Curcumin inhibits UV radiation-induced skin cancer in SKH-1 mice

Otolaryngology - Head and Neck Surgery (United States)

Volumn 148, Issue 5, 2013, Pages 797-803

  Phillips, Jeffrey ^a   Moore Medlin, Tara ^a   Sonavane, Kunal ^a   Ekshyyan, Oleksandr ^a,b   McLarty, Jerry ^b   Nathan, Cherie Ann O ^a,b  

^a Louisiana State University School of Medicine Shreveport   (United States)

^b LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Chemoprevention; Curcumin; Nutraceuticals; Skin carcinogenesis; Squamous cell carcinoma

Indexed keywords

CURCUMIN; ANTINEOPLASTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; CHEMOPROPHYLAXIS; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFICACY; MOUSE; NONHUMAN; RADIATION DOSE; SKIN CARCINOGENESIS; SKIN CARCINOMA; SKIN PROTECTION; TREATMENT DURATION; TUMOR XENOGRAFT; ULTRAVIOLET B RADIATION; ANIMAL; ARTICLE; DISEASE MODEL; MOUSE STRAIN; ORAL DRUG ADMINISTRATION; RADIATION INDUCED NEOPLASM; SKIN TUMOR; TOPICAL DRUG ADMINISTRATION; ULTRAVIOLET RADIATION;

ADMINISTRATION, ORAL; ADMINISTRATION, TOPICAL; ANIMALS; ANTICARCINOGENIC AGENTS; CURCUMIN; DISEASE MODELS, ANIMAL; MICE; MICE, INBRED STRAINS; NEOPLASMS, RADIATION-INDUCED; SKIN NEOPLASMS; ULTRAVIOLET RAYS;

MLCS; MLOWN;

EID: 84879296809     PISSN: 01945998     EISSN: 10976817     Source Type: Journal    
DOI: 10.1177/0194599813476845     Document Type: Conference Paper

References (27)

1. Netscher D, Leong M, Orengo I, et al. Cutaneous malignancies: melanoma and nonmelanoma types. Plast Reconstr Surg. 2011;127:37e-56e.
2. American Cancer Society. Cancer facts & figures 2011. Atlanta: American Cancer Society; 2011.
3. Rogers HW, Weinstock MA, Harris AR, et al. Incidence estimate of nonmelanoma skin cancer in the United States, 2006. Arch Dermatol. 2010;146:283-287.
4. Bickers DR, Lim HW, Margolis D, et al. The burden of skin diseases: 2004: A joint project of the American Academy of Dermatology Association and the Society for Investigative Dermatology. J Am Acad Dermatol. 2006;55:490-500.
5. Arora A, Attwood J. Common skin cancers and their precursors. Surg Clin North Am. 2009;89:703-712.
6. Matsumura Y, Ananthaswamy HN. Toxic effects of ultraviolet radiation on the skin. Toxicol Appl Pharmacol. 2004;195:298-308.
7. Marquez C, Bair S, Smithberger E, Cherpelis B, Glass L. Systemic retinoids for chemoprevention of non-melanoma skin cancer in high-risk patients. J Drugs Dermatol. 2010;9:753-758.
8. Wright T, Spencer J, Flowers F. Chemoprevention of nonmelanoma skin cancer. J Am Acad Dermatol. 2006;54:933-946.
9. Katiyar S, Elmets C, Katiyar S. Green tea and skin cancer: photoimmunology, angiogenesis and DNA repair. J Nutr Biochem. 2007;18:2872-96.
10. Pari L, Tewas D, Eckel J. Role of curcumin in health and disease. Arch Physiol Biochem. 2008;114:127-149.
11. Cheng A, Hsu C, Lin J, et al. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or premalignant lesions. Anticancer Research. 2001;21:2895-2900.
12. Phillips J, Clark C, Herman-Ferdinandez L, et al. Curcumin inhibits skin squamous cell carcinoma tumor growth in vivo. Otolaryngol Head Neck Surg. 2011;145:58-63.
13. Shehzad A, Khan S, Shehzad O, Lee Y. Curcumin therapeutic promises and bioavailability in colorectal cancer. Drugs Today. 2010;46:523-532.
14. Lin CC, Liu Y, Ho CT, Huang MT. Inhibitory effects of 1,3-bis-(2-substituted-phenyl)-propane-1,3-dione, b-diketone structural analogues of curcumin, on chemical-induced tumor promotion and inflammation in mouse skin. Food Funct. 2011;2:78-83.
15. Agrawal R, Kaur IP. Inhibitory effect of encapsulated curcumin on ultraviolet-induced photoaging in mice. Rejuvenation Res. 2010;13:397-410.
16. Mittal A, Piyathilake C, Hara Y, Katiyar SK. Exceptionally high protection of photocarcinogenesis by topical application of (-)- epigallocatechin-3-gallate in hydrophilic cream in SKH-1 hairless mouse model: relationship to inhibition of UVB-induced global DNA hypomethylation. Neoplasia. 2003;5:555-565.
17. Katiyar SK, Korman NJ, Mukhtar H, Agarwal R. Protective effects of silymarin against photocarcinogenesis in a mouse skin model. J Natl Cancer Inst. 1997;89:556-565.
18. Filip A, Clichici S, Daicoviciu D, et al. Chemopreventive effects of Calluna vulgaris and Vitis vinifera extracts on UVBinduced skin damage in SKH-1 hairless mice. J Physiol Pharmacol. 2011;62:385-392.
19. Afaq F, Khan N, Syed DN, Mukhtar H. Oral feeding of pomegranate fruit extract inhibits early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis. Photochem Photobiol. 2010;86:1318-1326.
20. Butler G, Neale R, Green A, et al. Nonsteroidal antiinflammatory drugs and the risk of actinic keratoses and squamous cell cancers of the skin. J Am Acad Dermatol 2005; 53:966-972.
21. Huang M, Ma W, Yen P, et al. Inhibitory effects of topical application of low doses of curcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and oxidized DNA bases in mouse epidermis. Carcinogenesis. 1997;18:83-88.
22. Limtrakul P, Lipigorngoson S, Namwong O, Apisariyakul A, Dunn F. Inhibitory effect of dietary curcumin on skin carcinogenesis in mice. Cancer Lett. 1997;116:197-203.
23. Dujic J, Kippenberger S, Ramirez-Bosca A, et al. Curcumin in combination with visible light inhibits tumor growth in a xenograft tumor model. Int J Cancer. 2008;124:1422-1428.
24. Tsai K, Lin J, Yang S, et al. Curcumin protects against UVBinduced skin cancers in SKH-1 hairless mouse: analysis of early molecular markers in carcinogenesis. Evid Based Complement Alternat Med. 2012;2012. doi:10.1155/2012/593952.
25. Heng MC. Curcumin targeted signaling pathways: basis for anti-photoaging and anti-carcinogenic therapy. Int J Dermatol. 2010;49:608-622.
26. Meric-Bernstam F, Gonzalez-Angulo A. Targeting the mTOR signaling network for cancer therapy. J Clin Oncol. 2009;27: 2278-2287.
27. Thomas G. The S6 kinase signaling pathway in the control of development and growth. Biol Res. 2002;35:305-313.