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Volumn 171, Issue 18, 2014, Pages 4273-4288

Buprenorphine signalling is compromised at the N40D polymorphism of the human μ opioid receptor in vitro

Author keywords

[No Author keywords available]

Indexed keywords

BUPRENORPHINE; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MU OPIATE RECEPTOR; NARCOTIC ANALGESIC AGENT;

EID: 84906825514     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12785     Document Type: Article
Times cited : (24)

References (57)
  • 1
    • 84872527828 scopus 로고    scopus 로고
    • Conformational ensemble view of G protein-coupled receptors and the effect of mutations and ligand binding
    • Abrol R, Kim SK, Bray JK, Trzaskowski B, Goddard WA 3rd, (2013). Conformational ensemble view of G protein-coupled receptors and the effect of mutations and ligand binding. Methods Enzymol 520: 31-48.
    • (2013) Methods Enzymol , vol.520 , pp. 31-48
    • Abrol, R.1    Kim, S.K.2    Bray, J.K.3    Trzaskowski, B.4    Goddard III, W.A.5
  • 3
    • 0033567335 scopus 로고    scopus 로고
    • Differential G-protein activation by alkaloid and peptide opioid agonists in the human neuroblastoma cell line SK-N-BE
    • Allouche S, Polastron J, Hasbi A, Homburger V, Jauzac P, (1999). Differential G-protein activation by alkaloid and peptide opioid agonists in the human neuroblastoma cell line SK-N-BE. Biochem J 342: 71-78.
    • (1999) Biochem J , vol.342 , pp. 71-78
    • Allouche, S.1    Polastron, J.2    Hasbi, A.3    Homburger, V.4    Jauzac, P.5
  • 4
    • 78650926798 scopus 로고    scopus 로고
    • Expression G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis
    • Atwood BK, Lopez J, Wager-Miller J, Mackie K, Straiker A, (2011). Expression G protein-coupled receptors and related proteins in HEK293, AtT20, BV2, and N18 cell lines as revealed by microarray analysis. BMC Genomics 12: 14.
    • (2011) BMC Genomics , vol.12 , pp. 14
    • Atwood, B.K.1    Lopez, J.2    Wager-Miller, J.3    MacKie, K.4    Straiker, A.5
  • 5
    • 0035793631 scopus 로고    scopus 로고
    • A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling
    • Befort K, Filliol D, Decaillot FM, Gaveriaux-Ruff C, Hoehe MR, Kieffer BL, (2001). A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling. J Biol Chem 276: 3130-3137.
    • (2001) J Biol Chem , vol.276 , pp. 3130-3137
    • Befort, K.1    Filliol, D.2    Decaillot, F.M.3    Gaveriaux-Ruff, C.4    Hoehe, M.R.5    Kieffer, B.L.6
  • 7
    • 2042527666 scopus 로고    scopus 로고
    • Effect of the A118G polymorphism on binding affinity, potency and agonist-mediated endocytosis, desensitization and resensitization of the human mu-opioid receptor
    • Beyer A, Koch T, Schroder H, Schulz S, Hollt V, (2004). Effect of the A118G polymorphism on binding affinity, potency and agonist-mediated endocytosis, desensitization and resensitization of the human mu-opioid receptor. J Neurochem 89: 553-560.
    • (2004) J Neurochem , vol.89 , pp. 553-560
    • Beyer, A.1    Koch, T.2    Schroder, H.3    Schulz, S.4    Hollt, V.5
  • 8
    • 13144261678 scopus 로고    scopus 로고
    • Single-nucleotide polymorphism in the human mu opioid receptor gene alters β-endorphin binding and activity: Possible implications for opiate addiction
    • Bond C, LaForge KS, Tian M, Melia D, Zhang S, Borg L, et al. (1998). Single-nucleotide polymorphism in the human mu opioid receptor gene alters β-endorphin binding and activity: possible implications for opiate addiction. Proc Natl Acad Sci USA 95: 9608-9613.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9608-9613
    • Bond, C.1    Laforge, K.S.2    Tian, M.3    Melia, D.4    Zhang, S.5    Borg, L.6
  • 11
    • 84875469202 scopus 로고    scopus 로고
    • Recent developments in the study of opioid receptors
    • Cox B, (2013). Recent developments in the study of opioid receptors. Mol Pharmacol 83: 723-728.
    • (2013) Mol Pharmacol , vol.83 , pp. 723-728
    • Cox, B.1
  • 13
    • 83355160649 scopus 로고    scopus 로고
    • Elucidation of mu-opioid gene structure: How genetics can help predict therapeutic response to opioids
    • Diatchenko L, Robinson JE, Maixner W, (2011). Elucidation of mu-opioid gene structure: how genetics can help predict therapeutic response to opioids. Eur J Pain Suppl 5: 433-448.
    • (2011) Eur J Pain Suppl , vol.5 , pp. 433-448
    • Diatchenko, L.1    Robinson, J.E.2    Maixner, W.3
  • 14
    • 45749146195 scopus 로고    scopus 로고
    • Conformational rearrangements and signalling cascades involved in ligand-biased mitogen-activated protein kinase signalling through the β1-adrenergic receptor
    • Galandrin S, Oligny-Longpre G, Bonin H, Ogawa K, Gales C, Bouvier M, (2008). Conformational rearrangements and signalling cascades involved in ligand-biased mitogen-activated protein kinase signalling through the β1-adrenergic receptor. Mol Pharmacol 74: 162-172.
    • (2008) Mol Pharmacol , vol.74 , pp. 162-172
    • Galandrin, S.1    Oligny-Longpre, G.2    Bonin, H.3    Ogawa, K.4    Gales, C.5    Bouvier, M.6
  • 15
  • 17
    • 44849121421 scopus 로고    scopus 로고
    • Post-activation-mediated changes in opioid receptors detected by N-terminal antibodies
    • Gupta A, Rozenfeld R, Gomes I, Raehal KM, Decaillot FM, Bohn LM, et al. (2008). Post-activation-mediated changes in opioid receptors detected by N-terminal antibodies. J Biol Chem 283: 10735-10744.
    • (2008) J Biol Chem , vol.283 , pp. 10735-10744
    • Gupta, A.1    Rozenfeld, R.2    Gomes, I.3    Raehal, K.M.4    Decaillot, F.M.5    Bohn, L.M.6
  • 18
    • 84884683292 scopus 로고    scopus 로고
    • Fluorescence correlation spectroscopy analysis of serotonin, adrenergic, muscarinic, and dopamine receptor dimerization: The oligomer number puzzle
    • Herrick-Davis K, Grinde E, Cowan A, Mazurkiewicz JE, (2013). Fluorescence correlation spectroscopy analysis of serotonin, adrenergic, muscarinic, and dopamine receptor dimerization: the oligomer number puzzle. Mol Pharmacol 84: 630-642.
    • (2013) Mol Pharmacol , vol.84 , pp. 630-642
    • Herrick-Davis, K.1    Grinde, E.2    Cowan, A.3    Mazurkiewicz, J.E.4
  • 19
    • 84055223534 scopus 로고    scopus 로고
    • A common single nucleotide polymorphism A118G of the μ opioid receptor alters its N-glycosylation and protein stability
    • Huang P, Chen C, Mague SD, Blendy JA, Liu-Chen LY, (2012). A common single nucleotide polymorphism A118G of the μ opioid receptor alters its N-glycosylation and protein stability. Biochem J 441: 379-386.
    • (2012) Biochem J , vol.441 , pp. 379-386
    • Huang, P.1    Chen, C.2    Mague, S.D.3    Blendy, J.A.4    Liu-Chen, L.Y.5
  • 20
    • 77952354490 scopus 로고    scopus 로고
    • Seven transmembrane receptors as shapeshifting proteins: The impact of allosteric modulation and functional selectivity on new drug discovery
    • Kenakin T, Miller LJ, (2010). Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery. Pharmacol Rev 62: 265-304.
    • (2010) Pharmacol Rev , vol.62 , pp. 265-304
    • Kenakin, T.1    Miller, L.J.2
  • 21
    • 8544257029 scopus 로고    scopus 로고
    • The 118 A > G polymorphism in the human μ-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease
    • Klepstad P, Rakvag TT, Kaasa S, Holthe M, Dale O, Borchgrevink PC, et al. (2004). The 118 A > G polymorphism in the human μ-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease. Acta Anaesthesiol Scand 48: 1232-1239.
    • (2004) Acta Anaesthesiol Scand , vol.48 , pp. 1232-1239
    • Klepstad, P.1    Rakvag, T.T.2    Kaasa, S.3    Holthe, M.4    Dale, O.5    Borchgrevink, P.C.6
  • 22
    • 79954583889 scopus 로고    scopus 로고
    • Influence from genetic variability on opioid use for cancer pain: A European genetic association study of 2294 cancer pain patients
    • Klepstad P, Fladvad T, Skorpen F, Bjordal K, Caraceni A, Dale O, et al. (2011). Influence from genetic variability on opioid use for cancer pain: a European genetic association study of 2294 cancer pain patients. Pain 152: 1139-1145.
    • (2011) Pain , vol.152 , pp. 1139-1145
    • Klepstad, P.1    Fladvad, T.2    Skorpen, F.3    Bjordal, K.4    Caraceni, A.5    Dale, O.6
  • 23
    • 84906824182 scopus 로고    scopus 로고
    • Cellular signalling of non-synonymous single nucleotide polymorphisms of the human μ-Opioid Receptor (OPRM1)
    • doi: 10.1111/bph.12644; In Press.
    • Knapman A, Connor M, (2014). Cellular signalling of non-synonymous single nucleotide polymorphisms of the human μ-Opioid Receptor (OPRM1). Br J Pharmacol doi: 10.1111/bph.12644; In Press.
    • (2014) Br J Pharmacol
    • Knapman, A.1    Connor, M.2
  • 25
    • 84892775419 scopus 로고    scopus 로고
    • A real-time, fluorescence-based assay for measuring μ-opioid receptor modulation of adenylyl cyclase activity in Chinese hamster ovary cells
    • Knapman A, Abogadie F, McIntyre P, Connor M, (2014). A real-time, fluorescence-based assay for measuring μ-opioid receptor modulation of adenylyl cyclase activity in Chinese hamster ovary cells. J Biomol Screen 19: 223-231.
    • (2014) J Biomol Screen , vol.19 , pp. 223-231
    • Knapman, A.1    Abogadie, F.2    McIntyre, P.3    Connor, M.4
  • 26
    • 34548653719 scopus 로고    scopus 로고
    • The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor
    • Kroslak T, LaForge KS, Gianotti RJ, Ho A, Nielsen DA, Kreek MJ, (2007). The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor. J Neurochem 103: 77-87.
    • (2007) J Neurochem , vol.103 , pp. 77-87
    • Kroslak, T.1    Laforge, K.S.2    Gianotti, R.J.3    Ho, A.4    Nielsen, D.A.5    Kreek, M.J.6
  • 27
    • 0034128416 scopus 로고    scopus 로고
    • Molecular mechanisms of opioid receptor signalling
    • Law PY, Yung HW, Loh HH, (2000). Molecular mechanisms of opioid receptor signalling. Annu Rev Pharmacol Toxicol 40: 389-430.
    • (2000) Annu Rev Pharmacol Toxicol , vol.40 , pp. 389-430
    • Law, P.Y.1    Yung, H.W.2    Loh, H.H.3
  • 29
    • 13244298667 scopus 로고    scopus 로고
    • Are μ-opioid receptor polymorphisms important for clinical opioid therapy?
    • Lotsch J, Geisslinger G, (2005). Are μ-opioid receptor polymorphisms important for clinical opioid therapy? Trends Mol Med 11: 82-89.
    • (2005) Trends Mol Med , vol.11 , pp. 82-89
    • Lotsch, J.1    Geisslinger, G.2
  • 30
    • 25844477611 scopus 로고    scopus 로고
    • Composition and function of G protein-coupled receptor signalsomes controlling mitogen-activated protein kinase activity
    • Luttrell LM, (2005). Composition and function of G protein-coupled receptor signalsomes controlling mitogen-activated protein kinase activity. J Mol Neurosci 26L: 253-264.
    • (2005) J Mol Neurosci , vol.26 L , pp. 253-264
    • Luttrell, L.M.1
  • 31
    • 77952420724 scopus 로고    scopus 로고
    • OPRM1 SNP (A118G): Involvement in disease development, treatment response, and animal models
    • Mague SD, Blendy JA, (2010). OPRM1 SNP (A118G): involvement in disease development, treatment response, and animal models. Drug Alcohol Depend 108: 172-182.
    • (2010) Drug Alcohol Depend , vol.108 , pp. 172-182
    • Mague, S.D.1    Blendy, J.A.2
  • 34
    • 84879054442 scopus 로고    scopus 로고
    • Detection of G protein-selective G protein-coupled receptor (GPCR) conformations in live cells
    • Malik RU, Ritt M, DeVree BT, Neubig RR, Sunahara RK, Sivaramakrishnan S, (2013). Detection of G protein-selective G protein-coupled receptor (GPCR) conformations in live cells. J Biol Chem 288: 17167-17178.
    • (2013) J Biol Chem , vol.288 , pp. 17167-17178
    • Malik, R.U.1    Ritt, M.2    Devree, B.T.3    Neubig, R.R.4    Sunahara, R.K.5    Sivaramakrishnan, S.6
  • 36
    • 33846926501 scopus 로고    scopus 로고
    • 2+ channels by heterologously expressed wild-type and mutant human μ opioid receptors (hMORs) containing the A118G single-nucleotide polymorphism
    • 2+ channels by heterologously expressed wild-type and mutant human μ opioid receptors (hMORs) containing the A118G single-nucleotide polymorphism. J Neurophysiol 97: 1058-1067.
    • (2007) J Neurophysiol , vol.97 , pp. 1058-1067
    • Margas, W.1    Zubkoff, I.2    Schuler, H.G.3    Janicki, P.K.4    Ruiz-Velasco, V.5
  • 37
    • 78049353594 scopus 로고    scopus 로고
    • IR3 potassium channels and NMDA receptor conductance by l- and d- methadone in rat locus coeruleus
    • IR3 potassium channels and NMDA receptor conductance by l- and d- methadone in rat locus coeruleus. Br J Pharmacol 161: 1403-1413.
    • (2010) Br J Pharmacol , vol.161 , pp. 1403-1413
    • Matsui, A.1    Williams, J.T.2
  • 38
    • 84877892328 scopus 로고    scopus 로고
    • Consequences of the 118A>G polymorphism in the OPRM1 gene: Translation from bench to bedside?
    • Mura E, Govoni S, Racchi M, Carossa V, Ranzani GN, Allegri M, et al. (2013). Consequences of the 118A>G polymorphism in the OPRM1 gene: translation from bench to bedside? J Pain Res 6: 331-353.
    • (2013) J Pain Res , vol.6 , pp. 331-353
    • Mura, E.1    Govoni, S.2    Racchi, M.3    Carossa, V.4    Ranzani, G.N.5    Allegri, M.6
  • 42
    • 33845311870 scopus 로고    scopus 로고
    • Ligand-specific receptor states: Implications for opiate receptor signaling and regulation
    • Pineyro G, Archer-Lahlou E, (2007). Ligand-specific receptor states: implications for opiate receptor signaling and regulation. Cell Signal 19: 8-19.
    • (2007) Cell Signal , vol.19 , pp. 8-19
    • Pineyro, G.1    Archer-Lahlou, E.2
  • 45
    • 34249794271 scopus 로고    scopus 로고
    • Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene
    • Reyes-Gibby CC, Shete S, Rakvag T, Bhat SV, Skorpen F, Bruera E, et al. (2007). Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene. Pain 130: 25-30.
    • (2007) Pain , vol.130 , pp. 25-30
    • Reyes-Gibby, C.C.1    Shete, S.2    Rakvag, T.3    Bhat, S.V.4    Skorpen, F.5    Bruera, E.6
  • 47
    • 0028148244 scopus 로고
    • Site-specific recombination: Developments and applications
    • Sauer B, (1994). Site-specific recombination: developments and applications. Curr Opin Biotechnol 5: 521-527.
    • (1994) Curr Opin Biotechnol , vol.5 , pp. 521-527
    • Sauer, B.1
  • 49
    • 46049118417 scopus 로고    scopus 로고
    • Variable response to opioid treatment: Any genetic predictors in sight?
    • Skorpen F, Laugsand EA, Klepdstad P, Kaasa S, (2008). Variable response to opioid treatment: any genetic predictors in sight? Palliat Med 22: 310-327.
    • (2008) Palliat Med , vol.22 , pp. 310-327
    • Skorpen, F.1    Laugsand, E.A.2    Klepdstad, P.3    Kaasa, S.4
  • 50
    • 84906937723 scopus 로고    scopus 로고
    • Assessment of opioid receptor μ1 gene A118G polymorphism and its association with pain intensity in patients with fibromyalgia
    • doi: 10.1007/200296-014-2995-1; In Press.
    • Solak O, Erdogan MO, Yildiz H, Ulasli AM, Yaman F, Terzi ES, et al. (2014). Assessment of opioid receptor μ1 gene A118G polymorphism and its association with pain intensity in patients with fibromyalgia. Rheumatol Int doi: 10.1007/200296-014-2995-1; In Press.
    • (2014) Rheumatol Int
    • Solak, O.1    Erdogan, M.O.2    Yildiz, H.3    Ulasli, A.M.4    Yaman, F.5    Terzi, E.S.6
  • 52
    • 84884565882 scopus 로고    scopus 로고
    • Effects of OPRM1 A118G polymorphism on epidural analgesia with fentanyl during labor: A meta-analysis
    • Song Z, Du B, Wang K, Shi X, (2013). Effects of OPRM1 A118G polymorphism on epidural analgesia with fentanyl during labor: a meta-analysis. Genet Test Mol Biomarkers 17: 743-749.
    • (2013) Genet Test Mol Biomarkers , vol.17 , pp. 743-749
    • Song, Z.1    Du, B.2    Wang, K.3    Shi, X.4
  • 53
    • 9644279627 scopus 로고    scopus 로고
    • Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans
    • Srinivasan S, Lubrano-Berthelier C, Govaerts C, Picard F, Santiago P, Conklin BR, et al. (2004). Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans. J Clin Invest 114: 1158-1164.
    • (2004) J Clin Invest , vol.114 , pp. 1158-1164
    • Srinivasan, S.1    Lubrano-Berthelier, C.2    Govaerts, C.3    Picard, F.4    Santiago, P.5    Conklin, B.R.6
  • 54
    • 66749153181 scopus 로고    scopus 로고
    • Buprenorphine is a weak partial agonist that inhibits opioid receptor desensitization
    • Virk MS, Arttamangkul S, Birdsong WT, Williams JT, (2009). Buprenorphine is a weak partial agonist that inhibits opioid receptor desensitization. J Neurosci 29: 7341-7348.
    • (2009) J Neurosci , vol.29 , pp. 7341-7348
    • Virk, M.S.1    Arttamangkul, S.2    Birdsong, W.T.3    Williams, J.T.4
  • 55
    • 84877156228 scopus 로고    scopus 로고
    • Association of OPRM1 and COMT single-nucleotide polymorphisms with hospital length of stay and treatment of neonatal abstinence syndrome
    • Wachman EM, Hayes MJ, Brown MS, Paul J, Harvey-Wilkes K, Terrin N, et al. (2013). Association of OPRM1 and COMT single-nucleotide polymorphisms with hospital length of stay and treatment of neonatal abstinence syndrome. JAMA 309: 1821-1827.
    • (2013) JAMA , vol.309 , pp. 1821-1827
    • Wachman, E.M.1    Hayes, M.J.2    Brown, M.S.3    Paul, J.4    Harvey-Wilkes, K.5    Terrin, N.6
  • 56
    • 70350620288 scopus 로고    scopus 로고
    • Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment
    • Walter C, Lotsch J, (2009). Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment. Pain 146: 270-275.
    • (2009) Pain , vol.146 , pp. 270-275
    • Walter, C.1    Lotsch, J.2
  • 57
    • 25444491710 scopus 로고    scopus 로고
    • Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G
    • Zhang Y, Wang D, Johnson AD, Papp AC, Sadee W, (2005). Allelic expression imbalance of human mu opioid receptor (OPRM1) caused by variant A118G. J Biol Chem 280: 32618-32624.
    • (2005) J Biol Chem , vol.280 , pp. 32618-32624
    • Zhang, Y.1    Wang, D.2    Johnson, A.D.3    Papp, A.C.4    Sadee, W.5


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