-
1
-
-
46049111766
-
Cancer Pain Relief and Palliative Care. Geneva, Switzerland: World Health Organization
-
WHO, Technical Report Series No 804
-
WHO. Cancer Pain Relief and Palliative Care. Geneva, Switzerland: World Health Organization, Technical Report Series No 804, 1990.
-
(1990)
-
-
-
3
-
-
0037758126
-
Morphine and alternative opioids in cancyer pain: The EAPC recommendations
-
Hanks, GW, Conno, F, Cherny, N, Hanna, M, Kalso, E, McQuay, HJ, et al. Morphine and alternative opioids in cancyer pain: the EAPC recommendations. Br J Cancer 2001; 84: 587-593.
-
(2001)
Br J Cancer
, vol.84
, pp. 587-593
-
-
Hanks, G.W.1
Conno, F.2
Cherny, N.3
Hanna, M.4
Kalso, E.5
McQuay, H.J.6
-
4
-
-
16344374909
-
Contribution to variability in response to opioids
-
Hanks, GW, Reid, C. Contribution to variability in response to opioids. Support Care Cancer 2005; 13: 145-152.
-
(2005)
Support Care Cancer
, vol.13
, pp. 145-152
-
-
Hanks, G.W.1
Reid, C.2
-
5
-
-
0035340444
-
Strategies to manage the adverse effects of oral morphine: An evidence-based report
-
Cherny, N, Ripamonti, C, Pereira, J, Davis, C, Fallon, M, McQuay, H, et al. Strategies to manage the adverse effects of oral morphine: an evidence-based report. J Clin Oncol 2001; 19: 2542-2554.
-
(2001)
J Clin Oncol
, vol.19
, pp. 2542-2554
-
-
Cherny, N.1
Ripamonti, C.2
Pereira, J.3
Davis, C.4
Fallon, M.5
McQuay, H.6
-
6
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander, ES, Linton, LM, Birren, B, Nusbaum, C, Zody, MC, Baldwin, J, et al. Initial sequencing and analysis of the human genome. Nature 2001; 409: 860-921.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
Nusbaum, C.4
Zody, M.C.5
Baldwin, J.6
-
7
-
-
0035895505
-
The sequence of the human genome
-
Venter, JC, Adams, MD, Myers, EW, Li, PW, Mural, RJ, Sutton, GG, et al. The sequence of the human genome. Science 2001; 291: 1304-1351.
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
Sutton, G.G.6
-
8
-
-
14644425293
-
Genetics and variability in opioid response
-
Stamer, UM, Bayerer, B, Stuber, F. Genetics and variability in opioid response. European Journal of Pain 2005; 9: 101-104.
-
(2005)
European Journal of Pain
, vol.9
, pp. 101-104
-
-
Stamer, U.M.1
Bayerer, B.2
Stuber, F.3
-
9
-
-
0025034181
-
Oral morphine in cancer pain: Influences on morphine and metabolite concentration
-
McQuay, HJ, Carroll, D, Faura, CC, Gavaghan, DJ, Hand, CW, Moore, RA. Oral morphine in cancer pain: influences on morphine and metabolite concentration. Clin Pharmacol Ther 1990; 48: 236-244.
-
(1990)
Clin Pharmacol Ther
, vol.48
, pp. 236-244
-
-
McQuay, H.J.1
Carroll, D.2
Faura, C.C.3
Gavaghan, D.J.4
Hand, C.W.5
Moore, R.A.6
-
10
-
-
0034086826
-
Pain intensity and side effects during titration of morphine to cancer patients using a fired schedule dose escalation
-
Klepstad, P, Kaasa, S, Skauge, M, Borchgrevink, PC. Pain intensity and side effects during titration of morphine to cancer patients using a fired schedule dose escalation. Acta Anaesthesiol Scand 2000; 44: 656-664.
-
(2000)
Acta Anaesthesiol Scand
, vol.44
, pp. 656-664
-
-
Klepstad, P.1
Kaasa, S.2
Skauge, M.3
Borchgrevink, P.C.4
-
11
-
-
0036205870
-
Symptomatology of cancer patients in palliative care: Content validation of self-assessment questionnaires against medical records
-
Stromgren, AS, Groenvold, M, Pedersen, L, Olsen, AK, Sjogren, P. Symptomatology of cancer patients in palliative care: content validation of self-assessment questionnaires against medical records. Eur J Cancer 2002; 38: 788-794.
-
(2002)
Eur J Cancer
, vol.38
, pp. 788-794
-
-
Stromgren, A.S.1
Groenvold, M.2
Pedersen, L.3
Olsen, A.K.4
Sjogren, P.5
-
12
-
-
34250688393
-
The adverse effects of morphine: A prospective survey of common symptoms during repeated dosing for chronic cancer pain
-
Glare, P, Walsh, D, Sheehan, D. The adverse effects of morphine: a prospective survey of common symptoms during repeated dosing for chronic cancer pain. Am J Hosp Palliat Care 2006; 23: 229-235.
-
(2006)
Am J Hosp Palliat Care
, vol.23
, pp. 229-235
-
-
Glare, P.1
Walsh, D.2
Sheehan, D.3
-
13
-
-
28444488984
-
Opioid-induced or pain relief-reduced symptoms in advanced cancer patients
-
Mercadante, S, Villari, P, Ferrera, P, Casuccio, A. Opioid-induced or pain relief-reduced symptoms in advanced cancer patients. Eur J Pain 2006; 10: 153-159.
-
(2006)
Eur J Pain
, vol.10
, pp. 153-159
-
-
Mercadante, S.1
Villari, P.2
Ferrera, P.3
Casuccio, A.4
-
14
-
-
33847648461
-
Pharmacogenetics of opioids
-
Somogyi, AA, Barratt, DT, Coller, JK. Pharmacogenetics of opioids. Clin Pharmacol Ther 2007; 81: 429-444.
-
(2007)
Clin Pharmacol Ther
, vol.81
, pp. 429-444
-
-
Somogyi, A.A.1
Barratt, D.T.2
Coller, J.K.3
-
15
-
-
45849088385
-
Candidate gene polymorphisms predicting individual sensitivity to opioids
-
Kasai, S, Hayashida, M, Sora, I, Ikeda, K. Candidate gene polymorphisms predicting individual sensitivity to opioids. Naunyn Schmiedebergs Arch Pharmacol. 2007.
-
(2007)
Naunyn Schmiedebergs Arch Pharmacol
-
-
Kasai, S.1
Hayashida, M.2
Sora, I.3
Ikeda, K.4
-
16
-
-
10044297116
-
Genetic predictors of the clinical response to opioid analgesics: Clinical utility and future perspectives
-
Lotsch, J, Skarke, C, Liefhold, J, Geisslinger, G. Genetic predictors of the clinical response to opioid analgesics: clinical utility and future perspectives. Clin Pharmacokinet 2004; 43: 983-1013.
-
(2004)
Clin Pharmacokinet
, vol.43
, pp. 983-1013
-
-
Lotsch, J.1
Skarke, C.2
Liefhold, J.3
Geisslinger, G.4
-
17
-
-
34848830072
-
Current evidence for a modulation of nociception by human genetic polymorphisms
-
Lotsch, J, Geisslinger, G. Current evidence for a modulation of nociception by human genetic polymorphisms. Pain 2007; 132: 18-22.
-
(2007)
Pain
, vol.132
, pp. 18-22
-
-
Lotsch, J.1
Geisslinger, G.2
-
18
-
-
46049084121
-
The genetics of pain
-
Mogil, JS, ed, IASP Press;, Seattle, WA, USA
-
Mogil, JS. The genetics of pain. In: Mogil, JS, (ed.) Progression in Pain Research and Management. Vol 28. IASP Press; 2004, Seattle, WA, USA.
-
(2004)
Progression in Pain Research and Management
, vol.28
-
-
Mogil, J.S.1
-
19
-
-
0034855786
-
The importance of cytochrome P450 monooxygenase CYP2D6 in palliative medicine
-
Davis, MP, Homsi, J. The importance of cytochrome P450 monooxygenase CYP2D6 in palliative medicine. Support Care Cancer 2001; 9: 442-451.
-
(2001)
Support Care Cancer
, vol.9
, pp. 442-451
-
-
Davis, M.P.1
Homsi, J.2
-
20
-
-
33748787999
-
Pharmacogenetics, drug-metabolizing enzymes, and clinical practice
-
Gardiner, SJ, Begg, EJ. Pharmacogenetics, drug-metabolizing enzymes, and clinical practice. Pharmacol Rev 2006; 58: 521-590.
-
(2006)
Pharmacol Rev
, vol.58
, pp. 521-590
-
-
Gardiner, S.J.1
Begg, E.J.2
-
22
-
-
24144470762
-
Morphine-6-glucuronide: Actions and mechanisms
-
Kilpatrick, GJ, Smith, TW. Morphine-6-glucuronide: actions and mechanisms. Med Res Rev 2005; 25: 521-544.
-
(2005)
Med Res Rev
, vol.25
, pp. 521-544
-
-
Kilpatrick, G.J.1
Smith, T.W.2
-
23
-
-
0036373740
-
Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy
-
Holthe, M, Klepstad, P, Zahlsen, K, Borchgrevink, PC, Hagen, L, Dale, O, et al. Morphine glucuronide-to-morphine plasma ratios are unaffected by the UGT2B7 H268Y and UGT1A1*28 polymorphisms in cancer patients on chronic morphine therapy. Eur J Clin Pharmacol 2002; 58: 353-356.
-
(2002)
Eur J Clin Pharmacol
, vol.58
, pp. 353-356
-
-
Holthe, M.1
Klepstad, P.2
Zahlsen, K.3
Borchgrevink, P.C.4
Hagen, L.5
Dale, O.6
-
24
-
-
0033760290
-
Polymorphisms in UDP glucuronosyltransferase genes: Functional consequences and clinical relevance
-
Mackenzie, PI, Miners, JO, McKinnon, RA. Polymorphisms in UDP glucuronosyltransferase genes: functional consequences and clinical relevance. Clin Chem Lab Med 2000; 38: 889-892.
-
(2000)
Clin Chem Lab Med
, vol.38
, pp. 889-892
-
-
Mackenzie, P.I.1
Miners, J.O.2
McKinnon, R.A.3
-
25
-
-
0038209379
-
A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine
-
Sawyer, MB, Innocenti, F, Das, S, Cheng, C, Ramirez, J, Pantle-Fisher, FH, et al. A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine. Clin Pharmacol Ther 2003; 73: 566-574.
-
(2003)
Clin Pharmacol Ther
, vol.73
, pp. 566-574
-
-
Sawyer, M.B.1
Innocenti, F.2
Das, S.3
Cheng, C.4
Ramirez, J.5
Pantle-Fisher, F.H.6
-
26
-
-
0037251316
-
Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: Identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients
-
Holthe, M, Rakvag, TN, Klepstad, P, Idle, JR, Kaasa, S, Krokan, HE, et al. Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients. Pharmacogenomics J 2003; 3: 17-26.
-
(2003)
Pharmacogenomics J
, vol.3
, pp. 17-26
-
-
Holthe, M.1
Rakvag, T.N.2
Klepstad, P.3
Idle, J.R.4
Kaasa, S.5
Krokan, H.E.6
-
27
-
-
27144529586
-
Clinical response to morphine in cancer patients and genetic variation in candidate genes
-
Ross, JR, Rutter, D, Welsh, K, Joel, SP, Goller, K, Wells, AU, et al. Clinical response to morphine in cancer patients and genetic variation in candidate genes. Pharmacogenomics J 2005; 5: 324-336.
-
(2005)
Pharmacogenomics J
, vol.5
, pp. 324-336
-
-
Ross, J.R.1
Rutter, D.2
Welsh, K.3
Joel, S.P.4
Goller, K.5
Wells, A.U.6
-
28
-
-
33646116562
-
Environmental and genetic factors associated with morphine response in the postoperative period
-
Coulbault, L, Beaussier, M, Verstuyft, C, Weickmans, H, Dubert, L, Tregouet, D, et al. Environmental and genetic factors associated with morphine response in the postoperative period. Clin Pharmacol Ther 2006; 79: 316-324.
-
(2006)
Clin Pharmacol Ther
, vol.79
, pp. 316-324
-
-
Coulbault, L.1
Beaussier, M.2
Verstuyft, C.3
Weickmans, H.4
Dubert, L.5
Tregouet, D.6
-
29
-
-
13144261678
-
Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: Possible implications for opiate addiction
-
Bond, C, LaForge, KS, Tian, M, Melia, D, Zhang, S, Borg, L, et al. Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. Proc Natl Acad Sci U S A 1998; 95: 9608-9613.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 9608-9613
-
-
Bond, C.1
LaForge, K.S.2
Tian, M.3
Melia, D.4
Zhang, S.5
Borg, L.6
-
30
-
-
34548653719
-
The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor
-
Kroslak, T, Laforge, KS, Gianotti, RJ, Ho, A, Nielsen, DA, Kreek, MJ. The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor. J Neurochem 2007; 103: 77-87.
-
(2007)
J Neurochem
, vol.103
, pp. 77-87
-
-
Kroslak, T.1
Laforge, K.S.2
Gianotti, R.J.3
Ho, A.4
Nielsen, D.A.5
Kreek, M.J.6
-
31
-
-
0036152705
-
The polymorphism A118G of the human mu-opioid receptor gene decreases the pupil constrictory effect of morphine-6-glucuronide but not that of morphine
-
Lotsch, J, Skarke, C, Grosch, S, Darimont, J, Schmidt, H, Geisslinger, G. The polymorphism A118G of the human mu-opioid receptor gene decreases the pupil constrictory effect of morphine-6-glucuronide but not that of morphine. Pharmacogenetics 2002; 12: 3-9.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 3-9
-
-
Lotsch, J.1
Skarke, C.2
Grosch, S.3
Darimont, J.4
Schmidt, H.5
Geisslinger, G.6
-
32
-
-
0037261291
-
Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers
-
Skarke, C, Darimont, J, Schmidt, H, Geisslinger, G, Lotsch, J. Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers. Clin Pharmacol Ther 2003; 73: 107-121.
-
(2003)
Clin Pharmacol Ther
, vol.73
, pp. 107-121
-
-
Skarke, C.1
Darimont, J.2
Schmidt, H.3
Geisslinger, G.4
Lotsch, J.5
-
33
-
-
30344473318
-
Modulation of the central nervous effects of levomethadone by genetic polymorphisms potentially affecting its metabolism, distribution, and drug action
-
Lotsch, J, Skarke, C, Wieting, J, Oertel, BG, Schmidt, H, Brockmoller, J, et al. Modulation of the central nervous effects of levomethadone by genetic polymorphisms potentially affecting its metabolism, distribution, and drug action. Clin Pharmacol Ther 2006; 79: 72-89.
-
(2006)
Clin Pharmacol Ther
, vol.79
, pp. 72-89
-
-
Lotsch, J.1
Skarke, C.2
Wieting, J.3
Oertel, B.G.4
Schmidt, H.5
Brockmoller, J.6
-
34
-
-
8544257029
-
The 118 A > G polymorphism in the human mu-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease
-
Klepstad, P, Rakvag, TT, Kaasa, S, Holthe, M, Dale, O, Borchgrevink, PC, et al. The 118 A > G polymorphism in the human mu-opioid receptor gene may increase morphine requirements in patients with pain caused by malignant disease. Acta Anaesthesiol Scand 2004; 48: 1232-1239.
-
(2004)
Acta Anaesthesiol Scand
, vol.48
, pp. 1232-1239
-
-
Klepstad, P.1
Rakvag, T.T.2
Kaasa, S.3
Holthe, M.4
Dale, O.5
Borchgrevink, P.C.6
-
35
-
-
14644441712
-
Polymorphism of mu-opioid receptor gene (OPRM1:c.118A>G) does not protect against opioid-induced respiratory depression despite reduced analgesic response
-
Romberg, RR, Olofsen, E, Bijl, H, Taschner, PE, Teppema, LJ, Sarton, EY, et al. Polymorphism of mu-opioid receptor gene (OPRM1:c.118A>G) does not protect against opioid-induced respiratory depression despite reduced analgesic response. Anesthesiology 2005; 102: 522-530.
-
(2005)
Anesthesiology
, vol.102
, pp. 522-530
-
-
Romberg, R.R.1
Olofsen, E.2
Bijl, H.3
Taschner, P.E.4
Teppema, L.J.5
Sarton, E.Y.6
-
36
-
-
33745813212
-
Association of mu-opioid receptor gene polymorphism (A118G) with variations in morphine consumption for analgesia after total knee arthroplasty
-
Chou, WY, Yang, LC, Lu, HF, Ko, JY, Wang, CH, Lin, SH, et al. Association of mu-opioid receptor gene polymorphism (A118G) with variations in morphine consumption for analgesia after total knee arthroplasty. Acta Anaesthesiol Scand 2006; 50: 787-792.
-
(2006)
Acta Anaesthesiol Scand
, vol.50
, pp. 787-792
-
-
Chou, W.Y.1
Yang, L.C.2
Lu, H.F.3
Ko, J.Y.4
Wang, C.H.5
Lin, S.H.6
-
37
-
-
33746608902
-
Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy
-
Chou, WY, Wang, CH, Liu, PH, Liu, CC, Tseng, CC, Jawan, B. Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy. Anesthesiology 2006; 105: 334-337.
-
(2006)
Anesthesiology
, vol.105
, pp. 334-337
-
-
Chou, W.Y.1
Wang, C.H.2
Liu, P.H.3
Liu, C.C.4
Tseng, C.C.5
Jawan, B.6
-
38
-
-
33747126106
-
The mu-opioid receptor gene polymorphism 118A>G depletes alfentanil-induced analgesia and protects against respiratory depression in homozygous carriers
-
Oertel, BG, Schmidt, R, Schneider, A, Geisslinger, G, Lotsch, J. The mu-opioid receptor gene polymorphism 118A>G depletes alfentanil-induced analgesia and protects against respiratory depression in homozygous carriers. Pharmacogenet Genomics 2006; 16: 625-636.
-
(2006)
Pharmacogenet Genomics
, vol.16
, pp. 625-636
-
-
Oertel, B.G.1
Schmidt, R.2
Schneider, A.3
Geisslinger, G.4
Lotsch, J.5
-
39
-
-
42249106004
-
Association of ABCB1/MDR1 and OPRM1 Gene Polymorphisms With Morphine Pain Relief
-
Epub ahead of print
-
Campa, D, Gioia, A, Tomei, A, Poli, P, Barale, R. Association of ABCB1/MDR1 and OPRM1 Gene Polymorphisms With Morphine Pain Relief. Clin Pharmacol Ther. 2007 [Epub ahead of print]
-
(2007)
Clin Pharmacol Ther
-
-
Campa, D.1
Gioia, A.2
Tomei, A.3
Poli, P.4
Barale, R.5
-
40
-
-
13244298667
-
Are [mu]-opioid receptor polymorphisms important for clinical opioid therapy
-
Lotsch, J, Geisslinger, G. Are [mu]-opioid receptor polymorphisms important for clinical opioid therapy. Trends in Molecular Medicine 2005; 11: 82-89.
-
(2005)
Trends in Molecular Medicine
, vol.11
, pp. 82-89
-
-
Lotsch, J.1
Geisslinger, G.2
-
41
-
-
0037458277
-
COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor
-
Zubieta, JK, Heitzeg, MM, Smith, YR, Bueller, JA, Xu, K, Xu, Y, et al. COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor. Science 2003; 299: 1240-1243.
-
(2003)
Science
, vol.299
, pp. 1240-1243
-
-
Zubieta, J.K.1
Heitzeg, M.M.2
Smith, Y.R.3
Bueller, J.A.4
Xu, K.5
Xu, Y.6
-
42
-
-
19944427292
-
Genetic basis for individual variations in pain perception and the development of a chronic pain condition
-
Diatchenko, L, Slade, GD, Nackley, AG, Bhalang, K, Sigurdsson, A, Belfer, I, et al. Genetic basis for individual variations in pain perception and the development of a chronic pain condition. Hum Mol Genet 2005; 14: 135-143.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 135-143
-
-
Diatchenko, L.1
Slade, G.D.2
Nackley, A.G.3
Bhalang, K.4
Sigurdsson, A.5
Belfer, I.6
-
43
-
-
33750697663
-
Catechol-O-methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli
-
Diatchenko, L, Nackley, AG, Slade, GD, Bhalang, K, Belyfer, I, Max, MB, et al. Catechol-O-methyltransferase gene polymorphisms are associated with multiple pain-evoking stimuli. Pain 2006; 125: 216-224.
-
(2006)
Pain
, vol.125
, pp. 216-224
-
-
Diatchenko, L.1
Nackley, A.G.2
Slade, G.D.3
Bhalang, K.4
Belyfer, I.5
Max, M.B.6
-
44
-
-
33747357980
-
Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans
-
Kim, H, Lee, H, Rowan, J, Brahim, J, Dionne, RA. Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans. Mol Pain 2006; 2: 24.
-
(2006)
Mol Pain
, vol.2
, pp. 24
-
-
Kim, H.1
Lee, H.2
Rowan, J.3
Brahim, J.4
Dionne, R.A.5
-
45
-
-
20444451123
-
The Val158Met polymorphism of the human catechol-Oy-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients
-
Rakvag, TT, Klepstad, P, Baar, C, Kvam, TM, Dale, O, Kaasa, S, et al. The Val158Met polymorphism of the human catechol-Oy-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients. Pain 2005; 116: 73-78.
-
(2005)
Pain
, vol.116
, pp. 73-78
-
-
Rakvag, T.T.1
Klepstad, P.2
Baar, C.3
Kvam, T.M.4
Dale, O.5
Kaasa, S.6
-
46
-
-
33746012401
-
Postoperative pain, morphine consumption, and genetic polymorphism of IL-1beta and IL-1 receptor antagonist
-
Bessler, H, Shavit, Y, Mayburd, E, Smirnov, G, Beilin, B. Postoperative pain, morphine consumption, and genetic polymorphism of IL-1beta and IL-1 receptor antagonist. Neurosci Lett 2006; 404: 154-158.
-
(2006)
Neurosci Lett
, vol.404
, pp. 154-158
-
-
Bessler, H.1
Shavit, Y.2
Mayburd, E.3
Smirnov, G.4
Beilin, B.5
-
47
-
-
0032779132
-
Genetic studies of the human melanocortin-1 receptor
-
Rees, JL, Birch-Machin, M, Flanagan, N, Healy, E, Phillips, S, Todd, C. Genetic studies of the human melanocortin-1 receptor. Ann N Y Acad Sci 1999; 885: 134-142.
-
(1999)
Ann N Y Acad Sci
, vol.885
, pp. 134-142
-
-
Rees, J.L.1
Birch-Machin, M.2
Flanagan, N.3
Healy, E.4
Phillips, S.5
Todd, C.6
-
48
-
-
0028885627
-
Expression of melanocortin 1 receptor in periaqueductal gray matter
-
Xia, Y, Wikberg, JE, Chhajlani, V. Expression of melanocortin 1 receptor in periaqueductal gray matter. Neuroreport 1995; 6: 2193-2196.
-
(1995)
Neuroreport
, vol.6
, pp. 2193-2196
-
-
Xia, Y.1
Wikberg, J.E.2
Chhajlani, V.3
-
49
-
-
0021288912
-
Endogenous pain control systems: Brainstem spinal pathways and endorphin circuitry
-
Basbaum, AI, Fields, HL. Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. Annu Rev Neurosci 1984; 7: 309-338.
-
(1984)
Annu Rev Neurosci
, vol.7
, pp. 309-338
-
-
Basbaum, A.I.1
Fields, H.L.2
-
50
-
-
0344341625
-
The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans
-
Mogil, JS, Wilson, SG, Chesler, EJ, Rankin, AL, Nemmani, KV, Lariviere, WR, et al. The melanocortin-1 receptor gene mediates female-specific mechanisms of analgesia in mice and humans. Proc Natl Acad Sci U S A 2003; 100: 4867-4872.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 4867-4872
-
-
Mogil, J.S.1
Wilson, S.G.2
Chesler, E.J.3
Rankin, A.L.4
Nemmani, K.V.5
Lariviere, W.R.6
-
51
-
-
22244492308
-
Melanocortin-1 receptor gene variants affect pain and mu-opioid analgesia in mice and humans
-
Mogil, JS, Ritchie, J, Smith, SB, Strasburg, K, Kaplan, L, Wallace, MR, et al. Melanocortin-1 receptor gene variants affect pain and mu-opioid analgesia in mice and humans. J Med Genet 2005; 42: 583-587.
-
(2005)
J Med Genet
, vol.42
, pp. 583-587
-
-
Mogil, J.S.1
Ritchie, J.2
Smith, S.B.3
Strasburg, K.4
Kaplan, L.5
Wallace, M.R.6
-
52
-
-
0035118510
-
Transport of opioids from the brain to the periphery by P-glycoprotein: Peripheral actions of central drugs
-
King, M, Su, W, Chang, A, Zuckerman, A, Pasternak, GW. Transport of opioids from the brain to the periphery by P-glycoprotein: peripheral actions of central drugs. Nat Neurosci 2001; 4: 268-274.
-
(2001)
Nat Neurosci
, vol.4
, pp. 268-274
-
-
King, M.1
Su, W.2
Chang, A.3
Zuckerman, A.4
Pasternak, G.W.5
-
53
-
-
0036206856
-
Interaction of morphine, fentanyl, sufentanil, alfentanil, and loperamide with the efflux drug transporter P-glycoprotein
-
Wandel, C, Kim, R, Wood, M, Wood, A. Interaction of morphine, fentanyl, sufentanil, alfentanil, and loperamide with the efflux drug transporter P-glycoprotein. Anesthesiology 2002; 96: 913-920.
-
(2002)
Anesthesiology
, vol.96
, pp. 913-920
-
-
Wandel, C.1
Kim, R.2
Wood, M.3
Wood, A.4
-
54
-
-
0034016617
-
Opiate-induced analgesia is increased and prolonged in mice lacking P-glycoprotein
-
Thompson, SJ, Koszdin, K, Bernards, CM. Opiate-induced analgesia is increased and prolonged in mice lacking P-glycoprotein. Anesthesiology 2000; 92: 1392-1399.
-
(2000)
Anesthesiology
, vol.92
, pp. 1392-1399
-
-
Thompson, S.J.1
Koszdin, K.2
Bernards, C.M.3
-
55
-
-
0029786352
-
Evidence for P-glycoprotein-modulated penetration, of morphine-6-glucuronide into brain capillary endothelium
-
Huwyler, J, Drewe, J, Klusemann, C, Fricker, G. Evidence for P-glycoprotein-modulated penetration, of morphine-6-glucuronide into brain capillary endothelium. Br J Pharmacol 1996; 118: 1879-1885.
-
(1996)
Br J Pharmacol
, vol.118
, pp. 1879-1885
-
-
Huwyler, J.1
Drewe, J.2
Klusemann, C.3
Fricker, G.4
-
56
-
-
0030879184
-
Loss of analgesic effect of morphine due coadministration of rifampin
-
Fromm, MF, Eckhardt, K, Li, SX, Schanzle, G, Hofmann, U, Mikus, G, et al. Loss of analgesic effect of morphine due coadministration of rifampin. Pain 1997; 72: 261-267.
-
(1997)
Pain
, vol.72
, pp. 261-267
-
-
Fromm, M.F.1
Eckhardt, K.2
Li, S.X.3
Schanzle, G.4
Hofmann, U.5
Mikus, G.6
-
57
-
-
0347504918
-
Role of P-glycoprotein in the intestinal absorption and clinical effects of morphine
-
Kharasch, ED, Hoffer, C, Whittington, D, Sheffels, P. Role of P-glycoprotein in the intestinal absorption and clinical effects of morphine. Clin Pharmacol Ther 2003; 74: 543-554.
-
(2003)
Clin Pharmacol Ther
, vol.74
, pp. 543-554
-
-
Kharasch, E.D.1
Hoffer, C.2
Whittington, D.3
Sheffels, P.4
-
58
-
-
34249794271
-
Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene
-
Reyes-Gibby, CC, Shete, S, Rakvag, T, Bhat, SV, Skorpen, F, Bruera, E, et al. Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene. Pain 2007; 130: 25-30.
-
(2007)
Pain
, vol.130
, pp. 25-30
-
-
Reyes-Gibby, C.C.1
Shete, S.2
Rakvag, T.3
Bhat, S.V.4
Skorpen, F.5
Bruera, E.6
-
59
-
-
0036154953
-
A polymorphism (A118G) in the mu-opioid receptor gene affects the response to morphine-6-glucuronide in humans
-
Hollt, V. A polymorphism (A118G) in the mu-opioid receptor gene affects the response to morphine-6-glucuronide in humans. Pharmacogenetics 2002; 12: 1-2.
-
(2002)
Pharmacogenetics
, vol.12
, pp. 1-2
-
-
Hollt, V.1
-
60
-
-
0036792226
-
Does the A118G polymorphism at the mu-opioid receptor gene protect against morphine-6-glucuronide toxicity
-
Lotsch, J, Zimmermann, M, Darimont, J, Marx, C, Dudziak, R, Skarke, C, et al. Does the A118G polymorphism at the mu-opioid receptor gene protect against morphine-6-glucuronide toxicity. Anesthesiology 2002; 97: 814-819.
-
(2002)
Anesthesiology
, vol.97
, pp. 814-819
-
-
Lotsch, J.1
Zimmermann, M.2
Darimont, J.3
Marx, C.4
Dudziak, R.5
Skarke, C.6
-
61
-
-
33947391399
-
Genetic Polymorphisms in the ABCB1 Gene and the Effects of Fentanyl in Koreans
-
Park, HJ, Shinn, HK, Ryu, SH, Lee, HS, Park, CS, Kang, JH. Genetic Polymorphisms in the ABCB1 Gene and the Effects of Fentanyl in Koreans. Clin Pharmacol Ther 2006; 81: 539-546.
-
(2006)
Clin Pharmacol Ther
, vol.81
, pp. 539-546
-
-
Park, H.J.1
Shinn, H.K.2
Ryu, S.H.3
Lee, H.S.4
Park, C.S.5
Kang, J.H.6
-
62
-
-
0027407565
-
Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
-
Strittmatter, WJ, Saunders, AM, Schmechel, D, Pericak-Vance, M, Enghild, J, Salvesen, GS, et al. Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci U S A 1993; 90: 1977-1981.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 1977-1981
-
-
Strittmatter, W.J.1
Saunders, A.M.2
Schmechel, D.3
Pericak-Vance, M.4
Enghild, J.5
Salvesen, G.S.6
-
63
-
-
0027327267
-
Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease
-
Saunders, AM, Strittmatter, WJ, Schmechel, D, George-Hyslop, PH, Pericak-Vance, MA, Joo, SH, et al. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993; 43: 1467-1472.
-
(1993)
Neurology
, vol.43
, pp. 1467-1472
-
-
Saunders, A.M.1
Strittmatter, W.J.2
Schmechel, D.3
George-Hyslop, P.H.4
Pericak-Vance, M.A.5
Joo, S.H.6
-
64
-
-
0031946960
-
Apolipoprotein E and the CNS response to injury
-
Laskowitz, DT, Horsburgh, K, Roses, AD. Apolipoprotein E and the CNS response to injury. J Cereb Blood Flow Metab 1998; 18: 465-471.
-
(1998)
J Cereb Blood Flow Metab
, vol.18
, pp. 465-471
-
-
Laskowitz, D.T.1
Horsburgh, K.2
Roses, A.D.3
-
65
-
-
0036598957
-
Apolipoproteins and aging: Emerging mechanisms
-
Smith, JD. Apolipoproteins and aging: emerging mechanisms. Ageing Res Rev 2002; 1: 345-365.
-
(2002)
Ageing Res Rev
, vol.1
, pp. 345-365
-
-
Smith, J.D.1
-
66
-
-
35748971011
-
Association between apolipoprotein E4 and cognitive decline in elderly adults
-
Packard, CJ, Westendorp, RG, Stott, DJ, Caslake, MJ, Murray, HM, Shepherd, J, et al. Association between apolipoprotein E4 and cognitive decline in elderly adults. J Am Geriatr Soc 2007; 55: 1777-1785.
-
(2007)
J Am Geriatr Soc
, vol.55
, pp. 1777-1785
-
-
Packard, C.J.1
Westendorp, R.G.2
Stott, D.J.3
Caslake, M.J.4
Murray, H.M.5
Shepherd, J.6
-
67
-
-
34247202571
-
Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain
-
Liang, WS, Dunckley, T, Beach, TG, Grover, A, Mastroeni, D, Walker, DG, et al. Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. Physiol Genomics 2007; 28: 311-322.
-
(2007)
Physiol Genomics
, vol.28
, pp. 311-322
-
-
Liang, W.S.1
Dunckley, T.2
Beach, T.G.3
Grover, A.4
Mastroeni, D.5
Walker, D.G.6
-
68
-
-
34250891312
-
Remifentanil-induced cerebral blood flow effects in normal humans: Dose and ApoE genotype
-
Kofke, WA, Blisitt, PA, Rao, H, Wang, J, Addya, K, Detre, J. Remifentanil-induced cerebral blood flow effects in normal humans: Dose and ApoE genotype. Anesthesia and Analgesia 2007; 105: 167-175.
-
(2007)
Anesthesia and Analgesia
, vol.105
, pp. 167-175
-
-
Kofke, W.A.1
Blisitt, P.A.2
Rao, H.3
Wang, J.4
Addya, K.5
Detre, J.6
-
69
-
-
31044445939
-
No pain relief from morphine? Individual variation in sensitivity to morphine and the need to switch to an alternative opioid in cancer patients
-
Riley, J, Ross, JR, Rutter, D, Wells, AU, Goller, K, du Bois, R, et al. No pain relief from morphine? Individual variation in sensitivity to morphine and the need to switch to an alternative opioid in cancer patients. Supportive Care in Cancer 2006; 14: 56-64.
-
(2006)
Supportive Care in Cancer
, vol.14
, pp. 56-64
-
-
Riley, J.1
Ross, J.R.2
Rutter, D.3
Wells, A.U.4
Goller, K.5
du Bois, R.6
-
70
-
-
0032436459
-
Effects of blocking CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone
-
Heiskanen, T, Olkkola, KT, Kalso, E. Effects of blocking CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone. Clin Pharmacol Ther 1998; 64: 603-611.
-
(1998)
Clin Pharmacol Ther
, vol.64
, pp. 603-611
-
-
Heiskanen, T.1
Olkkola, K.T.2
Kalso, E.3
-
71
-
-
0042634370
-
Adverse drug reactions to oxycodone and hydrocodone in CYP2D6 ultra-rapid metabolizers
-
de Leon, J, Dinsmore, L, Wedlund, P. Adverse drug reactions to oxycodone and hydrocodone in CYP2D6 ultra-rapid metabolizers. J Clin Psychopharmacol 2003; 23: 420-421.
-
(2003)
J Clin Psychopharmacol
, vol.23
, pp. 420-421
-
-
de Leon, J.1
Dinsmore, L.2
Wedlund, P.3
-
72
-
-
36348941795
-
Complicated Pain Management in a CYP450 2D6 Poor Metabolizer
-
Foster, A, Mobley, E, Wang, Z. Complicated Pain Management in a CYP450 2D6 Poor Metabolizer. Pain Pract 2007; 7: 352-356.
-
(2007)
Pain Pract
, vol.7
, pp. 352-356
-
-
Foster, A.1
Mobley, E.2
Wang, Z.3
-
73
-
-
33745652413
-
Response to hydrocodone, codeine and oxycodone in a CYP2D6 poor metabolizer
-
Susce, MT, Murray-Carmichael, E, de Leon, J. Response to hydrocodone, codeine and oxycodone in a CYP2D6 poor metabolizer. Prog Neuropsychopharmacol Biol Psychiatry 2006; 30: 1356-1358.
-
(2006)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.30
, pp. 1356-1358
-
-
Susce, M.T.1
Murray-Carmichael, E.2
de Leon, J.3
-
74
-
-
0036825844
-
Pharmacogenomics as molecular autopsy for postmortem forensic toxicology: Genotyping cytochrome P450 2D6 for oxycodone cases
-
Jannetto, PJ, Wong, SH, Gock, SB, Laleli-Sahin, E, Schur, BC, Jentzen, JM. Pharmacogenomics as molecular autopsy for postmortem forensic toxicology: genotyping cytochrome P450 2D6 for oxycodone cases. J Anal Toxicol 2002; 26: 438-447.
-
(2002)
J Anal Toxicol
, vol.26
, pp. 438-447
-
-
Jannetto, P.J.1
Wong, S.H.2
Gock, S.B.3
Laleli-Sahin, E.4
Schur, B.C.5
Jentzen, J.M.6
-
75
-
-
29144447977
-
Pharmacogenomics as molecular autopsy for forensic toxicology: Genotyping cytochrome P450 3A4*1B and 3A5*3 for 25 fentanyl cases
-
Jin, M, Gock, SB, Jannetto, PJ, Jentzen, JM, Wong, SH. Pharmacogenomics as molecular autopsy for forensic toxicology: genotyping cytochrome P450 3A4*1B and 3A5*3 for 25 fentanyl cases. J Anal Toxicol 2005; 29: 590-598.
-
(2005)
J Anal Toxicol
, vol.29
, pp. 590-598
-
-
Jin, M.1
Gock, S.B.2
Jannetto, P.J.3
Jentzen, J.M.4
Wong, S.H.5
-
76
-
-
0344950514
-
Sequence variability and candidate gene analysis in two cancer patients with complex clinical outcomes during morphine therapy
-
Hirota, T, Ieiri, I, Takane, H, Sano, H, Kawamoto, K, Aono, H, et al. Sequence variability and candidate gene analysis in two cancer patients with complex clinical outcomes during morphine therapy. Drug Metab Dispos 2003; 31: 677-680.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 677-680
-
-
Hirota, T.1
Ieiri, I.2
Takane, H.3
Sano, H.4
Kawamoto, K.5
Aono, H.6
-
77
-
-
0037868158
-
Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients
-
Tremblay, PB, Kaiser, R, Sezer, O, Rosler, N, Schelenz, C, Possinger, K, et al. Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients. J Clin Oncol 2003; 21: 2147-2155.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2147-2155
-
-
Tremblay, P.B.1
Kaiser, R.2
Sezer, O.3
Rosler, N.4
Schelenz, C.5
Possinger, K.6
-
79
-
-
33745780298
-
A clinical genetic method to identify mechanisms by which pain causes depression and anxiety
-
Max, MB, Wu, TX, Atlas, SJ, Edwards, RR, Haythornthwaite, JA, Bollettino, AF, et al. A clinical genetic method to identify mechanisms by which pain causes depression and anxiety. Mol Pain 2006; 2: 14.
-
(2006)
Mol Pain
, vol.2
, pp. 14
-
-
Max, M.B.1
Wu, T.X.2
Atlas, S.J.3
Edwards, R.R.4
Haythornthwaite, J.A.5
Bollettino, A.F.6
-
80
-
-
0038662987
-
Sex differences in opioid analgesia: "from mouse to man
-
Craft, RM. Sex differences in opioid analgesia: "from mouse to man". Clin J Pain 2003; 19: 175-186.
-
(2003)
Clin J Pain
, vol.19
, pp. 175-186
-
-
Craft, R.M.1
-
81
-
-
0033999331
-
Drug interactions in palliative care
-
Bernard, SA, Bruera, E. Drug interactions in palliative care. J Clin Oncol 2000; 18: 1780-1799.
-
(2000)
J Clin Oncol
, vol.18
, pp. 1780-1799
-
-
Bernard, S.A.1
Bruera, E.2
|