Studies on the mechanism of action of prekinamycin, a member of the diazoparaquinone family of natural products: Evidence for both sp2 radical and orthoquinonemethide intermediates

Journal of the American Chemical Society

Volumn 128, Issue 38, 2006, Pages 12562-12573

  Feldman, Ken S ^a   Eastman, Kyle J ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC COMPOUNDS; ETHERS; REACTION KINETICS; REDUCTION;

ACTIVATION CHEMISTRY; AROMATIC SOLVENTS; ELECTROPHILES;

ANTIBIOTICS;

ANTIBIOTIC AGENT; AROMATIC COMPOUND; BENZYL DERIVATIVE; CYCLOPENTANE DERIVATIVE; DIAZOPARAQUINONE DERIVATIVE; FL 120'; FL 120A; FL 120B; FL 120B'; FL 120C; FL 120C'; FL 120D'; ISOPREKINAMYCIN; KETOANHYDROKINAMYCIN; KINAMYCIN; KINAMYCIN DERIVATIVE; KINAMYCIN E; KINAMYCIN F; KINAMYCIN G; KINAMYCIN H; KINAMYCIN I; KINAMYCIN J; LAGUNAMYCIN; NATURAL PRODUCT; PREKINAMYCIN; QUINONE DERIVATIVE; SOLVENT; SULFIDE; THIOL DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZINOSTATIN DERIVATIVE;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; DRUG ACTIVITY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; STRUCTURE ANALYSIS;

ANTI-INFECTIVE AGENTS; QUINONES;

EID: 33749174128     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0642616     Document Type: Article

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