High density and ligand affinity confer ultrasensitive signal detection by a guanylyl cyclase chemoreceptor

Journal of Cell Biology

Volumn 206, Issue 4, 2014, Pages 541-557

  Pichlo, Magdalena ^a,b   Bungert Plümke, Stefanie ^b,c   Weyand, Ingo ^b,c   Seifert, Reinhard ^a,b   Bönigk, Wolfgang ^a   Strünker, Timo ^a,b   Kashikar, Nachiket Dilip ^a,b,d   Goodwin, Normann ^a,b,e   Müller, Astrid ^a   Pelzer, Patric ^b,i   Van, Qui ^f   Enderlein, Jörg ^f   Klemm, Clementine ^g   Krause, Eberhard ^g   Trötschel, Christian ^h   Poetsch, Ansgar ^h   Kremmer, Elisabeth ^j   Kaupp, U Benjamin ^a,b  

^a CENTER OF ADVANCED EUROPEAN STUDIES AND RESEARCH CAESAR   (Germany)

^b MARINE BIOLOGICAL LABORATORY   (United States)

^c FORSCHUNGSZENTRUM JÜLICH   (Germany)

^d UNIVERSITY OF SUSSEX   (United Kingdom)

^e BABRAHAM INSTITUTE   (United Kingdom)

^f UNIVERSITY OF GÖTTINGEN   (Germany)

^g LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^h RUHR UNIVERSITY BOCHUM   (Germany)

ⁱ UNIVERSITY OF HEIDELBERG   (Germany)

^j INSTITUTE OF EPIDEMIOLOGY   (Germany)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CALYCULIN A; CHEMOATTRACTANT; GUANYLATE CYCLASE; GUANYLYL CYCLASE RECEPTOR; LIGAND; OKADAIC ACID; RECEPTOR; SANGUINARINE; UNCLASSIFIED DRUG;

ALKALINIZATION; AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; ANIMAL CELL; ANTENNA (ORGAN); ARBACIA PUNCTULATA; ARTICLE; BINDING AFFINITY; CELL PH; CELL SURFACE; CHEMORECEPTOR; CONTROLLED STUDY; DEGLYCOSYLATION; ELECTROPHORETIC MOBILITY; ENZYME ACTIVITY; EUKARYOTIC FLAGELLUM; HEK293 CELL LINE; HUMAN; HUMAN CELL; HYPERPOLARIZATION; IMMUNOHISTOCHEMISTRY; LIGAND BINDING; MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; QUANTITATIVE ANALYSIS; RECEPTOR BINDING; RECEPTOR DENSITY; RECEPTOR OCCUPANCY; SENSORY SYSTEM; SIGNAL DETECTION; SPERM; STOICHIOMETRY; WESTERN BLOTTING;

ANIMALS; ARBACIA; CHEMORECEPTOR CELLS; CHEMOTACTIC FACTORS; CYCLIC GMP; GUANYLATE CYCLASE; HEK293 CELLS; HUMANS; MALE; PHOSPHORYLATION; PROTEIN BINDING; RECEPTORS, GUANYLATE CYCLASE-COUPLED; SIGNAL TRANSDUCTION; SPERMATOZOA;

EID: 84906515139     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201402027     Document Type: Article

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