메뉴 건너뛰기




Volumn 395, Issue 1-2, 2014, Pages 51-60

4-Hydroxyisoleucine ameliorates fatty acid-induced insulin resistance and inflammatory response in skeletal muscle cells

Author keywords

4 Hydroxyisoleucine; Diabetes; Glucose uptake; Inflammation; Insulin resistance

Indexed keywords

4 HYDROXYISOLEUCINE; AKT SUBSTRATE 160; FATTY ACID; GLUCOSE TRANSPORTER 4; GLYCOGEN SYNTHASE KINASE 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN RECEPTOR SUBSTRATE 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PALMITIC ACID; PROTEIN KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 4-HYDROXYISOLEUCINE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, RAT; ISOLEUCINE; LOC686547 PROTEIN, RAT; MITOGEN ACTIVATED PROTEIN KINASE; SLC2A4 PROTEIN, RAT;

EID: 84906492099     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2014.07.018     Document Type: Article
Times cited : (53)

References (67)
  • 1
    • 0034708832 scopus 로고    scopus 로고
    • The c-Jun NH (2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser 307
    • Aguirre V., Uchida T., Yenush L., Davis R., White M.F. The c-Jun NH (2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser 307. J. Biol. Chem 2000, 275:9047-9054.
    • (2000) J. Biol. Chem , vol.275 , pp. 9047-9054
    • Aguirre, V.1    Uchida, T.2    Yenush, L.3    Davis, R.4    White, M.F.5
  • 3
    • 0032913309 scopus 로고    scopus 로고
    • Role of oxidative stress in diabetic complications: a new perspective on an old paradigm
    • Baynes J.W., Thorpe S.R. Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. Diabetes 1999, 48:1-9.
    • (1999) Diabetes , vol.48 , pp. 1-9
    • Baynes, J.W.1    Thorpe, S.R.2
  • 4
    • 8844255630 scopus 로고    scopus 로고
    • Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction
    • Boden G., Shulman G.I. Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction. Eur. J. Clin. Invest 2002, 32:14-23.
    • (2002) Eur. J. Clin. Invest , vol.32 , pp. 14-23
    • Boden, G.1    Shulman, G.I.2
  • 5
    • 0031014830 scopus 로고    scopus 로고
    • Role of fatty acids in the pathogenesis of insulin resistance and NIDDM
    • Boden G.A. Role of fatty acids in the pathogenesis of insulin resistance and NIDDM. Diabetes 1997, 46:3-10.
    • (1997) Diabetes , vol.46 , pp. 3-10
    • Boden, G.A.1
  • 6
    • 38849199866 scopus 로고    scopus 로고
    • Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice
    • Bonnard C., Durand A., Peyrol S., Chanseaume E., Chauvin M.A., Morio B., et al. Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice. J. Clin. Invest 2008, 118:789-800.
    • (2008) J. Clin. Invest , vol.118 , pp. 789-800
    • Bonnard, C.1    Durand, A.2    Peyrol, S.3    Chanseaume, E.4    Chauvin, M.A.5    Morio, B.6
  • 8
    • 19944433322 scopus 로고    scopus 로고
    • The extracellular signal regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis
    • Bost F., Aouadi M., Caron L., Even P., Belmonte N., Prot M., et al. The extracellular signal regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis. Diabetes 2005, 54:402-411.
    • (2005) Diabetes , vol.54 , pp. 402-411
    • Bost, F.1    Aouadi, M.2    Caron, L.3    Even, P.4    Belmonte, N.5    Prot, M.6
  • 9
    • 0032760014 scopus 로고    scopus 로고
    • 4-Hydroxyisoleucine: experimental evidence of its insulinotropic and antidiabetic properties
    • Broca C., Rene G., Pierre P., Yves S., Manteghetti M., Tournier M., et al. 4-Hydroxyisoleucine: experimental evidence of its insulinotropic and antidiabetic properties. Am. J. Physiol 1999, 277:E617-E623.
    • (1999) Am. J. Physiol , vol.277
    • Broca, C.1    Rene, G.2    Pierre, P.3    Yves, S.4    Manteghetti, M.5    Tournier, M.6
  • 10
    • 0034598962 scopus 로고    scopus 로고
    • 4-Hydroxyisoleucine: effects of synthetic and natural analogues on insulin secretion
    • Broca C., Manteghetti M., Gross R., Baissac Y., Jacob M., Petit P., et al. 4-Hydroxyisoleucine: effects of synthetic and natural analogues on insulin secretion. Eur. J. Pharmacol 2000, 390:339-435.
    • (2000) Eur. J. Pharmacol , vol.390 , pp. 339-435
    • Broca, C.1    Manteghetti, M.2    Gross, R.3    Baissac, Y.4    Jacob, M.5    Petit, P.6
  • 12
    • 0037341276 scopus 로고    scopus 로고
    • Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: potential role of p38 in the downregulation of GLUT4 expression
    • Carlson C.J., Koterski S., Sciotti R.J., Poccard G.B., Rondinone C.M. Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: potential role of p38 in the downregulation of GLUT4 expression. Diabetes 2003, 52:634-641.
    • (2003) Diabetes , vol.52 , pp. 634-641
    • Carlson, C.J.1    Koterski, S.2    Sciotti, R.J.3    Poccard, G.B.4    Rondinone, C.M.5
  • 13
    • 0038532298 scopus 로고    scopus 로고
    • Role of ceramide but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids
    • Chavez J.A., Knotts T.A., Wang L.P., Li G., Dobrowsky R.T., Florant G.L. Role of ceramide but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids. J. Biol. Chem 2003, 278:10297-10303.
    • (2003) J. Biol. Chem , vol.278 , pp. 10297-10303
    • Chavez, J.A.1    Knotts, T.A.2    Wang, L.P.3    Li, G.4    Dobrowsky, R.T.5    Florant, G.L.6
  • 14
    • 33644680390 scopus 로고    scopus 로고
    • Conjugated linoleic acid promotes human adipocyte insulin resistance through NFκB-dependent cytokine production
    • Chung S., Brown J.M., Provo J.N., Hopkins R., Mclntosh M.K. Conjugated linoleic acid promotes human adipocyte insulin resistance through NFκB-dependent cytokine production. J. Biol. Chem 2005, 280:38445-38456.
    • (2005) J. Biol. Chem , vol.280 , pp. 38445-38456
    • Chung, S.1    Brown, J.M.2    Provo, J.N.3    Hopkins, R.4    Mclntosh, M.K.5
  • 16
    • 0031465447 scopus 로고    scopus 로고
    • Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen activated protein kinase
    • De Fea K., Roth R.A. Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen activated protein kinase. J. Biol. Chem 1997, 272:31400-31406.
    • (1997) J. Biol. Chem , vol.272 , pp. 31400-31406
    • De Fea, K.1    Roth, R.A.2
  • 18
    • 33750572410 scopus 로고    scopus 로고
    • Differential effects of palmitate and palmitoleate on insulin action and glucose utilization in rat L6 skeletal muscle cells
    • Dimopoulos N., Watson M., Sakamoto K., Hundal H.S. Differential effects of palmitate and palmitoleate on insulin action and glucose utilization in rat L6 skeletal muscle cells. Biochem. J. 2006, 399:473-481.
    • (2006) Biochem. J. , vol.399 , pp. 473-481
    • Dimopoulos, N.1    Watson, M.2    Sakamoto, K.3    Hundal, H.S.4
  • 19
    • 0032954778 scopus 로고    scopus 로고
    • Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity
    • Dresner A., Laurent D., Marcucci M., Griffin M.E., Dufour S., Cline G.W., et al. Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. J. Clin. Invest 1999, 103:253-259.
    • (1999) J. Clin. Invest , vol.103 , pp. 253-259
    • Dresner, A.1    Laurent, D.2    Marcucci, M.3    Griffin, M.E.4    Dufour, S.5    Cline, G.W.6
  • 20
    • 36048974904 scopus 로고    scopus 로고
    • Effect of fenugreek (Trigonella foenum-graecum L) seeds on serum parameters in normal and streptozotocin-induced diabetic rats
    • Eidi A., Eidi M., Sokhteh M. Effect of fenugreek (Trigonella foenum-graecum L) seeds on serum parameters in normal and streptozotocin-induced diabetic rats. Nutr. Res 2007, 27:728-733.
    • (2007) Nutr. Res , vol.27 , pp. 728-733
    • Eidi, A.1    Eidi, M.2    Sokhteh, M.3
  • 21
    • 0027332738 scopus 로고
    • Tumor necrosis factor-alpha suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates
    • Feinstein R., Kanety H., Papa M.Z., Lunenfeld B., Karasik A. Tumor necrosis factor-alpha suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates. J. Biol. Chem 1993, 268:26055-26058.
    • (1993) J. Biol. Chem , vol.268 , pp. 26055-26058
    • Feinstein, R.1    Kanety, H.2    Papa, M.Z.3    Lunenfeld, B.4    Karasik, A.5
  • 22
    • 0037339991 scopus 로고    scopus 로고
    • Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes
    • Fujishiro M., Gotoh Y., Katagiri H., Sakoda H., Ogihara T., Anai M., et al. Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes. Mol. Endocrinol 2003, 17:487-497.
    • (2003) Mol. Endocrinol , vol.17 , pp. 487-497
    • Fujishiro, M.1    Gotoh, Y.2    Katagiri, H.3    Sakoda, H.4    Ogihara, T.5    Anai, M.6
  • 23
    • 77956921023 scopus 로고    scopus 로고
    • The effects of palmitate on hepatic insulin resistance are mediated by NADPH Oxidase 3-derived reactive oxygen species through JNK and p38MAPK pathways
    • Gao D., Nong S., Huang X., Lu Y., Zhao H., Lin Y., et al. The effects of palmitate on hepatic insulin resistance are mediated by NADPH Oxidase 3-derived reactive oxygen species through JNK and p38MAPK pathways. J. Biol. Chem 2010, 285:29965-29973.
    • (2010) J. Biol. Chem , vol.285 , pp. 29965-29973
    • Gao, D.1    Nong, S.2    Huang, X.3    Lu, Y.4    Zhao, H.5    Lin, Y.6
  • 25
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil G.S. Inflammation and metabolic disorders. Nature 2006, 444:860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 26
    • 33645860825 scopus 로고    scopus 로고
    • Reactive oxygen species have a causal role in multiple forms of insulin resistance
    • Houstis N., Rosen E.D., Lander E.S. Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature 2006, 440:944-948.
    • (2006) Nature , vol.440 , pp. 944-948
    • Houstis, N.1    Rosen, E.D.2    Lander, E.S.3
  • 27
    • 33947596679 scopus 로고    scopus 로고
    • The GLUT4 glucose transporter
    • Huang S., Czech M.P. The GLUT4 glucose transporter. Cell Metab 2007, 5:237-252.
    • (2007) Cell Metab , vol.5 , pp. 237-252
    • Huang, S.1    Czech, M.P.2
  • 28
    • 41149142315 scopus 로고    scopus 로고
    • Acute and chronic treatment of L-isoleucine ameliorates glucose metabolism in glucose-intolerant and diabetic mice
    • Ikehara O., Kawasaki N., Maezono K., Komatsu M., Konishi A. Acute and chronic treatment of L-isoleucine ameliorates glucose metabolism in glucose-intolerant and diabetic mice. Biol. Pharm. Bull 2008, 31:469-472.
    • (2008) Biol. Pharm. Bull , vol.31 , pp. 469-472
    • Ikehara, O.1    Kawasaki, N.2    Maezono, K.3    Komatsu, M.4    Konishi, A.5
  • 29
    • 0036300538 scopus 로고    scopus 로고
    • Lipid induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IκBα
    • Itani S.I., Ruderman N.B., Frank S., Boden G. Lipid induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IκBα. Diabetes 2002, 51:2005-2011.
    • (2002) Diabetes , vol.51 , pp. 2005-2011
    • Itani, S.I.1    Ruderman, N.B.2    Frank, S.3    Boden, G.4
  • 30
    • 84870251086 scopus 로고    scopus 로고
    • 4-Hydroxyisoleucine stimulates glucose uptake by increasing surface GLUT4 level in skeletal muscle cells via phosphatidylinositol-3-kinase-dependent pathway
    • Jaiswal N., Maurya C.K., Venkateswarlu K., Sukanya P., Srivastava A.K., Narender T., et al. 4-Hydroxyisoleucine stimulates glucose uptake by increasing surface GLUT4 level in skeletal muscle cells via phosphatidylinositol-3-kinase-dependent pathway. Eur. J. Nutr 2012, 51:893-898.
    • (2012) Eur. J. Nutr , vol.51 , pp. 893-898
    • Jaiswal, N.1    Maurya, C.K.2    Venkateswarlu, K.3    Sukanya, P.4    Srivastava, A.K.5    Narender, T.6
  • 31
    • 33845881411 scopus 로고    scopus 로고
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes
    • Kahn S.E., Hull R.L., Utzscheider K.M. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006, 444:840-846.
    • (2006) Nature , vol.444 , pp. 840-846
    • Kahn, S.E.1    Hull, R.L.2    Utzscheider, K.M.3
  • 32
    • 52049096635 scopus 로고    scopus 로고
    • Branched-chain amino acid-enriched supplementation improves insulin resistance in patients with chronic liver disease
    • Kawaguchi T., Nagao Y., Matsuoka H., Ide T., Sata M. Branched-chain amino acid-enriched supplementation improves insulin resistance in patients with chronic liver disease. Int. J. Mol. Med 2008, 22:105-112.
    • (2008) Int. J. Mol. Med , vol.22 , pp. 105-112
    • Kawaguchi, T.1    Nagao, Y.2    Matsuoka, H.3    Ide, T.4    Sata, M.5
  • 33
    • 0036434431 scopus 로고    scopus 로고
    • Insulin regulation of glucose uptake: a complex interplay of intracellular signalling pathways
    • Khan A.H., Pessin J.E. Insulin regulation of glucose uptake: a complex interplay of intracellular signalling pathways. Diabetologia 2002, 45:1475-1483.
    • (2002) Diabetologia , vol.45 , pp. 1475-1483
    • Khan, A.H.1    Pessin, J.E.2
  • 34
    • 0032040381 scopus 로고    scopus 로고
    • Bradykinin directly triggers GLUT4 translocation via an insulin-independent pathway
    • Kishi K., Muromoto N., Nakaya Y., Miyata I., Hagi A., Hayashi H., et al. Bradykinin directly triggers GLUT4 translocation via an insulin-independent pathway. Diabetes 1998, 47:550-558.
    • (1998) Diabetes , vol.47 , pp. 550-558
    • Kishi, K.1    Muromoto, N.2    Nakaya, Y.3    Miyata, I.4    Hagi, A.5    Hayashi, H.6
  • 35
    • 84865187080 scopus 로고    scopus 로고
    • Supplementation with branched-chain amino acids attenuates hepatic apoptosis in rats with chronic liver disease
    • Kuwahata M., Kubota H., Kanouchi H., Ito S., Ogawa A., Kobayashi Y., et al. Supplementation with branched-chain amino acids attenuates hepatic apoptosis in rats with chronic liver disease. Nutr. Res 2012, 32:522-529.
    • (2012) Nutr. Res , vol.32 , pp. 522-529
    • Kuwahata, M.1    Kubota, H.2    Kanouchi, H.3    Ito, S.4    Ogawa, A.5    Kobayashi, Y.6
  • 36
    • 28944446431 scopus 로고    scopus 로고
    • The many faces of PPAR gamma
    • Lehrke M., Lazar M.A. The many faces of PPAR gamma. Cell 2005, 123:993-999.
    • (2005) Cell , vol.123 , pp. 993-999
    • Lehrke, M.1    Lazar, M.A.2
  • 37
    • 12344305124 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and type 2 diabetes
    • Lowell B.B., Shulman G.I. Mitochondrial dysfunction and type 2 diabetes. Science 2005, 307:384-387.
    • (2005) Science , vol.307 , pp. 384-387
    • Lowell, B.B.1    Shulman, G.I.2
  • 39
    • 0036092239 scopus 로고    scopus 로고
    • Banting lecture: 2001: dysregulation of fatty acid metabolism in the aetiology of type 2 diabetes
    • McGarry J.D. Banting lecture: 2001: dysregulation of fatty acid metabolism in the aetiology of type 2 diabetes. Diabetes 2002, 51:7-18.
    • (2002) Diabetes , vol.51 , pp. 7-18
    • McGarry, J.D.1
  • 40
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65:55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 41
    • 27944478894 scopus 로고    scopus 로고
    • 4-Hydroxyisoleucine an unusual amino acid as antidyslipidemic and antihyperglycemic agent
    • Narender T., Puri A., Shweta, Khaliq T., Saxena R., Bhatia G., et al. 4-Hydroxyisoleucine an unusual amino acid as antidyslipidemic and antihyperglycemic agent. Bioorg. Med. Chem. Lett 2006, 16:293-296.
    • (2006) Bioorg. Med. Chem. Lett , vol.16 , pp. 293-296
    • Narender, T.1    Puri, A.2    Shweta, S.3    Khaliq, T.4    Saxena, R.5    Bhatia, G.6
  • 42
    • 0344304678 scopus 로고    scopus 로고
    • Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association
    • Nesto R.W., Bell D., Bonow R.O., Fonseca V., Grundy S.M., Horton E.S., et al. Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. Circulation 2003, 108:2941-2948.
    • (2003) Circulation , vol.108 , pp. 2941-2948
    • Nesto, R.W.1    Bell, D.2    Bonow, R.O.3    Fonseca, V.4    Grundy, S.M.5    Horton, E.S.6
  • 45
    • 33748202567 scopus 로고    scopus 로고
    • New insights into the pathogenesis of insulin resistance in humans using magnetic resonance spectroscopy
    • Petersen K.F., Shulman G.I. New insights into the pathogenesis of insulin resistance in humans using magnetic resonance spectroscopy. Obesity 2006, 14:34S-40S.
    • (2006) Obesity , vol.14
    • Petersen, K.F.1    Shulman, G.I.2
  • 46
    • 1442275317 scopus 로고    scopus 로고
    • Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes
    • Pickup J.C. Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes. Diabetes Care 2004, 3:813-823.
    • (2004) Diabetes Care , vol.3 , pp. 813-823
    • Pickup, J.C.1
  • 47
    • 84876361256 scopus 로고    scopus 로고
    • Diastereomeric mixture of calophyllic acid and isocalophyllic acid stimulates glucose uptake in skeletal muscle cells: involvement of PI-3-kinase- and ERK1/2-dependent pathways
    • Prasad J., Maurya C.K., Pandey J., Jaiswal N., Madhur G., Srivastava A.K., et al. Diastereomeric mixture of calophyllic acid and isocalophyllic acid stimulates glucose uptake in skeletal muscle cells: involvement of PI-3-kinase- and ERK1/2-dependent pathways. Mol. Cell. Endocrinol 2013, 370:11-19.
    • (2013) Mol. Cell. Endocrinol , vol.370 , pp. 11-19
    • Prasad, J.1    Maurya, C.K.2    Pandey, J.3    Jaiswal, N.4    Madhur, G.5    Srivastava, A.K.6
  • 48
    • 0038755467 scopus 로고    scopus 로고
    • High levels of palmitic acid lead to insulin resistance due to changes in the level of phosphorylation of the insulin receptor and insulin receptor substrate-1
    • Reynoso R., Salgado L.M., Calderon V. High levels of palmitic acid lead to insulin resistance due to changes in the level of phosphorylation of the insulin receptor and insulin receptor substrate-1. Mol. Cell. Biochem 2003, 246:155-162.
    • (2003) Mol. Cell. Biochem , vol.246 , pp. 155-162
    • Reynoso, R.1    Salgado, L.M.2    Calderon, V.3
  • 50
    • 0030059853 scopus 로고    scopus 로고
    • The pathogenesis of type II diabetes mellitus. A polygenic disease
    • Sacks D.B., McDonald J.M. The pathogenesis of type II diabetes mellitus. A polygenic disease. Am. J. Clin. Pathol 1996, 105:149-156.
    • (1996) Am. J. Clin. Pathol , vol.105 , pp. 149-156
    • Sacks, D.B.1    McDonald, J.M.2
  • 51
    • 0035856949 scopus 로고    scopus 로고
    • Insulin signalling and the regulation of glucose and lipid metabolism
    • Saltiel A.R., Kahn C.R. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 2001, 414:799-806.
    • (2001) Nature , vol.414 , pp. 799-806
    • Saltiel, A.R.1    Kahn, C.R.2
  • 53
    • 0023025947 scopus 로고
    • Effect of fenugreek seeds and leaves on blood glucose and serum insulin responses in human subjects
    • Sharma R.D. Effect of fenugreek seeds and leaves on blood glucose and serum insulin responses in human subjects. Nutr. Res 1986, 6:1353-1364.
    • (1986) Nutr. Res , vol.6 , pp. 1353-1364
    • Sharma, R.D.1
  • 55
    • 0033927667 scopus 로고    scopus 로고
    • Cellular mechanisms of insulin resistance
    • Shulman G.I. Cellular mechanisms of insulin resistance. J. Clin. Invest 2000, 106:171-175.
    • (2000) J. Clin. Invest , vol.106 , pp. 171-175
    • Shulman, G.I.1
  • 56
    • 4744344777 scopus 로고    scopus 로고
    • Fatty acid induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B
    • Sinha S., Perdomo G., Brown N.F., O'Doherty R.M. Fatty acid induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B. J. Biol. Chem 2004, 279:41294-41301.
    • (2004) J. Biol. Chem , vol.279 , pp. 41294-41301
    • Sinha, S.1    Perdomo, G.2    Brown, N.F.3    O'Doherty, R.M.4
  • 57
    • 78649817454 scopus 로고    scopus 로고
    • NOD2 activation induces muscle cell-autonomous innate immune responses and insulin resistance
    • Tamrakar A.K., Schertzer J.D., Chiu T.T., Foley K.P., Bilan P.J., Philpott D.J., et al. NOD2 activation induces muscle cell-autonomous innate immune responses and insulin resistance. Endocrinology 2010, 151:5624-5637.
    • (2010) Endocrinology , vol.151 , pp. 5624-5637
    • Tamrakar, A.K.1    Schertzer, J.D.2    Chiu, T.T.3    Foley, K.P.4    Bilan, P.J.5    Philpott, D.J.6
  • 58
    • 79958071889 scopus 로고    scopus 로고
    • Pongamol from Pongamia pinnata stimulates glucose uptake by increasing surface GLUT4 level in skeletal muscle cells
    • Tamrakar A.K., Jaiswal N., Yadav P.P., Maurya R., Srivastava A.K. Pongamol from Pongamia pinnata stimulates glucose uptake by increasing surface GLUT4 level in skeletal muscle cells. Mol. Cell. Endocrinol 2011, 339:98-104.
    • (2011) Mol. Cell. Endocrinol , vol.339 , pp. 98-104
    • Tamrakar, A.K.1    Jaiswal, N.2    Yadav, P.P.3    Maurya, R.4    Srivastava, A.K.5
  • 59
    • 70449724835 scopus 로고    scopus 로고
    • Cellular mechanisms of insulin resistance: role of stress regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation
    • Tanti J.F., Jager J. Cellular mechanisms of insulin resistance: role of stress regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation. Curr. Opin. Pharmacol 2009, 9:1-10.
    • (2009) Curr. Opin. Pharmacol , vol.9 , pp. 1-10
    • Tanti, J.F.1    Jager, J.2
  • 60
    • 41649093318 scopus 로고    scopus 로고
    • Inflammatory mechanisms in the regulation of insulin resistance
    • Tilg H., Moschen A.R. Inflammatory mechanisms in the regulation of insulin resistance. Mol. Med 2008, 14:222-231.
    • (2008) Mol. Med , vol.14 , pp. 222-231
    • Tilg, H.1    Moschen, A.R.2
  • 61
    • 0035432971 scopus 로고    scopus 로고
    • Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atypical protein kinase C (zeta/lambda) activities
    • Tremblay F., Lavigne C., Jacques H., Marette A. Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atypical protein kinase C (zeta/lambda) activities. Diabetes 2001, 50:1901-1910.
    • (2001) Diabetes , vol.50 , pp. 1901-1910
    • Tremblay, F.1    Lavigne, C.2    Jacques, H.3    Marette, A.4
  • 62
    • 0032882958 scopus 로고    scopus 로고
    • GLUT-4myc ectopic expression in L6 myoblasts generates a GLUT-4-specific pool conferring insulin sensitivity
    • Ueyama A., Yaworsky K.L., Wang Q., Ebina Y., Klip A. GLUT-4myc ectopic expression in L6 myoblasts generates a GLUT-4-specific pool conferring insulin sensitivity. Am. J. Physiol 1999, 277:E572-E578.
    • (1999) Am. J. Physiol , vol.277
    • Ueyama, A.1    Yaworsky, K.L.2    Wang, Q.3    Ebina, Y.4    Klip, A.5
  • 63
    • 0033049422 scopus 로고    scopus 로고
    • Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts
    • Wang Q., Somwar R., Bilan P.J., Liu Z., Jin J., Woodgett J.R., et al. Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts. Mol. Cell. Biol 1999, 19:4008-4018.
    • (1999) Mol. Cell. Biol , vol.19 , pp. 4008-4018
    • Wang, Q.1    Somwar, R.2    Bilan, P.J.3    Liu, Z.4    Jin, J.5    Woodgett, J.R.6
  • 64
    • 10344236432 scopus 로고    scopus 로고
    • Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes
    • Watson R.T., Kanzaki M., Pessin J.E. Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes. Endocr. Rev 2004, 25:177-204.
    • (2004) Endocr. Rev , vol.25 , pp. 177-204
    • Watson, R.T.1    Kanzaki, M.2    Pessin, J.E.3
  • 65
    • 0036710280 scopus 로고    scopus 로고
    • IRS proteins and the common path to diabetes
    • White M.F. IRS proteins and the common path to diabetes. Am. J. Physiol. Endocrinol. Metab 2002, 283:413-422.
    • (2002) Am. J. Physiol. Endocrinol. Metab , vol.283 , pp. 413-422
    • White, M.F.1
  • 66
    • 0025761472 scopus 로고
    • A common denominator linking glycogen metabolism, nuclear oncogenes and development
    • Woodgett J.R. A common denominator linking glycogen metabolism, nuclear oncogenes and development. Trends Biochem. Sci 1991, 16:177-181.
    • (1991) Trends Biochem. Sci , vol.16 , pp. 177-181
    • Woodgett, J.R.1
  • 67
    • 34249680883 scopus 로고    scopus 로고
    • Increasing dietary leucine intake reduces diet-induced obesity and improves glucose and cholesterol metabolism in mice via multimechanisms
    • Zhang Y., Guo K., LeBlanc R.E., Loh D., Schwartz G.J., Yu Y.H. Increasing dietary leucine intake reduces diet-induced obesity and improves glucose and cholesterol metabolism in mice via multimechanisms. Diabetes 2007, 56:1647-1654.
    • (2007) Diabetes , vol.56 , pp. 1647-1654
    • Zhang, Y.1    Guo, K.2    LeBlanc, R.E.3    Loh, D.4    Schwartz, G.J.5    Yu, Y.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.