The atherogenic effects of serum amyloid A are potentially mediated via inflammation and apoptosis

Journal of Atherosclerosis and Thrombosis

Volumn 21, Issue 8, 2014, Pages 854-867

  Tan, Si Zhen ^a,b   Ooi, Delicia Shu Qin ^a,b   Shen, Han Ming ^a   Heng, Chew Kiat ^a,b  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY HEALTH SYSTEM   (Singapore)

Author keywords

Apoptosis; Atherosclerosis; Inflammation; NF B; Serum amyloid A (SAA)

Indexed keywords

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; A20 PROTEIN; CASPASE 3; CASPASE 8; CASPASE 9; FAS ANTIGEN; GELATINASE B; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; PEPTIDES AND PROTEINS; PROTEIN BCL 2; SERUM AMYLOID A; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOTAGMIN I; THROMBOPLASTIN; UNCLASSIFIED DRUG; AUTACOID; MESSENGER RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; ATHEROGENESIS; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; INFLAMMATION; MTT ASSAY; NONHUMAN; PATHOGENESIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; ATHEROSCLEROSIS; CELL PROLIFERATION; COMPLICATION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MACROPHAGE; METABOLISM; MOUSE; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; APOPTOSIS; ATHEROSCLEROSIS; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; MACROPHAGES; MICE; NF-KAPPA B; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SERUM AMYLOID A PROTEIN;

EID: 84906820765     PISSN: 13403478     EISSN: 18803873     Source Type: Journal    
DOI: 10.5551/jat.22665     Document Type: Article

References (52)

1. Halvorsen B, Otterdal K, Dahl TB, Skjelland M, Gullestad L, Oie E, Aukrust P: Atherosclerotic plaque stability--what determines the fate of a plaque ? Prog Cardiovasc Dis, 2008; 51: 183-194
2. Ramsey SA, Gold ES, Aderem A: A systems biology approach to understanding atherosclerosis. EMBO molecular medicine, 2010; 2: 79-89
3. Libby P: Atherosclerosis: the new view. Sci Am, 2002; 286: 46-55
4. Dabek J, Kulach A, Gasior Z: Nuclear factor kappa-lightchain-enhancer of activated B cells (NF-kappaB): a new potential therapeutic target in atherosclerosis? Pharmacological reports: PR, 2010; 62: 778-783
5. Erren M, Reinecke H, Junker R, Fobker M, Schulte H, Schurek JO, Kropf J, Kerber S, Breithardt G, Assmann G, Cullen P: Systemic inflammatory parameters in patients with atherosclerosis of the coronary and peripheral arteries. Arteriosclerosis, thrombosis, and vascular biology, 1999; 19: 2355-2363
6. Moreno PR, Falk E, Palacios IF, Newell JB, Fuster V, Fallon JT: Macrophage infiltration in acute coronary syndromes. Implications for plaque rupture. Circulation, 1994; 90: 775-778
7. Poston RN, Haskard DO, Coucher JR, Gall NP, Johnson Tidey RR: Expression of intercellular adhesion molecule-1 in atherosclerotic plaques. Am J Pathol, 1992; 140: 665-673
8. Kunte H, Amberger N, Busch MA, Ruckert RI, Meiners S, Harms L: Markers of instability in high-risk carotid plaques are reduced by statins. J Vasc Surg, 2008; 47: 513-522
9. Nemerson Y: Tissue factor: then and now. Thromb Haemost, 1995; 74: 180-184
10. Song C, Shen Y, Yamen E, Hsu K, Yan W, Witting PK, Geczy CL, Freedman SB: Serum amyloid A may potentiate prothrombotic and proinflammatory events in acute coronary syndromes. Atherosclerosis, 2009; 202: 596-604
11. Urieli-Shoval S, Linke RP, Matzner Y: Expression and function of serum amyloid A, a major acute-phase protein, in normal and disease states. Current opinion in hematology, 2000; 7: 64-69
12. Hatanaka E, Pereira Ribeiro F, Campa A: The acute phase protein serum amyloid A primes neutrophils. FEMS Immunol Med Microbiol, 2003; 38: 81-84
13. He R, Sang H, Ye RD: Serum amyloid A induces IL-8 secretion through a G protein-coupled receptor, FPRL1/ LXA4R. Blood, 2003; 101: 1572-1581
14. Sandri S, Hatanaka E, Franco AG, Pedrosa AM, Monteiro HP, Campa A: Serum amyloid A induces CCL20 secretion in mononuclear cells through MAPK (p38 and ERK1/2) signaling pathways. Immunol Lett, 2008; 121: 22-26
15. Song C, Hsu K, Yamen E, Yan W, Fock J, Witting PK, Geczy CL, Freedman SB: Serum amyloid A induction of cytokines in monocytes/macrophages and lymphocytes. Atherosclerosis, 2009; 207: 374-383
16. Wilson HM: Macrophages heterogeneity in atherosclerosis - implications for therapy. J Cell Mol Med, 2010; 14: 2055-2065
17. Kutuk O, Basaga H: Inflammation meets oxidation: NF-kappaB as a mediator of initial lesion development in atherosclerosis. Trends Mol Med, 2003; 9: 549-557
18. Li H, Ooi SQ, Heng CK: The role of NF-small ka, CyrillicB in SAA-induced peroxisome proliferator-activated receptor gamma activation. Atherosclerosis, 2013; 227: 72-78
19. Yuan D, Pan Y, Zhang J, Shao C: Role of nuclear factor-kappaB and P53 in radioadaptive response in Chang live cells. Mutat Res, 2010; 688: 66-71
20. Baker RG, Hayden MS, Ghosh S: NF-kappaB, inflammation, and metabolic disease. Cell Metab, 2011; 13: 11-22
21. Jijon HB, Madsen KL, Walker JW, Allard B, Jobin C: Serum amyloid A activates NF-kappaB and proinflammatory gene expression in human and murine intestinal epithelial cells. Eur J Immunol, 2005; 35: 718-726
22. Clarke MC, Bennett MR: Cause or consequence: what does macrophage apoptosis do in atherosclerosis ? Arterioscler Thromb Vasc Biol, 2009; 29: 153-155
23. Guevara NV, Chen KH, Chan L: Apoptosis in atherosclerosis: pathological and pharmacological implications. Pharmacol Res, 2001; 44: 59-71
24. Kockx MM, Herman AG: Apoptosis in atherosclerosis: beneficial or detrimental? Cardiovasc Res, 2000; 45: 736-746
25. Mercer J, Mahmoudi M, Bennett M: DNA damage, p53, apoptosis and vascular disease. Mutat Res, 2007; 621: 75-86
26. de Nigris F, Lerman A, Ignarro LJ, Williams-Ignarro S, Sica V, Baker AH, Lerman LO, Geng YJ, Napoli C: Oxidation-sensitive mechanisms, vascular apoptosis and ath erosclerosis. Trends Mol Med, 2003; 9: 351-359
27. Kho Y, Kim S, Yoon BS, Moon JH, Kim B, Kwak S, Woo J, Oh S, Hong K, Kim S, Kim H, You S, Choi Y: Induction of serum amyloid A genes is associated with growth and apoptosis of HC11 mammary epithelial cells. Biosci Biotechnol Biochem, 2008; 72: 70-81
28. Jo SH, Yun J, Kim JM, Lee C, Baek SH, Bae YS: Serum amyloid A induces WISH cell apoptosis. Acta Pharmacol Sin, 2007; 28: 73-80
29. Filep JG, El Kebir D: Serum amyloid A as a marker and mediator of acute coronary syndromes. Future Cardiol, 2008; 4: 495-504
30. Choy JC, Granville DJ, Hunt DW, McManus BM: Endothelial cell apoptosis: biochemical characteristics and potential implications for atherosclerosis. J Mol Cell Cardiol, 2001; 33: 1673-1690
31. Barry M, Heibein JA, Pinkoski MJ, Lee SF, Moyer RW, Green DR, Bleackley RC: Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid. Mol Cell Biol, 2000; 20: 3781-3794
32. Carter BZ, Gronda M, Wang Z, Welsh K, Pinilla C, Andreeff M, Schober WD, Nefzi A, Pond GR, Mawji IA, Houghten RA, Ostresh J, Brandwein J, Minden MD, Schuh AC, Wells RA, Messner H, Chun K, Reed JC, Schimmer AD: Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells. Blood, 2005; 105: 4043-4050
33. Chen T, Pengetnze Y, Taylor CC: Src inhibition enhances paclitaxel cytotoxicity in ovarian cancer cells by caspase-9independent activation of caspase-3. Mol Cancer Ther, 2005; 4: 217-224
34. Beg AA, Baltimore D: An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science, 1996; 274: 782-784
35. Van Antwerp DJ, Martin SJ, Kafri T, Green DR, Verma IM: Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science, 1996; 274: 787-789
36. Hettmann T, DiDonato J, Karin M, Leiden JM: An essential role for nuclear factor kappaB in promoting double positive thymocyte apoptosis. J Exp Med, 1999; 189: 145-158
37. Kaltschmidt B, Kaltschmidt C, Hofmann TG, Hehner SP, Droge W, Schmitz ML: The pro- or anti-apoptotic function of NF-kappaB is determined by the nature of the apoptotic stimulus. Eur J Biochem, 2000; 267: 3828-3835
38. Won M, Park KA, Byun HS, Sohn KC, Kim YR, Jeon J, Hong JH, Park J, Seok JH, Kim JM, Yoon WH, Jang IS, Shen HM, Liu ZG, Hur GM: Novel anti-apoptotic mechanism of A20 through targeting ASK1 to suppress TNF-induced JNK activation. Cell Death Differ, 2010; 17: 1830-1841
39. Dhanasekaran DN, Reddy EP: JNK signaling in apoptosis. Oncogene, 2008; 27: 6245-6251
40. Willis S, Day CL, Hinds MG, Huang DC: The Bcl-2- regulated apoptotic pathway. J Cell Sci, 2003; 116: 4053-4056
41. Zhang XD, Wang Y, Wu JC, Lin F, Han R, Han F, Fukunaga K, Qin ZH: Down-regulation of Bcl-2 enhances autophagy activation and cell death induced by mitochondrial dysfunction in rat striatum. Journal of neuroscience research, 2009; 87: 3600-3610
42. Goping IS, Barry M, Liston P, Sawchuk T, Constantinescu G, Michalak KM, Shostak I, Roberts DL, Hunter AM, Korneluk R, Bleackley RC: Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition. Immunity, 2003; 18: 355-365
43. Hijmans W, Sipe JD: Levels of the serum amyloid A protein (SAA) in normal persons of different age groups. Clinical and experimental immunology, 1979; 35: 96-100
44. Rienhoff HY Jr, Huang JH, Li XX, Liao WS: Molecular and cellular biology of serum amyloid A. Mol Biol Med, 1990; 7: 287-298
45. Johnson BD, Kip KE, Marroquin OC, Ridker PM, Kelsey SF, Shaw LJ, Pepine CJ, Sharaf B, Bairey Merz CN, Sopko G, Olson MB, Reis SE, National Heart L, Blood I: Serum amyloid A as a predictor of coronary artery disease and cardiovascular outcome in women: the National Heart, Lung, and Blood Institute-Sponsored Women’s Ischemia Syndrome Evaluation (WISE). Circulation, 2004; 109: 726-732
46. Fyfe AI, Rothenberg LS, DeBeer FC, Cantor RM, Rotter JI, Lusis AJ: Association between serum amyloid A proteins and coronary artery disease: evidence from two distinct arteriosclerotic processes. Circulation, 1997; 96: 2914-2919
47. Connolly M, Mullan RH, McCormick J, Matthews C, Sullivan O, Kennedy A, FitzGerald O, Poole AR, Bresnihan B, Veale DJ, Fearon U: Acute-phase serum amyloid A regulates tumor necrosis factor alpha and matrix turnover and predicts disease progression in patients with inflammatory arthritis before and after biologic therapy. Arthritis Rheum, 2012; 64: 1035-1045
48. Migita K, Koga T, Torigoshi T, Motokawa S, Maeda Y, Jiuchi Y, Izumi Y, Miyashita T, Nakamura M, Komori A, Ishibashi H: Induction of interleukin-23 p19 by serum amyloid A (SAA) in rheumatoid synoviocytes. Clin Exp Immunol, 2010; 162: 244-250
49. Connolly M, Marrelli A, Blades M, McCormick J, Maderna P, Godson C, Mullan R, FitzGerald O, Bresnihan B, Pitzalis C, Veale DJ, Fearon U: Acute serum amyloid A induces migration, angiogenesis, and inflammation in synovial cells in vitro and in a human rheumatoid arthritis/SCID mouse chimera model. J Immunol, 2010; 184: 6427-6437
50. Bjorkman L, Raynes JG, Shah C, Karlsson A, Dahlgren C, Bylund J: The proinflammatory activity of recombinant serum amyloid A is not shared by the endogenous protein in the circulation. Arthritis Rheum, 2010; 62: 1660-1665
51. Christenson K, Bjorkman L, Ahlin S, Olsson M, Sjoholm K, Karlsson A, Bylund J: Endogenous Acute Phase Serum Amyloid A Lacks Pro-Inflammatory Activity, Contrasting the Two Recombinant Variants That Activate Human Neutrophils through Different Receptors. Front Immunol, 2013; 4: 92
52. Franco AG, Sandri S, Campa A: High-density lipoprotein prevents SAA-induced production of TNF-alpha in THP-1 monocytic cells and peripheral blood mononuclear cells. Mem Inst Oswaldo Cruz, 2011; 106: 986-992