Mechanistic target of rapamycin complex 1 (mTORC1)-mediated phosphorylation is governed by competition between substrates for interaction with raptor

Journal of Biological Chemistry

Volumn 288, Issue 1, 2013, Pages 10-19

  Dennis, Michael D ^a   Kimball, Scot R ^a   Jefferson, Leonard S ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEX 1; CULTURE SYSTEMS; DOWNSTREAM TARGET; GENES ENCODING; IMMUNOPRECIPITATES; IMMUNOPRECIPITATIONS; MOUSE EMBRYONIC FIBROBLASTS; MOUSE LIVER; TARGET OF RAPAMYCIN;

CELL CULTURE; MAMMALS;

PHOSPHORYLATION;

INITIATION FACTOR 4E BINDING PROTEIN 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; REGULATORY ASSOCIATED PROTEIN OF MAMMALIAN TARGET OF RAPAMYCIN COMPLEX; S6 KINASE; SCAFFOLD PROTEIN; THREONINE; UNCLASSIFIED DRUG;

4E BP1 GENE; 4E BP2 GENE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVATION; FIBROBLAST; IMMUNOPRECIPITATION; LIVER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

ANIMALS; CARRIER PROTEINS; EUKARYOTIC INITIATION FACTORS; FIBROBLASTS; GENE EXPRESSION REGULATION; IMMUNOPRECIPITATION; LIVER; MALE; MICE; MICE, KNOCKOUT; MUTATION; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN BIOSYNTHESIS; PROTEINS; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; TRANSFECTION;

MUS; RAPTORES;

EID: 84872054005     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.402461     Document Type: Article

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