Mass spectrometric identification of phosphorylation sites in guanylyl cyclase A and B

Biochemistry

Volumn 49, Issue 47, 2010, Pages 10137-10145

  Yoder, Andrea R ^a   Stone, Matthew D ^a   Griffin, Timothy J ^a   Potter, Lincoln R ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLASE ACTIVITY; CYCLASES; GUANYLYL CYCLASE; HEK293 CELLS; HUMAN HOMOLOGUE; MASS SPECTROMETRIC IDENTIFICATION; NATRIURETIC PEPTIDES; PHOSPHORYLATION SITES; TRANSMEMBRANES; TRYPTIC DIGESTS; WILD TYPES;

AMINO ACIDS; LIGANDS; MASS SPECTROMETRY;

PHOSPHORYLATION;

ALANINE; GLUTAMIC ACID; NATRIURETIC PEPTIDE RECEPTOR A; NATRIURETIC PEPTIDE RECEPTOR B;

ARTICLE; DESENSITIZATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; RODENT; SUBSTITUTION REACTION;

AMINO ACID SEQUENCE; ANIMALS; HEK293 CELLS; HUMANS; PHOSPHORYLATION; RATS; RECEPTORS, ATRIAL NATRIURETIC FACTOR; TANDEM MASS SPECTROMETRY;

RATTUS;

EID: 78649494041     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi101700e     Document Type: Article

References (26)

1. Potter, L. R., Yoder, A. R., Flora, D. R., Antos, L. K., and Dickey, D. M. (2009) Natriuretic peptides: their structures, receptors, physiologic functions and therapeutic applications Handb. Exp. Pharmacol., 341-366
2. Potter, L. R. (2009) Guanylyl cyclases, in Handbook of Cell Signaling (Bradshaw, R. A. and Dennis, E. A., Eds.) Academic Press, Oxford.
3. Potter, L. R. (1998) Phosphorylation-dependent regulation of the guanylyl cyclase-linked natriuretic peptide receptor B: dephosphorylation is a mechanism of desensitization Biochemistry 37, 2422-2429
4. Joubert, S., Labrecque, J., and De Lean, A. (2001) Reduced activity of the NPR-A kinase triggers dephosphorylation and homologous desensitization of the receptor Biochemistry 40, 11096-11105
5. Koller, K. J., Lipari, M. T., and Goeddel, D. V. (1993) Proper glycosylation and phosphorylation of the type A natriuretic peptide receptor are required for hormone-stimulated guanylyl cyclase activity J. Biol. Chem. 268, 5997-6003
6. Potter, L. R. and Garbers, D. L. (1992) Dephosphorylation of the guanylyl cyclase-A receptor causes desensitization J. Biol. Chem. 267, 14531-14534
7. Potter, L. R. and Hunter, T. (1998) Phosphorylation of the kinase homology domain is essential for activation of the A-type natriuretic peptide receptor Mol. Cell. Biol. 18, 2164-2172
8. Potter, L. R. and Hunter, T. (1998) Identification and characterization of the major phosphorylation sites of the B-type natriuretic peptide receptor J. Biol. Chem. 273, 15533-15539
9. Potter, L. R. and Hunter, T. (1999) Identification and characterization of the phosphorylation sites of the guanylyl cyclase-linked natriuretic peptide receptors A and B Methods 19, 506-520
10. Potter, L. R. and Hunter, T. (1999) A constitutively " phosphorylated" guanylyl cyclase-linked atrial natriuretic peptide receptor mutant is resistant to desensitization Mol. Biol. Cell 10, 1811-1820
11. Ramarao, C. S. and Garbers, D. L. (1988) Purification and properties of the phosphorylated form of guanylate cyclase J. Biol. Chem. 263, 1524-1529
12. Dickey, D. M., Burnett, J. C., Jr., and Potter, L. R. (2008) Novel bifunctional natriuretic peptides as potential therapeutics J. Biol. Chem. 283, 35003-35009
13. Dickey, D. M., Yoder, A. R., and Potter, L. R. (2009) A familial mutation renders atrial natriuretic peptide resistant to proteolytic degradation J. Biol. Chem. 284, 19196-19202
14. Bryan, P. M. and Potter, L. R. (2002) The atrial natriuretic peptide receptor (NPR-A/GC-A) is dephosphorylated by distinct microcystin-sensitive and magnesium-dependent protein phosphatases J. Biol. Chem. 277, 16041-16047
15. Abbey, S. E. and Potter, L. R. (2002) Vasopressin-dependent inhibition of the C-type natriuretic peptide receptor, NPR-B/GC-B, requires elevated intracellular calcium concentrations J. Biol. Chem. 277, 42423-42430
16. Shevchenko, A., Tomas, H., Havlis, J., Olsen, J. V., and Mann, M. (2006) In-gel digestion for mass spectrometric characterization of proteins and proteomes Nat. Protoc. 1, 2856-2860
17. Ficarro, S. B., Salomon, A. R., Brill, L. M., Mason, D. E., Stettler-Gill, M., Brock, A., and Peters, E. C. (2005) Automated immobilized metal affinity chromatography/nano-liquid chromatography/electrospray ionization mass spectrometry platform for profiling protein phosphorylation sites Rapid Commun. Mass Spectrom. 19, 57-71
18. Villen, J. and Gygi, S. P. (2008) The SCX/IMAC enrichment approach for global phosphorylation analysis by mass spectrometry Nat. Protoc. 3, 1630-1638
19. Rappsilber, J., Mann, M., and Ishihama, Y. (2007) Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips Nat. Protoc. 2, 1896-1906
20. Bandhakavi, S., Stone, M. D., Onsongo, G., Van Riper, S. K., and Griffin, T. J. (2009) A dynamic range compression and three-dimensional peptide fractionation analysis platform expands proteome coverage and the diagnostic potential of whole saliva J. Proteome Res. 8, 5590-5600
21. Antos, L. K., Abbey-Hosch, S. E., Flora, D. R., and Potter, L. R. (2005) ATP-independent activation of natriuretic peptide receptors J. Biol. Chem. 280, 26928-26932
22. Bryan, P. M. and Potter, L. R. (2002) The atrial natriuretic peptide receptor (NPR-A/GC-A) is dephosphorylated by distinct microcystin-sensitive and magnesium-dependent protein phosphatases J. Biol. Chem. 277, 16041-16047
23. Abbey-Hosch, S. E., Smirnov, D., and Potter, L. R. (2005) Differential regulation of NPR-B/GC-B by protein kinase C and calcium Biochem. Pharmacol. 70, 686-694
24. Potthast, R., Abbey-Hosch, S. E., Antos, L. K., Marchant, J. S., Kuhn, M., and Potter, L. R. (2004) Calcium-dependent dephosphorylation mediates the hyperosmotic and lysophosphatidic acid-dependent inhibition of natriuretic peptide receptor-B/guanylyl cyclase-B J. Biol. Chem. 279, 48513-48519
25. Schroter, J., Zahedi, R. P., Hartmann, M., Gassner, B., Gazinski, A., Waschke, J., Sickmann, A., and Kuhn, M. (2010) Homologous desensitization of guanylyl cyclase A, the receptor for atrial natriuretic peptide, is associated with a complex phosphorylation pattern FEBS J. 277, 2440-2453
26. Bereta, G., Wang, B., Kiser, P. D., Baehr, W., Jang, G. F., and Palczewski, K. (2010) A functional kinase homology domain is essential for the activity of photoreceptor guanylate cyclase 1 J. Biol. Chem. 285, 1899-1908