Nicorandil inhibits inflammasome activation and toll-like receptor-4 signal transduction to protect against oxygen-glucose deprivation-induced inflammation in BV-2 cells

CNS Neuroscience and Therapeutics

Volumn 20, Issue 2, 2014, Pages 147-153

  Zhao, An Peng ^a   Dong, Yin Feng ^b   Liu, Wei ^a   Gu, Jun ^a   Sun, Xiu Lan ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

ATP sensitive potassium channel; Inflammasome; Neuroinflammation; Nicorandil; Oxygen glucose deprivation

Indexed keywords

GLUCOSE; INFLAMMASOME; INTERLEUKIN 1BETA; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.1; NICORANDIL; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; OXYGEN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL STRAIN; CELL STRAIN BV 2; CHANNEL GATING; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DEPLETION; DOWN REGULATION; DRUG MECHANISM; MICROGLIA; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OXYGEN GLUCOSE DEPRIVATION; PROTEIN INDUCTION; SIGNAL TRANSDUCTION;

ATP-SENSITIVE POTASSIUM CHANNEL; INFLAMMASOME; NEUROINFLAMMATION; NICORANDIL; OXYGEN-GLUCOSE DEPRIVATION;

ANIMALS; ANOXIA; CARRIER PROTEINS; CASPASE 1; CELL LINE, TRANSFORMED; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GLUCOSE; I-KAPPA B KINASE; INFLAMMATION; INTERLEUKIN-1BETA; KATP CHANNELS; L-LACTATE DEHYDROGENASE; MICE; NICORANDIL; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA; VITAMIN B COMPLEX;

EID: 84892489801     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/cns.12178     Document Type: Article

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