MicroRNAs in human skin ageing

Ageing Research Reviews

Volumn 17, Issue , 2014, Pages 9-15

  Mancini, Mara ^a   Lena, Anna Maria ^a   Saintigny, Gaelle ^c   Mahé, Christian ^c   Di Daniele, Nicola ^a   Melino, Gerry ^a,b   Candi, Eleonora ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b LABORATORIO DI PATOLOGIA VASCOLARE   (Italy)

^c CHANEL Parfums Beauté ^*  (France)

Author keywords

Ageing; Cellular senescence; Dermis; Epidermis; MicroRNA; P63

Indexed keywords

MICRORNA; MICRORNA 130B; MICRORNA 137; MICRORNA 138; MICRORNA 146A; MICRORNA 155; MICRORNA 17; MICRORNA 181A; MICRORNA 181B; MICRORNA 191; MICRORNA 449; MICRORNA 668; MICRORNA 92; REACTIVE OXYGEN METABOLITE; SMALL UNTRANSLATED RNA; UNCLASSIFIED DRUG;

AGING; CELL PROLIFERATION; CELLULAR STRESS RESPONSE; FIBROBLAST; GENE TARGETING; HUMAN; KERATINOCYTE; PHOTOAGING; REVIEW; SENESCENCE; SKIN PROTECTION; SKIN STRUCTURE; TELOMERE; TISSUE REGENERATION; ULTRAVIOLET RADIATION; CELL AGING; CUTANEOUS PARAMETERS; METABOLISM; PATHOLOGY; PHYSIOLOGY; SKIN;

CELL AGING; FIBROBLASTS; HUMANS; KERATINOCYTES; MICRORNAS; SKIN; SKIN AGING;

EID: 84906791268     PISSN: 15681637     EISSN: 18729649     Source Type: Journal    
DOI: 10.1016/j.arr.2014.04.003     Document Type: Review

References (65)

1. Aberdam D., Candi E., Knight R.A., Melino G. miRNAs, 'stemness' and skin. Trends Biochem. Sci. 2008, 33:583-591.
2. Amelio I., Lena A.M., Viticchiè G., Shalom-Feuerstein R., Terrinoni A., Dinsdale D., Russo G., Fortunato C., Bonanno E., Spagnoli L.G., Aberdam D., Knight R.A., Candi E., Melino G. miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration. J. Cell Biol. 2012, 199:347-363.
3. Atadja P., Wong H., Garkavtsev I., Veillette C., Riabowol K. Increased activity of p53 in senescing fibroblasts. Proc. Natl. Acad. Sci. U.S.A. 1995, 92:8348-8352.
4. Bates D.J., Liang R., Li N., Wang E. The impact of noncoding RNA on the biochemical and molecular mechanisms of aging. Biochim. Biophys. Acta 2009, 1790:970-979.
5. Benhamed M., Herbig U., Ye T., Dejean A., Bischof O. Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells. Nat. Cell Biol. 2012, 14:266-275.
6. Blanpain C., Fuchs E. Epidermal stem cells of the skin. Annu. Rev. Cell Dev. Biol. 2006, 22:339-373.
7. Callaghan T.M., Wilhelm K.P. A review of ageing and an examination of clinical methods in the assessment of ageing skin. Part I: cellular and molecular perspectives of skin ageing. Int. J. Cosmet. Sci. 2008, 30:313-322.
8. Callaghan T.M., Wilhelm K.P. A review of ageing and an examination of clinical methods in the assessment of ageing skin. Part 2: clinical perspectives and clinical methods in the evaluation of ageing skin. Int. J. Cosmet. Sci. 2008, 30:323-332.
9. Campisi J. Cancer and ageing: rival demons?. Nat. Rev. Cancer 2003, 3:339-349.
10. Candi E., Schmidt R., Melino G. The cornified envelope: a model of cell death in the skin. Nat. Rev. Mol. Cell Biol. 2005, 6:328-340.
11. Candi E., Rufini A., Terrinoni A., Dinsdale D., Ranalli M., Paradisi A., De Laurenzi V., Spagnoli L.G., Catani M.V., Ramadan S., Knight R.A., Melino G. Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice. Cell Death Differ. 2006, 13:1037-1047.
12. Candi E., Cipollone R., Rivetti di Val Cervo P., Gonfloni S., Melino G., Knight R. p63 in epithelial development. Cell. Mol. Life Sci. 2008, 65:3126-3133.
13. 2-induced cell death via modulation of p53 and JNK in cultured skin keratinocytes. J. Cell. Mol. Med. 2009, 13:3632-3643.
14. Carnero A. Markers of cellular senescence. Methods Mol. Biol. 2013, 965:63-81.
15. Chainiaux F., Magalhaes J.P., Eliaers F., Remacle J., Toussaint O. UVB-induced premature senescence of human diploid skin fibroblasts. Int. J. Biochem. Cell Biol. 2002, 34:1331-1339.
16. Chen L.H., Chiou G.Y., Chen Y.W., Li H.Y., Chiou S.H. MicroRNA and aging: a novel modulator in regulating the aging network. Ageing Res. Rev. 2010, 9(Suppl. 1):S59-S66.
17. Cloonan N., Brown M.K., Steptoe A.L., Wani S., Chan W.L., Forrest A.R., Kolle G., Gabrielli B., Grimmond S.M. The miR-17-5p microRNA is a key regulator of the G1/S phase cell cycle transition. Genome Biol. 2008, 9:R127.
18. Dimri G.P., Hara E., Campisi J. Regulation of two E2F-related genes in presenescent and senescent human fibroblasts. J. Biol. Chem. 1994, 269:16180-16186.
19. Donmez G., Guarente L. Aging and disease: connections to sirtuins. Aging Cell 2010, 9:285-290.
20. Fessing M.Y., Mardaryev A.N., Gdula M.R., Sharov A.A., Sharova T.Y., Rapisarda V., Gordon K.B., Smorodchenko A.D., Poterlowicz K., Ferone G., Kohwi Y., Missero C., Kohwi-Shigematsu T., Botchkarev V.A. p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J. Cell Biol. 2011, 194:825-839.
21. Greussing R., Hackl M., Charoentong P., Pauck A., Monteforte R., Cavinato M., Hofer E., Scheideler M., Neuhaus M., Micutkova L., Mueck C., Trajanoski Z., Grillari J., Jansen-Dürr P. Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts. BMC Genomics 2013, 14:224.
22. Guo X., Keyes W.M., Papazoglu C., Zuber J., Li W., Lowe S.W., Vogel H., Mills A.A. TAp63 induces senescence and suppresses tumorigenesis in vivo. Nat. Cell Biol. 2009, 11:1451-1457.
23. Hackl M., Brunner S., Fortschegger K., Schreiner C., Micutkova L., Mück C., Laschober G.T., Lepperdinger G., Sampson N., Berger P., Herndler-Brandstetter D., Wieser M., Kühnel H., Strasser A., Rinnerthaler M., Breitenbach M., Mildner M., Eckhart L., Tschachler E., Trost A., Bauer J.W., Papak C., Trajanoski Z., Scheideler M., Grillari-Voglauer R., Grubeck-Loebenstein B., Jansen-Dürr P., Grillari J. miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging. Aging Cell 2010, 9:291-296.
24. Haigis M.C., Sinclair D.A. Mammalian sirtuins: biological insights and disease relevance. Annu. Rev. Pathol. 2010, 5:253-295.
25. He L., Thomson J.M., Hemann M.T., Hernando-Monge E., Mu D., Goodson S., Powers S., Cordon-Cardo C., Lowe S.W., Hannon G.J., Hammond S.M. A microRNA polycistron as a potential human oncogene. Nature 2005, 435:828-833.
26. Inomata M., Tagawa H., Guo Y.M., Kameoka Y., Takahashi N., Sawada K. MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes. Blood 2009, 113:396-402.
27. Ivanovska I., Ball A.S., Diaz R.L., Magnus J.F., Kibukawa M., Schelter J.M., Kobayashi S.V., Lim L., Burchard J., Jackson A.L., Linsley P.S., Cleary M.A. MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression. Mol. Cell. Biol. 2008, 28:2167-2174.
28. Keyes W.M., Wu Y., Vogel H., Guo X., Lowe S.W., Mills A.A. p63 deficiency activates a program of cellular senescence and leads to accelerated aging. Genes Dev. 2005, 19:1986-1999.
29. Kosmadaki M.G., Gilchrest B.A. The role of telomeres in skin aging/photoaging. Micron 2004, 35:155-159.
30. Krol J., Loedige I., Filipowicz W. The widespread regulation of microRNA biogenesis, function and decay. Nat. Rev. Genet. 2010, 9:597-610.
31. Krajcovicová-Kudlácková M., Valachovicová M., Pauková V., Dusinská M. Effects of diet and age on oxidative damage products in healthy subjects. Physiol. Res. 2008, 57:647-651.
32. Kudlow B.A., Kennedy B.K., Monnat R.J. Werner and Hutchinson-Gilford progeria syndromes: mechanistic basis of human progeroid diseases. Nat. Rev. Mol. Cell Biol. 2007, 8:394-404.
33. Kulju K.S., Lehman J.M. Increased p53 protein associated with aging in human diploid fibroblasts. Exp. Cell Res. 1995, 217:336-345.
34. Lena A.M., Shalom-Feuerstein R., Rivetti di Val Cervo P., Aberdam D., Knight R.A., Melino G., Candi E. miR-203 represses 'stemness' by repressing DeltaNp63. Cell Death Differ. 2008, 15:1187-1195.
35. Lena A.M., Mancini M., Rivetti di Val Cervo P., Saintigny G., Mahé C., Melino G., Candi E. MicroRNA-191 triggers keratinocytes senescence by SATB1 and CDK6 downregulation. Biochem. Biophys. Res. Commun. 2012, 423:509-514.
36. Li W., Zhou B.R., Hua L.J., Guo Z., Luo D. Differential miRNA profile on photoaged primary human fibroblasts irradiated with ultraviolet A. Tumour Biol. 2013, 34:3491-3500.
37. Mancini M., Saintigny G., Mahé C., Annicchiarico-Petruzzelli M., Melino G., Candi E. MicroRNA-152 and -181a participate in human dermal fibroblasts senescence acting on cell adhesion and remodeling of the extra-cellular matrix. Aging 2012, 4:843-853.
38. Manni I., Artuso S., Careccia S., Rizzo M.G., Baserga R., Piaggio G., Sacchi A. The microRNA miR-92 increases proliferation of myeloid cells and by targeting p63 modulates the abundance of its isoforms. FASEB J. 2009, 23:3957-3966.
39. Makrantonaki E., Zouboulis C.C. Molecular mechanisms of skin aging: state of the art. Ann. N. Y. Acad. Sci. 2007, 1119:40-50.
40. Martinez I., Cazalla D., Almstead L.L., Steitz J.A., Di Maio D. miR-29 and miR-30 regulate B-Myb expression during cellular senescence. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:522-527.
41. Menghini R., Casagrande V., Cardellini M., Martelli E., Terrinoni A., Amati F., Vasa-Nicotera M., Ippoliti A., Novelli G., Melino G., Lauro R., Federici M. MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1. Circulation 2009, 120:1524-1532.
42. Mills A.A., Zheng B., Wang X.J., Vogel H., Roop D.R., Bradley A. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 1999, 398:708-713.
43. Mudhasani R., Zhu Z., Hutvagner G., Eischen C.M., Lyle S., Hall L.L., Lawrence J.B., Imbalzano A.N., Jones S.N. Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells. J. Cell Biol. 2008, 181:1055-1063.
44. Ning M.S., Andl T. Control by a hair's breadth: the role of microRNAs in the skin. Cell. Mol. Life Sci. 2013, 70:1149-1169.
45. Petrocca F., Visone R., Onelli M.R., Shah M.H., Nicoloso M.S., De Martino I., Iliopoulos D., Pilozzi E., Liu C.G., Negrini M., Cavazzini L., Volinia S., Alder H., Ruco L.P., Baldassarre G., Croce C.M., Vecchione A. E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. Cancer Cell 2008, 13:272-286.
46. Proksch E., Brandner J.M., Jensen J.M. The skin: an indispensable barrier. Exp. Dermatol. 2008, 17:1063-1072.
47. Quan T., Qin Z., Xu Y., He T., Kang S., Voorhees J.J., Fisher G.J. Ultraviolet irradiation induces CYR61/CCN1, a mediator of collagen homeostasis, through activation of transcription factor AP-1 in human skin fibroblasts. J. Invest. Dermatol. 2010, 130:1697-1706.
48. Rattan S.I. Theories of biological aging: genes, proteins, and free radicals. Free Radic. Res. 2006, 40:1230-1238.
49. Rivetti di Val Cervo P., Lena A.M., Nicoloso M., Rossi S., Mancini M., Zhou H., Saintigny G., Dellambra E., Odorisio T., Mahé C., Calin G.A., Candi E., Melino G. p63-microRNA feedback in keratinocyte senescence. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:1133-1138.
50. Rodier F., Campisi J., Bhaumik D. Two faces of p53: aging and tumor suppression. Nucleic Acids Res. 2007, 35:7475-7484.
51. Schmid G., Kramer M.P., Maurer M., Wandl S., Wesierska-Gadek J. Cellular and organismal ageing: role of the p53 tumor suppressor protein in the induction of transient and terminal senescence. J. Cell. Biochem. 2007, 101:1355-1369.
52. Senoo M., Pinto F., Crum C.P., McKeon F. p63 Is essential for the proliferative potential of stem cells in stratified epithelia. Cell 2007, 129:523-536.
53. Shin K.H., Pucar A., Kim R.H., Bae S.D., Chen W., Kang M.K., Park N.H. Identification of senescence-inducing microRNAs in normal human keratinocytes. Int. J. Oncol. 2011, 39:1205-1211.
54. Smith-Vikos T., Slack F.J. MicroRNAs and their roles in aging. J. Cell Sci. 2012, 125:7-17.
55. Song J., Liu P., Yang Z., Li L., Su H., Lu N., Peng Z. MiR-155 negatively regulates c-Jun expression at the post-transcriptional level in human dermal fibroblasts in vitro: implications in UVA irradiation-induced photoaging. Cell. Physiol. Biochem. 2012, 29:331-340.
56. Soriani M., Hejmadi V., Tyrrell R.M. Modulation of c-jun and c-fos transcription by UVB and UVA radiations in human dermal fibroblasts and KB cells. Photochem. Photobiol. 2000, 71:551-558.
57. Su X., Cho M.S., Gi Y.J., Ayanga B.A., Sherr C.J., Flores E.R. Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf. EMBO J. 2009, 28:1904-1915.
58. Yaar M., Gilchrest B.A. Photoageing: mechanism, prevention and therapy. Br. J. Dermatol. 2007, 157:874-887.
59. Yan H.L., Xue G., Mei Q., Wang Y.Z., Ding F.X., Liu M.F., Lu M.H., Tang Y., Yu H.Y., Sun S.H. Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis. EMBO J. 2009, 28:2719-2732.
60. Yang A., Schweitzer R., Sun D., Kaghad M., Walker N., Bronson R.T., Tabin C., Sharpe A., Caput D., Crum C., McKeon F. p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 1999, 398:714-718.
61. Yi R., Fuchs E. MicroRNA-mediated control in the skin. Cell Death Differ. 2010, 17:229-235.
62. Zouboulis C.C., Chen W.C., Thornton M.J., Qin K., Rosenfield R. Sexual hormones in human skin. Horm. Metab. Res. 2007, 39:85-95.
63. Zouboulis C.C., Makrantonaki E. Clinical aspects and molecular diagnostics of skin aging. Clin. Dermatol. 2011, 29:3-14.
64. Zhou M.J., Zheng L., Guo L., Liu W.L., Lv C., Jiang L.H., Ou C.S., Ding Z.H. Differential responses to UVB irradiation in human keratinocytes and epidermoid carcinoma cells. Biomed. Environ. Sci. 2012, 25:583-589.
65. Zhou B.R., Guo X.F., Zhang J.A., Xu Y., Li W., Wu D., Yin Z.Q., Permatasari F., Luo D. Elevated miR-34c-5p mediates dermal fibroblast senescence by ultraviolet irradiation. Int. J. Biol. Sci. 2013, 9:743-752.