Cyanidin-3-glucoside inhibits UVB-induced oxidative damage and inflammation by regulating MAP kinase and NF-κB signaling pathways in SKH-1 hairless mice skin

Toxicology and Applied Pharmacology

Volumn 280, Issue 1, 2014, Pages 127-137

  Pratheeshkumar, Poyil ^a   Son, Young Ok ^a   Wang, Xin ^a   Divya, Sasidharan Padmaja ^a   Joseph, Binoy ^b   Hitron, John Andrew ^a   Wang, Lei ^a   Kim, Donghern ^a   Yin, Yuanqin ^a,c   Roy, Ram Vinod ^a   Lu, Jian ^a,d   Zhang, Zhuo ^a   Wang, Yitao ^e   Shi, Xianglin ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c CHINA MEDICAL UNIVERSITY   (China)

^d JIANGSU UNIVERSITY   (China)

^e University of Macau   (Macao)

Author keywords

COX 2; Cyanidin 3 glucoside; Inflammation; NF B; Ultraviolet radiation

Indexed keywords

CYANIDIN 3 GLUCOSIDE; CYCLIN D1; CYCLOOXYGENASE 2; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOPEROXIDASE; PROSTAGLANDIN E2; PYRIMIDINE DIMER; SKIN PROTECTIVE AGENT; STRESS ACTIVATED PROTEIN KINASE 1; TUMOR NECROSIS FACTOR ALPHA; ANTIOXIDANT; ANTHOCYANIN; CYANIDIN 3-O-GLUCOSIDE; GLUCOSIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL INFILTRATION; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; DEPLETION; DNA DAMAGE; DRUG EFFECT; EPIDERMIS HYPERPLASIA; ERYTHEMA; FEMALE; IN VIVO STUDY; INFLAMMATION; LEUKOCYTE; LIPID PEROXIDATION; LONG TERM EXPOSURE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RADIATION EXPOSURE; RADIATION PROTECTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SKIN CARCINOGENESIS; SKIN DEFECT; SKIN EDEMA; SKINFOLD THICKNESS; TOPICAL TREATMENT; ULTRAVIOLET B RADIATION; WESTERN BLOTTING; ANTIOXIDANT ACTIVITY; HAIRLESS MOUSE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; PROTEIN PHOSPHORYLATION; SUN EXPOSURE; ADVERSE EFFECTS; ANIMAL; ANTAGONISTS AND INHIBITORS; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PATHOLOGY; PHYSIOLOGY; RADIATION RESPONSE; RANDOMIZATION; SKIN ABSORPTION; ULTRAVIOLET RADIATION;

ANIMALS; ANTHOCYANINS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUCOSIDES; INFLAMMATION; MICE; MICE, HAIRLESS; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; OXIDATIVE STRESS; RANDOM ALLOCATION; SIGNAL TRANSDUCTION; SKIN ABSORPTION; ULTRAVIOLET RAYS;

EID: 84906510976     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.06.028     Document Type: Article

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