scopus 로고    scopus 로고
    • Microglia in neurodegeneration: Molecular aspects
    • Gebicke-Haerter PJ . 2001 . Microglia in neurodegeneration: molecular aspects . Microsc Res Tech 54 : 47-58 .
    • (2001) Microsc Res Tech , vol.54 , pp. 47-58
    • Gebicke-Haerter, P.J.1
  • 16
    • 0031975026 scopus 로고    scopus 로고
    • Response of postmitotic neurons to X-irradiation: Implications for the role of DNA damage in neuronal apoptosis
    • Gobbel GT , Bellinzona M, Vogt AR, Gupta N , Fike JR, Chan PH . 1998. Response of postmitotic neurons to X-irradiation: Implications for the role of DNA damage in neuronal apoptosis . J Neurosci 18: 147-155.
    • (1998) J Neurosci , vol.18 , pp. 147-155
    • Gobbel, G.T.1    Bellinzona, M.2    Vogt, A.R.3    Gupta, N.4    Fike, J.R.5    Chan, P.H.6
  • 19
    • 0033045425 scopus 로고    scopus 로고
    • The effi ciency of systematic sampling in stereology-reconsidered
    • Gundersen HJG , Jensen EBV , Kieu K , Nielsen J . 1999. The effi ciency of systematic sampling in stereology-reconsidered . J Microscopy 193 : 199-211 .
    • (1999) J Microscopy , vol.193 , pp. 199-211
    • Hjg, G.1    Ebv, J.2    Kieu, K.3    Nielsen, J.4
  • 20
    • 0003096708 scopus 로고    scopus 로고
    • Time, dose, and fractionation in radiotherapy
    • 7th ed . Philadelphia Lippincott, Williams and Wilkins
    • Hall EJ , Giaccia AJ . 2012. Time, dose, and fractionation in radiotherapy. In: Radiobiology for the radiologist , 7th ed . Philadelphia: Lippincott, Williams and Wilkins , p. 405 .
    • (2012) Radiobiology for the Radiologist , pp. 405
    • Hall, E.J.1    Giaccia, A.J.2
  • 21
    • 35548986304 scopus 로고    scopus 로고
    • Microglia: Active sensor and versatile eff ector cells in the normal and pathologic brain
    • Hanisch UK , Kettenmann H . 2007. Microglia: Active sensor and versatile eff ector cells in the normal and pathologic brain . Nat Neurosci 10 : 1387-1394 .
    • (2007) Nat Neurosci , vol.10 , pp. 1387-1394
    • Hanisch, U.K.1    Kettenmann, H.2
  • 22
    • 0033515604 scopus 로고    scopus 로고
    • Insulin-like growth factor-1-mediated neuroprotection against oxidative stress is associated with activation of nuclear factor ě B
    • Heck S , Lezoualc ' H F , Engert S , Behl C . 1999. Insulin-like growth factor-1-mediated neuroprotection against oxidative stress is associated with activation of nuclear factor ě B . J Biolog Chem 274 : 9828-9835 .
    • (1999) J Biolog Chem , vol.274 , pp. 9828-9835
    • Heck, S.1    Lezoualc, H.F.2    Engert, S.3    Behl, C.4
  • 24
    • 84871572292 scopus 로고    scopus 로고
    • Regionally distinct responses of microglia and glial progenitor cells to whole brain irradiation in adult and aging rats
    • Hua K , Schindler MK , McQuail JA , Forbes ME , Riddle DR . 2012 . Regionally distinct responses of microglia and glial progenitor cells to whole brain irradiation in adult and aging rats . PLoS One 7 : e52728 .
    • (2012) PLoS One , vol.7 , pp. e52728
    • Hua, K.1    Schindler, M.K.2    McQuail, J.A.3    Forbes, M.E.4    Riddle, D.R.5
  • 28
    • 33644850757 scopus 로고    scopus 로고
    • Whole-brain radiotherapy in the management of brain metastasis
    • Khuntia D , Brown P , Li J , Mehta MP . 2006. Whole-brain radiotherapy in the management of brain metastasis . J Clin Oncol 24 : 1295-1304 .
    • (2006) J Clin Oncol , vol.24 , pp. 1295-1304
    • Khuntia, D.1    Brown, P.2    Li, J.3    Mehta, M.P.4
  • 29
    • 25444495866 scopus 로고    scopus 로고
    • Microglia in health and disease
    • Kim SU , de Vellis J . 2005 . Microglia in health and disease . J Neurosci Res 81: 302-313.
    • (2005) J Neurosci Res , vol.81 , pp. 302-313
    • Kim, S.U.1    De Vellis, J.2
  • 31
    • 84864449051 scopus 로고    scopus 로고
    • Cross-talk between neural stem cells and immune cells: The key to better brain repair [quest]
    • Kokaia Z , Martino G , Schwartz M , Lindvall O . 2012 . Cross-talk between neural stem cells and immune cells: The key to better brain repair [quest] . Nature Neurosci 15 : 1078-1087 .
    • (2012) Nature Neurosci , vol.15 , pp. 1078-1087
    • Kokaia, Z.1    Martino, G.2    Schwartz, M.3    Lindvall, O.4
  • 34
    • 84864445722 scopus 로고    scopus 로고
    • Chronic administration of the Angiotensin-converting enzyme inhibitor, ramipril, prevents fractionated whole-brain irradiationinduced perirhinal cortex-dependent cognitive impairment
    • Lee TC , Greene-Schloesser D , Payne V , Diz DI , Hsu FC , Kooshki M , Mustafa R , Riddle DR , Zhao W , Chan MD , Robbins ME . 2012 . Chronic administration of the Angiotensin-converting enzyme inhibitor, ramipril, prevents fractionated whole-brain irradiationinduced perirhinal cortex-dependent cognitive impairment . Radiat Res 178: 46-56.
    • (2012) Radiat Res , vol.178 , pp. 46-56
    • Lee, T.C.1    Greene-Schloesser, D.2    Payne, V.3    Diz, D.I.4    Hsu, F.C.5    Kooshki, M.6    Mustafa, R.7    Riddle, D.R.8    Zhao, W.9    Chan, M.D.10    Robbins, M.E.11
  • 35
    • 77249171256 scopus 로고    scopus 로고
    • Irradiation induces regionally specifi c alterations in pro-infl ammatory environments in rat brain
    • Lee WH , Sonntag WE , Mitschelen M , Yan H , Lee YW . 2010 . Irradiation induces regionally specifi c alterations in pro-infl ammatory environments in rat brain. Int J Radiat Biol 86: 132-144.
    • (2010) Int J Radiat Biol , vol.86 , pp. 132-144
    • Lee, W.H.1    Sonntag, W.E.2    Mitschelen, M.3    Yan, H.4    Lee, Y.W.5
  • 37
    • 33845973382 scopus 로고    scopus 로고
    • Radiation-induced cognitive dysfunction and cerebellar oxidative stress in mice: Protective eff ect of á -lipoic acid
    • Manda K , Ueno M , Moritake T , Anzai K . 2007 . Radiation-induced cognitive dysfunction and cerebellar oxidative stress in mice: Protective eff ect of á -lipoic acid. Behav Brain Res 177: 7-14.
    • (2007) Behav Brain Res , vol.177 , pp. 7-14
    • Manda, K.1    Ueno, M.2    Moritake, T.3    Anzai, K.4
  • 38
    • 0030611750 scopus 로고    scopus 로고
    • Activation of NF- ě B protects hippocampal neurons against oxidative stressinduced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration
    • Mattson MP , Goodman Y , Luo H, Fu W, Furukawa K . 1997. Activation of NF- ě B protects hippocampal neurons against oxidative stressinduced apoptosis: Evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration . J Neurosci Res 49 : 681-697 .
    • (1997) J Neurosci Res , vol.49 , pp. 681-697
    • Mattson, M.P.1    Goodman, Y.2    Luo, H.3    Fu, W.4    Furukawa, K.5
  • 40
    • 0036735783 scopus 로고    scopus 로고
    • Irradiation induces neural precursor-cell dysfunction
    • Monje ML , Mizumatsu S , Fike JR, Palmer TD . 2002. Irradiation induces neural precursor-cell dysfunction . Nat Med 8 : 955-962 .
    • (2002) Nat Med , vol.8 , pp. 955-962
    • Monje, M.L.1    Mizumatsu, S.2    Fike, J.R.3    Palmer, T.D.4
  • 41
    • 0345189366 scopus 로고    scopus 로고
    • Infl ammatory blockade restores adult hippocampal neurogenesis
    • Monje ML , Toda H , Palmer TD . 2003 . Infl ammatory blockade restores adult hippocampal neurogenesis . Science 302: 1760-1765.
    • (2003) Science , vol.302 , pp. 1760-1765
    • Monje, M.L.1    Toda, H.2    Palmer, T.D.3
  • 42
    • 37349127393 scopus 로고    scopus 로고
    • Impaired human hippocampal neurogenesis after treatment for central nervous system malignancies
    • Monje ML , Vogel H , Masek M , Ligon KL , Fisher PG , Palmer TD . 2007 . Impaired human hippocampal neurogenesis after treatment for central nervous system malignancies . Ann Neurol 62 : 515-520 .
    • (2007) Ann Neurol , vol.62 , pp. 515-520
    • Monje, M.L.1    Vogel, H.2    Masek, M.3    Ligon, K.L.4    Fisher, P.G.5    Palmer, T.D.6
  • 43
    • 84907047492 scopus 로고    scopus 로고
    • Changes in hippocampal gene expression 48 hours and 2 months after fractionated whole-brain irradiation of the young adult male rat
    • POS27-16
    • Moore E , Schloesser D , Miller L , Robbins M . 2011 . Changes in hippocampal gene expression 48 hours and 2 months after fractionated whole-brain irradiation of the young adult male rat . 14th International Congress of Radiation Research , POS27-16 .
    • (2011) 14th International Congress of Radiation Research
    • Moore, E.1    Schloesser, D.2    Miller, L.3    Robbins, M.4
  • 44
    • 85006538083 scopus 로고    scopus 로고
    • Diff erential expression of Homer1a in the hippocampus and cortex likely plays a role in radiation-induced brain injury
    • Moore ED , Kooshki M , Wheeler KT , Metheny-Barlow LJ , Robbins ME . 2013 . Diff erential expression of Homer1a in the hippocampus and cortex likely plays a role in radiation-induced brain injury . Radiat Res .
    • (2013) Radiat Res
    • Moore, E.D.1    Kooshki, M.2    Wheeler, K.T.3    Metheny-Barlow, L.J.4    Robbins, M.E.5
  • 45
    • 80053255939 scopus 로고    scopus 로고
    • Cranial irradiation leads to acute and persistent neuroinfl ammation with delayed increases in T-cell infi ltration and CD11c expression in C57BL/6 mouse brain
    • Moravan MJ , Olschowka JA , Williams JP , O ' Banion MK . 2011. Cranial irradiation leads to acute and persistent neuroinfl ammation with delayed increases in T-cell infi ltration and CD11c expression in C57BL/6 mouse brain. Radiat Res 176: 459-473.
    • (2011) Radiat Res , vol.176 , pp. 459-473
    • Moravan, M.J.1    Olschowka, J.A.2    Williams, J.P.3    O'Banion, M.K.4
  • 46
    • 0031795274 scopus 로고    scopus 로고
    • Basic fi broblast growth factor: A potential therapeutic agent for the treatment of acute neurodegenerative disorders and vascular insuffi ciency
    • Moyer JA , Wood A , Zaleska MM , Ay I , Finklestein SP , Protter AA . 1998 . Basic fi broblast growth factor: A potential therapeutic agent for the treatment of acute neurodegenerative disorders and vascular insuffi ciency . Expert Opin Th erapeut Patents 8: 1425-1445 .
    • (1998) Expert Opin Th Erapeut Patents , vol.8 , pp. 1425-1445
    • Moyer, J.A.1    Wood, A.2    Zaleska, M.M.3    Ay, I.4    Finklestein, S.P.5    Protter, A.A.6
  • 47
    • 0033509599 scopus 로고    scopus 로고
    • Late radiation toxicity after whole brain radiotherapy: The infl uence of antiepileptic drugs
    • Nieder C , Leicht A , Motaref B , Nestle U , Niewald M , Schnabel K . 1999 . Late radiation toxicity after whole brain radiotherapy: The infl uence of antiepileptic drugs . Am J Clin Oncol 22 : 573-579 .
    • (1999) Am J Clin Oncol , vol.22 , pp. 573-579
    • Nieder, C.1    Leicht, A.2    Motaref, B.3    Nestle, U.4    Niewald, M.5    Schnabel, K.6
  • 48
    • 33748474549 scopus 로고    scopus 로고
    • Activation of antioxidative enzymes induced by low-dose-rate whole-body ã irradiation: Adaptive response in terms of initial DNA damage
    • Otsuka K , Koana T , Tauchi H, Sakai K . 2006. Activation of antioxidative enzymes induced by low-dose-rate whole-body ã irradiation: Adaptive response in terms of initial DNA damage . Radiat Res 166 : 474-478 .
    • (2006) Radiat Res , vol.166 , pp. 474-478
    • Otsuka, K.1    Koana, T.2    Tauchi, H.3    Sakai, K.4
  • 49
    • 0034597430 scopus 로고    scopus 로고
    • Vascular niche for adult hippocampal neurogenesis
    • Palmer TD , Willhoite AR, Gage FH . 2000. Vascular niche for adult hippocampal neurogenesis . J Comp Neurol 425: 479-494.
    • (2000) J Comp Neurol , vol.425 , pp. 479-494
    • Palmer, T.D.1    Willhoite, A.R.2    Gage, F.H.3
  • 50
    • 84865477014 scopus 로고    scopus 로고
    • Effect of acute and fractionated irradiation on hippocampal neurogenesis
    • Park MK , Kim S , Jung U , Kim I, Kim JK , Roh C . 2012. Eff ect of acute and fractionated irradiation on hippocampal neurogenesis . Molecules 17 : 9462-9468 .
    • (2012) Molecules , vol.17 , pp. 9462-9468
    • Park, M.K.1    Kim, S.2    Jung, U.3    Kim, I.4    Kim, J.K.5    Roh, C.6
  • 51
    • 0242392011 scopus 로고    scopus 로고
    • The management of brain metastases
    • Patchell RA . 2003 . The management of brain metastases . Cancer Treat Rev 29: 533-540.
    • (2003) Cancer Treat Rev , vol.29 , pp. 533-540
    • Patchell, R.A.1
  • 52
    • 0035783914 scopus 로고    scopus 로고
    • Microglial signalling cascades in neurodegenerative disease
    • Pocock JM , Liddle AC . 2001 . Microglial signalling cascades in neurodegenerative disease . Prog Brain Res 132: 555-565.
    • (2001) Prog Brain Res , vol.132 , pp. 555-565
    • Pocock, J.M.1    Liddle, A.C.2
  • 54
    • 70349560028 scopus 로고    scopus 로고
    • The PPARalpha agonist fenofi brate preserves hippocampal neurogenesis and inhibits microglial activation after whole-brain irradiation
    • Ramanan S , Kooshki M , Zhao W , Hsu FC , Riddle DR , Robbins ME . 2009 . The PPARalpha agonist fenofi brate preserves hippocampal neurogenesis and inhibits microglial activation after whole-brain irradiation. Int J Radiat Oncol Biol Phys 75: 870-877.
    • (2009) Int J Radiat Oncol Biol Phys , vol.75 , pp. 870-877
    • Ramanan, S.1    Kooshki, M.2    Zhao, W.3    Hsu, F.C.4    Riddle, D.R.5    Robbins, M.E.6
  • 55
    • 2942552909 scopus 로고    scopus 로고
    • Chronic oxidative stress and radiation-induced late normal tissue injury: A review
    • Robbins MEC , Zhao W . 2004. Chronic oxidative stress and radiation-induced late normal tissue injury: A review . Int J Radiat Biol 80 : 251-259 .
    • (2004) Int J Radiat Biol , vol.80 , pp. 251-259
    • Mec, R.1    Zhao, W.2
  • 56
    • 3042799716 scopus 로고    scopus 로고
    • Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive defi cits in young mice
    • Rola R, Raber J , Rizk A , Otsuka S , VandenBerg SR, Morhardt DR, Fike JR . 2004. Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive defi cits in young mice . Exp Neurol 188 : 316-330 .
    • (2004) Exp Neurol , vol.188 , pp. 316-330
    • Rola, R.1    Raber, J.2    Rizk, A.3    Otsuka, S.4    Vandenberg, S.R.5    Morhardt, D.R.6    Fike, J.R.7
  • 57
    • 25444483568 scopus 로고    scopus 로고
    • High-LET radiation induces infl ammation and persistent changes in markers of hippocampal neurogenesis
    • Rola R , Sarkissian V , Obenaus A , Nelson GA , Otsuka S , Limoli CL , Fike JR . 2005 . High-LET radiation induces infl ammation and persistent changes in markers of hippocampal neurogenesis . Radiat Res 164(4 Pt 2) : 556-560 .
    • (2005) Radiat Res , vol.164 , Issue.4 , pp. 556-560
    • Rola, R.1    Sarkissian, V.2    Obenaus, A.3    Nelson, G.A.4    Otsuka, S.5    Limoli, C.L.6    Fike, J.R.7
  • 58
    • 0028914873 scopus 로고
    • Neuropsychological Effects of cranial radiation: Current knowledge and future directions
    • Roman DD , Sperduto PW . 1995. Neuropsychological Effects of cranial radiation: Current knowledge and future directions . Int J Radiat Oncol Biol Phys 31: 983-998.
    • (1995) Int J Radiat Oncol Biol Phys , vol.31 , pp. 983-998
    • Roman, D.D.1    Sperduto, P.W.2
  • 61
    • 84876003107 scopus 로고    scopus 로고
    • The PPAR ã agonist GW0742 inhibits neuroinfl ammation, but does not restore neurogenesis or prevent early delayed hippocampal-dependent cognitive impairment after whole-brain irradiation
    • Schnegg CI , Greene-Schloesser D , Kooshki M , Payne VS , Hsu FC , Robbins ME . 2013 . The PPAR ã agonist GW0742 inhibits neuroinfl ammation, but does not restore neurogenesis or prevent early delayed hippocampal-dependent cognitive impairment after whole-brain irradiation. Free Rad Biol Med 61: 1-9.
    • (2013) Free Rad Biol Med , vol.61 , pp. 1-9
    • Schnegg, C.I.1    Greene-Schloesser, D.2    Kooshki, M.3    Payne, V.S.4    Hsu, F.C.5    Robbins, M.E.6
  • 62
    • 33644846527 scopus 로고    scopus 로고
    • The management of radiation-induced brain injury
    • Shaw EG , Robbins ME . 2006 . The management of radiation-induced brain injury. Cancer Treat Res 128: 7-22.
    • (2006) Cancer Treat Res , vol.128 , pp. 7-22
    • Shaw, E.G.1    Robbins, M.E.2
  • 63
    • 0030738416 scopus 로고    scopus 로고
    • Apoptosis in the subependyma of young adult rats after single and fractionated doses of X-rays
    • Shinohara C , Gobbel GT , Lamborn KR , Tada E , Fike JR . 1997 . Apoptosis in the subependyma of young adult rats after single and fractionated doses of X-rays . Cancer Res 57: 2694-2702.
    • (1997) Cancer Res , vol.57 , pp. 2694-2702
    • Shinohara, C.1    Gobbel, G.T.2    Lamborn, K.R.3    Tada, E.4    Fike, J.R.5
  • 64
    • 28844501664 scopus 로고    scopus 로고
    • Estimators of the precision of stereological estimates: An example based on the CA1 pyramidal cell layer of rats
    • Slomianka L , West MJ . 2005. Estimators of the precision of stereological estimates: An example based on the CA1 pyramidal cell layer of rats . Neuroscience 136 : 757-767 .
    • (2005) Neuroscience , vol.136 , pp. 757-767
    • Slomianka, L.1    West, M.J.2
  • 65
    • 33750411459 scopus 로고    scopus 로고
    • Gamma-irradiation-induced intercellular adhesion molecule-1 (ICAM-1) expression is associated with catalase: Activation of Ap-1 and JNK
    • Son EW , Rhee DK , Pyo S . 2006 . Gamma-irradiation-induced intercellular adhesion molecule-1 (ICAM-1) expression is associated with catalase: Activation of Ap-1 and JNK . J Toxicol Environ Health A 69 : 2137-2155 .
    • (2006) J Toxicol Environ Health A , vol.69 , pp. 2137-2155
    • Son, E.W.1    Rhee, D.K.2    Pyo, S.3
  • 67
    • 0031010333 scopus 로고    scopus 로고
    • Reactive oxygen-mediated protein oxidation in aging and disease
    • Stadtman ER , Berlett BS . 1997 . Reactive oxygen-mediated protein oxidation in aging and disease . Chem Res Toxicol 10: 485-494.
    • (1997) Chem Res Toxicol , vol.10 , pp. 485-494
    • Stadtman, E.R.1    Berlett, B.S.2
  • 68
    • 0032937860 scopus 로고    scopus 로고
    • The role of microglia and macrophages in the pathophysiology of the CNS
    • Stoll G , Jander S . 1999 . The role of microglia and macrophages in the pathophysiology of the CNS . Prog Neurobiol 58 : 233-247 .
    • (1999) Prog Neurobiol , vol.58 , pp. 233-247
    • Stoll, G.1    Jander, S.2
  • 69
    • 0034718139 scopus 로고    scopus 로고
    • X-irradiation causes a prolonged reduction in cell proliferation in the dentate gyrus of adult rats
    • Tada E , Parent JM , Lowenstein DH , Fike JR . 2000 . X-irradiation causes a prolonged reduction in cell proliferation in the dentate gyrus of adult rats . Neuroscience 99 : 33-41 .
    • (2000) Neuroscience , vol.99 , pp. 33-41
    • Tada, E.1    Parent, J.M.2    Lowenstein, D.H.3    Fike, J.R.4
  • 70
    • 0023237237 scopus 로고
    • Neurotoxicity of prophylactic cranial irradiation in patients with small cell carcinoma of the lung
    • Twijnstra A , Boon PJ , Lormans AC , ten Velde GP . 1987 . Neurotoxicity of prophylactic cranial irradiation in patients with small cell carcinoma of the lung . Eur J Cancer Clin Oncol 23 : 983-986 .
    • (1987) Eur J Cancer Clin Oncol , vol.23 , pp. 983-986
    • Twijnstra, A.1    Boon, P.J.2    Lormans, A.C.3    Ten Velde, G.P.4
  • 71
    • 0036858432 scopus 로고    scopus 로고
    • Time course of proliferation and elimination of microglia/macrophages in diff erent neurodegenerative conditions
    • Vela JM , Y á ñ ez A , Gonz á lez B , Castellano B . 2002 . Time course of proliferation and elimination of microglia/macrophages in diff erent neurodegenerative conditions . J Neurotrauma 19 : 1503-1520 .
    • (2002) J Neurotrauma , vol.19 , pp. 1503-1520
    • Vela, J.M.1    Yáñez, A.2    González, B.3    Castellano, B.4
  • 72
    • 84875870356 scopus 로고    scopus 로고
    • Microglia: Actively surveying and shaping neuronal circuit structure and function
    • Wake H, Moorhouse AJ , Miyamoto A , Nabekura J . 2013. Microglia: Actively surveying and shaping neuronal circuit structure and function . Trends Neurosci 36 : 209-217 .
    • (2013) Trends Neurosci , vol.36 , pp. 209-217
    • Wake, H.1    Moorhouse, A.J.2    Miyamoto, A.3    Nabekura, J.4
  • 73
    • 0026339976 scopus 로고
    • Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator
    • West MJ , Slomianka LHJG , Gundersen HJ . 1991. Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator . Anatomic Rec 231 : 482-497 .
    • (1991) Anatomic Rec , vol.231 , pp. 482-497
    • West, M.J.1    Lhjg, S.2    Gundersen, H.J.3
  • 74
    • 78549282823 scopus 로고    scopus 로고
    • Voluntary running prevents progressive memory decline and increases adult hippocampal neurogenesis and growth factor expression after whole-brain irradiation
    • Wong-Goodrich SJE , Pfau ML , Flores CT , Fraser JA , Williams CL , Jones LW . 2010. Voluntary running prevents progressive memory decline and increases adult hippocampal neurogenesis and growth factor expression after whole-brain irradiation . Cancer Res 70 : 9329-9338 .
    • (2010) Cancer Res , vol.70 , pp. 9329-9338
    • Sje, W.1    Pfau, M.L.2    Flores, C.T.3    Fraser, J.A.4    Williams, C.L.5    Jones, L.W.6
  • 75
    • 0037453281 scopus 로고    scopus 로고
    • Radiation-induced permeability and leukocyte adhesion in the rat blood-brain barrier: Modulation with anti-ICAM-1 antibodies
    • Yuan H, Gaber MW, McColgan T , Naimark MD , Kiani MF , Merchant TE . 2003 . Radiation-induced permeability and leukocyte adhesion in the rat blood-brain barrier: Modulation with anti-ICAM-1 antibodies . Brain Res 969: 59-69.
    • (2003) Brain Res , vol.969 , pp. 59-69
    • Yuan, H.1    Gaber, M.W.2    McColgan, T.3    Naimark, M.D.4    Kiani, M.F.5    Merchant, T.E.6
  • 76
    • 34948897918 scopus 로고    scopus 로고
    • Oxidative damage pathways in relation to normal tissue injury
    • Zhao W, Diz DI, Robbins ME . 2007. Oxidative damage pathways in relation to normal tissue injury. Br J Radiol 80(1): S23-31.
    • (2007) Br J Radiol , vol.80 , Issue.1 , pp. S23-31
    • Zhao, W.1    Diz, D.I.2    Robbins, M.E.3
  • 77
    • 62349118232 scopus 로고    scopus 로고
    • Infl ammation and chronic oxidative stress in radiation-induced late normal tissue injury: Th erapeutic implications
    • Zhao W , Robbins ME . 2009 . Infl ammation and chronic oxidative stress in radiation-induced late normal tissue injury: Th erapeutic implications . Curr Med Chem 16: 130-143.
    • (2009) Curr Med Chem , vol.16 , pp. 130-143
    • Zhao, W.1    Robbins, M.E.2
  • 78
    • 0034743275 scopus 로고    scopus 로고
    • Effects of NF-kappaB1 (p50) targeted gene disruption on ionizing radiation-induced NF-kappaB activation and TNFalpha, IL-1alpha, IL-1beta and IL-6 mRNA expression in vivo
    • Zhou D , Yu T , Chen G , Brown SA , Yu Z , Mattson MP , Th ompson JS . 2001 . Effects of NF-kappaB1 (p50) targeted gene disruption on ionizing radiation-induced NF-kappaB activation and TNFalpha, IL-1alpha, IL-1beta and IL-6 mRNA expression in vivo . Int J Radiat Biol 77 : 763-772 .
    • (2001) Int J Radiat Biol , vol.77 , pp. 763-772
    • Zhou, D.1    Yu, T.2    Chen, G.3    Brown, S.A.4    Yu, Z.5    Mattson, M.P.6    Thompson, J.S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.