Protective effects of phosphodiesterase-1 (PDE1) and ATP sensitive potassium (KATP) channel modulators against 3-nitropropionic acid induced behavioral and biochemical toxicities in experimental Huntingtons disease

European Journal of Pharmacology

Volumn 732, Issue 1, 2014, Pages 111-122

  Gupta, Surbhi ^a   Sharma, Bhupesh ^b,c  

^a Neuropharmacology Lab Department of Pharmacology School of Pharmacy   (India)

^b BHARAT INSTITUTE OF TECHNOLOGY   (India)

^c Dilshad Garden   (India)

Author keywords

3 Nitropropionic acid; Acetylcholinesterase; Mitochondrial enzyme complexes; Myeloperoxidase; Nicorandil; Vinpocetine

Indexed keywords

3 NITROPROPIONIC ACID; ACETYLCHOLINESTERASE; ADENOSINE TRIPHOSPHATASE; CATALASE; CYTOCHROME C OXIDASE; GLUTATHIONE; MALONALDEHYDE; NICORANDIL; PHOSPHODIESTERASE I; POTASSIUM CHANNEL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SUCCINATE DEHYDROGENASE; SUPEROXIDE DISMUTASE; TETRABENAZINE; VINPOCETINE; 3-NITROPROPIONIC ACID; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; NITRO DERIVATIVE; PHOSPHODIESTERASE INHIBITOR; PROPIONIC ACID DERIVATIVE; VINCA ALKALOID;

ANIMAL EXPERIMENT; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; CORPUS STRIATUM; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ELEVATED PLUS MAZE TEST; ENZYME ACTIVITY; GRIP STRENGTH; HUNTINGTON CHOREA; INFLAMMATION; LEARNING; LIPID PEROXIDATION; LOCOMOTION; MEMORY; MORRIS WATER MAZE TEST; NEUROPROTECTION; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; ROTAROD TEST; WEIGHT REDUCTION; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; DRUG EFFECTS; ENZYMOLOGY; FEMALE; HUNTINGTON DISEASE; MALE; MAZE TEST; METABOLISM; MOTOR ACTIVITY; NEOSTRIATUM; PSYCHOLOGY; TOXICITY; WISTAR RAT;

ANIMALS; FEMALE; HUNTINGTON DISEASE; KATP CHANNELS; MALE; MAZE LEARNING; MOTOR ACTIVITY; NEOSTRIATUM; NICORANDIL; NITRO COMPOUNDS; PHOSPHODIESTERASE I; PHOSPHODIESTERASE INHIBITORS; PROPIONATES; RATS; RATS, WISTAR; VINCA ALKALOIDS;

EID: 84906570507     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.03.032     Document Type: Article

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