Mimicking the biological activity of diazobenzo[b]fluorene natural products with electronically tuned diazofluorene analogs

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 19, 2006, Pages 5148-5151

  Zeng, Wei ^a   Eric Ballard, T ^a   Tkachenko, Alexander G ^a   Burns, Virginia A ^a   Feldheim, Daniel L ^a   Melander, Christian ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Antiproliferative activity; Diazofluorenes; DNA cleavage; Kinamycins; Lomaiviticins

Indexed keywords

1 AMINODIAZOFLUORENE; 1 CHLORODIAZOFLUORENE; 1 METHOXYDIAZOFLUORENE; 1 NITRODIAZOFLUORENE; 1,4 DIMETHOXYDIAZOFLUORENE; 4 AMINODIAZOFLUORENE; 4 CHLORODIAZOFLUORENE; 4 METHOXYDIAZOFLUORENE; 4 NITRODIAZOFLUORENE; ANTINEOPLASTIC AGENT; DIAZOBENZO[B]FLUORENE; DIAZOFLUORENE DERIVATIVE; DIAZOQUINOFLUORENE; FLUORENE DERIVATIVE; KINAMYCIN; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL ACTIVITY; CELL PROLIFERATION; CONTROLLED STUDY; DNA CLEAVAGE; DRUG SYNTHESIS; FEMALE; HELA CELL; HUMAN; HUMAN CELL;

ANIMALS; ANTINEOPLASTIC AGENTS; CARBAZOLES; CELL PROLIFERATION; DNA DAMAGE; FLUORENES; HELA CELLS; HUMANS; MOLECULAR MIMICRY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33747358059     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.07.024     Document Type: Article

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