Analysis of diazofluorene DNA binding and damaging activity: DNA cleavage by a synthetic monomeric diazofluorene

Angewandte Chemie - International Edition

Volumn 53, Issue 35, 2014, Pages 9325-9328

  Woo, Christina M ^a   Ranjan, Nihar ^b   Arya, Dev P ^b   Herzon, Seth B ^a  

^a YALE UNIVERSITY   (United States)

^b CLEMSON UNIVERSITY   (United States)

Author keywords

cancer; DNA cleavage; DNA damage; natural products

Indexed keywords

FUNCTIONAL GROUPS; KETONES; TISSUE CULTURE; TRANSLATION (LANGUAGES);

CANCER; CHAIN ISOMERIZATION; DNA BINDING AND CLEAVAGES; DNA CLEAVAGE; DNA DAMAGES; ITS APPLICATIONS; NATURAL PRODUCTS; SKELETON STRUCTURE;

DNA;

CALF THYMUS DNA; DIAZONIUM COMPOUND; DNA; FLUORENE DERIVATIVE;

ANIMAL; BINDING SITE; BOVINE; CHEMICAL STRUCTURE; CHEMISTRY; DNA CLEAVAGE; DNA DAMAGE; DOSE RESPONSE; DRUG EFFECTS; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; BINDING SITES; CATTLE; DIAZONIUM COMPOUNDS; DNA; DNA CLEAVAGE; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORENES; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84906789106     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201404137     Document Type: Article

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