Rebuilding a macromolecular membrane complex at the atomic scale: Case of the Kir6.2 potassium channel coupled to the muscarinic acetylcholine receptor M2

Proteins: Structure, Function and Bioinformatics

Volumn 82, Issue 9, 2014, Pages 1694-1707

  Sapay, Nicolas ^a   Estrada Mondragon, Argel ^a,b,c,d   Moreau, Christophe ^a,b,c   Vivaudou, Michel ^a,b,c   Crouzy, Serge ^a  

^a UNIV GRENOBLE ALPES   (France)

^b INSTITUT DE BIOLOGIE STRUCTURALE   (France)

^c CEA GRENOBLE   (France)

^d INSTITUTO DE NEUROBIOLOGÍA   (Mexico)

Author keywords

G protein coupled receptor; Ion channel; Membrane protein; Protein protein docking

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; HOMODIMER; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; ION CHANNEL; ION CHANNEL COUPLED RECEPTOR; MEMBRANE PROTEIN; MEMBRANE RECEPTOR; MU OPIATE RECEPTOR; MUSCARINIC M2 RECEPTOR; POTASSIUM CHANNEL KV1.2; UNCLASSIFIED DRUG; HYBRID PROTEIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; MULTIPROTEIN COMPLEX;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVATION; CHEMICAL STRUCTURE; CHIMERA; CLINICAL PROTOCOL; CRYSTAL STRUCTURE; EXPERIMENTAL STUDY; MACROMOLECULAR MEMBRANE COMPLEX; MEMBRANE BIOLOGY; MOLECULAR BIOLOGY; MOLECULAR DOCKING; MOLECULAR MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; CHANNEL GATING; GENETIC PROCEDURES; METABOLISM; PATCH CLAMP TECHNIQUE; ULTRASTRUCTURE;

BIOSENSING TECHNIQUES; ION CHANNEL GATING; MOLECULAR DOCKING SIMULATION; MULTIPROTEIN COMPLEXES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN ENGINEERING; RECEPTOR, MUSCARINIC M2; RECEPTORS, CXCR4; RECEPTORS, OPIOID, MU; RECOMBINANT FUSION PROTEINS;

EID: 84906320597     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24521     Document Type: Article

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