Variability in the time course of single photon responses from toad rods: Termination of rhodopsin's activity

Neuron

Volumn 23, Issue 2, 1999, Pages 337-351

  Whitlock, G G ^a   Lamb, T D ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; RHODOPSIN;

ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; EVOKED RESPONSE; FEEDBACK SYSTEM; LIGHT EXPOSURE; NONHUMAN; PHOTOTRANSDUCTION; PRIORITY JOURNAL; RETINA ROD; STIMULUS RESPONSE; STOCHASTIC MODEL; TIME; TOAD;

EID: 0033152452     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)80784-9     Document Type: Article

References (29)

1. Baylor, D.A. (1996). How photons start vision. Proc. Natl. Acad. Sci. USA 93, 560-565.
2. Baylor, D.A., Lamb, T.D., and Yau, K.-W. (1979). Responses of retinal rods to single photons. J. Physiol. 288, 613-634.
3. Baylor, D.A., Matthews, G., and Yau, K.-W. (1980). Two componentsof electrical dark noise in toad retinal rod outer segments. J. Physiol. 309, 591-621.
4. Baylor, D.A., Nunn, B.J., and Schnapf, J.L. (1984). The photocurrent, noise and spectral sensitivity of rods of the monkey Macaca fascicularis. J. Physiol. 357, 575-607.
5. Fowles, C., Sharma, R., and Akhtar, M. (1988). Mechanistic studiesof the phosphorylation of photoexcited rhodopsin. FEBS Lett. 238, 56-60.
6. Gorczyca, W.A., Gray-Keller, M.P., Detwiler, P.B., and Palczewski, K. (1994). Purification and physiological identification of a guanylate cyclase activating protein from retinal rods. Proc. Natl. Acad. Sci.USA 91, 4014-4018.
7. He, W., Cowan, C.W., and Wensel, T.G. (1998). RGS9, a GTPase accelerator for phototransduction. Neuron 20, 95-102.
8. Kawamura, S. (1993). Rhodopsin phosphorylation as a mechanism of cyclic GMP phosphodiesterase regulation by S-modulin. Nature 362, 855-857.
9. Klenchin, V.A., Calvert, P.D., and Bownds, M.D. (1995). Inhibition of rhodopsin kinase by recoverin. Further evidence for a negative feedback system in phototransduction. J. Biol. Chem. 270, 16147-16152.
10. Lamb, T.D., and Pugh, E.N., Jr. (1992). A quantitative account of the activation steps involved in phototransduction in amphibian photoreceptors. J. Physiol. 449, 719-758.
11. Lamb, T.D., McNaughton, P.A., and Yau, K.-W. (1981). Spatial spread of activation and background desensitization in toad rod outer segments. J. Physiol. 319, 463-496.
12. Lamb, T.D., Matthews, H.R., and Torre, V. (1986). Incorporation of calcium buffers into salamander retinal rods: A rejection of the calcium hypothesis of phototransduction. J. Physiol. 372, 315-349.
13. Leibrock, C.S., Reuter, T., and Lamb, T.D. (1994). Dark adaptation of toad rod photoreceptors following small bleaches. Vision Res. 34, 2787-2800.
14. Makino, E.R., Handy, J.W., Li, T.S., and Arshavsky, V.Y. (1999). The GTPase activating factor for transducin in rod photoreceptors is the complex between RGS9 and type 5 G protein β subunit. Proc. Natl. Acad. Sci. USA 96, 1947-1952.
15. Matthews, H.R. (1991). Incorporation of calcium chelator into guinea-pig rods shows that calcium mediates mammalian photoreceptor light adaptation. J. Physiol. 436, 93-105.
16. Matthews, H.R., Murphy, R.L.W., Fain, G.L., and Lamb, T.D. (1988). Photoreceptor light adaptation is mediated by cytoplasmic calcium concentration. Nature 334, 67-69.
17. Miller, J.L., Fox, D.A., and Litman, B.J. (1986). Amplification of phosphodiesterase activation is greatly reduced by rhodopsin phosphorylation. Biochemistry 25, 4983-4988.
18. Nakatani, K., and Yau, K.-W. (1988). Calcium and light adaptation in retinal rods and cones. Nature 334, 69-71.
19. Nikonov, S., Engheta, N., and Pugh, E.N., Jr. (1998). Kinetics of recovery of the dark-adapted salamander rod photoresponse. J. Gen. Physiol. 111, 7-37.
20. Pulvermüller, A., Palczewski, K., and Hofmann, K.P. (1993). Interaction between photoactivated rhodopsin and its kinase: Stability and kinetics of complex formation. Biochemistry 32, 14082-14088.
21. Rieke, F., and Baylor, D.A. (1996). Molecular origin of continuous dark noise in rod photoreceptors. Biophys. J. 71, 2553-2572.
22. Rieke, F., and Baylor, D.A. (1998). Origin of reproducibility in the responses of retinal rods to single photons. Biophys. J. 75, 1836-1857.
23. Schnapf, J.L. (1983). Dependence of the single photon response on longitudinal position of absorption in toad rod outer segments. J. Physiol. 343, 147-159.
24. Schneeweis, D.M., and Schnapf, J.L. (1995). Photovoltage of rods and cones in the macaque retina. Science 268, 1053-1056.
25. Tanaka, T., Ames, J.B., Harvey, T.S., Stryer, L., and Ikura, M. (1995). Sequestration of the membrane-targeting myristoyl group of recoverin in the calcium-free state. Nature 376, 444-447.
26. Torre, V., Matthews, H.R., and Lamb, T.D. (1986). Role of calcium in regulating the cyclic nucleotide cascade of phototransduction in retinal rods. Proc. Natl. Acad. Sci. USA 83, 7109-7113.
27. Whitlock, G.G. (1998). Single-photon Responses of Toad Rod photoreceptors. PhD thesis, University of Cambridge, Cambridge, United Kingdom.
28. Wilden, U., Hall, S.W., and Kühn, H. (1986). Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segment. Proc. Natl. Acad. Sci. USA 83, 1174-1178.
29. Yau, K.-W., and Nakatani, K. (1985). Light-induced reduction of cytoplasmic free calcium in retinal rod outer segment. Nature 313, 579-582.