Sustained activation of interferon regulatory factor 3 during infection by paramyxoviruses requires MDA5

Journal of Innate Immunity

Volumn 6, Issue 5, 2014, Pages 650-662

  Grandvaux, Nathalie ^a,b   Guan, Xiaochun ^a,b   Yoboua, Fabrice ^a,b   Zucchini, Nicolas ^a,b   Fink, Karin ^a,b   Doyon, Priscilla ^c   Martin, Lydie ^a   Servant, Marc J ^c   Chartier, Stéfany ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b Medical Faculty   (Canada)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Host defense; Innate immunity; Interferon regulatory factor 3; Melanoma differentiation associated gene 5; Pathogen recognition receptors; Respiratory syncytial virus; Retinoic acid inducible gene I

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; DIMER; DIMETHYL SULFOXIDE; INTERFERON REGULATORY FACTOR 3; RETINOIC ACID INDUCIBLE PROTEIN I; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; IFIH1 PROTEIN, HUMAN; IRF3 PROTEIN, HUMAN; SMALL INTERFERING RNA; CYTOKINE; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5 PROTEIN; UNCLASSIFIED DRUG;

A549 CELL LINE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIMERIZATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOBLOTTING; IMMUNOPRECIPITATION; LUCIFERASE ASSAY; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5; NATIVE POLYACRYLAMIDE GEL ELECTROPHORESIS; PARAMYXOVIRUS INFECTION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; RNA INTERFERENCE; UBIQUITINATION; VIRUS TITRATION; CELL LINE; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; HUMAN RESPIRATORY SYNCYTIAL VIRUS; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; PHOSPHORYLATION; RESPIRATORY SYNCYTIAL VIRUS INFECTION; SIGNAL TRANSDUCTION; VIROLOGY; PROTEIN EXPRESSION;

CELL LINE; DEAD-BOX RNA HELICASES; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; IMMUNITY, INNATE; INTERFERON REGULATORY FACTOR-3; PHOSPHORYLATION; PROTEOLYSIS; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UBIQUITINATION;

EID: 84906937301     PISSN: 1662811X     EISSN: 16628128     Source Type: Journal    
DOI: 10.1159/000360764     Document Type: Article

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