Differential miRNA profile on photoaged primary human fibroblasts irradiated with ultraviolet A

Tumor Biology

Volumn 34, Issue 6, 2013, Pages 3491-3500

  Li, Wei ^a   Zhou, Bing Rong ^a   Hua, Li Juan ^a   Guo, Ze ^a   Luo, Dan ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Fibroblasts; miR 146a; Photoaging; Smad4; UVA

Indexed keywords

MICRORNA; MICRORNA 146A; SMAD4 PROTEIN;

ARTICLE; BIOINFORMATICS; CELL AGING; CELL PROLIFERATION; CELLULAR STRESS RESPONSE; CUTANEOUS PARAMETERS; DOWN REGULATION; FIBROBLAST; GENE CONTROL; GENE EXPRESSION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LUCIFERASE ASSAY; MALE; MICROARRAY ANALYSIS; NORMAL HUMAN; PHOTOAGING; PRIMARY CULTURE; PRIORITY JOURNAL; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; RADIATION RESPONSE; REAL TIME POLYMERASE CHAIN REACTION; ULTRAVIOLET A RADIATION; WESTERN BLOTTING;

EID: 84891481486     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-013-0927-4     Document Type: Article

References (43)

1. Fisher GJ et al. Mechanisms of photoaging and chronological skin aging. Arch Dermatol. 2002;138(11):1462-70.
2. Marrot L, Meunier JR. Skin DNA photodamage and its biological consequences. J Am Acad Dermatol. 2008;58(5 Suppl 2):S139-48.
3. Timares L, Katiyar SK, Elmets CA. DNA damage, apoptosis and langerhans cells - activators of UV-induced immune tolerance. Photochem Photobiol. 2008;84(2):422-36.
4. Krutmann J. The role of UVA rays in skin aging. Eur J Dermatol. 2001;11(2):170-1.
5. Berneburg M, Plettenberg H, Krutmann J. Photoaging of human skin. Photodermatol Photoimmunol Photomed. 2000;16(6):239-44.
6. Rijken F et al. Pathophysiology of photoaging of human skin: focus on neutrophils. Photochem Photobiol Sci. 2006;5(2):184-9.
7. Wang B. Photoaging: a review of current concepts of pathogenesis. J Cutan Med Surg. 2011;15 Suppl 1:S374-7.
8. Heck DE et al. Solar ultraviolet radiation as a trigger of cell signal transduction. Toxicol Appl Pharmacol. 2004;195(3):288-97.
9. Guo Z et al. MiR-23a regulates DNA damage repair and apoptosis in UVB-irradiated HaCaT cells. J Dermatol Sci. 2013;69(1):68-76.
10. Lu C, Ding ZH, Zhou MJ. [Mechanisms of ultraviolet B irradiation-induced injuries in 16HBE cells]. Nan Fang Yi Ke Da Xue Xue Bao. 2011;31(1):57-60.
11. Guo L et al. Differential expression profiles of microRNAs in NIH3T3 cells in response to UVB irradiation. Photochem Photobiol. 2009;85(3):765-73.
12. Pothof J et al. MicroRNA responses and stress granule formation modulate the DNA damage response. Cell Cycle. 2009;8(21):3462-8.
13. Pothof J et al. MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response. EMBO J. 2009;28(14):2090-9.
14. Wei L, Wu D, Lijuan H, Bingrong Z, Ze G, Dan L. UVB suppresses PTEN expression by upregulating miR-141 in HaCaT cells. J Biomed Res. 2011;25(2):135-40.
15. Lin SL et al. Loss of mir-146a function in hormone-refractory prostate cancer. RNA. 2008;14(3):417-24.
16. Boldin MP et al. miR-146a is a significant brake on autoimmunity, myeloproliferation, and cancer in mice. J Exp Med. 2011;208(6):1189-201.
17. Li Y et al. miR-146a suppresses invasion of pancreatic cancer cells. Cancer Res. 2010;70(4):1486-95.
18. Hurst DR et al. Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis. Cancer Res. 2009;69(4):1279-83.
19. Chatzikyriakidou A et al. The role of microRNA-146a (miR-146a) and its target IL-1R-associated kinase (IRAK1) in psoriatic arthritis susceptibility. Scand J Immunol. 2010;71(5):382-5.
20. Rom S et al. CCL8/MCP-2 is a target for mir-146a in HIV-1-infected human microglial cells. FASEB J. 2010;24(7):2292-300.
21. Zhong H et al. Targeting Smad4 links microRNA-146a to the TGF-beta pathway during retinoid acid induction in acute promyelocytic leukemia cell line. Int J Hematol. 2010;92(1):129-35.
22. Xiao B et al. Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis. Oncol Rep. 2012;27(2):559-66.
23. Curtale G et al. An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes. Blood. 2010;115(2):265-73.
24. Hou J et al. MicroRNA-146a feedback inhibits RIG-I-dependent Type I IFN production in macrophages by targeting TRAF6, IRAK1, and IRAK2. J Immunol. 2009;183(3):2150-8.
25. Yamaue H et al. Chemosensitivity testing of fresh human gastric cancer with highly purified tumour cells using the MTT assay. Br J Cancer. 1992;66(5):794-9.
26. Young AR. Cumulative effects of ultraviolet radiation on the skin: cancer and photoaging. Semin Dermatol. 1990;9(1):25-31.
27. Liu Z et al. MicroRNA-146a modulates TGF-beta1-induced phenotypic differentiation in human dermal fibroblasts by targeting SMAD4. Arch Dermatol Res. 2012;304(3):195-202.
28. Scharffetter-Kochanek K et al. Photoaging of the skin from phenotype to mechanisms. Exp Gerontol. 2000;35(3):307-16.
29. Krutmann J. Ultraviolet A radiation-induced biological effects in human skin: relevance for photoaging and photodermatosis. J Dermatol Sci. 2000;23 Suppl 1:S22-6.
30. Gasparro FP. Sunscreens, skin photobiology, and skin cancer: the need for UVA protection and evaluation of efficacy. Environ Health Perspect. 2000;108 Suppl 1:71-8.
31. Zhou BR et al. Characterization of the miRNA profile in UVB-irradiated normal human keratinocytes. Exp Dermatol. 2012;21(4):317-9.
32. Hiramoto K et al. Long-term ultraviolet A irradiation of the eye induces photoaging of the skin in mice. Arch Dermatol Res. 2012;304(1):39-45.
33. Song J et al. MiR-155 negatively regulates c-Jun expression at the post-transcriptional level in human dermal fibroblasts in vitro: implications in UVA irradiation-induced photoaging. Cell Physiol Biochem. 2012;29(3-4):331-40.
34. Zhang X et al. The ATM kinase induces microRNA biogenesis in the DNA damage response. Mol Cell. 2011;41(4):371-83.
35. Suzuki HI, Miyazono K. Dynamics of microRNA biogenesis: crosstalk between p53 network and microRNA processing pathway. J Mol Med (Berl). 2010;88(11):1085-94.
36. Wakasugi M et al. DDB accumulates at DNA damage sites immediately after UV irradiation and directly stimulates nucleotide excision repair. J Biol Chem. 2002;277(3):1637-40.
37. van Rooij E et al. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science. 2007;316(5824):575-9.
38. Leung AK, Sharp PA. MicroRNA functions in stress responses. Mol Cell. 2010;40(2):205-15.
39. Iorio MV, Croce CM. MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review. EMBO Mol Med. 2012;4(3):143-59.
40. Filipowicz W, Bhattacharyya SN, Sonenberg N. Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet. 2008;9(2):102-14.
41. Yasutome M, Gunn J, Korc M. Restoration of Smad4 in BxPC3 pancreatic cancer cells attenuates proliferation without altering angiogenesis. Clin Exp Metastasis. 2005;22(6):461-73.
42. Giehl K et al. TGFbeta1 represses proliferation of pancreatic carcinoma cells which correlates with Smad4-independent inhibition of ERK activation. Oncogene. 2000;19(39):4531-41.
43. Azar R et al. 4E-BP1 is a target of Smad4 essential for TGFbeta-mediated inhibition of cell proliferation. EMBO J. 2009;28(22):3514-22.