Role of oxidative stress, inflammation, nitric oxide and transforming growth factor-beta in the protective effect of diosgenin in monocrotaline-induced pulmonary hypertension in rats

European Journal of Pharmacology

Volumn 740, Issue , 2014, Pages 379-387

  Ahmed, Lamiaa A ^a   Obaid, Al Arqam Z ^a   Zaki, Hala F ^a   Agha, Azza M ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

Diosgenin; Monocrotaline; Nitric oxide; Oxidative stress; Pulmonary hypertension

Indexed keywords

CASPASE 3; DIOSGENIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE; INDUCIBLE NITRIC OXIDE SYNTHASE; MONOCROTALINE; NITRIC OXIDE; NOS2 PROTEIN, RAT; NOS3 PROTEIN, RAT; PEROXIDASE; PROTECTIVE AGENT; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; HEART VENTRICLE; HYPERTENSION, PULMONARY; INFLAMMATION; LUNG; MALE; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; PULMONARY ARTERY; WISTAR RAT;

ANIMALS; CASPASE 3; DIOSGENIN; GLUTATHIONE; HEART VENTRICLES; HYPERTENSION, PULMONARY; INFLAMMATION; LUNG; MALE; MONOCROTALINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PEROXIDASE; PROTECTIVE AGENTS; PULMONARY ARTERY; RATS, WISTAR; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84906569212     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.07.026     Document Type: Article

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