Recent developments in sample-pretreatment techniques for mass spectrometry-based metabolomics

TrAC - Trends in Analytical Chemistry

Volumn 61, Issue , 2014, Pages 157-167

  Raterink, Robert Jan ^a   Lindenburg, Peter W ^a   Vreeken, Rob J ^a   Ramautar, Rawi ^a   Hankemeier, Thomas ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Automation; Electromigration based extraction; High throughput analysis; Liquid liquid extraction; Mass spectrometry; Metabolomics; Protein removal; Sample pretreatment; Sample pretreatment protocol; Solid phase extraction

Indexed keywords

AUTOMATION; ELECTROMIGRATION; LIQUIDS; MASS SPECTROMETRY; PHASE SEPARATION; SOLVENT EXTRACTION; THROUGHPUT;

HIGH-THROUGHPUT ANALYSIS; LIQUID-LIQUID EXTRACTION; METABOLOMICS; PRE-TREATMENT; PROTEIN REMOVAL; SAMPLE PRETREATMENT; SOLID-PHASE EXTRACTION;

EFFLUENT TREATMENT;

CARBON NANOTUBE;

ANALYTIC METHOD; AUTOMATION; BIOCHEMISTRY; CAPILLARY ELECTROPHORESIS; CENTRIFUGATION; DRIED BLOOD SPOT TESTING; HIGH THROUGHPUT SCREENING; HYDROPHOBICITY; LIQUID LIQUID EXTRACTION; LIQUID PHASE MICROEXTRACTION; MASS SPECTROMETRY; METABOLOMICS; METHODOLOGY; MOLECULAR WEIGHT; NONHUMAN; PHENOTYPE; PROCESS DEVELOPMENT; PROTEIN ANALYSIS; REVIEW; SOLID PHASE EXTRACTION; TURBULENT FLOW CHROMATOGRAPHY; ULTRAFILTRATION; VALIDATION PROCESS; WORKFLOW;

EID: 84907008480     PISSN: 01659936     EISSN: 18793142     Source Type: Journal    
DOI: 10.1016/j.trac.2014.06.003     Document Type: Review

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