Assessment of opioid receptor μ1 gene A118G polymorphism and its association with pain intensity in patients with fibromyalgia

Rheumatology International

Volumn 34, Issue 9, 2014, Pages 1257-1261

  Solak, Özlem ^a   Erdoǧan, Müjgan Özdemir ^a   Yildiz, Handan ^a   Ulaşli, Alper Murat ^a   Yaman, Fatima ^a   Terzi, Evrim Suna Arikan ^a   Ulu, Sena ^a   Dündar, Ümit ^a   Solak, Mustafa ^a  

^a AFYON KOCATEPE UNIVERSITY   (Turkey)

Author keywords

Fibromyalgia; Genetics; OPRM1 polymorphism; Pain

Indexed keywords

MU 1 OPIATE RECEPTOR; MU OPIATE RECEPTOR; UNCLASSIFIED DRUG; OPRM1 PROTEIN, HUMAN;

ARTICLE; BECK DEPRESSION INVENTORY; BODY REGIONS; CONTROLLED STUDY; DNA POLYMORPHISM; FAMILY HISTORY; FEMALE; FIBROMYALGIA; FIBROMYALGIA IMPACT QUESTIONNAIRE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; NAMED INVENTORIES, QUESTIONNAIRES AND RATING SCALES; PAIN ASSESSMENT; PAIN INTENSITY; PAIN SEVERITY; PRESSURE PAIN THRESHOLD; PRIORITY JOURNAL; TURK (PEOPLE); WIDESPREAD PAIN INDEX; ADULT; CASE CONTROL STUDY; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; PATHOPHYSIOLOGY; PHENOTYPE; PREDICTIVE VALUE; PROTECTION; RISK FACTOR; SEVERITY OF ILLNESS INDEX; SEX DIFFERENCE; TURKEY;

ADULT; CASE-CONTROL STUDIES; FEMALE; FIBROMYALGIA; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; PHENOTYPE; POLYMORPHISM, GENETIC; PREDICTIVE VALUE OF TESTS; PROTECTIVE FACTORS; RECEPTORS, OPIOID, MU; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SEX FACTORS; TURKEY;

EID: 84906937723     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-014-2995-1     Document Type: Article

References (23)

1. Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, Tugwell P, Campbell SM, Abeles M, Clark P et al (1990) The American College of Rheumatology 1990 criteria for the classification of fibromyalgia. Report of the multicenter criteria committee. Arthritis Rheum 33:160-172 (Pubitemid 20098653)
2. Martínez-Jauand M, Sitges C, Rodríguez V, Picornell A, Ramon M, Buskila D, Montoya P (2013) Pain sensitivity in fibromyalgia is associated with catechol-O-methyltransferase (COMT) gene. Eur J Pain 17:16-27
3. Bradley LA (2009) Pathophysiology of fibromyalgia. Am J Med 122:22-30
4. Buskila D, Sarzi-Puttini P, Ablin JN (2007) The genetics of fibromyalgia syndrome. Pharmacogenomics 8:67-74 (Pubitemid 46157758)
5. Tander B, Gunes S, Boke O, Alayli G, Kara N, Bagci H, Cantürk F (2008) Polymorphisms of the serotonin-2A receptor and cat-echol- Omethyltransferase genes: a study on fibromyalgia susceptibility. Rheumatol Int 28:685-691
6. Barbosa FR, Matsuda JB, Mazucato M, de Castro França S, Zingaretti SM, da Silva LM (2012) Influence of catechol-O-methyltransferase (COMT) gene polymorphisms in pain sensibility of Brazilian fibromialgia patients. Rheumatol Int 32:427-430
7. Finan PH, Zautra AJ, Davis MC, Lemery-Chalfant K (2010) Genetic influences on the dynamics of the pain and affect in fibromyalgia. Health Psychol 29:134-142
8. Lee YH, Choi SJ, Ji JD (2012) Candidate gene studies of fibromyalgia: a systematic review and meta-analysis. Rheumatol Int 32:417-426
9. Gracely RH, Petzke F, Wolf JM, Clauw DJ (2002) Functional magnetic resonance imaging evidence of augmented pain processing in fibromyalgia. Arthritis Rheum 46:1333-1343 (Pubitemid 34525843)
10. Umeda M, Corbin LW, Maluf KS (2013) Preliminary investigation of absent nociceptive flexion reflex responses among more symptomatic women with fibromyalgia syndrome. Rheumatol Int 33:2365-2372
11. Shabalina SA, Zaykin DV, Gris P, Ogurtsov AY, Gauthier J, Shibata K, Tchivileva IE, Belfer I, Mishra B, Kiselycznyk C, Wallace MR, Staud R, Spiridonov NA, Max MB, Goldman D, Fillingim RB, Maixner W, Diatchenko L (2009) Expansion of the human mu-opioid receptor gene architecture: novel functional variants. Hum Mol Genet 18:1037-1051
12. Pasternak GW (2010) Molecular insights into mu opioid pharmacology: from the clinic to the bench. Clin J Pain 26(Suppl 10):S3-S9
13. Bond C, LaForge KS, Tian M, Melia D, Zhang S, Borg L, Gong J, Schluger J, Strong JA, Leal SM, Tischfield JA, Kreek MJ, Yu L (1998) Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. Proc Natl Acad Sci USA 95:9608-9613 (Pubitemid 28506279)
14. Beyer A, Koch T, Schröder H, Schulz S, Höllt V (2004) Effect of the A118G polymorphism on binding affinity, potency and agonist-mediated endocytosis, desensitization, and resensitization of the human mu-opioid receptor. J Neurochem 89:553-560 (Pubitemid 38534141)
15. Zubieta JK, Dannals RF, Frost JJ (1999) Gender and age influences on human brain mu-opioid receptor binding measured by PET. Am J Psychiatry 156:842-848 (Pubitemid 29260337)
16. Mura E, Govoni S, Racchi M, Carossa V, Ranzani GN, Allegri M, van Schaik RH (2013) Consequences of the 118A>G polymorphism in the OPRM1 gene: translation from bench to bedside? J Pain Res. 6:331-353
17. Olsen MB, Jacobsen LM, Schistad EI, Pedersen LM, Rygh LJ, Røe C, Gjerstad J (2012) Pain intensity the first year after lumbar disc herniation is associated with the A118G polymorphism in the opioid Receptor Mu 1 gene: evidence of a sex and genotype interaction. J Neurosci 32(29):9831-9834
18. Walter C, Lötsch J (2009) Meta-analysis of the relevance of the OPRM1 118A. G genetic variant for pain treatment. Pain 146:270-275
19. Fillingim RB, Kaplan L, Staud R, Ness TJ, Glover TL, Campbell CM, Mogil JS, Wallace MR (2005) The A118G single nucleotide polymorphism of the mu-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans. J Pain 6:159-167 (Pubitemid 40365019)
20. Sia AT, Lim Y, Lim EC, Goh RW, Law HY, Landau R, Teo YY, Tan EC (2008) A118G single nucleotide polymorphism of human mu-opioid receptor gene influences pain perception and patient-controlled intravenous morphine consumption after intrathecal morphine for postcesarean analgesia. Anesthesiology 109:520-526
21. Chong RY, Oswald L, Yang X, Uhart M, Lin P-I, Swan GS (2006) The mu-opioid receptor polymorphism A118G predicts cortisol responses to naloxone and stress. Neuropsychopharmacology 31:204-211 (Pubitemid 43250957)
22. Bart G, LaForge KS, Borg L, Lily C, Ho A, Kreek MJ (2006) Altered levels of basal cortisol in healthy subjects with a 118G allele in exon 1 of the Mu opioid receptor gene. Neuropsychopharmacology 31:204-211
23. Katedoff D, Kosek E (2010) Evidence of reduced sympatho-adrenal and hypothalamic-pituitary activity during static muscular work in patients with fibromyalgia. J Rehabil Med 42:765-772