Olive leaf extracts protect cardiomyocytes against 4-hydroxynonenal-induced toxicity in vitro: Comparison with oleuropein, hydroxytyrosol, and quercetin

Planta Medica

Volumn 80, Issue 12, 2014, Pages 984-992

  Bali, Elif Burcu ^a   Ergin, Volkan ^a   Rackova, Lucia ^b   Bayraktar, Oǧuz ^c   Küçükboyaci, Nurgün ^a   Karasu, Çimen ^a  

^a GAZI UNIVERSITY   (Turkey)

^b INSTITUTE OF EXPERIMENTAL PHARMACOLOGY AND TOXICOLOGY   (Slovakia)

^c IZMIR INSTITUTE OF TECHNOLOGY   (Turkey)

Author keywords

4 hydroxynonenal; cardiomyocytes; hydroxytyrosol; Olea europaea L.; Oleaceae; oleuropein; olive leaf extract; quercetin

Indexed keywords

4 HYDROXYNONENAL; ACTEOSIDE; CARDIOVASCULAR AGENT; CASPASE 3; HEAT SHOCK PROTEIN 27; HYDROXYTYROSOL; JANUS KINASE; LUTEOLIN; OLEUROPEIN; OLIVE TREE EXTRACT; PLANT EXTRACT; PROTEIN C JUN; QUERCETIN; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; 3,4-DIHYDROXYPHENYLETHANOL; 4-HYDROXY-2-NONENAL; ALDEHYDE; ANTIOXIDANT; IRIDOID; PHENETHYL ALCOHOL; POLYPHENOL; PROTECTIVE AGENT; PROTEIN SERINE THREONINE KINASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; HEART MUSCLE CELL; HEART PROTECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OLIVE TREE; OXIDATIVE STRESS; PROTEIN PHOSPHORYLATION; RAT; UPREGULATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; CELL SURVIVAL; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECTS; METABOLISM; MITOCHONDRION; PLANT LEAF;

OLEA EUROPAEA; OLEACEAE; RATTUS;

ALDEHYDES; ANIMALS; ANTIOXIDANTS; CASPASE 3; CELL SURVIVAL; IN VITRO TECHNIQUES; IRIDOIDS; MITOCHONDRIA; MYOCYTES, CARDIAC; OLEA; OXIDATIVE STRESS; PHENYLETHYL ALCOHOL; PLANT EXTRACTS; PLANT LEAVES; POLYPHENOLS; PROTECTIVE AGENTS; PROTEIN-SERINE-THREONINE KINASES; QUERCETIN; RATS; TRANSCRIPTION FACTORS;

EID: 84906936735     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0034-1382881     Document Type: Article

References (40)

1. Poli G., Schaur R. J., Siems W. G., Leonarduzzi G. 4-hydroxynonenal: a membrane lipid oxidation product of medicinal interest. Med Res Rev: 2008; 28 569 631 (Pubitemid 351842143)
2. Uchida K., Stadtman E. R. Modification of histidine residues in proteins by reaction with 4-hydroxynonenal. Proc Natl Acad Sci U S A: 1992; 89 4544 4548
3. Szapacs M. E., Riggins J. N., Zimmerman L. J., Liebler D. C. Covalent adduction of human serum albumin by 4-hydroxy-2-nonenal: kinetic analysis of competing alkylation reactions. Biochemistry: 2006; 45 10521 10528 (Pubitemid 44320468)
4. Grune T., Davies K. J. The proteasomal system and HNE-modified proteins. Mol Aspects Med: 2003; 24 195 204 (Pubitemid 36945019)
5. Galvani S., Coatrieux C., Elbaz M., Grazide M. H., Thiers J. C., Parini A., Uchida K., Kamar N., Rostaing L., Baltas M., Salvayre R., Nègre-Salvayre A. Carbonyl scavenger and antiatherogenic effects of hydrazine derivatives. Free Radic Biol Med: 2008; 45 1457 1467
6. Miller D. M., Singh I. N., Wang J. A., Hall E. D. Administration of the Nrf2-ARE activators sulforaphane and carnosic acid attenuates 4-hydroxy-2-nonenal-induced mitochondrial dysfunction ex vivo. Free Radic Biol Med: 2013; 57 1 9
7. Karasu C. Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment. Open Cardiovasc Med J: 2010; 4 240 256
8. Sakul A., Cumaoǧlu A., Aydin E., Ari N., Dilsiz N., Karasu C. Age- and diabetes-induced regulation of oxidative protein modification in rat brain and peripheral tissues: consequences of treatment with antioxidant pyridoindole. Exp Gerontol: 2013; 48 476 484
9. Qin F., Simeone M., Patel R. Inhibition of NADPH oxidase reduces myocardial oxidative stress and apoptosis and improves cardiac function in heart failure after myocardial infarction. Free Radic Biol Med: 2007; 43 271 281 (Pubitemid 46977168)
10. Anderson E. J., Katunga L. A., Willis M. S. Mitochondria as a source and target of lipid peroxidation products in healthy and diseased heart. Clin Exp Pharmacol Physiol: 2012; 39 179 193
11. He L., Liu B., Dai Z., Zhang H. F., Zhang Y. S., Luo X. J., Ma Q. L., Peng J. Alpha lipoic acid protects heart against myocardial ischemia-reperfusion injury through a mechanism involving aldehyde dehydrogenase 2 activation. Eur J Pharmacol: 2012; 678 32 38
12. Bayçin D., Altiok E., Ulkü S., Bayraktar O. Adsorption of olive leaf (Olea europaea L.) antioxidants on silk fibroin. J Agric Food Chem: 2007; 55 1227 1236
13. Altok E., Baycin D., Bayraktar O., Semra Ulkü S. Isolation of polyphenols from the extracts of olive leaves (Olea europaea L.) by adsorption on silk fibroin. Sep Purif Technol: 2008; 62 342 348
14. Dekanski D., Janicijevic-Hudomal S., Tadic V., Markovic G., Arsic I., Mitrovic D. M. Phytochemical analysis and gastroprotective activity of an olive leaf extract. J Serb Chem Soc: 2009; 74 367 377
15. Mylonaki S., Kiassos E., Makris D. P., Kefalas P. Optimisation of the extraction of olive (Olea europaea) leaf phenolics using water/ethanol-based solvent systems and response surface methodology. Anal Bioanal Chem: 2008; 392 977 985
16. Koca U., Süntar I., Akkol E. K., Yilmazer D., Alper M. Wound repair potential of Olea europaea L. leaf extracts revealed by in vivo experimental models and comparative evaluation of the extracts antioxidant activity. J Med Food: 2011; 14 140 146
17. Poudyal H., Campbell F., Brown L. Olive leaf extract attenuates cardiac, hepatic, and metabolic changes in high carbohydrate-, high fat-fed rats. J Nutr: 2010; 140 946 953
18. Manna C., Migliardi V., Golino P., Scognamiglio A., Galletti P., Chiariello M., Zappia V. Oleuropein prevents oxidative myocardial injury induced by ischemia and reperfusion. J Nutr Biochem: 2004; 15 461 466 (Pubitemid 39118492)
19. 2 toxicity in insulin secreting β -cells. Acta Biochim Pol: 2011; 58 45 50
20. Cumaoǧlu A., Ari N., Kartal M., Karasu C. Polyphenolic extracts from Olea europaea L. protect against cytokine-induced β -cell damage through maintenance of redox homeostasis. Rejuvenation Res: 2011; 14 325 334
21. Stefek M., Karasu C. Eye lens in aging and diabetes: effect of quercetin. Rejuvenation Res: 2011; 14 525 534
22. Hur S. J., Lee S. J., Kim D. H., Chun S. C., Lee S. K. Onion extract structural changes during in vitro digestion and its potential antioxidant effect on brain lipids obtained from low- and high-fat-fed mice. Free Radic Res: 2013; 47 1009 1015
23. Budas G. R., Disatnik M. H., Chen C. H., Mochly-Rosen D. Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCvarepsilon) knockout mice. J Mol Cell Cardiol: 2010; 48 757 764
24. Ergin V., Hariry R. E., Karasu C. Carbonyl stress in aging process: role of vitamins and phytochemicals as redox regulators. Aging Dis: 2013; 4 276 294
25. Liao J., Sun A., Xie Y., Isse T., Kawamoto T., Zou Y., Ge J. Aldehyde dehydrogenase-2 deficiency aggravates cardiac dysfunction elicited by endoplasmic reticulum stress induction. Mol Med: 2012; 18 785 793
26. Wei J., Wang W., Chopra I., Li H. F., Dougherty C. J., Adi J., Adi N., Wang H., Webster K. A. c-Jun N-terminal kinase (JNK-1) confers protection against brief but not extended ischemia during acute myocardial infarction. J Biol Chem: 2011; 286 13995 14006
27. Rouse J., Cohen P., Trigon S., Morange M., Alonso-Llamazares A., Zamanillo D., Hunt T., Nebreda A. R. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell: 1994; 78 1027 1037 (Pubitemid 24292330)
28. Mehlen P., Arrigo A. P. The serum-induced phosphorylation of mammalian hsp27 correlates with changes in its intracellular localization and levels of oligomerization. Eur J Biochem: 1994; 221 327 334 (Pubitemid 24120577)
29. Monastyrskaya E. A., Andreeva L. V., Duchen M. R., Wiegant F., Bayda L. A., Manukhina E. B., Malyshev I. Y. Adaptation to heat of cardiomyoblasts in culture protects them against heat shock: role of nitric oxide and heat shock proteins. Biochemistry (Mosc): 2003; 68 816 821
30. Kutuk O., Poli G., Basaga H. Resveratrol protects against 4-hydroxynonenal-induced apoptosis by blocking JNK and c-JUN/AP-1 signaling. Toxicol Sci: 2006; 90 120 132 (Pubitemid 43264732)
31. Jang Y. J., Kim J., Shim J., Kim J., Byun S., Oak M. H., Lee K. W., Lee H. J. Kaempferol attenuates 4-hydroxynonenal-induced apoptosis in PC12 cells by directly inhibiting NADPH oxidase. J Pharmacol Exp Ther: 2011; 337 747 754
32. Jin H. B., Yang Y. B., Song Y. L., Zhang Y. C., Li Y. R. Protective roles of quercetin in acute myocardial ischemia and reperfusion injury in rats. Mol Biol Rep: 2012; 39 11005 11009
33. Yan L., Zhang J. D., Wang B., Lv Y. J., Jiang H., Liu G. L., Qiao Y., Ren M., Guo X. F. Quercetin inhibits left ventricular hypertrophy in spontaneously hypertensive rats and inhibits angiotensin II-induced H9c2 cells hypertrophy by enhancing PPAR- γ expression and suppressing AP-1 activity. PLoS One: 2013; 8 e72548
34. Khreiss T., József L., Hossain S., Chan J. S., Potempa L. A., Filep J. G. Loss of pentameric symmetry of C-reactive protein is associated with delayed apoptosis of human neutrophils. J Biol Chem: 2002; 277 40775 40781 (Pubitemid 35215662)
35. Li F., Wu J. H., Wang Q. H., Shu Y. L., Wan C. W., Chan C. O., Kam-Wah Mok D., Chan S. W. Gui-ling-gao, a traditional Chinese functional food, prevents oxidative stress-induced apoptosis in H9c2 cardiomyocytes. Food Funct: 2013; 4 745 753
36. Angeloni C., Spencer J. P., Leoncini E., Biagi P. L., Hrelia S. Role of quercetin and its in vivo metabolites in protecting H9c2 cells against oxidative stress. Biochimie: 2007; 89 73 82 (Pubitemid 44959282)
37. de Bock M., Derraik J. G., Brennan C. M., Biggs J. B., Morgan P. E., Hodgkinson S. C., Hofman P. L., Cutfield W. S. Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: a randomized, placebo-controlled, crossover trial. PLoS One: 2013; 8 e57622
38. Janjic D., Wollheim C. B. Islet cell metabolism is reflected by the MTT (tetrazolium) colorimetric assay. Diabetologia: 1992; 35 482 485
39. 2 in cultured endothelial cells. Arch Biochem Biophys: 1993; 302 348 355 (Pubitemid 23212681)
40. Salvioli S., Ardizzoni A., Franceschi C., Cossarizza A. JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. FEBS Lett: 1997; 411 77 82 (Pubitemid 27298375)